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Govt announces guidelines for funding testing facilities under National Green Hydrogen Mission

With a budget of ₹200 crore till FY26, the scheme aims to support the development of standards and regulatory frameworks in the Green Hydrogen sector.




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Govt issues operational guidelines for under PM-Surya Ghar: Muft Bijli Yojana

A total financial outlay of ₹800 crore has been allocated for this component, providing ₹1 crore per selected model solar village, the Ministry said




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Govt supports e-commerce but demands fair play and honesty, says Piyush Goyal

Goyal highlighted the benefits of e-commerce while expressing concerns about predatory pricing practices and the need to protect small retailers




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Defence Ministry cautions firms using Chinese parts for drones

Ministry dashes off a letter to industry bodies asking them to sensitise manufacturers against using Chinese parts for drones




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QR code diktat to be widened for more medicines, says DCGI Raghuvanshi 

already Top 300 drug brands are already under mandatory QR code net 




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Ceiling prices of 8 common drugs raised by 50%, these medicines treat asthma, tuberculosis, others...

The National Pharmaceutical Pricing Authority (NPPA) has sanctioned the ceiling price hike for 11 formulations by 50 per cent in response to representations from drug makers.




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Panel to inventory jewellery, precious stones in the Ratna Bhandar of the Shree Jagannath Temple in Puri

Arijit Pasayat, former Supreme Court judge, will head the 12-member committee 




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Bagnaia wins Indonesia Grand Prix sprint to close on Martin

The Italian Ducati rider's sprint victory in sweltering conditions at the Mandalika International Street Circuit moved him up to 329 points, 12 behind Martin




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Weight management is athlete’s responsibility, says Mary Kom on Vinesh Phogat’s Olympic disqualification

Vinesh Phogat, who was being seen as gold medal contender in Paris Olympics, was disqualified from competing in the final of the 50kg weight class for being 100 grams over the permissible limit




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Bagnaia wins Japanese Grand Prix sprint after leader Acosta crashes

Rookie Acosta, who took pole earlier in the day, had overtaken Bagnaia on the third lap to take the lead, but lost control near turn seven, losing the opportunity to win his first MotoGP sprint




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Under-23 World Wrestling Championships: Chirag Chikkara clinches gold as India shines with nine medals

Chirag Chikkara becomes the second Indian man, after Paris Olympics bronze medallist Aman Sehrawat, to win the gold at the U23 Championships.




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Taiwan closes exploding pagers case, says not made by Taiwanese firms

Taiwan closes probe into pagers exploding in Lebanon, absolving citizens and companies of involvement in Hezbollah incident




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China to unveil stealth fighter jet and attack drones at Zhuhai airshow

The country's close ties with Moscow will also be on display at Airshow China, which showcases Beijing's civil and military aerospace sector every two years in the southern city of Zhuhai




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Tirupati witnesses brisk sale of white pumpkins during Deepavali season

Not just pumpkins, but flowers such as marigold and chrysanthemum also saw a roaring business this season, to be adorned to the shopping outlets and vehicles




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Drones to be deployed to check sand smuggling

The unmanned aerial vehicles will be used to check illegal sand mining, smuggling, stock-keeping, and selling sand on the black market, says Police Commissioner




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An electrochemiluminescence microsensor based on DNA-silver nanoclusters amplification for detecting cellular adenosine triphosphate

Anal. Methods, 2024, 16,2019-2024
DOI: 10.1039/D4AY00212A, Paper
GuanQi Wu, Jian Chen, JinXin Dou, XiangWei He, Hai-Fang Li, Jin-Ming Lin
An ECL microsensor integrating RCA magnification and in situ DNA-templated AgNC generation for sensitive detection of cellular ATP.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Luminescent and time-resolved determination of gemifloxacin mesylate in pharmaceutical formulations and spiked blood plasma samples using a lanthanide complex as a probe

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00236A, Paper
Gasser M. Khairy, Rania M. Goda, Zeinab M. Anwar, Mohamed M. Aboelnga, Axel Duerkop
A new luminescent europium probe for the determination of the antibiotic gemifloxacin is presented. Time-resolved luminescence enables its quantitation in pharmaceutical formulations and blood samples.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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The selective extraction of dietary polyamines from chicken breast using the application of a lab-on-a-chip electromembrane and dispersive liquid–liquid microextraction followed by gas chromatography-mass spectrometry

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02172F, Paper
Fatemeh Barzegar, Samaneh Nabizadeh, Marzieh Kamankesh, Jahan B. Ghasemi, Abdorreza Mohammadi
Excessive dietary polyamines (PAs), including putrescine (PUT), spermine (SPM), and spermidine (SPD), have become a worldwide concern due to their carcinogenicity and reduced shelf life.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Dual-signal detection of tannin acid in red wines based on peroxidase activity carbon dots

