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Two in one: merging photoactivated chemotherapy and photodynamic therapy to fight cancer

By pubs.rsc.org
Published On ::

Chem. Sci., 2024, 15,17760-17780
DOI: 10.1039/D4SC04608K, Perspective
Open Access
Kirill M. Kuznetsov, Kevin Cariou, Gilles Gasser
Combining photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) into one single compound allows to achieve more efficient light-induced therapy.
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FragGen: towards 3D geometry reliable fragment-based molecular generation

By pubs.rsc.org
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Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC04620J, Edge Article
Open Access
Odin Zhang, Yufei Huang, Shichen Cheng, Mengyao Yu, Xujun Zhang, Haitao Lin, Yundian Zeng, Mingyang Wang, Zhenxing Wu, Huifeng Zhao, Zaixi Zhang, Chenqing Hua, Yu Kang, Sunliang Cui, Peichen Pan, Chang-Yu Hsieh, Tingjun Hou
FragGen introduces a novel fragment-based AI-based molecular design method. It proposes the geometry handling protocol to improve the generation quality and has been applied to design highly bioactive type II kinase inhibitors.
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Photo-triggered NO release of nitrosyl complexes bearing first-row transition metals and therapeutic applications

By pubs.rsc.org
Published On ::

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06820C, Review Article
Open Access
Seungwon Sun, Jisu Choe, Jaeheung Cho
In biological systems, nitric oxide (NO) is a crucial signaling molecule that regulates a wide range of physiological and pathological processes. Given the significance of NO, there has been considerable...
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Phenacylselenoesters allow facile selenium transfer and hydrogen selenide generation

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Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05788K, Edge Article
Open Access
Utsav Dey Sarkar, Mahima Rana, Harinath Chakrapani
A new series of phenacylselenoesters that generate hydrogen selenide in the presence of esterase and a biological thiol under ambient conditions is reported.
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Steering N/S coordination number to accelerate catecholase-like catalysis over low-coordinated Cu site

By pubs.rsc.org
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Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05014B, Edge Article
Open Access
Meng Yuan, Nannan Xia, Ziheng Huang, Chaofeng Huang, Xun Hu, Fei He
Modulating the coordination configuration of metal Cu center through steering the N/S coordination number around Cu center boosted the catalytic activity of catechol oxidase-mimicking nanozyme.
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A polymer deposition-mediated surface-charge reformation strategy: reversing the MOF biomineralization behavior

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Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05935B, Edge Article
Open Access
Yanbin Xu, Huangsheng Yang, Anlian Huang, Linjing Tong, Wei Huang, Guosheng Chen, Wei Yi, Siming Huang, Gangfeng Ouyang
A biocompatible polymer deposition-mediated surface-charge reformation strategy is reported that enables the in-place MOF biomineralization onto different enzyme templates.
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Large second harmonic generation and birefringence from extended octupolar π-conjugated structures

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Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05756B, Edge Article
Open Access
Danyang Dou, Bingbing Zhang, Daqing Yang, Ying Wang
By adopting an extended octupolar π-conjugation strategy, two excellent optical functional materials with a strong SHG response and large birefringence were prepared.
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Tailoring Hierarchical MnO2 Nanostructures on Self-Supporting Cathodes for High-Mass-Loading Zinc-Ion Batteries

By pubs.rsc.org
Published On ::

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06182A, Edge Article
Open Access
Weijie Zheng, Zhibiao Cui, Cong Liu, Libei Yuan, Shengsong Li, Lilin Lin, Tao Meng, Liangui Yang, Yexiang Tong, Dong Shu
Aqueous zinc-ion batteries (AZIBs) with MnO2 cathodes have promising application prospects, however, their performance is hindered by their low efficiency and insufficient life. By leveraging the nanomicellar properties of cetyltrimethylammonium...
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Simultaneous generation of hydroxyl and hydrogen radicals from H+/OH− pairs caused by water–solid contact electrification

