owl B&N Unveils 7.8-Inch Nook GlowLight Plus eReader By www.pcmag.com Published On :: A larger screen and waterproof casing are being offered to encourage sales for 'worry-free summer reading.' Will you be willing to pay $199 for it, though? Full Article
owl Barnes & Noble Nook GlowLight Plus (2019) By www.pcmag.com Published On :: Barnes & Noble's Nook GlowLight Plus ebook reader has great hardware for the price, but its software and services are limited and buggy. Full Article
owl 32 Unforgettable Tech Super Bowl Ads By www.pcmag.com Published On :: As game day approaches, watch the best (and worst) Super Bowl tech ads ever aired, and get a preview of what the tech companies that can afford it have in store for 2020. Full Article
owl Town authorities acknowledge spiritual realities By feedproxy.google.com Published On :: Fri, 17 May 2013 13:20:04 +0000 French OMer Andre experiences that prayer can change the hearts of authorities regarding victims of human trafficking. Full Article
owl Armed with knowledge, now less vulnerable By feedproxy.google.com Published On :: Thu, 25 Aug 2016 19:59:09 +0000 One woman’s risk of exploitation decreased when she learnt to read and write through OM's adult literacy programme in Bangladesh. Full Article
owl Strengthening After-School Programs by Building a 'Knowledge Neighborhood' By feedproxy.google.com Published On :: Thu, 14 Dec 2017 00:00:00 +0000 A community-based organization's partnership with researchers creates a 'knowledge neighborhood' supporting after-school programs. Full Article After+school
owl Waterfowl prohibited from Delaware State Fair in avian influenza precaution By news.delaware.gov Published On :: Mon, 22 Jun 2015 12:34:32 +0000 To protect against the spread of avian influenza, the Delaware Department of Agriculture is prohibiting waterfowl entries in the poultry competitions at the Delaware State Fair next month. "This action is being taken out of an abundance of caution to guard against the spread of avian influenza," said Delaware State Veterinarian Dr. Heather Hirst. There have been no East Coast cases of the disease. There are no immediate public health concerns, and poultry and eggs which are properly prepared and cooked are still safe to eat. Full Article Department of Agriculture
owl How to share your SAS knowledge with your professional network By feedproxy.google.com Published On :: Fri, 03 Apr 2020 13:25:34 +0000 SAS Global Forum 2020 is not the conference experience we thought it would be. Thousands of us had planned to gather in person to share our enthusiasm and knowledge about SAS and power of data and analytics. We were going to combine our skills and knowledge to inspire one another [...] The post How to share your SAS knowledge with your professional network appeared first on The SAS Dummy. Full Article Uncategorized github LinkedIn SAS Communities SAS global forum
owl UK acknowledges need for grouping approach to PFASs By chemicalwatch.com Published On :: Thu, 07 May 2020 12:37:00 GMT Junior minister says 'independent' decisions will be based on rigorous scientific assessment Full Article
owl ICC ODI rankings: Virat Kohli continues to dominate batsmen ranking; Jasprit Bumrah loses top spot among bowlers By www.financialexpress.com Published On :: 2020-02-12T19:08:00+05:30 ICC ODI rankings: In the all-rounders' category, Ravindra Jadeja, moved up three places above to be placed at seventh position . Full Article Sports
owl ICC Women’s T20 World Cup: Shafali Verma, bowlers help India beat New Zealand by four runs By www.financialexpress.com Published On :: 2020-02-27T14:22:00+05:30 In the final over, Heyley Jensen (11) and Kerr cracked a four each but Shikha held her nerves in the end to complete the win. Full Article Sports
owl Former Pakistani cricketer warns bowlers against sledging Virat Kohli By www.financialexpress.com Published On :: 2020-04-09T13:45:00+05:30 Earlier, Michael Clarke had said that Australian players who were keen to join the ludicrous Indian Premier League did not want to take on players like Virat Kohli and Rohit Sharma. Full Article Sports
owl To spit or not: Bowlers face ‘saliva’ conundrum in post COVID-19 scenario By www.financialexpress.com Published On :: 2020-04-20T17:04:00+05:30 The world will never be the same even when it is able to overcome the current crisis. In such a scenario, the way the game is played is also likely to change. Full Article Sports
