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Elon Musk's Starlink Working on Indian Security Clearance for Satellite Broadband

Starlink has been looking to enter India for years and its plans got a major boost last month when New Delhi said it wouldn't auction spectrum for satellite broadband but rather award it administratively - just as Musk wanted. Rival Indian telecom billionaire Mukesh Ambani had wanted an auction.




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Spotlight on SiriusDecisions: Artificial Intelligence

Kerry Cunningham of SiriusDecisions talks about how AI can power the B2B revenue engine




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State Releases Guidance on Generative Artificial Intelligence in Classrooms

The Delaware Department of Education has developed guidance for districts and charter schools on generative artificial intelligence (AI) in the classroom.




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Storytelling is Key, in Email and Everywhere Else

Insights from Emma and their customers on storytelling across marketing channels, from the Marketing United summit




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SAS Customer Intelligence 360: Introduction to marketing data management

No matter what your brand's level of marketing maturity is, SAS can help you move from data to insight to action with rich functionality for adaptive planning, journey activation and an embedded real-time decision engine – all fueled by powerful analytics and artificial intelligence (AI) capabilities. Let's begin with a [...]

SAS Customer Intelligence 360: Introduction to marketing data management was published on Customer Intelligence Blog.




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SAS Customer Intelligence 360: Identity management, profiling and unified data model for hybrid marketing

Customer data platforms (CDPs), data management platforms (DMPs), people-based marketing, identity graphs, and more overlapping topics represent an important ingredient of any martech brainstorming session in 2020. As your brand spreads out across touchpoints — from web to mobile applications, as well as call centers, email and direct mail — [...]

SAS Customer Intelligence 360: Identity management, profiling and unified data model for hybrid marketing was published on Customer Intelligence Blog.




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SAS Customer Intelligence 360: Behavioral event tracking, targeting & engagement analysis

There's no question that we're all increasingly, and often exclusively, interacting with brands digitally. Consumers are now online through countless mechanisms – from laptops and mobile apps to AI-enabled voice assistants and sensor-based wearables. Engagement is diversifying in fascinating new ways. And when organizations can't see their customers interacting in [...]

SAS Customer Intelligence 360: Behavioral event tracking, targeting & engagement analysis was published on Customer Intelligence Blog.




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SAS Customer Intelligence 360: Enriching analysis with device usage data

Over the last 20+ years, global society has adopted digital devices at scale, and consumer interaction behaviors continually evolve and mature. As analysts, we're uniquely positioned to notice worldwide trends, country-specific nuances and localized market behaviors that can have significant impact on our brand's business goals. This global scope is [...]

SAS Customer Intelligence 360: Enriching analysis with device usage data was published on Customer Intelligence Blog.




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SAS Customer Intelligence 360: Automated explanation and supervised segmentation

One of the wonderful aspects about my client-facing role at SAS is the breadth of audiences that I get to work with. No matter where you fall on this list: Data engineer. Business or marketing analyst. Citizen data scientist. Data scientist. Statistician. Executive. One topic is certain: We all love [...]

SAS Customer Intelligence 360: Automated explanation and supervised segmentation was published on Customer Intelligence Blog.




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SAS Customer Intelligence 360: Make better decisions with analytically driven marketing

According to the SAS Experience 2030 global study, by the year 2030 67% of in-person customer engagements (think sales assistance and information queries) will be completed by smart machines rather than humans. And while it may seem a bit ironic, the most personalized customer experiences could involve no people at [...]

SAS Customer Intelligence 360: Make better decisions with analytically driven marketing was published on Customer Intelligence Blog.




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SAS Customer Intelligence 360: Visual analytics, sankey diagrams and customer journeys

We live in the age of data. From global warming stats to customer behavior patterns, new technologies have made it easier to collect, store, access and analyze information. But our use of these technologies has also eroded our attention spans and fueled post-truth misunderstandings. To combat these trends, the question [...]

