mon Latest NFL playoff projections: Seahawks, Vikings can shake things up on Monday Night Football By www.washingtonpost.com Published On :: Mon, 10 Dec 2018 14:50:47 +0000 The two teams in control of the NFC's wild-card slots battle head-to-head, while the rest of the NFL playoff picture got much clearer despite four of the AFC’s top teams losing. Full Article
mon Dock workers in Belgium are wearing monitoring bracelets that enforce social distancing — here's how they work By feedproxy.google.com Published On :: Sat, 09 May 2020 09:01:00 -0400 Dockworkers in Belgium are wearing bracelets to enforce social distancing. The bracelets were already used to detect if someone fell into the water, but now they will sound an alarm if workers get to close to each other. Manufacturers say there is no privacy issue and the bracelets don't track workers' locations, despite concerns. Visit Business Insider's homepage for more stories. Quarantine and social distancing are going high-tech as countries and companies embrace wearables. In Antwerp, Belgium, dockworkers are instructed to wear bracelets that enforce social distancing rules while they work. Europe, where more than 100,000 people have died from COVID-19, is slowly starting to reopen in some places. Stay at home orders are expiring in many countries, while nonessential travel has stopped across the EU, and countries look towards the summer to anticipate what kind of travel might be possible. People are beginning to go back to work, which in some sectors means inevitable close contact, especially in many essential jobs. Social distancing bracelets in Belgium are one idea bing tested to see what the future of work might look like after coronavirus. Here's how it works. SEE ALSO: People arriving in Hong Kong must wear tracking bracelets for 2 weeks or face jail time. Here's how they work. The black, plastic bracelets are worn on the wrist like a watch. They're made by Belgian company Rombit, which says that they are "a fully integrated personal safety and security device, specifically designed for highly industrial environments." Source: Romware Rombit already made bracelets useful in the port setting, which could be used to call for help if a worker fell into the water or another accident occurred. Europe is slowly starting to go back to work, but fears of a second wave are making officials cautious. Contact tracing is one solution being explored around the world, and the manufacturers of the bracelet believe it could also be used for contact tracing. Source: The Associated Press European health guidances say to wash hands, wear masks, and keep at least 1.5 meters, or about five feet, apart. When two workers are less than five feet apart, the bracelets will sound warnings. Rombit CEO John Baekelmans told Reuters that the bracelets won't allow companies to track employees' locations, because the devices are only connected to each other. He says there is no central server. Source: Reuters Workers in the control tower will be the first to test the bracelets early this month. Then, the Port of Antwerp will likely expand the devices to tug boat workers. Baekelmans told Reuters that Rombit already had hundreds of requests in 99 countries, and is hoping to ramp up production to 25,000 in a few weeks. Full Article
mon Goldman Sachs is going through a huge transformation under CEO David Solomon By feedproxy.google.com Published On :: Sat, 09 May 2020 11:19:00 -0400 The storied investment bank is seeing leadership shakeups under CEO David Solomon and a slew of partner departures. Goldman has been moving away from high-risk businesses like trading and is making pushes into more stable areas like consumer lending, wealth management, and transaction banking. There have been big cultural changes, too. Solomon is looking to create a more transparent workplace, while new tech execs are taking cues from Silicon Valley heavy-hitters. At Business Insider, we are closely tracking the latest developments at Goldman. You can read all of our Goldman coverage on BI Prime. Storied Wall Street bank Goldman Sachs is going through some massive changes under CEO David Solomon. It's taken big steps involving transparency and inclusion to change up its culture. It has seen a slew of partner departures — many in the securities division. And it's making big pushes into businesses like wealth management and transaction banking. The latest people moves Goldman Sachs just hired Kurt Hoffman, an expert in distressed situations and bankruptcy, to join a trading unit known for some of the bank's most lucrative deals Goldman Sachs' top tech exec explains how a fresh slew of senior hires are transforming the bank's approach to building products Read the full memo Goldman Sachs just sent naming 4 execs to lead its private-equity investments across the merchant-banking division Culture and talent Read the full memo Goldman Sachs just sent to staff announcing its new head of regulatory affairs. The former White House counsel will be tasked with helping clean up the bank's 1MDB drama. Goldman Sachs just hired 2 senior recruiting execs focused on luring top talent from other firms —and it's a huge departure from the firm's traditional promote-from-within mentality Read the full memo David Solomon just sent to 38,000 Goldman Sachs employees explaining why he's moving his management team out of stuffy offices and into open seating Goldman Sachs CEO David Solomon and his management team are ditching their stuffy offices and moving to an open floor plan closer to the people so they can feel the buzz of New York headquarters Goldman Sachs just unveiled a new gender pronouns initiative as part of a broader inclusion push at the Wall Street firm Read the memo Goldman Sachs just sent to its employees unveiling a new pronouns initiative Coronavirus response Inside a 38,000-person remote work rollout at Goldman Sachs: sleepless nights, assembly lines, and an Amazon-like hub on a Manhattan trading floor How a massive New York hospital secured 130,000 N95 masks from China with help from a senior partner at Goldman Sachs, private jets, and a call to Warren Buffett Goldman Sachs CEO David Solomon just sent a firm-wide voicemail about the coronavirus crisis. Here's what he told employees. Goldman Sachs and Bank of America just updated their WFH policies — again. Here's what they're telling employees about the latest steps aimed at combating the spread of coronavirus. Read the full memo Goldman Sachs top brass just sent detailing the firm's coronavirus contingency plans, including separating employees into 'blue' and 'white' teams to alternate working from the office and home Consumer push, transaction banking, wealth management Goldman Sachs just announced its first partnership for transaction banking as it looks to build a new $1 billion business moving money around the world Goldman Sachs is sending much less mail to potential Marcus customers. A senior exec lays out the reason why. A Goldman Sachs exec explains why the bank isn't sweating concerns over the Apple Card's profitability A Wall Street firm crunched the numbers around how much Apple will make from its new credit card with Goldman Sachs Here's why Goldman Sachs just did its biggest deal in nearly 20 years as part of a pivot to