Misfit Addiction Counseling is Colorado's Leader in Teletherapy

As one of the top five most popular shopping destinations in the U.S., Orlando is a shoppers paradise. And the I-Drive area is well-known for its designer outlets and great bargains.

How do you know when to settle a workers’ compensation case? How do you know if you should settle the case, or if you should litigate the case? As…

Clear Seas Research conducted a study on behalf of Quality in order to look at trends in compensation, work hours, and job constraints; overall job satisfaction; and quality improvements, as well as provide a demographic profile of industry professionals. How does your work compare?

Looks like an even better deal SPECIFICALLY for Amazon Prime members than the one on offer in May 2024 (https://www.ozbargain.com.au/node/848019).

https://www.amazon.com.au/dp/B0D2HDV8T9

Have to be logged in to Amazon Prime account to see the $539.98 pricing.

La repostería cobra especial importancia en esta época del año Leer

El arroz de la casa, las migas o el lomo en manteca, entre los platos más pedidos de la carta Leer

A new survey found that TSP participant satisfaction is at 84%, a 2% increase over last year’s results from the Federal Retirement Thrift Investment Board.

The post TSP participant satisfaction rebounds slightly in 2024 survey first appeared on Federal News Network.

Location: Electronic Resource- 

Location: Electronic Resource- 

Escuche el programa de este viernes 25 octubre. La Luciérnaga, un espacio de humor y opinión de Caracol Radio que desde hace 31 años acompaña a sus oyentes en su regreso casa.

Escuche el programa de este jueves 31 de octubre. La Luciérnaga, un espacio de humor y opinión de Caracol Radio que desde hace 31 años acompaña a sus oyentes en su regreso casa.

El artista Gilberto Santa Rosa se encuentra en Colombia en una gira de conciertos.

En Caracol Radio estuvo Lesly Morales, la heredera de las marimondas e hija de César Paraguita,

David Mackalister Silva, capitán de Millonarios, destacó el buen presente del equipo azul tanto en la Liga como en la Copa Sudamericana, compartiendo el liderato en ambos torneos. El volante bogotano se refirió a Medellín y Peñarol, próximos rivales en cada certamen, y habló de las particulares celebracines del equipo.

Álvaro Montero, portero de Millonarios, habló de su actualidad en el cuadro bogotano, luego de haber sido la figura del equipo en la victoria 1-0 sobre el Boyacá Chicó. El guardameta guajiro aprovechó los micrófonos de El Alargue de Caracol Radio para expresar su satisfacción y deseo de poder continuar en el club por más años.

Daniel Cataño, una de las principales figuras de Millonarios en el presente campeonato, expresó sus sensaciones respecto a la final ante Atlético Nacional. En diálogo con El Alargue de Caracol Radio, el volante antioqueño manifestó que no ve este juego como una revancha y añadió que quieren ser campeones por la hinchada, sus familias y el profesor Alberto Gamero.

Diego Herazo, delantero colombiano que debutó con San Lorenzo de Argentina este martes, habló con El Alargue de Caracol Radio sobre lo que fue su estreno con el equipo de Almagro. Herazo se refirió, entre otras cosas, al apodo que ha recibido de parte de la prensa de ese país, quien lo ha bautizado como el ‘Lukaku colombiano’.

En Caracol Radio estuvo Ana María Vesga, presidenta de Acemi, conversando sobre la situación de Sanitas y la salud del país

Juan Diego Soler, doctor de astrofísica y astronomía, explicó en 6AM la importancia del reciente lanzamiento de Boeing de su primera nave tripulada y qué tan cerca está la humanidad poder disfrutar de viajes al espacio

Get your just desserts at Le Clare's, La Creperie d’Audrey and Sweet NOLA Snoballs.

OMG. I can't believe October is over already. I blame Satisfactory which, okay, I do get it now, and it did destroy my body and mind. I am inches from being done now; I just want to make sure that I finish it with enough force that I do actually put it away, as I could imagine tinkering with my saddest factory forever.

The game isn't without flaw, but I think most of those flaws are not interesting to talk about. I do have one petty but important criticism, which is mildly spoilerful and anyway will only be interesting if you played the game. There is an object called the Somersloop ("cool S") which allows you to double the output of a machine. Canonically this item is some kind of "loop" and the flavor text talks about how it is able to create more energy than you put into it. So when I'm out hunting for Korok seeds I have this thought that maybe I could create a loop of factories whereby it would create infinite resources by repeatedly doubling. And I'm thinking about it but the crafting tree doesn't have any notable loops in it, but I remember the "packager" which allows you to put a fluid in a container or the converse, and I'm like: Yes, that's great! So I get back to base and I am doing this, just for fun to create an infinite fuel factory or whatever, and I realize that the packager just doesn't have a slot for a Somersloop. They must just hate fun, elegant twists. It would not break the game to allow this (you can always get infinite resources lots of other ways) or cause any other problem I can think of. Hmph!

