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It’s Ravishing Form vs. Segera in the feature event




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Knotty Legend claims the General Rajendrasinhji Million




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Hyderabad Winter Races to commence on November 10




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India steps up critical mineral acquisition plans in Africa, challenging China’s dominance

Race for critical minerals primarily focuses on cobalt and copper – key EV battery making metals, apart from lithium.




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Foreign brokerages say BJP’s lower-than-expected victory to delay tough reforms but expect policy continuity

Foreign Brokerages predict fiscal consistency with a populist twist under Modi 3.0




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Two pre-Independence era acts to be re-enacted: Aircraft Act and Boilers Act get modern overhaul

In the upcoming Lok Sabha session, the Government will re-enact the Aircraft Act of 1934, introduce the Coffee Promotion Bill, and revamp the Indian Boilers Act of 1923 to modernise regulations and support the ‘Make in India’ initiative




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Govt issues operational guidelines for under PM-Surya Ghar: Muft Bijli Yojana

A total financial outlay of ₹800 crore has been allocated for this component, providing ₹1 crore per selected model solar village, the Ministry said




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India and Brazil to collaborate on SAF, leverage biofuel expertise to decarbonise aviation

The joint statement emphasised collaboration in technology exchange, joint research, and development initiatives to optimize SAF production processes and create frameworks encouraging investment in SAF production.




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Need clear laws, standard operating procedures to protect workers, manufacturers' interests: GTRI

Amid the ongoing Samsung workers’ strike in Tamil Nadu, economic think tank GTRI suggests seven-step strategy to foster a more stable industrial environment in the country




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FDI policy: Instead of overall review, govt may continue with tweaks

Focus will be on liberalising sector specific policy as and when required; improving processes




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Precooked, ready to eat food to attract 18% GST: Kerala AAR

Kerala Chicken Curry, Chettinadu Chicken Curry, Chicken Biryani, Mutton Curry, Mutton Roast, Beef Fry, Beef Roast etc. constitutes ‘ready to eat packaged food’ more specifically than ‘prepared or preserved meat: AAR




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Mid-tier exuberance: Range Rover Velar

Land Rover’s straightforward segmentation puts its mid-tier Velar in the spotlight




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2024 Porsche Panamera makes its Indian debut

The Panamera benefits from a new cabin, complete with a 12.6-inch instrument panel, a 10.9-inch touchscreen, and a passenger display




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Cybercrimes on rise: TN Police warns public; Chennai, Coimbatore, 2-tier cities vulnerable




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Trap cameras in Darjeeling to track movement of melanistic leopards




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ModaXL 200 mg Review - Dosage, Interactions, Side Effects (Full Guide)

Want to order ModaXL 200 mg in 2024? Read this guide and learn more about the smart drug ModaXL. Safety, correct dosages, possible side effects, best places to buy the nootropic and much more in this helpful review.




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Immunotherapy approach shows potential in some people with metastatic solid tumors

A new cellular immunotherapy approach shrank tumors in 3 of 7 patients with metastatic colon cancer, in a small NCI clinical trial. Normal white blood cells from each patient were genetically engineered to produce receptors that recognize and attack their specific cancer cells.




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Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer

An NCI trial shows that giving patients pembrolizumab after surgery for high-risk muscle invasive bladder cancer doubles the median length of time that they remain cancer free, compared with observation alone after surgery.




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Data | Malappuram, Palakkad and Wayanad lag behind other Kerala districts 

While inter-district disparities exist, they were not as stark in Kerala compared to Tamil Nadu




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Why ‘one nation, one election’ would strike a blow against federalism | Data

The idea of simultaneous elections is untenable if its impact on existing Assemblies and the three-tier system is considered.




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Uddhav Thackeray’s ‘offer’ to Nitin Gadkari draws jeers from BJP

Devendra Fadnavis says BJP leader’s name will be first when Maharashtra list candidates are announced



  • Lok Sabha Elections

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Nitish Kumar skipped NITI Aayog meet over refusal of special category status to Bihar: CPI(ML) Liberation leader

Mehboob Alam, CPI(ML) L leader in the Bihar Assembly, said, “I must say that Kumar skipped the meeting out of embarrassment over the refusal of the Centre to grant special category status to Bihar.”