less wealthy clients Goldman Sachs execs are opening up about their plans for Marcus, and they think it can do to banking what iTunes did to the music industry Goldman Sachs' partnership with Apple could move it a step closer to being 'a bank branch in your pocket' Human resources is the next battleground for Wall Street wealth advisers as Morgan Stanley and Goldman Sachs jockey over new turf Goldman Sachs has a novel method for predicting the next economic slump, and it's at the heart of its hot new business Technology JPMorgan and Goldman Sachs are finally beginning to embrace fintech startups. Here's how they test the waters before committing to working with them. We talked to the execs behind Bloomberg's new data partnership with Goldman Sachs. Here's why they think it's a sign of Wall Street's future. Goldman Sachs is putting its own Marquee app on Amazon's cloud in a pitch to lure more fintech developers Goldman Sachs is embracing open-source code and its chief data officer says it's part of a "new world" of software Read the memo the new Goldman tech chief sent to the firm's 9,000-plus engineers where he urges them to ditch presentations in favor of Amazon's famous narratives A new Goldman Sachs tech exec hired from Amazon is taking a page from the Jeff Bezos playbook by urging engineers to ditch PowerPoint and write memos Goldman Sachs' new CTO shares his strategy for attracting outside developers to work more closely with the bank, giving a glimpse into the future of how Wall Street will work A Verizon executive is joining Goldman Sachs as chief technology officer as the Wall Street bank reshuffles its ranks Marty Chavez is retiring from Goldman Sachs. We chatted with him about the bank's tech transformation, why now is the right time for him to step down, and what he's planning next. Goldman Sachs tech guru Marty Chavez is retiring from the bank Goldman Sachs' CEO just warned that the bank's big tech bets might not pay off as quickly as people hope Goldman Sachs is scrapping a homegrown email app it once touted — and it's a sign the bank is moving away from building tech in house Goldman Sachs is exploring plans to create a Netflix for data, and it marks a new frontier for Wall Street Goldman Sachs' internal idea factory hatched a plan for the Google of Wall Street, and it's now looking for the next big thing to disrupt the bank Goldman Sachs' big bet on the future of Wall Street had a rocky start. Here's the inside story of the bank's struggle to grow its next business and an exclusive look at its plans Trading Bank of America is shaking up its global markets division and poached a Goldman Sachs exec to fill a key new role Goldman Sachs' massive quant business now rivals AQR and Two Sigma. We talked to the bank's top quant about asset growth, finding data sources, and why critics of computerized trading are wrong. Goldman Sachs' CEO tells us the bank is winning over quant clients. That helped it outpace rivals like JPMorgan last quarter. Goldman Sachs is cutting about 5% of sales and trading staff after senior equities leaders delivered a tough town-hall talk Goldman Sachs is moving away from a tool championed by its former CFO as it pushes its traders to see clients where they once saw quick wins Goldman Sachs is shuffling its top stock trading executives as the business tries to claw back market share from Morgan Stanley and JPMorgan Goldman Sachs's bond trading unit is still trying to find its way — and it represents a key challenge for new CEO David Solomon Alternatives Read the full memo Goldman Sachs just sent naming 4 execs to lead its private-equity investments across the merchant-banking division Goldman Sachs is making targeted hires for a 'storefront' for alternative investments that's modeled after firms like KKR and Blackstone Goldman Sachs' push into private equity is ruffling feathers at Blackstone — and it might be a sign of big client skirmishes to come Goldman Sachs execs are jockeying for control of the firm's lucrative private investing units after a plan to merge it — and the stakes couldn't be higher Meet the Goldman Sachs execs tasked with building the firms' new Blackstone-esque private-investing unit — and pumping up the bank's flagging stock price 'It's good to be Rich': Meet the Goldman Sachs banker who has built a private investing empire that goes head-to-head with Blackstone — and you've probably never heard of him Goldman Sachs is considering a shakeup of its alternative investing units as part of a plan to simplify the bank's strategy Deals Goldman Sachs is assembling a team of senior bankers focused on middle-market private equity. Here are the key hires and the playbook they'll use to land new clients. Goldman Sachs unloaded some of its WeWork shares before its investment bankers pitched investors on what it once considered a $60 billion-plus IPO Goldman Sachs just revealed it sold part of its Uber stake to SoftBank and it helped boost a $4.5 billion business A senior Goldman Sachs fintech banker was about to join JPMorgan — but then got lured back —and it's another sign of the fierce battle for M&A talent Goldman just promoted a star tech banker close to Tesla and Microsoft to co-head one of its most profitable businesses, as incoming CEO Solomon makes his mark Goldman Sachs just announced a shakeup of its leadership — and it signals the rise of bankers over traders A tug-of-war between Goldman Sachs and JPMorgan over a top banker highlights Wall Street's $1 trillion battleground Investor day 2020 Inside Goldman Sachs' first investor day, where avocado toast and crab apples were served with tech talk, 3-year plans, and a surprising trading mea culpa Goldman Sachs just revealed a new wealth brand at its first-ever investor day. It shows how the bank is trying to reshape its strategy — and image. Goldman Sachs just unveiled hundreds of slides laying out the future of the company. Here are the 10 crucial slides that show how it plans to transform into a bank for everyone. Goldman Sachs is rethinking how it makes private-equity bets with its own money – and one analyst thinks that shift will be a big driver of its stock price Careers Goldman Sachs is now hiring high-school graduates for roles in Salt Lake City, one of the company's 'high value' locations Goldman Sachs has lost at least 54 partners since David Solomon became CEO. We're keeping a running list — and compiling details from insiders about how the exits are being celebrated. Read the full memo Goldman Sachs' top brass just sent to staff announcing 2 heads of the bank's private-investing arm are out as it's gearing up to raise billions 2 coheads of Goldman Sachs' private-investing business are retiring, in a blow to David Solomon's fundraising plans A Goldman Sachs partner who just resigned is leaving behind a job overseeing $2 billion for a London VC with a leading stake in neobank Revolut Read the memo announcing the departure of Adam Korn, the Goldman Sachs exec who was 'instrumental in building and championing' innovations like the bank's Marquee platform Another Goldman Sachs partner is out. HR chief Dane Holmes is the latest key player to leave the Wall Street bank in a matter of days. Goldman Sachs is offering buyouts to encourage partners to leave as CEO David Solomon works to shrink one of the most elite clubs on Wall Street Goldman Sachs is making renewable energy a big priority based on its hiring strategy. It's a sign that its ideas incubator is working. The David Solomon era at Goldman Sachs kicked off with 43 words Lloyd Blankfein would never say Goldman Sachs CEO David Solomon shares his best leadership advice Goldman Sachs is shaking up the way it stocks one of the most elite clubs on Wall Street — and it shows how banks are back to making money again Goldman Sachs' 1MDB problems are eating into employee morale, and insiders worry the firm will use its legal woes as an excuse to scrimp on bonuses Goldman Sachs is about to move dozens of jobs out of pricey New York to Utah as Wall Street turns to cheaper cities Join the conversation about this story » NOW WATCH: A cleaning expert reveals her 3-step method for cleaning your entire home quickly Full Article