SAS Customer Intelligence 360: Visual analytics, sankey diagrams and customer journeys was published on Customer Intelligence Blog.




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SAS Customer Intelligence 360: Data visualization, location analytics and geospatial insights

Everything happens somewhere, and much of our customer data includes location information. Websites include x, y coordinates in semi-structured click streams, and the mobile apps your prospects depend on frequently support device location to provide a personalized, targeted experience. As my SAS peer Robby Powell said: "Human brains are hardwired [...]

SAS Customer Intelligence 360: Data visualization, location analytics and geospatial insights was published on Customer Intelligence Blog.




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UK University Tells Rich Students To Not Be A 'Snob' To Poorer Classmates

A guidance has been issued to the wealthier students with a list of actions they need to follow to create an inclusive environment.




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how to tell conformal to ignore certain combination of input

hi

How can I tell the LEC tool to ignore a combination of Primary input bus in both Golden and revised.

For example in both Golden and revised there is 

input [3:0] data_in

I want LEC not to check the case that data_in[3:0] == 4'b1000




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Moving Beyond EDA: The Intelligent System Design Strategy

The rising customer expectations, intermingling fields and high performance needs can be satisfied with the system based design. An intelligent Systems Design strategy can offer a quicker route to an optimum design and helps to increase designers' productivity and analyzes efficiency by providing the ability to explore the entire design space. Cadence Intelligent System Strategy enables a system design revolution and reduces project schedules with optimized continuous integration.(read more)




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IntelliGen Statistics Metrics Collection Utilility

As noted in white papers, posts on the Team Specman Blog, and the Specman documentation, IntelliGen is a totally new stimulus generator than the original "Pgen" and, as a result, there is some amount of effort needed to migrate an existing verification environment to fully leverage the power of IntelliGen.  One of the main steps in migrating code is running the linters on your code and adressing the issues highlighted. 

Included below is a simple utility you can include in your environment that allows you to collect some valuable statistics about your code base to allow you to better gauge the amount of work that might be required to migrate from Pgen to IntelliGen.  The ICFS statistics reported are of particular benefit as the utility not only identifies the approximate number of ICFSs in the environment, it also breaks the total number down according to generation contexts (structs/units and gen-on-the-fly statements) allowing you to better focus your migration efforts. 

IMPORTANT: Sometimes a given environment can trigger a large number of IntelliGen linting messages right off the bat.  Don't let this freak you out!  This does not mean that migration will be a long effort as quite often some slight changes to an environment remove a large number of identified issues.  I recently encountered a situation where a simple change to three locations in the environment, removed 500+ ICFSs!

The methods included in the utility can be used to report information on the following:
- Number of e modules
- Number of lines in the environment (including blanks and comments)
- Number and type of IntelliGen Guidelines linting messages
- Number of Inconsistently Connected Field Sets (ICFSs)
- Number of ICFS contexts and how many ICFSs per context
- Number of soft..select overlays found in the envioronment
- Number of Laces identified in the environment


To use the code below, simply load it before/after loading e-code and then
you can execute any of the following methods:

- sys.print_file_stats()             : prints # of lines and files
- sys.print_constraint_stats()   : prints # of constraints in the environment
- sys.print_guideline_stats()    : prints # of each type of linting message
- sys.print_icfs_stats()            : prints # of ICFSs, contexts and #ICFS/context
- sys.print_soft_select_stats() : prints # of soft select overlay issues
- sys.print_lace_stats()           : *Only works for SPMNv6.2s4 and later* prints # of laces identified in the environment

Each of the above calls to methods produces it's own log files (stored in the current working directory) containing relevant information for more detailed analysis.
- file_stats_log.elog : Output of "show modules" command
- constraint_log.elog : Output of the "show constraint" command
- guidelines_log.elog : Output of "gen lint -g" (with notification set to MAX_INT in order to get all warnings)
- icfs_log.elog       : Output of "gen lint -i" command
- soft_select_log.elog: Output of the "gen lint -s" command
- lace_log.elog       : Output of the "show lace" command


Happy generating!

