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Taming Siachen’s raging waters

Making a world record for first ever rafting expedition in the Siachen Glacier, Madurai man Captain K.R.C. Pratap shares his experience of rafting through the Nubra and Shyok rivers.




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Train to Busan: an engaging thriller

A group of people are travelling to Busan in a train. So are zombies.




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‘Mem Famous’ movie review: Sumanth Prabhas makes a promising debut in this partially engaging coming-of-age story

Newcomers led by Sumanth Prabhas get the carefree rural Telangana vibe right in the Telugu film ‘Mem Famous’, which shines in a few segments but falls short of being a roller coaster fun ride




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Man held for damaging idol at temple in Shamshabad




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Morphological analysis of Pd/C nanoparticles using SEM imaging and advanced deep learning

RSC Adv., 2024, 14,35172-35183
DOI: 10.1039/D4RA06113F, Paper
Open Access
Nguyen Duc Thuan, Hoang Manh Cuong, Nguyen Hoang Nam, Nguyen Thi Lan Huong, Hoang Si Hong
In this study, we present a comprehensive approach for the morphological analysis of palladium on carbon (Pd/C) nanoparticles utilizing scanning electron microscopy (SEM) imaging and advanced deep learning techniques.
The content of this RSS Feed (c) The Royal Society of Chemistry




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N-doped carbon quantum dots for the selective detection of OCl− ions, bioimaging, and the production of Fe3O4 nanoparticles utilized in the synthesis of substituted imidazole

RSC Adv., 2024, 14,35448-35459
DOI: 10.1039/D4RA06474G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Namrata Priyadarshini Hota, Sathiyanarayanan Kulathu Iyer
Nitrogen-doped quantum dots (NCQD) were synthesized by solvothermal means using o-phenylenediamine and L-tartaric acid.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Solution-focused brief therapy with clients managing trauma [electronic resource] / Adam Froerer, Jacqui von Cziffra-Bergs, Johnny Kim, Elliott Connie.

New York, NY : Oxford University Press , 2018.




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Water-induced spinodal decomposition of mixed halide perovskite captured by real-time liquid TEM imaging

Energy Environ. Sci., 2024, 17,8745-8755
DOI: 10.1039/D4EE03381G, Paper
Nicolas Folastre, Mohammad Ali Akhavan Kazemi, Kirill Cherednichneko, Arash Jamali, Jean Rousset, Frédéric Sauvage, Arnaud Demortière
Segmented images showing the live degradation of CsMAFA particles in contact with water molecules. The formed particles are CsPb2Br5 and PbI2 resulting from the spinodal decomposition of perovskite before dissolution/recrystallization process.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Specific vegetable types are associated with lower long-term risk for late-life dementia: the Perth Longitudinal Study of Aging Women

Food Funct., 2024, 15,10885-10895
DOI: 10.1039/D4FO03239J, Paper
Negar Ghasemifard, Simone Radavelli-Bagatini, Simon M. Laws, Helen Macpherson, Emma Stevenson, Jonathan M. Hodgson, Richard L. Prince, Joshua R. Lewis, Marc Sim
This study found an association between total vegetable intake as well as specific types of vegetables including yellow/orange/red, green leafy, and allium vegetables with lower long-term risk for late-life dementia in older women.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Inhibitory effect of tea flower polysaccharides on oxidative stress and microglial oxidative damage in aging mice by regulating gut microbiota

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03484H, Paper
Yidan Cai, Siyu Liu, Xing Ge, Lu Cheng, Xin Zhang
Tea flower polysaccharides (TFPS) can improve the disorder of gut microbiota, alleviate oxidative damage to glial cells, alleviate neuroinflammation, and play a role in delaying aging.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ergothioneine improves cognitive function by ameliorating mitochondrial damage and decreasing neuroinflammation in a D-galactose-induced aging model

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO02321H, Paper
Fangyang Chen, Botao Wang, Xin Sun, Yage Wang, Ruiyan Wang, Kaikai Li
EGT intervention significantly improved D-galactose induced oxidative stress, neuroinflammation, and mitochondrial function, resulting in the alleviation of memory injury.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




aging

The Rohini Godbole way of teaching, talking and engaging with students

Remembering the life and legacy of pioneering physicist Professor Rohini Godbole through the eyes of colleagues and students.