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Wayanad landslide: More than 1,000 government employees engaged in 24x7 relief operations, says CMO

The government staff are handling the coordination of the search and rescue effort, distribution of relief materials, counselling of landslide victims with medical conditions




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‘Father of Indian chess boom’: The Anand effect that’s shaping a ‘golden generation’

The country swept both the men's and women's gold at the 45th Olympiad in Budapest, Hungary




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Injury is fine now, next big target is 2025 World Championship: Neeraj Chopra

Neeraj Chopra battled an adductor muscle niggle throughout the year and it also affected his performance at both the Olympics and the DL finale, where he also competed with a fractured left hand




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International hockey set to return to New Delhi after 10 years; veteran players Zafar Iqbal, Harbinder Singh hail Indian team

Mr. Iqbal, a gold medallist at the 1980 Moscow Olympics and captain of the 1982 Asian Games silver-winning Indian team, is hopeful for growth of Indian hockey after the bronze medals in the Tokyo and Paris Olympics.




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World junior shooting championship | Shardul Vihan and Sabeera Haris win mixed trap bronze

Parisha and Mukesh won the silver and bronze in the 50-metre free pistol event in the junior women’s and junior men’s sections respectively




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Magali Koenig : courir apres la pluie / direction editoriale, Geraldine Lay, Pierre Starobinski. [Accompagne de], Les yeux dans le samovar / Blaise Hofmann

[Arles] : Actes Sud, [2022]




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The journal of the Civil War era [electronic resource]

Chapel Hill, NC : University of North Carolina Press, 2011-




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A lateral flow strip for on-site detection of homocysteine based on a truncated aptamer

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00274A, Paper
Yunqing Wu, Tianyu Huang, Xin Chen, Mingyuan Wang, Xiaoli Wang, Yuting Zhang, Nandi Zhou
A lateral flow strip based on a truncated aptamer for on-site detection of homocysteine in human serum.
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Direct detection of dithiocarbamate fungicides by SALDI/MS using porous TiC ceramic powder as a substrate

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY01533E, Paper
Hiroshi Moriwaki, Issey Osaka, Kotaro Hashimoto, Osamu Yamada
Direct detection of dithiocarbamate fungicides (DTCs) has been achieved by SALDI/MS using porous titanium carbide (TiC) ceramic powder as a substrate.
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Near-infrared responsive gold nanorods for highly sensitive colorimetric and photothermal lateral flow immuno-detection of SARS-CoV-2

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00347K, Paper
Xiaohui Liu, Jingwen Li, Kun Wang, Xiang Li, Shenming Wang, Gengchen Guo, Qiaowen Zheng, Maosheng Zhang, Jingbin Zeng
We developed a colorimetric and photothermal dual-mode LFIA platform for sensitive and selective SARS-CoV-2 N protein detection based on gold nanorods.
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Discrimination of Diptera order insects based on their saturated cuticular hydrocarbon content using a new microextraction procedure and chromatographic analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00214H, Paper
Open Access
Lixy Olinda León-Morán, Marta Pastor-Belda, Pilar Viñas, Natalia Arroyo-Manzanares, María Dolores García, María Isabel Arnaldos, Natalia Campillo
The nature and proportions of hydrocarbons in the cuticle of insects is characteristic of the species and age. Chemical analysis of cuticular hydrocarbons allows species discrimination, which is of great...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Characterizing a visual lateral flow device for rapid SARS-CoV-2 virus protein detection: pre-clinical and system assessment

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02075D, Paper
Natpapas Wiriyachaiporn, Jetnapang Kongrueng, Kannika Sukkuea, Rattana Tanrattanawong, Jarunee Vanichtanankul, Thanaya Saeyang, Tararat Jantra, Deanpen Japrung, Weerakanya Maneeprakorn, Suwussa Bamrungsap, Pareena Janchompoo, Ekawat Pasomsub
Analytical and pre-clinical evaluation of a visual screening lateral flow device for SARS-CoV-2 virus protein detection and its system characterization.
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An immunochromatographic strip sensor for rapid and sensitive detection of candesartan, olmesartan medoxomil, and irbesartan in herbal beverages

Anal. Methods, 2024, 16,2359-2367
DOI: 10.1039/D4AY00151F, Paper
Dingyu Li, Aihong Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu, Xiaoling Wu
Sartans, as a class of antihypertensive drugs, pose a threat to human health when illegally added to herbal beverages.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Α simplified lateral flow immunosensor for the assay of carcinoembryonic antigen in low-resource settings