Corey Goss




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EVM and constellation of mixer

Hello,

I am trying to design an RF mixer for a TX.
Assume my input IF signal is at 1 GHz, my LO at 2 GHz and I want my RF at 3 GHz, and assume that the mixer fully works after testing it with HB.
How to simply set the envelope analysis to check the EVM ?
I read through the documentation but I couldn't get it (I couldn't fully understand the settings of the source, probe, analysis.)
Which source and probe to use? I want custom modulation with custom bandwidth and center frequency.
Is there some examples for the ENVLP analysis ?

I am using IC23.1 and spectre 20.1.354.




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Artificial Intelligence: Accelerating Knowledge in the Digital Age!

In an era of abundant and constantly evolving information, the challenge is not just accessing knowledge but understanding and applying it effectively. AI is a transformative technology that is reshaping how we learn, work, and grow. In this blog, we’ll explore how AI accelerates our knowledge acquisition and understand how it can relate to the process of learning, which connects with our daily lives.

The role of AI is to accelerate knowledge by personalizing learning experiences, providing instant access to information, and offering data-driven insights. AI empowers us to learn more efficiently and effectively in many ways. I won't go into much detail, as we are already busy searching for the meaning of AI and what it can do; however, I want to share one inspiring fact about AI. It can analyze vast amounts of data in seconds, making sense of complex information and providing instantaneous actionable insights or concise answers. I understand that humans are looking to speed up things, which can help us understand technology better and perform our tasks faster.

The main reason AI is in focus is because of its ability to perform tasks faster than ever. We aim to enhance the performance of all our products, including the everyday household electronic items we use. Similarly, are we striving to accelerate the learning process? I am committed to assisting you, and one such method is concise, short (minute-long) videos.

In today's fast-paced world, where attention spans are shorter than ever, the rise of social media platforms has made it easier for anyone to create and share short videos. This is where minute videos come in. These bite-sized clips offer a quick and engaging way to deliver information to the audience with a significant impact. Understanding the definitions of technical terms in VLSI Design can often be accomplished in just a minute.

Below are the definitions of the essential stages in the RTL2GDSII Flow. For further reference, these definitions are also accessible on YouTube.

What is RTL Coding in VLSI Design?

     

What is Digital Verification?

     

What Is Synthesis in VLSI Design?

     

What Is Logic Equivalence Checking in VLSI Design?

     

What Is DFT in VLSI Design?

     

What is Digital Implementation?

     

What is Power Planning?

     

What are DRC and LVS in Physical Verification?

     

What are On-Chip Variations?  

     

Want to Learn More?

The Cadence RTL-to-GDSII Flow training is available as both "Blended" and "Live" Please reach out to Cadence Training for further information.

And don't forget to obtain your Digital Badge after completing the training!

Related Blogs

Training Insights – Why Is RTL Translated into Gate-Level Netlist?

Did You Miss the RTL-to-GDSII Webinar? No Worries, the Recording Is Available!

It’s the Digital Era; Why Not Showcase Your Brand Through a Digital Badge!

Binge on Chip Design Concepts this Weekend!




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iOS 18.2 beta 3: 4 Apple Intelligence features you can test now

Apple's latest beta for iOS 18.2 features some important AI features you can test out now.




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Apple Intelligence on Mac: 5 AI-powered features you can test right now

With the recent macOS Sequoia launch, Apple released some Apple Intelligence features. Here's what you can try out now.




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China’s Push Into Artificial Intelligence―How Should the United States Respond?