owl Chicken, Egg and Vegetables Rice Bowl By casaveneracion.com Published On :: Thu, 23 Apr 2020 18:05:53 +0000 Chicken, Egg and Vegetables Rice Bowl appeared first on CASA Veneracion To the basic oyakodon recipe, I added snow peas and bell pepper strips to make this delicious and colorful chicken, egg and vegetables rice bowl meal. Why add vegetables? For variety, mainly. Oyakodon-style recipes are one of our go-to dishes. We just change the chicken component from time to time — shrimps are especially good! … Chicken, Egg and Vegetables Rice Bowl was written by Connie Veneracion and originally published in CASA Veneracion. Full Article Chicken Duck & Turkey Chicken Fillets Rice Bowl Meals
owl Sensor-based baby sock Owlet banks $24M Series B By feedproxy.google.com Published On :: 2018-05-14T05:00:00-07:00 Owlet, a connected-baby care company raised a $24 million Series B investment from Trilogy Equity Partners, with participation from existing investors, including Eclipse Ventures, Broadway Angels, and Enfield Ventures, and the addition Pelion Venture Partners. Owlet Android App Owlet’s core product is a baby sock that contains a smart sensor. The sensor monitors pulse oximetry, a technology used in hospitals to measure an infant's heart rate and blood oxygen levels. The vital signs are communicated to parents’ smartphone via Bluetooth connection. The product retails for $299 and parents can also choose from monthly payment plans. Other IoT-health startups using sensors to monitor vital signs include Aifloo, a company selling wrist-bands for elders and Air by Propeller, a smart health company that provides an API to predict local asthma conditions. SM Owlet Smart Sock 2 A complete product package of Owlet monitor includes three fabric socks, smart sock sensor, a base station (which rings an alarm if a baby’s vital signs are abnormal), and charging cords. Before the company raised the latest round, it closed a $15 million Series B round in late 2016. The recent investment brought Owlet’s total equity funding to $46M. Owlet plans to use the growth capital to launch more baby care products. “As a company of parents, it is important to us to bring innovative technology into a family’s everyday life. This new round of funding will enable us to expand our product line, looking at ways we can support the health and wellness of families at all stages, from pregnancy on, as well as increase the brand’s availability internationally and improve our accessibility and affordability,”said Kurt Workman, Owlet Co-Founder and CEO. Full Article
owl Sir William the Goat, referee disputes and the birth of the Iron Bowl: Tales of college football in the spring By www.espn.com Published On :: Fri, 1 May 2020 13:21:48 EST If college football is forced to play in the spring, it won't be the first time that has happened. You just have to go back to the 19th century. Full Article
owl [Men's Basketball] Men's Basketball goes on the Road to Crowley's Ridge By www.haskellathletics.com Published On :: Fri, 24 Jan 2020 11:00:00 -0600 Full Article
owl EDA Retrospective: 30+ Years of Highlights and Lowlights, and What Comes Next By feedproxy.google.com Published On :: Thu, 25 Jun 2015 11:00:00 GMT In 1985, as a relatively new editor at Computer Design magazine, I was asked to go forth and cover a new business called CAE (computer-aided engineering). I knew nothing about it, but I had been writing about design for test, so there seemed to be somewhat of a connection. Little did I know that “CAE” would turn into “EDA” and that I’d write about it for the next 30 years, for Computer Design, EE Times, Cadence, and a few others. Now that I’m about to retire, I’m looking back over those 30 years. What a ride it has been! By the numbers I covered 31 Design Automation Conferences (DACs), hundreds of new products, dozens of acquisitions and startups, dozens of lawsuits, and some blind alleys that didn’t work out (like “silicon compilation”). Chip design went from gate arrays and PLDs with a few thousand gates to processors and SoCs with billions of transistors. In 1985 there were three big CAE vendors – Daisy Systems, Mentor Graphics, and Valid Logic. All sold bundled packages that included workstations and CAE software; in fact, Daisy and Valid designed and manufactured their own workstations. In the early 1980s a workstation with schematic capture and gate-level logic simulation might have set you back $120,000. In 1985 OrCAD, now part of Cadence, came out with a $500 schematic capture package running on IBM PCs. Cadence and Synopsys emerged in the late 1980s, and by the 1990s the EDA industry was pretty much a software-only business (apart from specialized machines like simulation accelerators). Since the early 1990s the “big three” EDA vendors have been Cadence, Synopsys, and Mentor, giving the industry stability but allowing for competition and innovation. Here, in my view, are some of the highlights that occurred during the past 30 years of EDA. EDA is a Highlight The biggest highlight in EDA is the existence of a commercial EDA industry! Marching hand in hand with the