mon Monica Lewinsky jokes about the worst career advice she’s ever been given By www.washingtonpost.com Published On :: Mon, 15 Jul 2019 19:29:11 +0000 The former scandal figure is mining what was a traumatic experience for some dark humor. Full Article
mon Dan Crenshaw defends Ricky Gervais’s Golden Globes monologue: ‘He’s illuminating their hypocrisy.’ By www.washingtonpost.com Published On :: Tue, 07 Jan 2020 23:18:17 +0000 The Republican congressman chastised entertainment culture for being "divisive." Full Article
mon PayPal to TransferWise – Cheap International Money Transfer By feedproxy.google.com Published On :: Sat, 23 Nov 2019 02:57:32 +0000 While we have covered a number of tutorials on PayPal in the past, in this tutorial we will look at a relatively new platform that goes by the name of TransferWise. I will discuss what TransferWise is and how you can use it with your PayPal account. I will also cover why this platform is […] The post PayPal to TransferWise – Cheap International Money Transfer appeared first on Tips and Tricks HQ. Full Article Shop Admin Tips Tech Tips Accept Money Online Money Online Payments Payment Processor Paypal PayPal Tutorials Receive Money save money Transfer Money Transferwise
mon How to Send Money Overseas with TransferWise By feedproxy.google.com Published On :: Tue, 10 Dec 2019 03:30:18 +0000 The days of your family member sending you money in an envelope from overseas are decreasing due to the risk of this money getting lost in transit or removed from your letterbox before you’ve arrived home. While many merchants and everyday people are sending money to family and friends abroad using PayPal, TransferWise is, in […] The post How to Send Money Overseas with TransferWise appeared first on Tips and Tricks HQ. Full Article Tech Tips Video Tutorial Online Money Overseas Transfer Receive Money save money Transfer Transfer Money Transferwise
mon A question missing from the health-care debate: Will doctors make less money? By www.washingtonpost.com Published On :: Thu, 01 Aug 2019 23:01:07 +0000 Democratic candidates need to show their math. Full Article
mon oscon: Easily Invoke Common Protocols with Twisted - Spin up Python-friendly services with 0 lines of code http://t.co/29oTkk0isW By twitter.com Published On :: Tue, 11 Jun 2013 16:40:44 +0000 oscon: Easily Invoke Common Protocols with Twisted - Spin up Python-friendly services with 0 lines of code http://t.co/29oTkk0isW Full Article
mon Fin24.com | ADvTech expects profit spike after Monash SA acquisition By www.fin24.com Published On :: Thu, 05 Mar 2020 08:41:51 +0200 ADvTECH attributed the expected rise in earnings to one-off transactions including "bargain purchase gains" arising from the Monash SA acquisition, foreign exchange movements and insurance proceeds related to a previously reported fraud event. Full Article
mon 7 Common Negotiation Mistakes to Avoid at all Costs By feedproxy.google.com Published On :: Thu, 02 Jan 2020 16:00:27 +0000 Many often consider negotiation an arduous task, as it involves having conversations with people, where both parties are doing their best to protect personal interests. Going over negotiations while maintaining relationships remains relevant to businesses and investments. It hardly comes easy to conclude a negotiation that keeps both parties happy, while overlooking small processes may […] The post 7 Common Negotiation Mistakes to Avoid at all Costs appeared first on ReadWrite. Full Article Entrepreneurs Marketing Negotiation Negotiation Agreement negotiation process
mon German Rights Holders Go After 300,000 P2P Users Per Month By feedproxy.google.com Published On :: Tue, 31 May 2011 12:11:01 -0700 German content owners have been busy pursuing alleged infringers: Local ISPs have to hand out around 300,000 names and addresses of file sharers caught in the act ever month, according to data from a German industry association. Will we see similar numbers in the U.S. soon? Continue reading on GigaOM Broadband. Tags: Germany, lawsuits, gigaom Full Article Lawsuits
mon velocityconf: @da3mon Sorry! We were just doing some followup with past Velocity attendees. Sorry to intrude. No harm intended. :-( By feedproxy.google.com Published On :: Thu, 23 May 2013 20:03:49 +0000 velocityconf: @da3mon Sorry! We were just doing some followup with past Velocity attendees. Sorry to intrude. No harm intended. :-( Full Article
mon News24.com | Covid-19: Five new cases among prisoners, 3 officials recovered By www.news24.com Published On :: Sat, 09 May 2020 11:26:03 +0200 Five new Covid-19 cases have been recorded among prison inmates and three Department of Correctional Services officials have recovered. Full Article
mon Cool Start-up Interview Series – Mondly Languages By feedproxy.google.com Published On :: Thu, 28 Mar 2019 00:00:00 +0000 We’ve recently had the pleasure to chat with Andrei Nastasie, the affiliate program manager at Mondly Languages, an innovative language learning app that incorporates native language recordings, augmented reality and virtual reality to help people learn new languages. In this interview, he shares how Mondly started out, what it has been up to and what’s next for this creative company. Full Article
mon AT#67 - Travel to Edmonton and Jasper, Alberta Canada By traffic.libsyn.com Published On :: Mon, 20 Nov 2006 03:40:00 +0000 Edmonton and Jasper, Alberta Canada Full Article
mon AT#101 - Travel to The French Riviera (Nice, Cannes, Antibes) and Monaco By traffic.libsyn.com Published On :: Sun, 12 Aug 2007 19:40:00 +0000 The French Riviera (Nice, Cannes, Antibes) and Monaco Full Article
mon AT#111 - Travel to Mongolia By traffic.libsyn.com Published On :: Sat, 27 Oct 2007 17:02:00 +0000 Mongolia Full Article
mon AT#232 - Travel to Montenegro By europe.amateurtraveler.com Published On :: Sat, 15 May 2010 14:00:00 +0000 The Amateur Traveler talks to photographer Ralph Velasco about a trip to the very new country of Montenegro. When Ralph visited the country it was the newest country on the planet after it split off of Serbia. This mountainous country boasts the southern most fjords in Europe, old walled Venetian towns, fortresses, island churches, hikes, rafting, and some wonderful photography. Ralph stayed on the coast and visited the coastal cities of Kotor, Budva and Perast among others. Full Article