China’s Push Into Artificial Intelligence―How Should the United States Respond? China’s Push Into Artificial Intelligence―How Should the United States Respond?
ferrard Thu, 05/03/2018 - 16:49

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore




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Catching Up in a Technology War—China's Challenge in Artificial Intelligence

Catching Up in a Technology War—China's Challenge in Artificial Intelligence Catching Up in a Technology War—China's Challenge in Artificial Intelligence
Anonymous (not verified) Tue, 06/16/2020 - 11:20

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore




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Forging a New Ethical Relationship with Artificial Intelligence

Forging a New Ethical Relationship with Artificial Intelligence Forging a New Ethical Relationship with Artificial Intelligence
venkatp Wed, 06/30/2021 - 15:28

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore




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Soweto Fashion Week Showcased Global Talent with Stellar Line-Up of International and Local Designers




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'History is back, and the old normal isn’t returning' Bari Weiss tells young Jewish leaders


The Free Press founder urges Jewish leaders to confront rising antisemitism and embrace resilience in her powerful DC speech.




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Somalia's Intelligence Agency Arrests Two Al-Shabaab Affiliates in Mogadishu

[Shabelle] Mogadishu, Somalia -- The National Intelligence and Security Agency (NISA) of Somalia announced on Thursday the arrest of two men with ties to the militant group Al-Shabaab in the capital city of Mogadishu.




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Somali Intelligence Agency Nisa Reports Killing 23 Al-Shabaab Militants in Operation

[Shabelle] Mogadishu -- Somalia's National Intelligence and Security Agency (NISA) conducted a targeted operation in the Dharaarweyn area near Galcad city, within the Galgaduud region.




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Satellite images show China working on nuclear reactor for new warship

Satellite images show China working on nuclear reactor for new warship




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Jennifer Aniston recalls one producer telling her 'Friends' won't make her popular

Jennifer Aniston is one of the highest paid actresses of HollywoodAmerican actress, Jennifer Aniston revealed that she was once told by one of her show’s producers that popular sitcom Friends will not 'make her a star'. Globally acclaimed NBC show aired on TV in 1994. At the same time,...




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How big is the universe? The shape of space-time could tell us

We may never know what lies beyond the boundaries of the observable universe, but the fabric of the cosmos can tell us whether the universe is infinite or not




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How to tell if your immune system is weak or strong

New blood tests can reveal whether your immune system is fighting fit by looking at the balance of different immune cells, but there may be a simpler way of gauging your immune health




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The AI expert who says artificial general intelligence is nonsense

Artificial intelligence has more in common with ants than humans, says Neil Lawrence. Only by taking a more nuanced view of intelligence can we see how machines will truly transform society




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Tonga volcano eruption disrupted satellites halfway around the world

A link between volcanic activity and rising bubbles of low pressure in the ionosphere has now been proven, which may be why the colossal Tonga volcano eruption in 2022 disrupted satellite communications




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Ancient DNA tells story of toddler who lived in Italy 17,000 years ago

A young boy who lived towards the end of the last glacial period had dark skin, blue eyes and a congenital heart condition, a study of his genome reveals




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Main Dishes May Fall Flat After Stellar Appetizers

Title: Main Dishes May Fall Flat After Stellar Appetizers
Category: Health News
Created: 8/21/2015 12:00:00 AM
Last Editorial Review: 8/24/2015 12:00:00 AM




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Many Parents Don't Tell Doctor About 'Complementary' Therapy Use in Kids

Title: Many Parents Don't Tell Doctor About 'Complementary' Therapy Use in Kids
Category: Health News
Created: 8/29/2017 12:00:00 AM
Last Editorial Review: 8/30/2017 12:00:00 AM




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Fratelli Beretta Antipasto Trays Are the Source of Salmonella Outbreak: CDC

Title: Fratelli Beretta Antipasto Trays Are the Source of Salmonella Outbreak: CDC
Category: Health News
Created: 8/27/2021 12:00:00 AM
Last Editorial Review: 8/27/2021 12:00:00 AM




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Alternative Medicine Popular Among Seniors, But Most Don't Tell Their Doctors About It

Title: Alternative Medicine Popular Among Seniors, But Most Don't Tell Their Doctors About It
Category: Health News
Created: 7/27/2022 12:00:00 AM
Last Editorial Review: 7/27/2022 12:00:00 AM




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How Can You Tell if Your Baby Has an Earache?