fabless semiconductor revolution, commercial EDA made it possible for hundreds of companies to design semiconductors, as opposed to a small handful that could afford large internal CAD operations and fabs. With hundreds of semiconductor companies as opposed to a half-dozen, there’s a lot more creativity, and you get the level of sophistication and intelligence that you see in your smartphone, video camera, tablet, gaming console, and car today. CAE + CAD = EDA. This is not just a terminology issue. By the mid-1980s it became clear that front-end design (CAE) and physical design (CAD) belonged together. The big CAE vendors got involved in IC and PCB CAD, and presented increasingly integrated solutions. People got tired of writing “CAE/CAD” and “EDA” was born. The move from gate-level design to RTL. This move happened around 1990, and in my view this is EDA’s primary technology success story during the past 30 years. Moving up in abstraction made the design and verification of much larger chips possible. Going from gate-level schematics to a hardware description language (HDL) revolutionized logic design and verification. Which would you rather do – draw all the gates that form an adder, or write a few lines of code and let a synthesis tool find an adder in your chosen technology? Two developments made this shift in design possible. One was the emergence of commercial RTL synthesis (or “logic synthesis”) tools from Synopsys and other companies, which happened around 1990. Another was the availability of Verilog, developed by Gateway Design Automation and purchased by Cadence in 1989, as a standard RTL HDL. Although most EDA vendors at the time were pushing VHDL, designers wanted Verilog and that’s what most still use (with SystemVerilog coming on strong in the verification space). IC functional verification underwent huge changes in the late 1990s and early 2000s, largely due to new technology developed by Verisity, which was acquired by Cadence in 2005. Before Verisity, verification engineers were writing and running directed tests in an ad-hoc manner. Verisity introduced or improved technologies such as pseudo-random test generation, coverage metrics, reusable verification IP, and semi-automated verification planning. The Verisity “e” language became a widely used hardware verification language (HVL). The biggest way that EDA has expanded its focus has been through semiconductor IP. Today Synopsys and Cadence are leading providers in this area. Thanks to the availability of design and verification IP, many SoC designs today reuse as much as 80% of previous content. This makes it much, much faster to design the remaining portion. While IP began with fairly simple elements, today commercially available IP can include whole subsystems along with the software that runs on them. With IP, EDA vendors are providing not only design tools but design content. Finally, the EDA industry has done an amazing job of keeping up with SoC complexity and with advanced process nodes. Thanks to intense and early collaboration between foundries, IP, and EDA providers, tools and IP have been ready for process nodes going down to 10nm. Where Does ESL Fit? In some ways, electronic system level (ESL) design is both a lowlight and a highlight. It’s a lowlight because people have been talking about it for 30 years and the acceptance and adoption have come very slowly. ESL is a highlight because it’s finally starting to happen, and its impact on design and verification flows could be dramatic. Still, ESL is vaguely defined and can be used to describe almost anything that happens at a higher abstraction level than RTL. High-level synthesis (HLS) is an ESL technology that is seeing increasing use in production environments. Current HLS tools are not restricted to datapaths, and they produce RTL code that gives better quality of results than hand-written RTL. Another ESL methodology that’s catching on is virtual prototyping, which lets software developers write software pre-silicon using SystemC models. Both HLS and virtual prototyping are made possible by the standardization of SystemC and transaction-level modeling (TLM). However, it’s still not easy to use the same SystemC code for HLS and virtual prototyping. And Now, Some Lowlights Every new industry has some twists and turns, and EDA is no exception. For example, the EDA industry in the 1980s and 1990s sparked a lot of lawsuits. At EE Times my colleagues and I wrote a number of articles about EDA legal disputes, mostly about intellectual property, trade secrets, or patent issues. Over the past decade, fortunately, there have been far fewer EDA lawsuits than we had before the turn of the century. Another issue that was troublesome in the 1980s and 1990s was so-called “standards