mon AT#244 - Travel to Montpellier and the Languedoc Region of France By europe.amateurtraveler.com Published On :: Sat, 21 Aug 2010 14:00:00 +0000 The Amateur Traveler talks to Christine Cantera about her time living in the Languedoc region of France in the city Montpellier. Montpellier is sometimes called the San Francisco of France. Christine shares with us a few thoughts about cafes, bars, which museums are worth it (and which aren’t), beaches, fortified cities, when to visit, and the one day of the year when nobody in France gets any work done. She discusses what are her favorite 3 places to see in Languedoc including one seaside town that still has jousts but with a very nautical twist.NewsSouthwest attendant takes baby after slap from motherAmerican Airlines to Charge for Front-Row SeatsNursing at SeaShow NotesFrance Travel GuideMontpellierLanguedocJardin des plantes de MontpellierLe Petit Train Touristique du Centre HistoriqueLanguedoc wineLe Jardin du Champs de MarsPaparazziLa Dolce VitaAigues-MortesCarcassonneParc naturel régional de CamargueMusee FabreAntigone DistrictPalavas-les-FlotsSèteNîmesBeaujolais nouveauBar le Saint-RochMissExpatria’s photostreamCommunity Sam was looking for a show on MaltaDon't use the first LukeDon’t use the first Luke Full Article
mon AT#257 - Travel to Glacier National Park and Western Montana By usa.amateurtraveler.com Published On :: Sat, 04 Dec 2010 15:00:00 +0000 The Amateur Traveler talks to Karl Anders who returns to the show to talk about travel to Western Montana and in particular to the majestic Glacier National Park. Karl encourages us to drive the Going to the Sun Highway but then to get off the blacktop and hick some of the back country of the park (preferably in a group large enough to discourage the curiosity of bears). He describes some of his favorite hikes such as the trail to Hidden Lakes. Glacier is often rated as one of the top places in the United States to hike or backpack. The valleys of Glacier are carved by glacial activity although there aren't as many glaciers still in the park. Karl also talks about some nearby destinations like the National Bison Refuge, Bitterroot Valley and nearby Missoula with its museum to Smokejumpers. Full Article
mon AT#332 - Trekking Around Mont Blanc, France By europe.amateurtraveler.com Published On :: Sat, 07 Jul 2012 12:30:00 +0000 The Amateur Traveler talks to Marc Barach about his recent trek around Monte Blanc. Hiking around the giant mountain on the tour Monte Blanc took him through portions of France, Italy and Switzerland. Full Article
mon AT#340 - Travel to the Microstates of Europe (Andorra, Liechtenstein, Monaco, San Marino) By europe.amateurtraveler.com Published On :: Sat, 08 Sep 2012 21:54:00 +0000 The Amateur Traveler talks to to Gary Arndt about the 4 micro-states in Europe: Andorra, Liechtenstein, Monaco, San Marino. "They all have very unique histories and the one thing that they are all very small" Full Article
mon AT#407 - Travel to Montana By usa.amateurtraveler.com Published On :: Sat, 15 Feb 2014 21:28:31 +0000 Hear about travel to Montana as the Amateur Traveler talks to Donna Hull from MyItchyTravelFeet.com. Donna and her husband visited Montana in 2001 as part of a National Park tour and fell in love with the Big Sky state. Finally in 2010 they moved to the Bitterroot Valley of Montana, the so called “banana belt” of Montana. They had planned to live there only in the Summer but did not want to leave when the end of Summer came. Full Article
mon AT#440 - Travel to Vermont By usa.amateurtraveler.com Published On :: Sun, 19 Oct 2014 01:15:01 +0000 Hear about travel to Vermont as the Amateur Traveler talks to Dana Freeman of findandgoseek.net about her adopted home state. Dana has lived in Vermont for 14 years and someday her children's children may be Vermonters. Full Article
mon AT#524 - Hiking the Peaks of the Balkans (Albania, Kosovo, Montenegro) By europe.amateurtraveler.com Published On :: Sat, 13 Aug 2016 14:00:00 +0000 Hear about hiking the Peaks of the Balkans trail in Albania, Kosovo, and Montenegro as the Amateur Traveler talks to Dan and Audrey from uncorneredmarket.com about this off the beaten track route in Europe. Full Article
mon AT#526 - Travel to Richmond, Virginia By usa.amateurtraveler.com Published On :: Sat, 27 Aug 2016 14:00:00 +0000 Hear about travel to Richmond, Virginia as the Amateur Traveler talks to Becky Pekora from TheGirlAndGlobe.com about her adopted hometown. Full Article
mon AT#603 - Travel to Mongolia By asia.amateurtraveler.com Published On :: Sat, 14 Apr 2018 14:00:00 +0000 Hear about travel to Mongolia as the Amateur Traveler talks to Patricia from zewanderingfrogs.com about travel to this remote destination. Full Article
mon AT#604 - Travel to Montenegro By europe.amateurtraveler.com Published On :: Sat, 21 Apr 2018 14:00:00 +0000 Hear about travel to Montenegro as the Amateur Traveler talks to Gary Arndt from everything-everywhere.com about his recent trip to this beautiful mountainous country in the Balkans. Full Article
mon AT#662 - Travel to the Piedmont Region of Italy By amateurtraveler.com Published On :: Sat, 29 Jun 2019 15:10:41 +0000 Hear about travel to Barolo and the Piedmont region of Italy as the Amateur Traveler talks to Betsy and Greg Ball from eurotravelcoach.com about this wine region that they love. Full Article
mon ___-of-the-Month Clubs By tracking.feedpress.it Published On :: Fri, 24 May 2019 07:01:07 +0000 The Book-of-the-Month Club is still going strong after more than 90 years, despite the rise and fall of mega-bookstores (and the advent of Amazon.com). But that's not all: you can get a monthly subscription to just about anything. Full Article Interesting Thing
mon New Study Confirms We Were Right: Reading, Math Scores Have Collapsed Thanks to Obama, Common Core By www.westernjournal.com Published On :: Sat, 09 May 2020 14:42:18 +0000 Conservatives had this Common Core thing all wrong, it was said. We’d be proven wrong by history. Common Core, pushed by President Barack Obama, was going to work. It wasn’t like all the other liberal education plans. A new study by the Pioneer Institute reveals that, no, we were right all along. The study, released… The post New Study Confirms We Were Right: Reading, Math Scores Have Collapsed Thanks to Obama, Common Core appeared first on The Western Journal. Full Article Commentary Barack Obama Common Core Department of Education DOE Education Obama administration
mon 10-Month-Old Gets Heartwarming Celebration from Hospital Staff After Finishing Chemotherapy By www.westernjournal.com Published On :: Sat, 09 May 2020 14:59:40 +0000 As confetti floated through the air, a baby boy and his family celebrated his final chemotherapy treatment in time to go home before his first birthday. According to KSAZ, young Aaron has been battling a rare form of cancer called acute megakaryoblastic leukemia since he was four months old. Aaron was a patient at Duke… The post 10-Month-Old Gets Heartwarming Celebration from Hospital Staff After Finishing Chemotherapy appeared first on The Western Journal. Full Article Lifestyle baby Cancer children family Health medical North Carolina Uplifting
