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[Capital FM] Nairobi -- Kenya's Sheila Chepkirui held off a stiff challenge from fellow countrywoman, Hellen Obiri, to win the New York Marathon on Sunday -- her first-ever World Marathon Majors triumph.

Odido lanceert Klik&Klaar Internet landelijk en tegen een concurrerend tarief. Het maakt van 5G een serieuze concurrent op de internetmarkt. De risico's zijn kannibalisatie en technologie - kan het netwerk het aan? Dat zal de consument zich ook afvragen. Daardoor is de kwaliteitsperceptie een cruciale succesfactor...

The Conference "Adapting to Global Change in the Mediterranean hotspot - AGCM" will be held in Seville, Spain on 18-20 September 2013. The conference is organised by Donana Biological Station (EBD-CSIC) within the FP7 funded  EcoGenes project.  Its main purpose is to explore and gather a variety of  independent research threads to reveal overall patterns on how the world around us is changing and the many ways different organisms respond to that change.

By bringing together researchers who investigate various aspects of this global change and the way individuals, populations and communities respond to it, and who employ a wide variety of experimental and theoretical tools, the conference aims at hope to make intellectual progress on particular issues and move research in the area forward.

The specific themes that will be addressed are:

• Phenotypic responses to global change
• Breakdown of species boundaries
• Emergent diseases in changing environments
• Responses to past global change
• Adaptation and speciation in response to changing environments
• Biological invasions: from species adaptation to ecosystem responses
• Monitoring ecosystems responses
• Consequences of global change in biotic interactions
• Population responses to global change

AGCM is by invitation only regarding speakers; however participants are invited to submit a proposal for posters.

Poster submission deadline: 17 July 2013
Registration Deadline: 6 September 2013

For more information visit the AGCM website: http://ebdecogenes.ebd.csic.es

This year’s awards, announced at the Total Solutions Plus conference in Boston, celebrate Juan “Junior” Mercado from Christian Brothers Flooring & Interiors as the Commercial Tile Setter Craftsperson of the Year and Jeff Occhipinti from Columbia River Tile & Stone as the Residential Tile Setter Craftsperson of the Year.

It has recently emerged that consumer habits amongst Gen Z are changing, with many now turning to social media for retail therapy. Weighing in on this growing phenomenon of social media shopping, Nick Drewe, founder of the online discount platform Wethrift, offers his insights:

Celebratory Reception and Talk to be Held at El Barrio Artspace PS109 on September 20

Lightspeed Restoration announces that its industry-leading training facility has been officially approved by the Institute of Inspection Cleaning and Restoration Certification (IICRC).

Orlando Fringe has ended its deal with the city and will leave the Church Street ArtSpace by February, leaders say. Finances are to blame.

Host Bob Leins, CPA® welcomes John Jilek, CFP®.

The post Roth vs. Traditional IRA and Roth TSP vs. Pre-tax TSP and a Perspective on RMDs first appeared on Federal News Network.

The TSP board and its contractor have fixed the bulk of the problems. A few remain. Auditors find the big issue was the board's inexperience in acquisition.

The post Two-plus years in, TSP website is almost there first appeared on Federal News Network.

It has recently emerged that consumer habits amongst Gen Z are changing, with many now turning to social media for retail therapy. Weighing in on this growing phenomenon of social media shopping, Nick Drewe, founder of the online discount platform Wethrift, offers his insights:

The L 2070 fund made its debut in late July, adding to the string of positive returns with 2.39% in August.

The post TSP returns for August mostly down, but still positive first appeared on Federal News Network.

A new survey found that TSP participant satisfaction is at 84%, a 2% increase over last year’s results from the Federal Retirement Thrift Investment Board.

The post TSP participant satisfaction rebounds slightly in 2024 survey first appeared on Federal News Network.

Among the core TSP funds, the C Fund showcased the most movement with a 2.13% return in September, bringing its YTD performance to just over 22%.

The post TSP funds posted continued modest gains in September first appeared on Federal News Network.

The Federal Retirement Thrift Investment Board has been trying to reach out directly to TSP participants at risk of missing the full 5% government match.

The post TSP participants contributing too much, too soon could miss out on benefits first appeared on Federal News Network.

How can you maximize every bit of your Thrift Savings Plan?

The post How to maximize your TSP first appeared on Federal News Network.

The Common Stock Index C fund, which dropped -0.91% in October, still is providing the highest year-to-date return among all investment funds.

The post Most TSP funds fall in October, but year-to-date still looks good first appeared on Federal News Network.

It's easy to talk about long-haul, no-panic investing during good times, like we’ve just experienced for an unnaturally long time. But when the going gets tough and markets decline, it is harder to stay the course and sleep at night.

The post The TSP in troubled times: Go long! first appeared on Federal News Network.

On this week's Your Turn, financial advisor Arthur Stein will talk about the future course of your TSP account, and FNN reporter Drew Friedman will talk about the very latest on the federal pay raise. Then we’ll get into the prospects for a large retiree COLA and the issues TSP investors are having with the new system.

The post Pay Raise, COLA, TSP troubles and the G-fund first appeared on Federal News Network.

For many investors, the Thrift Savings Plan will provide anywhere from one-third to half their income in retirement. Assuming, of course, there is income!

The post TSP returns: Who hit the down button? first appeared on Federal News Network.

If you choose the invest-for-the-long haul course you may, as 112,000 rank-and-file federal and postal workers have done, become a TSP millionaire. But the keys are long-term investing and doing what the proven winners have already done.

The post Wanna be a TSP trillionaire? Ask one! first appeared on Federal News Network.