wars.” These would occur as EDA vendors picked one side or the other in a standards dispute. For example, power intent formats were a point of conflict in the early 2000s, but the Common Power Format (CPF) and the Unified Power Format (UPF) are on the road to convergence today with the IEEE 1801 effort. As mentioned previously, Verilog and VHDL were competing for adoption in the early 1990s. For the most part, Verilog won, showing that the designer community makes the final decision about which standards will be used. How on earth did there get to be something like 30 DFM (design for manufacturability) companies 10-12 years ago? To my knowledge, none of these companies are around today. A few were acquired, but most simply faded away. A lot of investors lost money. Today, VCs and angel investors are funding very few EDA or IP startups. There are fewer EDA startups than there used to be, and that’s too bad, because that’s where a lot of the innovation comes from. Here’s another current lowlight -- not enough bright engineering or computer science students are joining EDA companies. They’re going to Google, Apple, Facebook, and the like. EDA is perceived as a mature industry that is still technically very difficult. We need to bring some excitement back into EDA. Where Is EDA Headed? Now we come to what you might call “headlights” and look at what’s coming. My list includes: System Design Enablement. This term has been coined by Cadence to describe a focus on whole systems or end products including chips, packages, boards, embedded software, and mechanical components. There are far more systems companies than semiconductor companies, leaving a large untapped market that’s looking for solutions. New frontiers for EDA. At a 2015 Design Automation Conference speech, analyst Gary Smith suggested that EDA can move into markets such as embedded software, mechanical CAD, biomedical, optics, and more. Vertical markets. EDA has until now been “horizontal,” providing the same solution for all market segments. Going forward, markets like consumer, automotive, and industrial will have differing needs and will need optimized tools and IP. Internet of Things. This is a current buzzword, but the impact on EDA remains uncertain. Many IoT devices will be heavily analog, use mature process nodes, and be dirt cheap. Lip-Bu Tan, Cadence CEO, recently pointed out that the silicon percentage of IoT revenue will be small and that a lot of the profits will be on the service side. Moving On For the past six years I’ve been writing the Industry Insights blog at Cadence.com. All things change, and with this post comes a farewell – I am retiring in late June and will be pursuing a variety of interests other than EDA. I’ll be watching, though, to see what happens next in this small but vital industry. Thanks for reading! Richard Goering Full Article cadence Richard Goering EDA CAE EDA retrospective EE Times
owl Indian Spooks Snooping Without ISP Knowledge By packetstormsecurity.com Published On :: Mon, 09 Sep 2013 15:11:50 GMT Full Article headline government privacy india spyware
owl The Lowly Coronation of the High King of Heaven () By feeds.gty.org Published On :: Sun, 05 Apr 2020 00:00:00 Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church. Full Article Selected Scriptures
owl Italians slowly venture out into the world again By www.shanghaidaily.com Published On :: Wed, 06 May 2020 00:00:00 +0800 Italians strolled in the park, grabbed take-out cappuccinos and paid their respects to the astonishing number of dead as the European epicenter of the coronavirus pandemic gingerly woke up from the continent’s Full Article World
owl Lawbite:Language, context and background knowledge should not to be disregarded By www.eversheds.com Published On :: 2019-02-11 Ashtead Plant Hire Company Limited v Granton Central Developments Limited [2019] CSOH 7 This case involves a landlord and tenant dispute over the proper construction of the rent review provisions in a lease of commercial premises. The parties ... Full Article
owl Revamped Pacific RISA Website Features Integrated Climate Knowledge for Hawai‘i and Pacific Islands By feedproxy.google.com Published On :: Fri, 30 Nov 2012 02:55:03 +0000 HONOLULU (Nov. 29, 2012) -- The Pacific Regional Integrated Sciences and Assessments program (Pacific RISA) has launched an updated, interactive website as a focal point for the current state of climate knowledge about Hawai‘i and the U.S-Affiliated Pacific Islands. The improved site at PacificRISA.org serves as a hub of interactive media, publications, and tools produced by researchers at the East-West Center, the University of Hawai‘i, and other partner organizations. Users can explore current knowledge about climate change from Pacific RISA’s interdisciplinary work in areas such as climate projections, hydrological modeling, disaster risk assessment, and legal and policy analysis. Full Article