mon With Debate Months Away, It’s Clear Biden Isn’t Ready for a 1-on-1 with Trump By www.westernjournal.com Published On :: Sat, 09 May 2020 15:22:45 +0000 In just under five months, both President Donald Trump and former Vice President Joe Biden will, one assumes, step onto a debate stage at the University of Notre Dame in South Bend, Indiana. It’s one heck of an assumption, and for more reasons than one. We don’t know if there are going to be debates… The post With Debate Months Away, It’s Clear Biden Isn’t Ready for a 1-on-1 with Trump appeared first on The Western Journal. Full Article Commentary 2020 election Coronavirus Donald Trump Joe Biden Presidential Debate US News
mon Zoom Is YouTube, Instagram, and WhatsApp – All in Two Months. By feedproxy.google.com Published On :: Thu, 30 Apr 2020 03:10:56 +0000 If you’ve read Shoshana Zuboff’s Surveillance Capitalism, you likely agree that the most important asset for a data-driven advertising platform is consumer engagement. That engagement throws off data, that data drives prediction models, those models inform algorithms, those algorithms drive advertising engines, and those engines drive revenue, which drives profit. And profit, of course, drives … Continue reading "Zoom Is YouTube, Instagram, and WhatsApp – All in Two Months." Full Article Internet Big Five Joints After Midnight & Rants Media/Tech Business Models The Web As Platform advertising Capitalism data facebook Google saas tech zoom
mon Loosening restrictions could mean huge increase in Montreal COVID-19 deaths: report By montreal.ctvnews.ca Published On :: Sat, 9 May 2020 08:35:00 -0400 By easing distancing measures, the Greater Montreal area could experience a substantial increase in the number of deaths per day due to the coronavirus, according to a new document published by the Institut national de santé publique du Québec (INSPQ) in collaboration with experts from Laval University. Full Article
mon 10 of the best fitness trackers for monitoring heart rate By feedproxy.google.com Published On :: Sat, 27 Oct 2018 09:00:00 +0000 BEST FITNESS TRACKER DEALS: Fitbit - Charge 3 Activity Tracker + Heart Rate — $99.95 (save $30) Garmin - Forerunner 645 Music GPS Heart Rate Monitor Running Watch — $449.99 3Plus - HR Activity Tracker + Heart Rate — $49.99 Wellness is a buzzy word lately. Over the past few years, we’ve seen a surge in all things health, wellness, and spirituality. Juice bars are popping up, boutique studios are becoming more accessible, and essential oils are chilling us out. Self-care is becoming more of the norm too, but amidst all this hype, it can be challenging to find the right routine that promotes good exercise, sleep, vitals, and mindset. Read more...More about Apple Watch, Fitness Trackers, Smart Watch, Heart Rate Monitor, and Mashable Shopping IMAGE: Amazon BEST OVERALL Apple Watch Series 4 Take heart monitoring to the next level with the Apple Watch Series 4's amazing EKG feature and FDA-cleared precision. Warranty: 90 days with Apple Care+ Smartphone compatibility: Yes Battery life: 22 hours Weight: 1.06 oz What you'll get: A case, band, 1m magnetic charging cable, and 5W USB Power Adapter $236.98 from Amazon IMAGE: Amazon BEST BANG FOR YOUR BUCK Polar A370 Fitness Tracker Smartphone compatibility and a variety of wellness features makes Polar’s A370 Fitness Tracker our top choice for health management. Warranty: 2 years Smartphone Compatibility: Yes Battery life: 4 days Weight: 13.8 ounces What you’ll get: A Polar A370 Fitness Tracker, a band, a charging cable, and a manual $114.99 from Amazon IMAGE: Amazon EASIEST TO USE Fitbit Charge 3 Fitness Activity Tracker The new Charge 3 provides no-fuss wellness features to take your daily sleep, workouts, and vitals to the next level. Warranty: 45-day guarantee and 1 year warranty Smartphone compatibility: Yes Battery life: 7 days Weight: 4.8 ounces What you’ll get: A Fitbit Charge 3, classic wristbands (both small & large), and a charging cable $119.03 from Amazon IMAGE: Best Buy BEST FOR ATHLETES Garmin Forerunner 735XT Smartwatch With sport-specific settings, advanced training feedback, and a connected app, Garmin’s Forerunner 735XT Smartwatch is the perfect fitness companion for athletes. Warranty: 1 year Smartphone compatibility: Yes Battery life: 1 day Weight: 1.4 ounces What you’ll get: A Garmin Forerunner 735XT Smartwatch, a charging/data clip, and a manual $349.99 from Best Buy IMAGE: Amazon BEST FOR TECH ENTHUSIASTS Nokia Steel HR Hybrid Smartwatch Add some tech to your exercise regimen with the Nokia’s Steel HR Hybrid with Alexa integration and three different heart monitor modes. Warranty: 1 year Smartphone compatibility: Yes Battery life: 25 days Weight: 8.2 ounces What you’ll get: A Nokia Steel HR Hybrid Smartwatch and a CR2 battery $199.95 from Amazon IMAGE: Amazon BEST FOR WATER SPORTS Garmin vívoactive 3 Warranty: 1 year Smartphone compatibility: Yes Battery life: 10 days Weight: 1.44 ounces What you'll get: A vívoactive 3 Fitness Tracker, a charging/data cable, and manuals $319.99 from Amazon IMAGE: Amazon BEST FOR STYLE Motiv Ring Warranty: 45-day guarantee and 1-year warranty Smartphone compatibility: Yes Battery life: 3 days Weight: 1.6 ounces What you'll get: A Motiv Ring, sizing set, and two slim charging docks $199.99 from Amazon IMAGE: Amazon BUDGET PICK Microtella Fitness Tracker Microtella’s Fitness Tracker is affordable, monitors your heart rate, and comes with 14 different fitness settings for personalized workout stats. Warranty: None Smartphone Compatibility: Yes Battery life: 7 days Weight: 4 ounces What you’ll get: A Microtella Fitness Tracker, a band, and a USB charger $39.99 from Amazon IMAGE: Amazon BEST OF BOTH WORLDS Samsung Galaxy Fit The perfect midpoint between the Fitbit and Apple Watch, the Samsung Galaxy Fit is great for tracking your high-intensity activities and for managing your daily life. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 7 days Weight: 3.2 ounces What you'll get: Samsung Galaxy Fit, charging cable, manuals $79 from Amazon IMAGE: Amazon BEST ON-SCREEN WORKOUTS Fitbit Versa The Fitbit Versa is best for those who need some extra guidance in the gym, and thanks to its comprehensive array of on-screen workouts, you'll get exactly that. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 4 days Weight: 5.12 ounces What you'll get: Fitbit Versa, charging cable, manuals $199.95 from Amazon IMAGE: Amazon BEST BATTERY LIFE Wahoo TICKR Won't take up precious real estate on your wrists and will provide personalized heart rate training, as well as an unbeatable 12-month battery life. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 1 year Weight: 2.4 ounces What you'll get: Wahoo TICKR, battery, manuals $45.94 from Amazon Full Article Apple Watch Fitness Trackers Smart Watch Heart Rate Monitor Mashable Shopping
mon Apple to begin reopening U.S. stores this month By feedproxy.google.com Published On :: Fri, 08 May 2020 23:46:02 +0000 Apple, dear reader, has been missing you — and it's banking on the fact that you've been missing the opportunity to touch its products before you buy them, too. In an effort to ease this assuredly mutual feeling of longing, the company confirmed on Friday plans to begin reopening some of its U.S. stores as early as MondayApple had been aiming for a May reopening for some time, but now it's official. So reports CNBC, which notes that the openings are, for now, limited to stores in four states: Idaho, South Carolina, Alabama, and Alaska. "We've missed our customers and look forward to offering our support," an Apple spokesperson told CNN Business. Read more...More about Apple, Coronavirus, Tech, and Big Tech Companies Full Article Apple Coronavirus Tech Big Tech Companies
