optimality

Quickchat Video Interview: Introducing Cadence Optimality and OnCloud for Systems Analysis and Signoff

Microwaves & RF's David Maliniak interviews Sherry Hess of Cadence about recently announced products of Optimality and OnCloud.(read more)




optimality

Incomplete Contracts, Limited Liability, and the Optimality of Joint Ownership [electronic journal].




optimality

Optimality and cooperativity in superselective surface binding by multivalent DNA nanostars

Soft Matter, 2024, 20,8515-8523
DOI: 10.1039/D4SM00704B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Christine Linne, Eva Heemskerk, Jos W. Zwanikken, Daniela J. Kraft, Liedewij Laan
Our study shows that DNA nanostars with three binding sites (ligands) can (1) bind superselectively to surfaces based on receptor density, and (2) that interactions between ligands affect the optimum number of ligands required for superselectivity.
The content of this RSS Feed (c) The Royal Society of Chemistry




optimality

Optimality for the two-parameter quadratic sieve. (arXiv:2005.03162v1 [math.NT])

We study the two-parameter quadratic sieve for a general test function. We prove, under some very general assumptions, that the function considered by Barban and Vehov [BV68] and Graham [Gra78] for this problem is optimal up to the second-order term. We determine that second-order term explicitly.




optimality

Univariate mean change point detection: Penalization, CUSUM and optimality

Daren Wang, Yi Yu, Alessandro Rinaldo.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1917--1961.

Abstract:
The problem of univariate mean change point detection and localization based on a sequence of $n$ independent observations with piecewise constant means has been intensively studied for more than half century, and serves as a blueprint for change point problems in more complex settings. We provide a complete characterization of this classical problem in a general framework in which the upper bound $sigma ^{2}$ on the noise variance, the minimal spacing $Delta $ between two consecutive change points and the minimal magnitude $kappa $ of the changes, are allowed to vary with $n$. We first show that consistent localization of the change points is impossible in the low signal-to-noise ratio regime $frac{kappa sqrt{Delta }}{sigma }preceq sqrt{log (n)}$. In contrast, when $frac{kappa sqrt{Delta }}{sigma }$ diverges with $n$ at the rate of at least $sqrt{log (n)}$, we demonstrate that two computationally-efficient change point estimators, one based on the solution to an $ell _{0}$-penalized least squares problem and the other on the popular wild binary segmentation algorithm, are both consistent and achieve a localization rate of the order $frac{sigma ^{2}}{kappa ^{2}}log (n)$. We further show that such rate is minimax optimal, up to a $log (n)$ term.




optimality

On the Optimality of Randomization in Experimental Design: How to Randomize for Minimax Variance and Design-Based Inference. (arXiv:2005.03151v1 [stat.ME])

I study the minimax-optimal design for a two-arm controlled experiment where conditional mean outcomes may vary in a given set. When this set is permutation symmetric, the optimal design is complete randomization, and using a single partition (i.e., the design that only randomizes the treatment labels for each side of the partition) has minimax risk larger by a factor of $n-1$. More generally, the optimal design is shown to be the mixed-strategy optimal design (MSOD) of Kallus (2018). Notably, even when the set of conditional mean outcomes has structure (i.e., is not permutation symmetric), being minimax-optimal for variance still requires randomization beyond a single partition. Nonetheless, since this targets precision, it may still not ensure sufficient uniformity in randomization to enable randomization (i.e., design-based) inference by Fisher's exact test to appropriately detect violations of null. I therefore propose the inference-constrained MSOD, which is minimax-optimal among all designs subject to such uniformity constraints. On the way, I discuss Johansson et al. (2020) who recently compared rerandomization of Morgan and Rubin (2012) and the pure-strategy optimal design (PSOD) of Kallus (2018). I point out some errors therein and set straight that randomization is minimax-optimal and that the "no free lunch" theorem and example in Kallus (2018) are correct.




optimality

Multichannel Management: A Normative Model Towards Optimality / Gottfried Gruber

Online Resource