owl Combining sector knowledge and technical know-how to deliver largest unsubsidised wind farm in Europe By www.eversheds.com Published On :: 2020-04-29 Eversheds Sutherland advises Glennmont on the sale of a minority stake in 211MW Finnish wind project Eversheds Sutherland has advised Glennmont Partners on its agreed sale of a 15% minority stake in Project Piiparinmäki, a 211.4MW wind farm, to... Full Article
owl Dowladda Soomaaliya oo sheegtay in si habsami leh uu u socdo barnaamijka baxnaano. By horseedmedia.net Published On :: Fri, 08 May 2020 19:53:38 +0000 Wasiirka Shaqada iyo Arrimaha bulshada ee Xukumadda Federaalka Soomaaliya Sadiiq Xirsi warfaa ayaa sheegay in si habsami leh uu u socdo barnaamijka Baxnaano oo loogu talagalay in lagu kaalmeeyo dadka danyara ah. Wasiirka Warfaa ayaa sheegay in mashruucaan uu yahay mid ay leedahay Dowladda Soomaaliyeed, isla markaana uu taageero ka heysto Bankiga aduunka waxaana bishii […] The post Dowladda Soomaaliya oo sheegtay in si habsami leh uu u socdo barnaamijka baxnaano. appeared first on Horseed Media • Somali News. Full Article Federal Republic of Somalia Somali News
owl Knowledge is everywhere. Here are four ways to make it easier to share. -- by Sonia Chand Sandhu By blogs.adb.org Published On :: Tue, 15 Oct 2019 15:12:00 +0800 A wealth of knowledge – knowhow and wisdom – rests with the officials, professionals, practitioners and communities. The challenge is to unleash the untapped power of this information. Full Article
owl Q&A: How a New Port is Building Skills and Knowledge in Nauru By feedproxy.google.com Published On :: 2020-04-08 00:00:00 Nimitz Adam, 39, from Boe District, is a mechanic at Nauru’s Aiwo Boat Harbor. Since construction began on Nauru's new port in October 2019, the father of 6 says the people of Nauru are beginning to realize their dream of having an efficient, reliable, and climate-resilient international port. “The new port will be like a lifeline for the people of Nauru.” Nimitz Adam, mechanic at Nauru’s Aiwo Boat Harbor Full Article
owl The oceans are very slowly draining into the rock below Earth's crust By www.newscientist.com Published On :: Fri, 24 May 2019 12:56:08 +0000 Ever since the breakup of the supercontinent Pangaea, sea water has been flowing deep into the planet, causing sea levels to fall over millions of years Full Article
owl Eating more slowly and dining with others can boost your health By www.newscientist.com Published On :: Wed, 08 Jan 2020 06:00:00 +0000 From the mealtimes you keep and the speed at which you eat to your choice of dining companions, how you eat has a big impact on your health and waistline Full Article
owl Knowledge Is Power for Patients With Heart Failure By www.medicinenet.com Published On :: Sat, 9 May 2020 00:00:00 PDT Title: Knowledge Is Power for Patients With Heart FailureCategory: Health NewsCreated: 4/29/2015 12:00:00 AMLast Editorial Review: 4/30/2015 12:00:00 AM Full Article
owl Too Much Super Bowl Can Mean Too Little Sleep By www.medicinenet.com Published On :: Fri, 31 Jan 2020 00:00:00 PDT Title: Too Much Super Bowl Can Mean Too Little SleepCategory: Health NewsCreated: 1/31/2020 12:00:00 AMLast Editorial Review: 1/31/2020 12:00:00 AM Full Article
owl Knowledge, Attitudes and Practices of Dental Hygienists Regarding Diabetes Risk Assessments and Screenings By jdh.adha.org Published On :: 2020-04-30T12:39:03-07:00 Purpose: Untreated and poorly controlled diabetes causes increased levels of blood glucose associated with poor periodontal disease outcomes. Dental hygienists can play a significant role in screening patients for diabetes mellitus, leading to referral and early diagnosis. The purpose of this study was to determine the knowledge, attitudes, practices, and barriers faced by clinical dental hygienists regarding diabetes risk assessment and screenings.Methods: A mixed method design was used with a convenience sample of dental hygienists in clinical practice (n=316). A 32 item, electronic survey was validated at item-level, and participants were recruited through multiple dental hygiene Facebook groups. Descriptive statistics were used to analyze the data. The survey also included two open-ended attitude questions that were interpreted using thematic analysis to pinpoint common patterns within the data.Results: Dental hygienists had high knowledge scores regarding diabetes and oral health, although many were unaware of their states' specific statutes and regulations for screening practices. Nearly all (95.9%), were likely to educate and refer patients (82%), although fewer than half (40.9%), were likely to perform chairside screening for diabetes. Emergent themes for barriers to screening were time, money, patient acceptance/willingness, lack of education, not having the proper tools, and states' rules and regulations.Conclusion: Despite high knowledge scores regarding diabetes and oral health, there is a gap in regards to dental hygienists' willingness to perform diabetes screenings in a clinical setting. Dental hygienists should be capable of integrating chairside diabetes screening practices into the process of care with proper training. Full Article