Title: How Can You Tell if Your Baby Has an Earache?
Category: Diseases and Conditions
Created: 6/16/2021 12:00:00 AM
Last Editorial Review: 8/23/2022 12:00:00 AM




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Is It Parkinson's? These 10 Signs Could Tell

Title: Is It Parkinson's? These 10 Signs Could Tell
Category: Health News
Created: 8/19/2022 12:00:00 AM
Last Editorial Review: 8/19/2022 12:00:00 AM




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Family Medicine Must Prepare for Artificial Intelligence

Artificial Intelligence (AI) is poised to revolutionize family medicine, offering a transformative approach to achieving the Quintuple Aim. This article examines the imperative for family medicine to adapt to the rapidly evolving field of AI, with an emphasis on its integration in clinical practice. AI's recent advancements have the potential to significantly transform health care. We argue for the proactive engagement of family medicine in directing AI technologies toward enhancing the "Quintuple Aim."

The article highlights potential benefits of AI, such as improved patient outcomes through enhanced diagnostic tools, clinician well-being through reduced administrative burdens, and the promotion of health equity by analyzing diverse data sets. However, we also acknowledge the risks associated with AI, including the potential for automation to diverge from patient-centered care and exacerbate health care disparities. Our recommendations stress the need for family medicine education to incorporate AI literacy, the development of a collaborative for AI integration, and the establishment of guidelines and standards through interdisciplinary cooperation. We conclude that although AI poses challenges, its responsible and ethical implementation can revolutionize family medicine, optimizing patient care and enhancing the role of clinicians in a technology-driven future.




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Artificial Intelligence and Family Medicine

Artificial intelligence (AI) is certainly going to have a large, potentially huge, impact on the practice of family medicine. The specialty is fortunate to have leading experts in the field to guide us along the way. One such team of forward thinkers provides insights into where AI can take the specialty. Another article reports on how well AI performed on the American Board of Family Medicine In-Training Examination. In addition to AI, we have 3 articles that investigate the intersection of social needs and the practice of medicine. Four clinical review articles cover nonalcoholic fatty liver disease, headache treatments, single maintenance and reliever therapy for asthma, and the use of cannabis in the setting of chronic pain. The clinical research articles cover point-of-care hemoglobin A1c testing, continuous glucose monitoring, and screening for HIV. Another group of articles examines the profession of family medicine, covering topics ranging from how women family physicians negotiate their first jobs to the words we use to define primary care.




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A Review of Artificial Intelligence and Machine Learning in Product Life Cycle Management

The pursuit of harnessing data for knowledge creation has been an enduring quest, with the advent of machine learning (ML) and artificial intelligence (AI) marking significant milestones in this journey. ML, a subset of AI, emerged as the practice of employing mathematical models to enable computers to learn and improve autonomously based on their experiences. In the pharmaceutical and biopharmaceutical sectors, a significant portion of manufacturing data remains untapped or insufficient for practical use. Recognizing the potential advantages of leveraging the available data for process design and optimization, manufacturers face the daunting challenge of data utilization. Diverse proprietary data formats and parallel data generation systems compound the complexity. The transition to Pharma 4.0 necessitates a paradigm shift in data capture, storage, and accessibility for manufacturing and process operations. This paper highlights the pivotal role of AI in converting process data into actionable knowledge to support critical functions throughout the whole product life cycle. Furthermore, it underscores the importance of maintaining compliance with data integrity guidelines, as mandated by regulatory bodies globally. Embracing AI-driven transformations is a crucial step toward shaping the future of the pharmaceutical industry, ensuring its competitiveness and resilience in an evolving landscape.