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Correction: Ce6-Conjugated and polydopamine-coated gold nanostars with enhanced photoacoustic imaging and photothermal/photodynamic therapy to inhibit lung metastasis of breast cancer

Nanoscale, 2024, 16,20354-20355
DOI: 10.1039/D4NR90194K, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ziwei Li, Fan Yang, Di Wu, Yanhong Liu, Yang Gao, Haichen Lian, Hongxin Zhang, Zhibin Yin, Aiguo Wu, Leyong Zeng
The content of this RSS Feed (c) The Royal Society of Chemistry




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Applications of nanotheranostics in the second near-infrared window in bioimaging and cancer treatment

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03058C, Review Article
Huimin Li, Pengju Li, Jiarui Zhang, Ziyi Lin, Lintao Bai, Heyun Shen
This review summarized the application of the second near-infrared nano-platform in the field of nano-agents design, optical imaging and cancer treatment, aiming at providing profound insights into its development status and future challenges.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




aging

Tailored peptide nanomaterials for receptor targeted prostate cancer imaging

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03273J, Paper
Fátima Santillán, Carlie L. Charron, Betty C. Galarreta, Leonard G. Luyt
This study reports on a cancer targeted nanomaterial created from cyclic octapeptides that is tailored for the optical imaging of prostate cancer. The strategy focuses on the co-assembly of four specific templates into cyclic peptide nanotubes.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




aging

Aptamer-functionalized Nucleic Acid Nanotechnology for Biosensing, Bioimaging and Cancer Therapy

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR04360J, Review Article
Xiaofang Zheng, Zhiyong Huang, Qiang Zhang, Guoli Li, Minghui Song, Ruizi Peng
Nucleic acids have enabled to fabricate self-assemblies and perform dynamic operations. Among different functional nucleic acids, aptamers can specifically bind to wide range of targets including proteins, viral antigens, living...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Endocrinology plays a vital role in diagnosing, managing and preventing lifestyle disorders like diabetes and thyroid, says Venkaiah Naidu




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Maize research body seeks funding to undertake research on managing aflatoxin in DDGS

IIMR says various technologies can be used to reduce the aflatoxin




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Solid body wash comes without packaging. But does that make it eco-friendly?

Cosmetics firms appeal to plastic-free consumers with the hybrid of bar soap and liquid body wash




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AkzoNobel, Thomas Swan to develop coatings for metal packaging




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Calico and AbbVie advance antiaging efforts




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Maharashtra Assembly elections: Human-leopard conflict to be a raging issue in 4 seats of Pune district







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Here's how NASA engineers piloting the Mars rover are managing their work-life balance during lockdown

  • NASA engineers are continuing to drive the Mars Curiosity Rover while working from home.
  • The job is highly technical and delicate, but the team has already managed to complete a successful operation under lockdown.
  • Business Insider asked two of the rover team how they manage their work-life balance now the rover has colonised their living space.
  • Visit Business Insider's homepage for more stories.

Life during lockdown has meant millions of people having to adapt to their home and work lives colliding. But what's that like when your work involves driving a nuclear-powered robot on the surface of Mars?

Business Insider spoke to two of the NASA technicians currently piloting the Mars Curiosity rover from home. It's a delicate operation that takes careful planning between a team of roughly 75 NASA engineers and scientists. Even while working remotely, the team was able to rig up their home workstations well enough that the rover has already completed a successful drilling operation while its human operators are in lockdown.

Despite doing the most otherworldly job imaginable, the Curiosity rovers are having to contend with familiar stresses of lockdown working life. They told Business Insider their personal tips and tricks for staying focused and healthy as they work from home.