owl Acknowledgment of Invited Editors By mbio.asm.org Published On :: 2020-03-24T01:31:01-07:00 Full Article
owl Acknowledgment of Reviewers By mbio.asm.org Published On :: 2020-03-24T01:31:01-07:00 Full Article
owl Minnesota association acknowledges states ancestral lands, residents By thenationshealth.aphapublications.org Published On :: 2020-05-01T05:00:17-07:00 In a nod to the people who came before them — and those who still live among them — the Minnesota Public Health Association is acknowledging ancestral lands. Full Article
owl Reply to Bowling: How specific emotions are primary in subjective experience [Social Sciences] By www.pnas.org Published On :: 2020-05-05T10:31:24-07:00 Our study in PNAS (1) applies a mathematically based framework to the study of reported emotional experience evoked by music in the United States and China. Germane to theoretical debate, our methods reveal how specific emotions such as “triumph” are more primary across cultures than valence and arousal, a finding... Full Article
owl Lithological and chemostratigraphic discrimination of facies within the Bowland Shale Formation within the Craven and Edale basins, UK By pg.lyellcollection.org Published On :: 2020-05-01T00:30:41-07:00 The Carboniferous Bowland Shale Formation of the UK is a proven hydrocarbon source rock and currently a target for shale gas exploration. Most existing analysis details lithofacies and geochemical assessment of a small number of boreholes. Given a paucity of relevant borehole cores, surface samples provide a valuable contribution to the assessment of this unconventional gas source. This study reviews existing literature on the formation's hydrocarbon geochemistry and provides new lithological descriptions of seven lithofacies, XRD mineralogy and hydrocarbon-specific geochemical data for 32 outcrop localities within the Craven and Edale basins, respectively in the northern and southern parts of the resource area. Low oxygen indices suggest that the majority of samples are relatively unaltered (in terms of hydrocarbon geochemistry), and therefore suitable for the characterization of the shale organic character. Total organic carbon (TOC) ranges from 0.7 to 6.5 wt%, with highest values associated with maximum flooding surfaces. Mean Tmax values of 447 and 441°C for the Edale and Craven basins, respectively, suggest that nearly all the samples were too immature to have generated appreciable amounts of dry gas. The oil saturation index is consistently below the >100 mg g–1 TOC benchmark, suggesting that they are not prospective for shale oil. Supplementary material: A table summarizing the location, geological description and age of all of the samples in this paper is available at https://doi.org/10.6084/m9.figshare.c.4444589 Full Article
owl Acknowledgment of Ad Hoc Reviewers [Editorial] By cvi.asm.org Published On :: 2017-12-05T08:00:30-08:00 Full Article
owl Rapid acquisition through fast mapping: stable memory over time and role of prior knowledge [RESEARCH] By learnmem.cshlp.org Published On :: 2020-04-15T06:30:12-07:00 In recent years, there have been intensive debates on whether healthy adults acquire new word knowledge through fast mapping (FM) by a different mechanism from explicit encoding (EE). In this study, we focused on this issue and investigated to what extent retention interval, prior knowledge (PK), and lure type modulated memory after FM and EE. Healthy young participants were asked to learn novel word-picture associations through both FM and EE. Half of the pictures were from familiar categories (i.e., high PK) and the other half were from unfamiliar categories (i.e., low PK). After 10 min and 1 wk, the participants were tested by forced-choice (FC) tasks, with lures from different categories (Experiment 1) or from the same categories of the target pictures (Experiment 2). Pseudowords were used to denote names of the novel pictures and baseline performance was controlled for each task. The results showed that in both Experiments 1 and 2, memory performance remained stable after FM, while it declined after EE from 10 min to 1 wk. Moreover, the effect of PK appeared at 10 min after FM while at 1 wk after EE in Experiment 2. PK enhanced memory of word-picture associations when the lures were from the same categories (Experiment 2), rather than from different categories (Experiment 1). These results were largely confirmed in Experiment 3 when encoding condition was manipulated as a between-subjects factor, while lure type as a within-subjects factor. The findings suggest that different from EE, FM facilitates rapid acquisition and consolidation of word-picture knowledge, and highlight that PK plays an important role in this process by enhancing access to detailed information. Full Article