mon Send love to faraway friends and family with this video montage app By feedproxy.google.com Published On :: Sat, 09 May 2020 09:00:00 +0000 TL;DR: Give a meaningful gift during these difficult times with a Tribute Video Montage for $64.99, a 34% saving as of May 9. A Zoom happy hour only goes so far. If you're looking for a way to celebrate and send affection to your loved ones, regardless of the reason, check out Tribute Video Montage as an alternative to those wonky (and sometimes awkward) video calls. Sending a Tribute might just be one of the best morale-boosting presents you can send during these trying times. It's a way for friends and family to share their love and appreciation for someone they want to celebrate, whether for a major milestone, like a 50th anniversary or 30th birthday or just because. The platform is super easy to use and breaks a 10-hour process down to just 10 minutes. Read more...More about Apps And Software, Mashable Shopping, Tech, and Consumer Tech Full Article Apps And Software Mashable Shopping Tech Consumer Tech
mon Suspicious package found in north Edmonton deemed non-threatening By edmonton.ctvnews.ca Published On :: Sat, 9 May 2020 10:22:00 -0600 A transit centre in north Edmonton was evacuated for about two hours Saturday morning due to a suspicious package. Full Article
mon Most Realtors® Don’t Expect Steep Price Declines in Next 12 Months By feedproxy.google.com Published On :: Mon, 27 Apr 2020 17:33:19 +0000 Most Realtors® Don’t Expect Steep Price Declines in... Among the 4,063 respondents, 23% expect prices to remain stable, 38% expect prices to increase, and 40% expect prices to fall. By: Scholastica (Gay) Cororaton Full Article
mon 9 Frugal Tips for Families to Save Money By feedproxy.google.com Published On :: Wed, 29 Apr 2020 13:14:49 +0000 Family is an integral part of any person’s life. When we live with our families, it’s either we’re dependent on somebody or somebody is dependent on us. Many conflicts arise in a family due to improper finance management. When you have a family, you might often come across situations where you might feel there is […] The post 9 Frugal Tips for Families to Save Money appeared first on Dumb Little Man. Full Article Home Money
mon AK Monthly Recap: March 2020 By feedproxy.google.com Published On :: Tue, 07 Apr 2020 10:00:00 +0000 Before I start recapping the month, let me begin with a greeting: “Hey, Kate from the future! Hey, people who were curious! I knew you’d look up this post! How are you doing? By the way, just how long is this going to last?!” Because this is the recap for March 2020 — a month … AK Monthly Recap: March 2020 Read More » The post AK Monthly Recap: March 2020 appeared first on Adventurous Kate. Full Article Blog Monthly Recap
mon AK Monthly Recap: April 2020 By feedproxy.google.com Published On :: Wed, 06 May 2020 22:29:26 +0000 Is it just me, or did this month majorly speed up? March 2020, the month that coronavirus ramped up enormously, was the longest month of my life. I know it was for many of you, too. By comparison, April seemed to go by in 10 days. This month the hardest decision of my life — … AK Monthly Recap: April 2020 Read More » The post AK Monthly Recap: April 2020 appeared first on Adventurous Kate. Full Article Blog Monthly Recap
mon Guatemalan Black Howler Monkey By feedproxy.google.com Published On :: Fri, 03 Jul 2015 17:05:00 +0200 The endangered Guatemalan Black Howler (Alouatta pigra) (sometimes called the Yucatan Howler or Yucatan Black Howler) is one of many species of howler monkey, which is what is known as a ‘New World’ monkey. Its range is throughout the Yucatan Peninsula, and includes the areas of Mexico, Belize, and of course Guatemala. The Guatemalan Black Howler prefers to live in very lush areas, mostly sticking to all types of rain forests such as the semi-deciduous, lowland and evergreen. Of its cousins and relatives, the Guatemalan Black Howler is the largest, and is also one of the largest ‘New World’ monkeys (which include marmosets, owl monkeys, sakis, spider, and woolly monkeys). It weighs in at 25 lbs on average in males (11-12 kg) and 14 lbs for the females (6-7 kg). Their fur is usually black and their tails are very long, and prehensile (meaning it can grab and be used to hang from branches with). They also have specialized teeth for their diet of mostly leaves, along with the males possessing a larger hyoid bone located near the vocal chords, which enables their loud calls. The Guatemalan Black is a diurnal howler, which means it is active during the day and it sleeps at night, as well as being arboreal, meaning it dwells in the trees most of its life. They are a social species that lives in groups up to ten members strong, which helps in alerting, foraging, and general upkeep through grooming. Some groups can be as large as sixteen, while larger groups are plausible, however at these sizes it is unlikely to function as well as a smaller group. Their diets consist of mostly leaves, and fruits, however they will snack on a flower here and there and their favorite tree of all is the breadnut, which provides most food during some seasons. Not a particularly active species, the Guatemalan Black Howler would rather lounge about during the day; eating takes up a quarter of the day while moving locations for eating consists of only about a tenth of their daily activity. The rest of the day is devoted to socializing and grooming, with some other random antics. Females are old enough to have offspring by four years of age, while males may take up to eight years to reach maturity, and their total life-spans are an average of twenty years. The Guatemalan Black Howler’s binomial name (its species and genus) is Alouatta pigra, the Alouatta’s as a genus make up most of the Howler Monkeys, which are the largest of the New World Monkeys with but a few possible exceptions. Alouatta is home to all of the howler monkeys (ten species and ten subspecies), and belongs to the subfamily Alouattinae. Alouattinae belongs to the family Atelidae which is one of the four families of New World Monkeys; this includes the howler monkeys, along with spider monkeys, woolly monkeys, wooly spider monkeys, and Yellow-tailed Woolly Monkeys. Atelidae belongs to the Parvorder Platyrrhini, which contains all New World Monkeys, and includes Marmosets and Muriquis. Platyrrhini belongs to the infraorder Simiiformes, or ‘higher primates’, and this includes all New World and Old World monkeys from South America and Africa, and includes gibbons, great apes, and the family Hominidae of which we are members. Simiiformes belongs to the Suborder Haplorrhini, otherwise called dry-nosed primates; this includes all of the higher primates as well as Tarsiers. Haplorrhini belongs to the Order Primates, which is all related apes, monkeys, lorids, galagos, lemurs and human ancestors. Primates are in the class of Mammalia of the phylum Chordata in the Kingdom of Animalia. Fact The Guatemalan Black Howler is sympatric with another species, the Mantled Howler. Sympatric means that they share the same niche and territory, and encounter each other in the wild, they are also closely related. Warning The Guatemalan Black Howler is an Endangered Species, and is close to being classified as Critically Endangered if nothing is done to curb the loss of the species. In the next 30 years the IUCN expects to see a population loss of over 60%, making this species on the more endangered alive today. Major threats are habitat loss, poaching, and capture for use as ‘pets’. Full Article default