Get comfy

Matt Gildner is the planning team lead for the rover, which means he directs a team of about 20 people who build the commands to send the rover to tell it where to go and what to do. Gildner's day involves staying permanently teleconferenced in to conversations using two headsets, one in each ear. A few times a day he also uses red-blue 3D glasses to examine images sent back by the rover.

His first change to his work-from-home set-up: Get a better chair. "The first week I got here I had an old wooden bank chair that while it looked really nice next to my desk, [was] not very comfortable," said Gildner. He quickly swapped this out for a more comfortable ergonomic chair. He and his wife are also making cold-brew coffee every night, ready to go in the morning.

Make sure you're seeing some kind of change

Gildner's also trying to make sure he doesn't stay glued to his ergonomic chair, making it a point to get up and moving around. "It's really about just getting up and stepping away from the desk for a while," Gildner said. This could be to just go to the kitchen to get a snack or, in Gildner's case, tend to some home baking projects.

"I was already baking some bread before this all happened, but I did kind of up my game in that area," he said. Specifically Gildner (a fan of the YouTube cooking channel "Bon Appetit") has started experimenting with overnight dough fermentation.

"It's nice to go and have something new to see every morning that changed overnight, or you get to see something progress," he said. "That's an important part of mental health and this point in time — to make sure you are having something in your life that is life-changing and dynamic despite your being in the same place."

He draws a parallel between this and his work on the rover. "That is one of the big draws of working a spacecraft operation, especially on Mars, is that every day we're driving to a new place and I get to look at images that no human has ever seen before. And Mars is always throwing us something new."

Keep a firm line between work time and downtime

"I also tend to really shut my computer down and put my phone away for work at the end of the day, just because I want to still try to keep some good separation between work life and home life, even though they're happening in the same place right now," Gildner said.

Project lead Alicia Allbaugh, who oversees the entire team of 75, also likes to draw a clear line between home and work life. She also recommends "not blending home tasks during your work time."

"I try not to deviate too much from what I would've done at work. Because then it can get you distracted and you start pulling away," she said.

Allbaugh also had to divvy up parts of the house with her husband, who also works at NASA. The two didn't want to work in adjacent rooms because they might hear each other's teleconferences through the walls, so Allbaugh works upstairs while her husband gets the kitchen, along with the couple's two rescue bunnies Oreo and Grayce.

In her free time Allbaugh has been tinkering with home improvements, and finished a long-standing project of painting and varnishing some linen-closet doors.

Respect other people's rhythms

As manager of a large team, Allbaugh also has to be sensitive to the fact that everyone has different daily rhythms working from home, especially those with children. Sudden mutes in meetings for children talking and clocks chiming have become the norm.

"We're all very empathetic for each other. I mean we find this adorable. We're not frustrated, whereas if someone came in and interrupted your meeting when you were in the conference room, you may have been like, 'What was that about?'" said Allbaugh.

Keep up the social side of the office

Allbaugh's team has also tried to keep social elements of their office going through virtual happy hours, and she has set up open-office tea break meetings so her team can just come in for a chat, which she thinks is important to keep up even as the lockdown drags on. "Because at first it's novel, and then it's okay — now it's a marathon," she said.  

SEE ALSO: NASA engineers explain what it's like to drive a nuclear-powered Mars rover from home during the pandemic

Join the conversation about this story »

NOW WATCH: A cleaning expert reveals her 3-step method for cleaning your entire home quickly




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Managing the Emergence of Rising Powers: A Western Response

Research Event

22 May 2014 - 5:00pm to 6:15pm

Chatham House, London

Event participants

Trine Flockhart, Senior Fellow, Transatlantic Academy
Patrick W Quirk, Fellow, Transatlantic Academy
Chair: Dr Leslie Vinjamuri, Senior Lecturer in International Relations, SOAS

This event will present the findings of the Transatlantic Academy’s new report, Liberal Order in a Post-Western World, which examines the future of international liberal order in a world shaped by the rise of emerging powers and a transatlantic community dealing with internal challenges. Produced by collaboration between scholars from Europe and North America, it recommends ways to build an enduring rules-based order for the 21st century.