The thing about constructing a factory and watching it churn is that it's basically the same thing as a programming project that you invented for yourself, and it's probably better to do the programming project. Here's progress on my mysterious rectangle:

I've been gradually adding new and older BookADay posts to my new Bookstagram. One of the most recent:

SOUP DAY by Melissa Iwai (Henry Holt): Celebrates the importance of making a nutritious meal and sharing in the process as a famly. Also be sure to check out Melissa's newest book, DUMPLINGS FOR LILI (Norton Young Readers).

α1-antitrypsin (AAT) regulates the activity of multiple proteases in the lungs and liver. A mutant of AAT (E342K) called ATZ forms polymers that are present at only low levels in the serum and induce intracellular protein inclusions, causing lung emphysema and liver cirrhosis. An understanding of factors that can reduce the intracellular accumulation of ATZ is of great interest. We now show that calreticulin (CRT), an endoplasmic reticulum (ER) glycoprotein chaperone, promotes the secretory trafficking of ATZ, enhancing the media:cell ratio. This effect is more pronounced for ATZ than with AAT and is only partially dependent on the glycan-binding site of CRT, which is generally relevant to substrate recruitment and folding by CRT. The CRT-related chaperone calnexin does not enhance ATZ secretory trafficking, despite the higher cellular abundance of calnexin-ATZ complexes. CRT deficiency alters the distributions of ATZ-ER chaperone complexes, increasing ATZ-BiP binding and inclusion body formation and reducing ATZ interactions with components required for ER-Golgi trafficking, coincident with reduced levels of the protein transport protein Sec31A in CRT-deficient cells. These findings indicate a novel role for CRT in promoting the secretory trafficking of a protein that forms polymers and large intracellular inclusions. Inefficient secretory trafficking of ATZ in the absence of CRT is coincident with enhanced accumulation of ER-derived ATZ inclusion bodies. Further understanding of the factors that control the secretory trafficking of ATZ and their regulation by CRT could lead to new therapies for lung and liver diseases linked to AAT deficiency.

General Manager Matt Klentak discussed the Phillies' offseason in a press conference on Thursday in Clearwater, Fla. The Phillies remain in contact with the agents for Bryce Harper and Manny Machado. The belief is that the front office still prefers Machado over Harper because of Machado's combination of offense and defense.

OM worker discovers unlikely friendships among a group of 'misfit toys' in North Africa.

The Government Employees' Pension Fund delivered a return of 4.9% on investments for its members in the year to end-March.

अर्धसैनिक बलों में महिलाओं की भागीदारी और बढ़ने जा रही है. गृह मंत्रालय ने अपने ऐतिहासिक  फैसले में केंद्रीय औद्योगिक सुरक्षा बल (सीआईएसएफ) की पहली महिला बटालियन के गठन को मंजूरी मिल गई है. राष्ट्रीय सुरक्षा में महिलाओं की भूमिका बढ़ाने के लिए यह निर्णय काफी अहम है. फिलहाल  सीआईएसएफ में महिलाओं की भागीदारी 7 फीसदी से अधिक है. 

International Symposium on Forecasting (virtual, June 27 - July 2) The 41st International Symposium on Forecasting will be virtual again this year, and begins Sunday June 27. SAS will have a huge presence -- as event sponsor, sponsor of the IIF/SAS Research Grants, and with 19 individual presentations. ISF registration [...]

The post 19 reasons to attend ISF 2021 (virtual - starting June 27) appeared first on The Business Forecasting Deal.

Could potassium fortification be the answer we're looking for when it comes to battling our unhealthy addiction to salt?

Two decades into the era of Electronic Health Records (EHRs), the promise of streamlining clinical care, reducing burden, and improving patient outcomes has yet to be realized. A cross-sectional family physician census conducted by the American Board of Family Medicine in 2022 and 2023 included self-reported physician EHR satisfaction. Of the nearly 10,000 responding family physicians, only one-in-four (26.2%) report being very satisfied and one-in-three (33.8%) were not satisfied. These low levels of satisfaction point to the need for greater transparency in the marketplace and pressure to increase user-centric EHR design.

People report greater life satisfaction six months after starting Parkrun events, which could partly be due to the supportive environment

À l’exception notable des électeurs conservateurs.

A few dozen ChatGPT queries cost a bottle’s worth of water. Tech firms should consider simpler solutions, such as harvesting rainwater, to meet AI’s needs

Apart from the lead pair, Ram Charan and Kiara Advani, the film features SJ Suryah, Anjali, Jayaram, Naveen Chandra, Sunil, Srikanth, Samuthirakani and Nassar. While it was initially set for a Christmas 2024 release, the film was pushed to January 10, 2025.

Alec Baldwin discharged a prop gun on the set of the Western film “Rust” on Thursday, killing a crew member and wounding the movie director, according to the Santa Fe County Sheriff’s office. Baldwin said Friday that he is fully cooperating with the police investigation. Photo: Jim Weber/Associated Press