Light harvesting luminescent multichromophores that are configured upon excitation to transfer energy to, and amplify the emission from, an acceptor signaling chromophore in energy-receiving proximity therewith are provided. Also provided are compositions for labelling a target. The labelling composition may include a donor light harvesting multichromophore and an acceptor signaling chromophore in energy-receiving proximity to the donor light harvesting multichromophore. Also provided is an aqueous composition for labelling a target, including: a donor light harvesting multichromophore; an acceptor signaling chromophore in energy-receiving proximity therewith; and a sensor biomolecule. Methods for using the subject compositions are also provided.

Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (SCNP), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease.

The adhesive system of the invention is especially useful in bonding replacement windows into vehicles. They allow for sufficient working time while still realizing a fast drive away time. The adhesive system is comprised of a moisture curable adhesive and a cure accelerator that may be applied using a simple single caulk gun and may be applied at ambient temperatures such as −10° C. and about 45° C. The cure accelerator is comprised of a polyol having a backbone that has at least one amine in the backbone. The moisture curable adhesive typically is comprised of an isocyanate terminated prepolymer.

A bituminous composition is used as an adhesive binder. The bituminous composition has at least one acidic additive of general formula (I): R—(COOH)z in which R is a linear or branched, saturated or unsaturated hydrocarbon-based chain having from 4 to 68 carbon atoms, preferably from 4 to 54 carbon atoms, more preferentially from 4 to 36 carbon atoms and z is an integer ranging from 1 to 4, preferably from 2 to 4.

Certain aspects pertain to methods of fabricating an optical device on a substantially transparent substrate that include a pre-deposition operation that removes a width of lower conductor layer at a distance from the outer edge of the substrate to form a pad at the outer edge. The pad and any deposited layers of the optical device may be removed in a post edge deletion operation.

There are provided an adhesive for a solar-cell back sheet having an excellent curing rate and being capable of exhibiting excellent adhesive performance by short-term aging, and also a polyol composition used for the adhesive, a solar-cell back sheet using the adhesive, and a solar-cell module using the sheet. The adhesive for a solar-cell back sheet contains, as essential components, at least one hydroxyl group-containing resin (A) selected from a polyester polyurethane polyol (A1), a polyester polyol (A2), a hydroxyl group-containing (meth)acrylic resin (A3), and a hydroxyl group-containing fluorocarbon resin (A4), a polyisocyanate (B), and a cyclic amide compound (C).

Articles of apparel include: (a) a garment structure having one or more fabric elements structured and arranged to provide a close fit to at least one predetermined portion of a body (e.g., area(s) of the body for which enhanced position sensing and/or feedback are desired, such as the lower back, the arch of the foot, etc.); and (b) a body position feedback system engaged with or integrally formed as part of the garment structure. The body position feedback system may apply higher tensile or constricting forces to selected portions of the wearer's body, which can help stimulate or interact with nerves and deep tissue receptors located in various portions of the body. The increased forces at selected locations of the body give the wearer sensory feedback regarding the position or orientation of these parts of the body and can improve or accelerate development of “muscle memory.”

A device with a stationary portion and a rotatable portion, wherein the rotatable portion is lifted to form a substantially L-shaped bracket. Device is configured to be disposed on the forehead of the wearer, preferably coupled with protective headgear. When the rotatable portion is lifted, the bracket is configured for receiving an edge of eyewear. When the eyewear is pulled upward and back due to forces exerted by straps disposed around a user's head, the bracket exerts an equal and opposite force on the edge of the eyewear, holding the eyewear in place. Bracket may include grips for easier use in inclement weather or when the user's hands are otherwise encumbered.

Joint Lib Dem and Conservative call for demolition plans to be scrapped.

Native Instruments has announced a sale on Sonokinetic, offering up to 70% off on its orchestral and cinematic instrument libraries for Kontakt for a limited time. Playful, independent, and unique, Sonokinetic phrase-based instruments bring dazzle and delight to every composition. Now with 70% off the collection, 50% off 15 individual instruments, and the brand-new Ibrido […]

The post Get up to 70% off Sonokinetic composition tools at Native Instruments appeared first on rekkerd.org.

'Our foray into sanitizers is an effort to help the fight against Covid-19'

There is no market for me today because every brand in the category has convinced the consumer that they need to look fair to be successful in life.