Department/project




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Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of {alpha}-crystallin: Implications for lens aging and presbyopia [Glycobiology and Extracellular Matrices]

Lens proteins become increasingly cross-linked through nondisulfide linkages during aging and cataract formation. One mechanism that has been implicated in this cross-linking is glycation through formation of advanced glycation end products (AGEs). Here, we found an age-associated increase in stiffness in human lenses that was directly correlated with levels of protein–cross-linking AGEs. α-Crystallin in the lens binds to other proteins and prevents their denaturation and aggregation through its chaperone-like activity. Using a FRET-based assay, we examined the stability of the αA-crystallin–γD-crystallin complex for up to 12 days and observed that this complex is stable in PBS and upon incubation with human lens–epithelial cell lysate or lens homogenate. Addition of 2 mm ATP to the lysate or homogenate did not decrease the stability of the complex. We also generated complexes of human αA-crystallin or αB-crystallin with alcohol dehydrogenase or citrate synthase by applying thermal stress. Upon glycation under physiological conditions, the chaperone–client complexes underwent greater extents of cross-linking than did uncomplexed protein mixtures. LC-MS/MS analyses revealed that the levels of cross-linking AGEs were significantly higher in the glycated chaperone–client complexes than in glycated but uncomplexed protein mixtures. Mouse lenses subjected to thermal stress followed by glycation lost resilience more extensively than lenses subjected to thermal stress or glycation alone, and this loss was accompanied by higher protein cross-linking and higher cross-linking AGE levels. These results uncover a protein cross-linking mechanism in the lens and suggest that AGE-mediated cross-linking of α-crystallin–client complexes could contribute to lens aging and presbyopia.




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Re: Prognosis of unrecognised myocardial infarction determined by electrocardiography or cardiac magnetic resonance imaging: systematic review and meta-analysis




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Developing a Road Map for Engaging Diasporas in Development: A Handbook for Policymakers and Practitioners in Home and Host Countries

This practical handbook highlights policies and programs that can magnify the resources, both human and financial, that emigrants and their descendants contribute to development. It gives concrete examples of policies and programs that have been effective, and pulls out both useful lessons and common challenges associated with the topics at hand.




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Managing Borders in an Increasingly Borderless World

This edited volume showcases approaches toward border management in Europe, Central America, and North America, and reflects on the challenges that countries in these regions face in managing their borders. The book brings together perspectives from both sides of the Atlantic on what border security means in practice, the challenges that continue to evade policymakers, and what policies have been the most (and least) successful in achieving “secure” borders.




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Live imaging of synapse density in the human brain

A new imaging technique may give researchers fresh insights into brain development, function, and disease

The human brain is often said to be the most complex object in the known universe, and there’s good reason to believe that it is. That lump of jelly inside your head contains at least 80 billion nerve cells, or neurons, and even more of the non-neuronal cells called glia. Between them, they form hundreds of trillions of precise synaptic connections; but they all have moveable parts, and these connections can change. Neurons can extend and retract their delicate fibres; some types of glial cells can crawl through the brain; and neurons and glia routinely work together to create new connections and eliminate old ones.

These processes begin before we are born, and occur until we die, making the brain a highly dynamic organ that undergoes continuous change throughout life. At any given moment, many millions of them are being modified in one way or another, to reshape the brain’s circuitry in response to our daily experiences. Researchers at Yale University have now developed an imaging technique that enables them to visualise the density of synapses in the living human brain, and offers a promising new way of studying how the organ develops and functions, and also how it deteriorates in various neurological and psychiatric conditions.

Related: Brain’s immune cells hyperactive in schizophrenia

Related: 3D model of a nerve terminal in atomic detail | Mo Costandi

Continue reading...