owl Novel Endochin-Like Quinolones Exhibit Potent In Vitro Activity against Plasmodium knowlesi but Do Not Synergize with Proguanil [Susceptibility] By aac.asm.org Published On :: 2020-04-21T08:01:10-07:00 Quinolones, such as the antimalarial atovaquone, are inhibitors of the malarial mitochondrial cytochrome bc1 complex, a target critical to the survival of both liver- and blood-stage parasites, making these drugs useful as both prophylaxis and treatment. Recently, several derivatives of endochin have been optimized to produce novel quinolones that are active in vitro and in animal models. While these quinolones exhibit potent ex vivo activity against Plasmodium falciparum and Plasmodium vivax, their activity against the zoonotic agent Plasmodium knowlesi is unknown. We screened several of these novel endochin-like quinolones (ELQs) for their activity against P. knowlesi in vitro and compared this with their activity against P. falciparum tested under identical conditions. We demonstrated that ELQs are potent against P. knowlesi (50% effective concentration, <117 nM) and equally effective against P. falciparum. We then screened selected quinolones and partner drugs using a longer exposure (2.5 life cycles) and found that proguanil is 10-fold less potent against P. knowlesi than P. falciparum, while the quinolones demonstrate similar potency. Finally, we used isobologram analysis to compare combinations of the ELQs with either proguanil or atovaquone. We show that all quinolone combinations with proguanil are synergistic against P. falciparum. However, against P. knowlesi, no evidence of synergy between proguanil and the quinolones was found. Importantly, the combination of the novel quinolone ELQ-300 with atovaquone was synergistic against both species. Our data identify potentially important species differences in proguanil susceptibility and in the interaction of proguanil with quinolones and support the ongoing development of novel quinolones as potent antimalarials that target multiple species. Full Article
owl Co-occurrence of Plasmid-Mediated Tigecycline and Carbapenem Resistance in Acinetobacter spp. from Waterfowls and Their Neighboring Environment [Epidemiology and Surveillance] By aac.asm.org Published On :: 2020-04-21T08:01:10-07:00 Tigecycline serves as one of the antibiotics of last resort to treat multidrug-resistant (including carbapenem-resistant) pathogens. However, the recently emerged plasmid-mediated tigecycline resistance mechanism, Tet(X), challenges the clinical efficacy of this class of antibiotics. In this study, we detected 180 tet(X)-harboring Acinetobacter isolates (8.9%, n = 180) from 2,018 samples collected from avian farms and adjacent environments in China. Eighteen tet(X)-harboring isolates (10.0%) were found to cocarry the carbapenemase gene blaNDM-1, mostly from waterfowl samples (94.4%, 17/18). Interestingly, among six Acinetobacter strains, tet(X) and blaNDM-1 were found to colocalize on the same plasmids. Moreover, whole-genome sequencing (WGS) revealed a novel orthologue of tet(X) in the six isolates coharboring tet(X) and blaNDM-1. Inverse PCR suggested that the two tet(X) genes form a single transposable unit and may be cotransferred. Sequence comparison between six tet(X)- and blaNDM-1-coharboring plasmids showed that they shared a highly homologous plasmid backbone even though they were isolated from different Acinetobacter species (three from Acinetobacter indicus, two from Acinetobacter schindleri, and one from Acinetobacter lwoffii) from various sources and from different geological regions, suggesting the horizontal genetic transfer of a common tet(X)- and blaNDM-1-coharboring plasmid among Acinetobacter species in China. Emergence and spread of such plasmids and strains are of great clinical concern, and measures must be implemented to avoid their dissemination. Full Article