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00526K, Paper
Bin Liu, Yu Yin, qianwen Li, wanwan Li, Fubing Xiao, Jinquan Liu, Yan Tan, Shengyuan Yang
Herein, a novel sort of phosphorus and iron-doped carbon dots (P,Fe-CDs) with outstanding peroxidase activity and excellent fluorescence performance was hydrothermally synthesized to colorimetrically and fluorimetrically detect tannic acid (TA)....
The content of this RSS Feed (c) The Royal Society of Chemistry




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Fe3+-induced luminescence quenching in carbon dots – mechanism unveiled

Anal. Methods, 2024, 16,2349-2358
DOI: 10.1039/D3AY02202A, Paper
Varsha Raveendran P.T., Anjali C., Renuka Neeroli Kizhakayil
Luminescence quenching in carbon dots with an increase in Fe3+ concentration and the quantitative variation in luminescence intensity with added ferric ions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A chemiluminescence immunoassay for type IV collagen as a promising marker for liver fibrosis and cirrhosis

Anal. Methods, 2024, 16,2248-2255
DOI: 10.1039/D3AY02240D, Paper
Xiaoling Fu, Fan Zhang, Fangda Zhen, Lian Duan, Jian Zhou, Jianguo Ma
Herein, a magnetic bead-based chemiluminescence assay is reported to detect type IV collagen (col-IV) in serum samples.
The content of this RSS Feed (c) The Royal Society of Chemistry




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 Milestones and U-turns: On the government in its third term

The optics of the 100-day mark cannot conceal changed dynamics for the BJP




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​Tough task: On the battle lines in the Jharkhand Assembly election

Coalitional incoherence could stymie the INDIA bloc’s effort to retain power in Jharkhand




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Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00660G, Review Article
Shutang Li, Jinfei Yang
As research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery and optimisation of pyrazolo[1,5-a]pyrimidines as aryl hydrocarbon receptor antagonists

RSC Med. Chem., 2024, 15,3477-3484
DOI: 10.1039/D4MD00266K, Research Article
Raitis Bobrovs, Svetlana Terentjeva, Ninni Elise Olafsen, Zilvinas Dambrauskas, Antanas Gulbinas, Toivo Maimets, Indrek Teino, Aigars Jirgensons, Jason Matthews, Kristaps Jaudzems
The aryl hydrocarbon receptor (AHR) is a versatile ligand-dependent transcription factor involved in diverse biological processes, from metabolic adaptations to immune system regulation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Inhibition of monoamine oxidases by heterocyclic derived conjugated dienones: synthesis and in vitro and in silico investigations

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00608A, Research Article
Sunil Kumar, Bishnu Prasad Pandey, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Rania B. Bakr, Hoon Kim, Bijo Mathew
A total of 18 heterocyclic derived conjugated dienones (CD1–CD18) were evaluated for their potential monoamine oxidase (MAO)-A/-B inhibitory activity.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis and evaluation of tetrahydropyrrolo[1,2-a]quinolin-1(2H)-ones as new tubulin polymerization inhibitors

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00541D, Research Article
Mikhail N. Anisimov, Maksim A. Boichenko, Vitaly V. Shorokhov, Julia N. Borzunova, Marina Janibekova, Vadim V. Mustyatsa, Ilya A. Lifshits, Andrey Yu. Plodukhin, Ivan A. Andreev, Nina K. Ratmanova, Sergey S. Zhokhov, Elena A. Tarasenko, Daria A. Ipatova, Alexander R. Pisarev, Ivan A. Vorobjev, Igor V. Trushkov, Olga A. Ivanova, Nikita B. Gudimchuk
New 1,5-disubstituted pyrrolidin-2-ones 1, 2 and 5-aryl-3,3a,4,5-tetrahydropyrrolo[1,2-a]quinoline-1(2H)-ones 3 were explored as inhibitors of tubulin polymerization.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Novel benzenesulfonamides containing a dual triazole moiety with selective carbonic anhydrase inhibition and anticancer activity