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00381K, Paper
Open Access
Ioanna Tsogka, Electra Mermiga, Varvara Pagkali, Christos Kokkinos, Anastasios Economou
Carcinoembryonic antigen (CEA) is a glycoprotein widely used as a tumor marker. In this work, a colorimetric lateral flow immunosensor is developed for rapid and low-cost quantification of CEA in...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Good, but not enough: On the extended coverage of the Ayushman Bharat scheme

Extension of free health coverage to all over 70 years is good, but more needs to be done  




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Politicising the laddu: On the Tirupati laddu and its ‘adulteration’

The Tirupati laddu issue should be limited to one of quality control




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Sweet and sour: On the laddu ‘adulteration’ case  

The inquiry into laddu adulteration must not be communalised




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A Korean win: On the 2024 Nobel Prize in Literature

A Nobel raises Korean prose to success levels of its drama and music 




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​Allow for deliberation: On the legitimate demands of Ladakh

The lack of a legislature and regional autonomy in Ladakh has led to the current protests




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'He Doesn't Have The Air He Is Raj Thackeray's Son'

'I love to meet people.'




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Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00660G, Review Article
Shutang Li, Jinfei Yang
As research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.
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Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamides

RSC Med. Chem., 2024, 15,3469-3476
DOI: 10.1039/D4MD00422A, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Hugo Kocek, Dominika Chalupská, Milan Dejmek, Alexandra Dvořáková, Michala Zgarbová, Michal Šála, Karel Chalupský, Petra Krafčíková, Tomáš Otava, Matúš Drexler, Eliška Procházková, Blanka Klepetářová, Milan Štefek, Ján Kozic, Helena Mertlíková-Kaiserová, Evzen Boura, Jan Weber, Radim Nencka
SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamides.
The content of this RSS Feed (c) The Royal Society of Chemistry




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SLL-1A-16 suppresses proliferation and induces autophagy in non-small-cell lung cancer cells via the AKT/mTOR signaling pathway

RSC Med. Chem., 2024, 15,3460-3468
DOI: 10.1039/D4MD00405A, Research Article
Xiaoqin Luo, Jin Wang, Ruichang Wang, Jiabing Lian, Mengnan Guo, Hongrui Zhou, Mengxue Zhang, Zhe Yang, Xiaolong Li, Xianran He, Xiuli Bi
Schematic of proposed mechanism for the treatment of the SLL-1A-16 inhibiting the proliferation in NSCLC.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Next-generation EGFR tyrosine kinase inhibitors to overcome C797S mutation in non-small cell lung cancer (2019–2024)

RSC Med. Chem., 2024, 15,3371-3394
DOI: 10.1039/D4MD00384E, Review Article
Debasis Das, Lingzhi Xie, Jian Hong
Prospects of novel fourth-generation EGFR-TKIs overcoming C797S-mediated resistance in non-small cell lung cancer.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00517A, Research Article
Open Access
Arianna Amenta, Susanna Comi, Marcelo Kravicz, Silvia Sesana, Antonia Antoniou, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca Re
A novel, glutathione-activated prodrug of pimasertib (PROPIMA) has been developed. PROPIMA showed ability to inhibit tumour cell migration and proliferation controlled over time, while also achieving a high incorporation rate into liposomes.
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Design, synthesis, and evaluation of benzhydrylpiperazine-based novel dual COX-2/5-LOX inhibitors with anti-inflammatory and anti-cancer activity

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00471J, Research Article
Poorvi Saraf, Bhagwati Bhardwaj, Akash Verma, Mohammad Aquib Siddiqui, Himanshu Verma, Pradeep Kumar, Samridhi Srivastava, Sairam Krishnamurthy, Saripella Srikrishna, Sushant Kumar Shrivastava
Screening piperazine derivatives via ChEMBL database led to the design and synthesis of novel dual COX-2/5-LOX inhibitors with strong anti-inflammatory, analgesic, and anti-cancer activity.
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Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00673A, Review Article
Juhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong Jun
Potential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.
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Continuous flow synthesis of N,N-dimethyltryptamine (DMT) analogues with therapeutic potential

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00562G, Research Article
Open Access
Andreas Simoens, Andreas Dejaegere, Marthe Vandevelde, Christian V. Stevens
Flow chemistry allows for the rapid and clean synthesis of therapeutically relevant tryptamines in good yields, including the large scale drug rizatriptan.
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