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Validation of an Artificial Intelligence-Based Prediction Model Using 5 External PET/CT Datasets of Diffuse Large B-Cell Lymphoma

The aim of this study was to validate a previously developed deep learning model in 5 independent clinical trials. The predictive performance of this model was compared with the international prognostic index (IPI) and 2 models incorporating radiomic PET/CT features (clinical PET and PET models). Methods: In total, 1,132 diffuse large B-cell lymphoma patients were included: 296 for training and 836 for external validation. The primary outcome was 2-y time to progression. The deep learning model was trained on maximum-intensity projections from PET/CT scans. The clinical PET model included metabolic tumor volume, maximum distance from the bulkiest lesion to another lesion, SUVpeak, age, and performance status. The PET model included metabolic tumor volume, maximum distance from the bulkiest lesion to another lesion, and SUVpeak. Model performance was assessed using the area under the curve (AUC) and Kaplan–Meier curves. Results: The IPI yielded an AUC of 0.60 on all external data. The deep learning model yielded a significantly higher AUC of 0.66 (P < 0.01). For each individual clinical trial, the model was consistently better than IPI. Radiomic model AUCs remained higher for all clinical trials. The deep learning and clinical PET models showed equivalent performance (AUC, 0.69; P > 0.05). The PET model yielded the highest AUC of all models (AUC, 0.71; P < 0.05). Conclusion: The deep learning model predicted outcome in all trials with a higher performance than IPI and better survival curve separation. This model can predict treatment outcome in diffuse large B-cell lymphoma without tumor delineation but at the cost of a lower prognostic performance than with radiomics.




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Deep Learning-Based Reconstruction of 3D T1 SPACE Vessel Wall Imaging Provides Improved Image Quality with Reduced Scan Times: A Preliminary Study [ARTIFICIAL INTELLIGENCE]

BACKGROUND AND PURPOSE:

Intracranial vessel wall imaging is technically challenging to implement, given the simultaneous requirements of high spatial resolution, excellent blood and CSF signal suppression, and clinically acceptable gradient times. Herein, we present our preliminary findings on the evaluation of a deep learning–optimized sequence using T1-weighted imaging.

MATERIALS AND METHODS:

Clinical and optimized deep learning–based image reconstruction T1 3D Sampling Perfection with Application optimized Contrast using different flip angle Evolution (SPACE) were evaluated, comparing noncontrast sequences in 10 healthy controls and postcontrast sequences in 5 consecutive patients. Images were reviewed on a Likert-like scale by 4 fellowship-trained neuroradiologists. Scores (range, 1–4) were separately assigned for 11 vessel segments in terms of vessel wall and lumen delineation. Additionally, images were evaluated in terms of overall background noise, image sharpness, and homogeneous CSF signal. Segment-wise scores were compared using paired samples t tests.

RESULTS:

The scan time for the clinical and deep learning–based image reconstruction sequences were 7:26 minutes and 5:23 minutes respectively. Deep learning–based image reconstruction images showed consistently higher wall signal and lumen visualization scores, with the differences being statistically significant in most vessel segments on both pre- and postcontrast images. Deep learning–based image reconstruction had lower background noise, higher image sharpness, and uniform CSF signal. Depiction of intracranial pathologies was better or similar on the deep learning–based image reconstruction.

CONCLUSIONS:

Our preliminary findings suggest that deep learning–based image reconstruction–optimized intracranial vessel wall imaging sequences may be helpful in achieving shorter gradient times with improved vessel wall visualization and overall image quality. These improvements may help with wider adoption of intracranial vessel wall imaging in clinical practice and should be further validated on a larger cohort.




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Artificial Intelligence Efficacy as a Function of Trainee Interpreter Proficiency: Lessons from a Randomized Controlled Trial [RESEARCH]

BACKGROUND AND PURPOSE:

Recently, artificial intelligence tools have been deployed with increasing speed in educational and clinical settings. However, the use of artificial intelligence by trainees across different levels of experience has not been well-studied. This study investigates the impact of artificial intelligence assistance on the diagnostic accuracy for intracranial hemorrhage and large-vessel occlusion by medical students and resident trainees.