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00617H, Research Article
Aida Buza, Cüneyt Türkeş, Mustafa Arslan, Yeliz Demir, Busra Dincer, Arleta Rifati Nixha, Şükrü Beydemir
In this research, a series of sulfonamides incorporating a 1,2,3-triazolyloxime substituted 1,2,3-triazolyl moiety was conceptualized, synthesized, and investigated as carbonic anhydrase inhibitors.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00511B, Research Article
Open Access
Francesco Melfi, Marialuigia Fantacuzzi, Simone Carradori, Ilaria D'Agostino, Alessandra Ammazzalorso, Noemi Mencarelli, Marialucia Gallorini, Mattia Spano, Paolo Guglielmi, Mariangela Agamennone, Sazan Haji Ali, Ali Al-Samydai, Francesca Sisto
Monoterpene-derived azo benzenes showed selective antibacterial activity against Helicobacter pylori with a safe profile. An in silico investigation highlighted the inosine 5'-monophosphate dehydrogenase enzyme as the putative target.
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Metal-free synthesis of N-fused quinazolino-quinazoline-diones as a MALAT1 RNA triple helix intercalator

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00614C, Research Article
Vijay Babu Pathi, Pranotosh Das, Abhyuday Guin, Manish Debnath, Biswadip Banerji
The development of chemical scaffolds that target highly conserved MALAT1 RNA received attention due to its significance in splicing, nuclear organization, and gene expression in disease progression pathways.
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Generation and capture of naphthoquinonynes: a new frontier in the development of trypanocidal quinones via aryne chemistry

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00558A, Research Article
Laura P. R. Figueroa, Renato L. de Carvalho, Renata G. Almeida, Esther R. S. Paz, Emilay B. T. Diogo, Maria H. Araujo, Warley S. Borges, Victor F. S. Ramos, Rubem F. S. Menna-Barreto, James M. Wood, John F. Bower, Eufrânio N. da Silva Júnior
This article presents A-ring functionalized quinones via a modern and efficient new strategy involving the generation and capture of benzyne quinones and their evaluation against Trypanosoma cruzi.
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Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00553H, Research Article
Stefano Tomassi, Benito Natale, Michele Roggia, Luisa Amato, Caterina De Rosa, Carminia Maria Della Corte, Emma Baglini, Giorgio Amendola, Anna Messere, Salvatore Di Maro, Elisabetta Barresi, Federico Da Settimo, Maria Letizia Trincavelli, Fortunato Ciardiello, Sabrina Taliani, Floriana Morgillo, Sandro Cosconati
Non-small cell lung cancer (NSCLC), the leading cause of cancer-related mortality worldwide, poses a formidable challenge due to its heterogeneity and the emergence of resistance to targeted therapies.
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Guidelines issued for fertilizer distribution in Karaikal for samba, thaladi paddy cultivation




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Tiruchi Corporation office expansion plan witnesses more delay




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576: Blocks, Components, Linting Images, Engines, and “Web Integrity”

We're talking how we stay online - or not - on vacation, is create-guten-block the future for us WP developers? Can we get a state of the web component address from the President of web components? Have we seen the last new browser engine? And deciding whether to add features or remove them from your app.




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589: CSS Functions, Read It Later, Making Money in Business, and More

A quick bit of union news follow up, CSS function round up, Read It Later inside Feedbin, fun uses for a Stream Deck+, how to turn up the money dial in your own business, and having the audacity to call yourself a publisher.




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Guidelines for green urbanisation

The Ministry of Urban Development has proposed environmental guidelines for construction projects in urban areas. Nidhi Adlakha reports




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A premium for cleanliness

If you’re looking at buying a home, take a pick from one of India’s cleanest cities.




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The last thing business founders need is a wasteful public spat

As entrepreneurship explodes in India, we need more iconic founders who not only build sustainable firms but also retain their humility




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Cargo companies upsize for new business

Booming demand for ecommerce delivery spurs freight handlers to open more centres, digitise for efficiency




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Making medicines at the point of patient care

UK readies law allowing preparation of medicines near hospital setting to reach patients safely, quickly




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India's climate policies expected to reduce CO2 emissions by around 4 billion tonnes by 2030: Report

The study by Delhi-based independent think tank Council on Energy, Environment and Water (CEEW) said policies for India's power, residential and transport sectors have already saved 440 million tonnes of carbon dioxide (MtCO2) between 2015 and 2020.




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Values that make a business tick

The authors use their experience to show that business should be about ethics, dharma and more




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Cashing out of a business, smartly

The book draws upon diverse experiences of entrepreneurs to highlight the need for an exit strategy




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Centre to provide 15,000 women self help groups with drones that can be rented out for agricultural purposes

The scheme will help in infusing advanced technology in agriculture for improved efficiency, enhance crop yield and reduced cost of operation for the benefit of farmers




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KAU, Asia’s largest cocoa germplasm repository, ready to release six more clones




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Business confidence dips to 5-month low in May




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Mphasis Q4 net profit declines 13% to Rs. 155 crore




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RBI panel to study FinTech business in India




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Sun Pharma to focus on skincare to boost OTC business