When violinist Anne Akiko Meyers embarked on a new interpretation of Philip Glass' "Metamorphosis ," the composer directed her to his longtime collaborator Michael Reisman. Turns out Reisman was already collaborating with Meyers in her new release in an arrangement of Arvo Pärt's "Fratres." These two meditative pieces on Meyers' album Mirror in Mirror (itself a reference to Pärt) contribute to a whole characterized by haunting beauty—featuring lullabies and sunken ships. "You have to create this beautiful sonic world full of color and movement and breath, and to make it sing, yet while sculpting these long, slow notes," says Meyers of Reisman's adaptation. "It felt to me like color coating a glacier." Listen to the full conversation between Of Note's Katy Henriksen and violinist Anne Akiko Meyers by clicking on the streaming link above.

A new recording from Philippe Quint and Marta Aznavoorian proves Charlie Chaplin is as relevant today as he was in his heyday. His legacy in visionary musical genius continues to be celebrated with "Chaplin's Smile," a collection of Chaplin's songs arranged for violin and piano. "He has a very amazing spin on a melody," says Aznavoorian, who was inspired by Chaplin's emotional and character-driven compositional style. "There's an incredible dichotomy of happiness and sadness in his melodies, and that is mirrored by what's happening in his films." Listen to the full interview between Quint, Aznavoorian and Of Note's Katy Henriksen with the streaming link above.

Harpist Yolanda Kondonassis’ newest album “dreams, soars and levitates” through an intricately flowing compositional architecture with the inclusion of a newly commissioned harp concerto by Pulitzer Prize-winning composer Jennifer Higdon . “The idea was the interplay and the precociousness, and the childlike wonder,” Kondonassis elaborates on how Higdon encompassed her emotions in the composition. “She really impressed upon us that this is fluid and full of wonder, rather than the somnambulant kind of experience.” Kondonassis’ album “American Rapture” expands upon how North American compositions have developed through three generations and features the Rochester Philharmonic Orchestra, directed by Ward Stare. Listen to the full interview between Kondonassis, Stare and Of Note’s Katy Henriksen with the streaming link above.

Violinist Itamar Zorman navigated exotic Israeli scales and modes to release his newest album “Evocation,” which highlights distinctive works by German-born Israeli composer Paul Ben-Haim. “There is a really delicate but wonderful balance between the emotional content and the technical form of the piece, and the analytical part of it,” Zorman explains about reflecting Ben-Haim’s multi-cultural influenced compositions. Listen to the full interview between Zorman and Of Note’s Katy Henriksen with the streaming link above.

Foodservice giant Sysco Corp. (SYY) has been significantly impacted by the coronavirus pandemic that has forced many of its customers such as restaurants, office cafeterias and hospitality facilities to remain temporarily closed. However, the company said it is seeing weekly improvements and expects this trend to continue. Sysco's primary customer base is the restaurant industry.

BUILT in 1962 and nestled in a blue-ribbon locale, this big, brick Sandy Bay home is just a walk from anything a family might need.

The ACT Government's decision ends weeks of uncertainty about when the gradual return to "normal" lessons would begin. It comes as Opposition Leader Alistair Coe tells ABC radio that the coronavirus pandemic has ended.

WA's Chamber of Commerce and Industry releases a damning assessment of newly-elected Opposition Leader Liza Harvey's economic policies, saying they put the state's budget repair at risk.

WA Liberal MPs distance themselves from their new leader's policy direction, including contentious moves to abandon the Western Power sale and steer away from supporting deregulated trading hours, after strong criticism from the business lobby.

Australia's livestock feed supplies are under threat due to the drought, which is putting pressure on both domestic customers and the export market.

The Victorian Government said ongoing conflict between councillors had reduced the respect for, and standing of, the council in the community.

The Victorian Opposition says the Government needs to release reports into how Steelvision got a grant to set up in the Latrobe Valley months before it went into administration, leaving millions in debt.

Submitted by Deidra Herring: I am pleased to announce several Research & Education interim positions for the 2020 summer term and fall semester in place of David Lincove, who retired on April 30.  Kapil Vasudev will serve as the Interim History Librarian under the College of Arts and Sciences.  Carly Dearborn will serve as the […]

Four years ago, Portland voters approved a 10-cents-a-gallon gas tax to fund road projects. Four years later, the tax is up for renewal. But this time around, the debate around the tax is limited.

(California Court of Appeal) - Held that the City of Pomona violated the terms of a 1993 ballot initiative prohibiting the construction of additional billboards within city limits. A citizen group challenged the city council's decision to extend a pre-existing agreement with an outdoor advertising company when the arrangement expired in 2014. Affirmed the granting of a writ of mandate.

Collection Of Folk, Pop, World And Jazz Originals Tells A Tale Of Love In Many Guises;

Two of Colorado’s top offensive linemen from the 2019 season are in the midst of preparing for the NFL Draft.