owl Screen to Save: Results from NCI's Colorectal Cancer Outreach and Screening Initiative to Promote Awareness and Knowledge of Colorectal Cancer in Racial/Ethnic and Rural Populations By cebp.aacrjournals.org Published On :: 2020-05-01T00:05:36-07:00 Background: The Center to Reduce Cancer Health Disparities (CRCHD), NCI, implemented Screen to Save, NCI's Colorectal Cancer Outreach and Screening Initiative to promote awareness and knowledge of colorectal cancer in racial/ethnic and rural populations. Methods: The initiative was implemented through CRCHD's National Outreach Network (NON). NON is a national network of Community Health Educators (CHE), aligned with NCI-designated Cancer Centers across the nation. In phases I and II, the CHEs focused on the dissemination of cancer-related information and implementation of evidence-based educational outreach. Results: In total, 3,183 pre/post surveys were obtained from male and female participants, ages 50 to 74 years, during the 347 educational events held in phase I. Results demonstrated all racial/ethnic groups had an increase in colorectal cancer–related knowledge, and each group strongly agreed that the educational event increased the likelihood that they would engage in colorectal cancer–related healthful behaviors (e.g., obtain colorectal cancer screening and increase physical activity). For phase II, Connections to Care, event participants were linked to screening. Eighty-two percent of the participants who obtained colorectal cancer screening during the 3-month follow-up period obtained their screening results. Conclusions: These results suggest that culturally tailored, standardized educational messaging and data collection tools are key change agents that can serve to inform the effectiveness of educational outreach to advance awareness and knowledge of colorectal cancer. Impact: Future initiatives should focus on large-scale national efforts to elucidate effective models of connections to care, related to colorectal cancer screening, follow-up, and treatments that are modifiable to meet community needs. Full Article
owl RPGCast – Episode 418: “Zelda Let’s Go Bowling” By feedproxy.google.com Published On :: Sat, 18 Mar 2017 19:21:06 +0000 I’ll be honest with you. I’m pretty sick and I don’t remember what happened on this episode. I think I eventually complained about Mass Effect... Full Article News Podcasts RPG Cast
owl RPG Cast – Episode 532: “Meowls” By feedproxy.google.com Published On :: Sat, 15 Feb 2020 21:16:06 +0000 Anna Marie is finally back (and a little loopy on painkillers). There’s ample fawning for Mass Effect in our Now Playing, as Kelley chooses an unusual romantic encounter! Arguments break out over March and April’s packed release schedule, but a truce is eventually reached. Full Article News Podcasts RPG Cast Dragon Ball Z: Kakarot Final Fantasy IV Fire Emblem: Three Houses Mass Effect Stell Glow The Dark Crystal: Age of Resistance Tactics The Legend of Heroes: Trails of Cold Steel III
owl Taylor Swift Returns to Stage for Pre-Super Bowl Show By blogs.wsj.com Published On :: Sun, 05 Feb 2017 09:16:38 +0000 “Hi, I’m Taylor.” With that greeting, Taylor Swift returned to the stage as the headliner of “DirectTV Now Super Saturday Night” at Club Nomadic on the eve of the Super Bowl. Full Article Celebrity Music Super Bowl Taylor Swift
owl To Silence Wind Turbines and Airplanes, Engineers Are Studying Owl Wings By www.smithsonianmag.com Published On :: Wed, 15 Apr 2020 13:00:00 +0000 No one knows exactly how the nocturnal hunters manage their whisper-soft flight, yet it's inspiring the design of quieter airplanes, fans and wind turbines Full Article
owl Woman being treated for coronavirus symptoms 'spat at and threw contents of sick bowl over nurse' By www.standard.co.uk Published On :: 2020-04-20T19:16:00Z A woman allegedly spat at and threw the contents of a sick bowl over a nurse while being treated for Covid-19 symptoms. Full Article
owl 'Did they introduce me? Am I on?' Joe Biden's 'virtual rally' was virtually unwatchable (here are the lowlights) By twitchy.com Published On :: Fri, 08 May 2020 10:51:04 Z Full Article <![CDATA[Joe Biden]]> <![CDATA[2020 election]]>
owl As people disappear under lockdown, goats, rats and coyotes prowl the streets By www.independent.co.uk Published On :: 2020-04-22T14:30:23Z Humans can easily forget that the cities and towns they call home and frequently visit are also home to wild animals, writes Sandra E Garcia. In Wales, goats roam the streets, while in San Francisco the Coyotes have come out Full Article
owl Uber sees ride bookings recovering slowly, pins hopes on food delivery demand By globalnews.ca Published On :: Thu, 07 May 2020 23:54:38 +0000 Uber on Wednesday said it would lay off 3,700 full-time employees, or roughly 17 per cent of its head count. Full Article Consumer Economy News Tech coornavirus ride share impact Coronavirus coronavirus lyft coronavirus uber app COVID-19 covid-19 uber Dara Khosrowshahi Lyft quber eats ride share apps Ride sharing Ridesharing Uber uber Dara Khosrowshahi uber eats