Many investors know the conventional thing to do, when times are good. But when things go south, which they do regularly, the fight-or-flight instinct kicks in. Times like now.

The post TSP tactics: Are you managing the market? Or is it playing you? first appeared on Federal News Network.

For some, TSP (with its generous government match) will provide one-third to as much half the money they have to spend in retirement. Regardless of the percentage, it’s a lot. So how do you become a TSP millionaire?

The post Wanna be a TSP millionaire: Have you got the right stuff? first appeared on Federal News Network.

The new funding will support Wheelocity’s plans to expand operations across 20,000 towns and villages in southern India over the next year, aiming to reach a user base of 10 million.

Artspeak Radio, Wednesday, November 6, 2024, 9am -10am CST, 90.1fm KKFI Kansas City Community Radio, streaming live audio www.kkfi.org Producer/host Maria Vasquez Boyd talks with David Tomas Martinez, Poppy Di […]

The post Artspeak Radio with David Tomas Martinez, Poppy Di Candelo, and Michael Baxley appeared first on KKFI.

Artspeak Radio, Wednesday, November 13, 2024, 9am -10am CST, 90.1fm KKFI Kansas City Community Radio, streaming live audio www.kkfi.org Producer/host Maria Vasquez Boyd talks with Robb Gann, Stacey Busch, Edwing […]

The post Artspeak Radio November Edition appeared first on KKFI.

[Updated with video] Scientists from Nekton undertaking the XL Catlin Deep Ocean Survey, have discovered a new “biological hotspot” on Argus Seamount, some 30 miles south west of Bermuda. Diving in cutting-edge manned submersibles adapted with the latest scientific and filming equipment, the scientists are the first to biologically document and sample the previously unexplored seamount. […]

Heterotrimeric G-proteins are signaling switches broadly divided into four families based on the sequence and functional similarity of their Gα subunits: Gs, Gi/o, Gq/11, and G12/13. Artificial mutations that activate Gα subunits of each of these families have long been known to induce oncogenic transformation in experimental systems. With the advent of next-generation sequencing, activating hotspot mutations in Gs, Gi/o, or Gq/11 proteins have also been identified in patient tumor samples. In contrast, patient tumor-associated G12/13 mutations characterized to date lead to inactivation rather than activation. By using bioinformatic pathway analysis and signaling assays, here we identified cancer-associated hotspot mutations in Arg-200 of Gα13 (encoded by GNA13) as potent activators of oncogenic signaling. First, we found that components of a G12/13-dependent signaling cascade that culminates in activation of the Hippo pathway effectors YAP and TAZ is frequently altered in bladder cancer. Up-regulation of this signaling cascade correlates with increased YAP/TAZ activation transcriptional signatures in this cancer type. Among the G12/13 pathway alterations were mutations in Arg-200 of Gα13, which we validated to promote YAP/TAZ-dependent (TEAD) and MRTF-A/B-dependent (SRE.L) transcriptional activity. We further showed that this mechanism relies on the same RhoGEF-RhoGTPase cascade components that are up-regulated in bladder cancers. Moreover, Gα13 Arg-200 mutants induced oncogenic transformation in vitro as determined by focus formation assays. In summary, our findings on Gα13 mutants establish that naturally occurring hotspot mutations in Gα subunits of any of the four families of heterotrimeric G-proteins are putative cancer drivers.

Dougherty County, a largely black school district in an region heavily affected by coronavirus, is no longer subject to desegregation orders first imposed in 1963.

Read the in depth Review of Logitech G435 LIGHTSPEED Wireless Gaming Headset Gaming. Know detailed info about Logitech G435 LIGHTSPEED Wireless Gaming Headset configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.

Tencent Games subsidiary LightSpeed Studios has announced Hideaki Itsuno, who recently left Capcom after 30 years working for the company, will be leading a new video game studio called LightSpeed Japan Studio.

LightSpeed Japan Studio will have two locations in Tokyo and Osaka and is focused on developing original AAA games.

"Joining LightSpeed Studios is an exciting new chapter for me," said Hideaki Itsuno. "With LightSpeed’s strong development capability and global network, I look forward to creating original AAA action game titles together with the amazing team and building aesthetic and innovative experiences for the global player community. We welcome all talented and passionate game creators from the world over to join our vision."

LightSpeed Studios president Jerry Chen added, "It is our great honor to have Hideaki Itsuno join LightSpeed Studios. The establishment of LightSpeed Japan Studio is a significant step in LightSpeed Studios’ expansion and demonstrates our commitment to bringing the best possible games to our players."

Itsuno directed entries in the Rival Schools, Power Stone, Capcom VS. SNK, Devil May Cry, and Dragon’s Dogma franchises.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/463041/hideaki-itsuno-to-lead-new-aaa-developer-lightspeed-japan-studio/

More than 500 fires have burned across Colombia, including in its delicate and unique highland wetlands, one of the fastest evolving ecosystems on Earth

Studio based in Osaka, Tokyo to focus on AAA action games

Highlights: Adenovirus, typically seen in winter, has affected young swimmers this summer, suggesting pools as

Australian organisations are experiencing a significantly higher rate of economic crime than the rest of the globe according to a PwC survey released today which finds 52 percent experienced economic crime in the last 24 months compared to the global average of 36 percent.

Skyrocketing land prices in adjoining neighbourhoods has given Guindy a new lease of life as a residential market.

In conversation with Niranjan Hiranandani, CMD, Hiranandani Communities, on his plans for Chennai

IEEE / Institute of Electrical and Electronics Engineers Incorporated

Crafts Council of Telangana’s Sanmaan 2023 awardees bat for time-tested techniques and slow fashion

The company claims its technology will allow it to access previously undruggable targets