In June of 2016, Tyler Lytle made the journey from his home in California to Boulder so he could personally tell Colorado coaches that he wanted to play for them.

The U.S. Federal Highway Administration has an opening for a position that closes June 1, 2020.

Clinton Cash - do you trust Bill and Hillary Clinton in positions of power Continue reading →

The response of Senator Richard Blumenthal to my letter in opposition to the Trans-Pacific Partnership (TPP). Ask yourselves how American labor can compete against Vietnamese workers earning on average $0.56 per hour. Continue reading →

Bernie Sanders calls out Hillary Clinton to announce her position on the Trans-Pacific Partnership (TPP) agreement; however, Hillary Clinton refuses to reveal her position, hoping that the agreement will be passed and she won't have to take a position. Continue reading →

Dans ce monde où les business model des entreprises et encore plus les technologies sont en rupture, le challenge est le même : rester en contact avec le consommateur hyper connecté d’aujourd’hui. Ce challenge peut être vu comme un véritable cauchemar ou à l’inverse, considéré comme la prochaine grande opportunité pour les entreprises. Elles sont obligées d’aller au-delà des prévisions, en identifiant et capitalisant sur des opportunités que d’autres entreprises ne voient pas.

IBM positioned as the Leader in the Gartner Magic Quadrant for Data Center Outsourcing and Hybrid Infrastructure Managed Services, Asia Pacific

Jules Hedges has written a thought-provoking blog post, On compositionality where he connects the familiar idea of compositionality to the idea of emergent effects in nature, where systems can be understood as either having compositional properties or emergent properties.

The key point about emergent systems is that they are hard to understand, and this is as true for engineering as it is for science. He goes on to say "As a final thought, I claim that compositionality is extremely delicate, and that it is so powerful that it is worth going to extreme lengths to achieve it", so that avoiding emergent effects is a characteristic of good programming language design.

Some thoughts:

1. His examples of emergent systems are biology and game theory from an economic perspective. I would add to this list physics: of his co-authored paper showing that the spectral gap is undecidable, David Pérez-García said "For example, our results show that adding even a single particle to a lump of matter, however large, could in principle dramatically change its properties."
2. Spolsky's famous characterisation of interfaces built on shaky foundations as Leaky abstractions to me makes the distinction between compositional and emergent systems a little less than sharp.
3. We could talk endlessly about the list of what he regards as compositionality-breaking features of PLs. The evils of global state are well-documented, but I find dmbarbour's argument that Local state is poison a very interesting alternative way to look at what properties do we want from code; more generally, what kind of compositionalty PLs offer is very much paradigm dependent. Gotos are considered harmful, but the Linux kernel has little trouble with longjmp because of its mandated coding style: compositionality in engineering is a not just a matter of semantics but also of use. He targets OO and Haskell's type classes - I think he is quite correct - note that within these paradigms one can regain compositionality by restricting to LSP or algebraic classes, and supporting his thesis we see that these ideas have spawned ideas for the design of new, cleaner PLs.

Seven Sketches in Compositionality: An Invitation to Applied Category Theory

2018 by Brendan Fong and David I. Spivak

Category theory is becoming a central hub for all of pure mathematics. It is unmatched in its ability to organize and layer abstractions, to find commonalities between structures of all sorts, and to facilitate communication between different mathematical communities. But it has also been branching out into science, informatics, and industry. We believe that it has the potential to be a major cohesive force in the world, building rigorous bridges between disparate worlds, both theoretical and practical. The motto at MIT is mens et manus, Latin for mind and hand. We believe that category theory—and pure math in general—has stayed in the realm of mind for too long; it is ripe to be brought to hand.

An enjoyable 25-minute introductory talk: YOW! Lambda Jam 2019 - Ken Scambler - Applied Category Theory (slides)

What do programming, quantum physics, chemistry, neuroscience, systems biology, natural language parsing, causality, network theory, game theory, dynamical systems and database theory have in common?

As functional programmers, we know how useful category theory can be for our work - or perhaps how abstruse and distant it can seem. What is less well known is that applying category theory to the real world is an exciting field of study that has really taken off in just the last few years. It turns out that we share something big with other fields and industries - we want to make big things out of little things without everything going to hell! The key is compositionality, the central idea of category theory.

Previously: Seven Sketches in Compositionality: An Invitation to Applied Category Theory.

(via Brian McKenna)

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A positionless wonder out of Clemson, Isaiah Simmons has played edge rusher, linebacker, cornerback and safety. He might be the most NFL-ready player in the draft.