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Encouraging smaller churches in Russia

Dorothea, from Germany, joins the one-year programme with OM Russia, which includes visiting Siberian villages to help churches and sharing the Gospel with locals.




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Living and engaging in a Muslim community

After discovering his freedom in Christ and being discipled, former drug addict Ruslan wants to share hope with the least reached.




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Encouraging local believers

OM Riverboat community members encourage local believers who are struggling with their faith.




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Mahesh Babu Appointed Managing Director And CEO, Mahindra Electric

Mahesh has been with Mahindras for over 20 years and has worked in design and development of engine and vehicle platforms from frugal 3-wheelers to flagship models.




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Investors have already started changing their strategy: Bhaskar Majumdar, Managing Partner, Unicorn India Ventures

Cash flows will be tight and they may also experience delay in the investment cycle, but this is a temporary phase, says Bhaskar Majumdar, managing partner, Unicorn India Ventures (UIV), a Mumbai-based fund house.




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Instagram Live: Make your ‘Live’ totally engaging

Instagram Live allows users to stream video to followers and engage with them in real time. Here are some cool tips to make your quarantine a little more interesting.




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How messaging app Reliance JioChat makes a mark; check out the top 6 features

A key feature is the peer-to-peer money transfer facility within the app.




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Marketing Is Aging Like a Fine Wine [Infographic]

The discipline is projected to mature into a rich blend of social media and mobile engagement.




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Managing the Risks of Renewable Energy Projects in Developing Countries

Driven by rapid expansion in developing countries, renewables are becoming a significant source of the world’s power.  According to the United Nations Environmental Programme’s (UNEP) 9th “Global Trends in Renewable Energy Investment 2015,” investment in developing countries was up 36 percent in 2014, totaling $131.3 billion.




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Packaging with a view….prize!

The text version of this document in not available. You can...




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Chill wind of pandemic ravaging economies everywhere

More and more indicators are spelling out the scale of economic damage being wreaked by Covid-19 and the containment measures taken to tackle it, writes Robert Shortt.



  • Analysis and Comment


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Game based learning camouflaging fun with learning

Organisations of the modern era require proper and effective training materials which carry the potential to enhance the skills and knowledge of employees. Proper training systems can...




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Canada: Leveraging Training and Skills Development in SMEs - An analysis of two urban regions Montreal and Winnipeg

This paper looks at a study carried out among 80 small and medium sized enterprises (SMEs) in two Canadian cities, Montréal and Winnipeg, based on a survey and case studies, which show the importance of innovation among Canadian SMEs. These innovations in turn create new demands for skill development, both through formal training and in informal activities.




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OSAA-OECD high-level event on leveraging pension funds for financing infrastructure development in Africa

Addis Ababa - Part of the 3rd International Conference on Financing for Development, this event explored strategies to leverage Africa’s pension funds and other sources of private financing to develop Africa’s infrastructure. Ways to improve the investment climate in Africa using the recently updated Policy Framework for Investment were also be addressed.




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Financial system risk is elevated and global standards are essential in managing cross-border infrastructure investment

A new OECD report, the 2018 Business and Finance Outlook, highlights a number of major risks having the potential to disrupt global economic growth. It notes that the gradual normalisation of monetary policy in an environment of growing debt will be a major test of whether the Basel III regulatory reforms have achieved their goal of ensuring safety and soundness in the financial system.




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Cybersecurity: Managing risks for greater opportunities

While the nature of cyber attacks continues to include criminal activities motivated by financial gain, the main emerging threats are large-scale denial of service attacks, information leaks, targeted cyber espionage, and the disruption of critical infrastructures.




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OSAA-OECD high-level event on leveraging pension funds for financing infrastructure development in Africa

Addis Ababa - Part of the 3rd International Conference on Financing for Development, this event explored strategies to leverage Africa’s pension funds and other sources of private financing to develop Africa’s infrastructure. Ways to improve the investment climate in Africa using the recently updated Policy Framework for Investment were also be addressed.