mon 3 Easy Steps to Save Money for Travel By everintransit.com Published On :: Thu, 30 May 2019 21:45:27 +0000 Finding ways to save money is much easier than you think, because you’re probably spending money you don’t have to spend. The article 3 Easy Steps to Save Money for Travel originated at EverInTransit.com Full Article Points + Miles Travel Tips credit card points food saving money
mon 12 Peruvian Festivals, One for Each Month of the Year! By feedproxy.google.com Published On :: Mon, 09 Mar 2015 20:53:32 +0000 Perhaps you've read somewhere or other that there are over 3,000 traditional Peruvian festivals held throughout the year? It's a popular claim that pops up time and again in guidebooks and on websites, and though we ourselves haven't verified the number, it certainly wouldn't surprise us! Peru is a country that holds onto its traditions while increasingly embracing innovation as well, a perfect storm for festivals and fiestas of all types to flourish and to grow. If you're planning to visit Peru, you might find yourself intrigued by the prospect of observing, or even participating in, one of these many different Peruvian festivals. If that's the case, you're in luck--we've taken the liberty to compile a list of some of our favorite Peruvian festivals, including one for each month of the year in hopes that you'll find something that corresponds with the dates of your trip. Keep in mind that this is very much just the tip of the iceberg--all of these Peruvian festivals are fantastic, but there are many more that we've had to leave out simply due to the nature of our list. If we haven't included any options that work out with your travel itinerary, don't fret--get to researching and we're sure you'll find the festival for you. So without further ado, let's get to it! Here is our list of twelve awesome Peruvian festivals, one for each month of the year: 1. January--Trujillo Marinera Festival Trujillo, a coastal city in northern Peru, is the traditional home of the marinera, an elegant couple's dance making use of handkerchiefs as props. Since 1986 it's been the official national capital of this dance, a status celebrated annually in a month-long marinera festival held throughout the city! The Festival de Marinera, as it's known in Spanish, features dance competitions, parades, and even exhibitions of the Peruvian Paso, a breed of horse also recognized as part of the cultural patrimony of the Trujillo region. One of our favorite Peruvian festivals, this one is a can't miss if you find yourself in the area during January. 2. February--Fiesta de la Candelaria The Fiesta de la Candelaria is not only the largest and most famous festival in Peru, but also one of the largest in South America as a whole--in fact, throughout the continent, it's only dwarfed by the world-famous Carnival in Rio de Janeiro and the Carnaval de Ouro in Bolivia. The first of many religious Peruvian festivals on our list, the Fiesta de la Candelaria celebrates the Virgin of Candelaria, the patron saint of the town of Puno where the festivities are held. Music and dance are at the core of this festival, all of it performed by elaborately-costumed participants numbering well over 40,000. An incredible two week-long synthesis of indigenous and Catholic traditions, this is one of the most iconic Peruvian festivals. 3. March--Festival Internacional de la Vendimia Depending upon where Easter falls during a given year, the month of March can either be very busy or very quiet as far as major Peruvian festivals are concerned. That said, we figured we may as well take a break from the religious festivals to focus on something else with a different sort of appeal--wine! The Ica Region of Peru is famous for a number of things, the Nazca Lines and the desert oasis of La Huacachina among them, but those in-the-know also recognize it as the finest wine-producing region in the country. This role has been celebrated annually in March since the 1950s during the Festival Internacional de la Vendimia, or the International Harvest Festival, in which a queen is famously chosen to ceremoniously stomp the first grapes of the season. 4. April--Festividad del Señor del los Temblores del Cusco Image appears courtesy of www.photoexperience.net. El Señor de los Temblores, or the Lord of the Earthquakes, is the patron saint of Cusco and the celebratory focus of this major Holy Week celebration. The story goes that during an earthquake here in 1650, a canvas image of Jesus Christ was held to the sky as prayers were offered, causing the tremors to subside and saving the town from ruin. Since then, this statue commemorating the original image has become the focal point of an important annual celebration. Each Easter Monday at 7 PM, the statue is removed from Cusco's cathedral and paraded throughout the city. Amazingly, it's said that the statue was not originally black, but rather that its color is due to years of exposure to smoke from incense during religious ceremonies. 5. May--Fiesta de las Cruces First of all, let's be clear: the Fiesta de las Cruces, or the Festival of the Crosses, is not a uniquely Peruvian celebration. However, the way the Peruvians celebrate it does make it one of the most important Peruvian festivals. You see, the Festival of the Crosses is not held in just one spot in the country. Rather, the festival is celebrated in towns and cities throughout Peru, each putting their own unique spin on things. Though the name may conjure up solemn images, don't worry--festivals throughout the Peruvian highlands include music, dancing, and even events such as bullfighting as part of the celebrations. 6. June--Inti Raymi Inti Raymi, the ancient Inca Festival of the Sun, is one of the most traditional Peruvian festivals on our list, indigenous in design and untouched by Catholic tradition. Held annually on June 24th, Inti Raymi is meant to celebrate the Winter Solstice--remember that we're in the Southern Hemisphere here! Banned by the Spanish and the Catholic Church after 1535, the modern incarnation of the celebration began in 1944 based on the few historical records of the festivities that managed to survive. Since then it has grown in size and scope, and though sometimes derided as tourist pageantry by detractors, its historical and cultural significance definitely make it worth checking out among the many Peruvian festivals. 