MATERIALS AND METHODS:

This prospective study was conducted between March 2023 and October 2023. Medical students and resident trainees were asked to identify intracranial hemorrhage and large-vessel occlusion in 100 noncontrast head CTs and 100 head CTAs, respectively. One group received diagnostic aid simulating artificial intelligence for intracranial hemorrhage only (n = 26); the other, for large-vessel occlusion only (n = 28). Primary outcomes included accuracy, sensitivity, and specificity for intracranial hemorrhage/large-vessel occlusion detection without and with aid. Study interpretation time was a secondary outcome. Individual responses were pooled and analyzed with the t test; differences in continuous variables were assessed with ANOVA.

RESULTS:

Forty-eight participants completed the study, generating 10,779 intracranial hemorrhage or large-vessel occlusion interpretations. With diagnostic aid, medical student accuracy improved 11.0 points (P < .001) and resident trainee accuracy showed no significant change. Intracranial hemorrhage interpretation time increased with diagnostic aid for both groups (P < .001), while large-vessel occlusion interpretation time decreased for medical students (P < .001). Despite worse performance in the detection of the smallest-versus-largest hemorrhages at baseline, medical students were not more likely to accept a true-positive artificial intelligence result for these more difficult tasks. Both groups were considerably less accurate when disagreeing with the artificial intelligence or when supplied with an incorrect artificial intelligence result.

CONCLUSIONS:

This study demonstrated greater improvement in diagnostic accuracy with artificial intelligence for medical students compared with resident trainees. However, medical students were less likely than resident trainees to overrule incorrect artificial intelligence interpretations and were less accurate, even with diagnostic aid, than the artificial intelligence was by itself.




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PD-L1+ diffuse large B-cell lymphoma with extremely high mutational burden and microsatellite instability due to acquired PMS2 mutation [RESEARCH REPORT]

We present a unique case of a single patient presenting with two mutationally distinct, PD-L1+ diffuse large B-cell lymphomas (DLBCLs). One of these DLBCLs demonstrated exceptionally high mutational burden (eight disease-associated variants and 41 variants of undetermined significance) with microsatellite instability (MSI) and an acquired PMS2 mutation with loss of PMS2 protein expression, detected postchemotherapy. This report, while highlighting the extent of possible tumor heterogeneity across separate clonal expansions as well as possible syndromic B-cell neoplasia, supports the notion that, although rare, PD-L1 expression and associated states permissive of high mutational burden (such as mismatch repair gene loss of function/MSI) should be more routinely considered in DLBCLs. Appropriate testing may be predictive of outcome and inform the utility of targeted therapy in these genetically diverse and historically treatment-refractory malignancies.





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RPG Cast – Episode 647: “Stellar Eve for When You Don’t Feel Fresh”

Kelley is creeped out by grown men in diapers. Josh can't name a kaiju that isn't Godzilla or Mothra. And Chris gets an Elden Pacifier since he's never happy.

The post RPG Cast – Episode 647: “Stellar Eve for When You Don’t Feel Fresh” appeared first on RPGamer.




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Shift Up Aiming to Release Stellar Blade for PC in 2025

Shift Up in its latest earnings report Q&A stated its goal is to release Stellar Blade for PC sometime in 2025.

"We're aiming for a 2025 release," said the developer when asked about a PC version of Stellar Blade.

"Given recent trends like Steam’s growing presence in the AAA games market and the global success of Black Myth: Wukong, we are expecting the PC version to perform even better than the console version."

The developer revealed sales for the PS5 version of Stellar Blade "have remained steady even as the initial surge has calmed."

Stellar Blade released for the PS5 in April.

Thanks, Gematsu.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/463049/shift-up-aiming-to-release-stellar-blade-for-pc-in-2025/