7. July--Fiesta de la Virgen del Carmen Image appears courtesy of canadiansocietyforasianarts.org. Another fine example of traditional Andean culture blended with Catholicism, the Fiesta de la Virgen del Carmen is held annually around the 16th of July in the relatively small town of Paucartambo, some four hours outside of Cusco. This three or four day festival is nominally religious but also one of the biggest and wildest parties in Peru, drawing visitors from all over the country, many of whom pass the nights sleeping under the stars as there's simply not enough space in town! If you know what you're looking for, you'll actually notice some serious Peruvian history depicted in the festival's songs, costumes, and dance--for example, black-masked dancers represent African slaves imported to work the silver mines here during the colonial era. 8. August--Día de Santa Rosa de Lima Santa Rosa de Lima was the first native-born American saint canonized by the Catholic Church, and her legacy is celebrated throughout the world. However, it should come as no surprise that the grandest festivities take place in her home country of Peru. On August 30th, the anniversary of her death, celebrations and memorials take place throughout the country, the most famous being in Santa Rosa de Quives just outside of the capital city itself. 9. September--Mistura Culinary Festival As you should know by now, Peruvian cuisine is some of the world's best and Lima in particular features what is probably South America's most impressive culinary scene. And as if the food wasn't enticing enough year round, the prospect of eating your way through Peru becomes even more appealing each September when the Mistura Culinary Festival rolls around. Featuring over 200 restaurants and bars not to mention plenty of outdoor vendors and food carts, well over half a million visitors stop by to enjoy the festival's offerings over the course of some ten days in mid-September. Though certainly not one of the most traditional Peruvian festivals on our list, this is without a doubt the most delicious. 10. October--Procesión del Señor de los Milagros The story might sound a bit familiar--an 18th Century earthquake destroyed a good part of town leaving only this iconic image of Jesus Christ standing. This was considered a miracle, the image became even more venerated, and with time the celebration of its feast day became the largest religious celebration in Peru featuring one of the longest processions of any religious gathering in the world. If you're just looking to have fun, this one probably isn't for you--however, this considerably more solemn celebration is one of the most important Peruvian festivals and we couldn't leave it off our list. 11. November--Puno Week Perhaps the name Puno rings a bell? If so, you've got a good memory--this is the same city where our February festival choice of the Fiesta de la Candelaria took place! Puno Week takes place during the beginning of November and centers around November 5th, also known as Puno Day. The purpose of Puno Day, and by extension Puno Week, is to celebrate the legendary birth of one Manco Cápac, said to be the first Inca. This involves a very interesting reenactment of his arrival on the shores of Lake Titicaca bordering the city--and it's also just a great excuse to party the whole week long. 12. December--Santuranticuy Image appears courtesy of www.cuscoperu.com. As we wind down our list, a few things should by now be obvious: the first is that Peruvians love their festivals, and the second is that many of these Peruvian festivals feature religious--and here that means Catholic--themes. The final entry on our list is of course no exception--Santuranticuy is held exclusively in the city of Cusco each year on Christmas Eve, December 24th, and is essentially a massive outdoor marketplace set up to celebrate the holiday. The festival's name, which means "sale of saints," is quite appropriate, as the primary draw here are dolls, sculptures, and figurines used to decorate the nacimientos, or Catholic nativity scenes, found in many Peruvian homes during the Christmas season. However, even if you aren't religious, you're sure to find something of interest at this most shopper-friendly of Peruvian festivals. Full Article Food and Festivals Machu Picchu Inca Trail Places To See and Stay festivals Peru
mon The Majestic Monolith can become The Citadel By feedproxy.google.com Published On :: Wed, 08 Apr 2020 18:50:15 +0000 The vast majority of web applications should start life as a Majestic Monolith: A single codebase that does everything the application needs to do. This is in contrast to a constellation of services, whether micro or macro, that tries to carve up the application into little islands each doing a piece of the overall work.… keep reading Full Article Uncategorized
mon Fed Judge Releases 21-Yr-Old Man To “Clean and Sober House” After Appearing In Court For Sexually Assaulting 12-Yr-Old Girl For One Month While Hiding In Her Bedroom By 100percentfedup.com Published On :: Fri, 08 May 2020 18:49:10 +0000 The following article, Fed Judge Releases 21-Yr-Old Man To “Clean and Sober House” After Appearing In Court For Sexually Assaulting 12-Yr-Old Girl For One Month While Hiding In Her Bedroom, was first published on 100PercentFedUp.com. The normalizing of pedophilia is not a far-right conspiracy theory... Continue reading: Fed Judge Releases 21-Yr-Old Man To “Clean and Sober House” After Appearing In Court For Sexually Assaulting 12-Yr-Old Girl For One Month While Hiding In Her Bedroom ... Full Article Featured Left News
mon A neuroglobin-based high-affinity ligand trap reverses carbon monoxide-induced mitochondrial poisoning [Molecular Biophysics] By feedproxy.google.com Published On :: 2020-05-08T03:41:14-07:00 Carbon monoxide (CO) remains the most common cause of human poisoning. The consequences of CO poisoning include cardiac dysfunction, brain injury, and death. CO causes toxicity by binding to hemoglobin and by inhibiting mitochondrial cytochrome c oxidase (CcO), thereby decreasing oxygen delivery and inhibiting oxidative phosphorylation. We have recently developed a CO antidote based on human neuroglobin (Ngb-H64Q-CCC). This molecule enhances clearance of CO from red blood cells in vitro and in vivo. Herein, we tested whether Ngb-H64Q-CCC can also scavenge CO from CcO and attenuate CO-induced inhibition of mitochondrial respiration. Heart tissue from mice exposed to 3% CO exhibited a 42 ± 19% reduction in tissue respiration rate and a 33 ± 38% reduction in CcO activity compared with unexposed mice. Intravenous infusion of Ngb-H64Q-CCC restored respiration rates to that of control mice correlating with higher electron transport chain CcO activity in Ngb-H64Q-CCC–treated compared with PBS-treated, CO-poisoned mice. Further, using a Clark-type oxygen electrode, we measured isolated rat liver mitochondrial respiration in the presence and absence of saturating solutions of CO (160 μm) and nitric oxide (100 μm). Both CO and NO inhibited respiration, and treatment with Ngb-H64Q-CCC (100 and 50 μm, respectively) significantly reversed this inhibition. These results suggest that Ngb-H64Q-CCC mitigates CO toxicity by scavenging CO from carboxyhemoglobin, improving systemic oxygen delivery and reversing the inhibitory effects of CO on mitochondria. We conclude that Ngb-H64Q-CCC or other CO scavengers demonstrate potential as antidotes that reverse the clinical and molecular effects of CO poisoning. Full Article