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Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC06227B, Edge Article
Open Access
Fengjie Chen, Jingde Wu, Dou Wang, Yu Xia, Qingyuan Song, Ying Liang, Pu Wang, Bolei Chen, Yong Liang, Yongguang Yin, Yawei Wang, Maoyong Song, Guibin Jiang
Water–solid contact electrification is a common physical phenomenon involving interfacial electron and ion transfer, recently discovered to trigger unique redox reactions.
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Low temperature decoherence dynamics in molecular spin systems using the Lindblad master equation

By pubs.rsc.org
Published On ::

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05627B, Edge Article
Open Access
Timothy Krogmeier, Anthony W Schlimgen, Kade Head-Marsden
Understanding the spin dynamics in low-temperature settings is crucial to designing and optimizing molecular spin systems for use in emerging quantum technologies. At low temperatures, irreversible loss occurs due to...
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Differentiating carrier protein interactions in biosynthetic pathways using dapoxyl solvatochromism

By pubs.rsc.org
Published On ::

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05499G, Edge Article
Open Access
Matthew G. Miyada, Yuran Choi, Kyle Rich, James J. La Clair, Michael D. Burkart
A highly sensitive solvatochromic system was developed to monitor the loading and interactivity of carrier proteins associated with fatty acid, polyketide and non-ribosomal peptide biosynthesis.
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An interactive dual energy storage mechanism boosts high-performance aqueous zinc-ion batteries

By pubs.rsc.org
Published On ::

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05710D, Edge Article
Open Access
Shengen Gong, Meihua Zhu, Yan Zhou, Runan Li, Jianhua Zhang, Xiaoteng Jia, Danming Chao, Caiyun Wang
A conductive polymer cathode with high redox potential is realized by pre-doping Mn2+ into PANI, which demonstrates an interactive dual energy storage mechanism of reversible doping of multiple cations and dissolution–deposition of Mn2+.
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Photoactivated hydride therapy under hypoxia beyond ROS

By pubs.rsc.org
Published On ::

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06576J, Edge Article
Open Access
Xia Wang, Yijian Gao, Ting Wang, Zhaobin Wang, He Hang, Shengliang Li, Fude Feng
As compared to oxidative phototherapy, studies on reactive reductive species-participating photodynamic therapy (PDT) are rare. Porphyrins are typical photosensitizers restricted with oxygen level, but efficacy and selectivity are always uncompatible...
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Of cultural vulnerabilities

By www.thehindu.com
Published On :: Fri, 11 Nov 2016 00:00:00 +0530

A public adda withsix diverse voiceswill explore what happens when subculturesbecome part ofthe mainstream


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Leveraging equity taxation with arbitrage funds

By www.thehindubusinessline.com
Published On :: Sat, 05 Oct 2024 16:26:50 +0530

Arbitrage funds come with both – safety of capital as a debt fund and taxation of an equity fund.


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Centre to hold mega Digital Life Certificate camp for pensioners in Hyderabad

By www.newkerala.com
Published On :: Mon, 11 Nov 2024 12:44:02 +0530


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India warns 'least common denominator' model of UNSC reforms could derail major change

By www.newkerala.com
Published On :: Tue, 12 Nov 2024 16:18:01 +0530


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India warns 'least common denominator' model of UNSC reforms could derail major change

By www.newkerala.com
Published On :: Tue, 12 Nov 2024 16:20:01 +0530


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Centre releases funds for rural local bodies in Kerala, Meghalaya

By www.newkerala.com
Published On :: Tue, 12 Nov 2024 16:36:02 +0530


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Towards real-time myocardial infarction diagnosis: a convergence of machine learning and ion-exchange membrane technologies leveraging miRNA signatures

By pubs.rsc.org
Published On ::

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00640B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xiang Ren, Ruyu Zhou, George Ronan, S. Gulberk Ozcebe, Jiaying Ji, Satyajyoti Senapati, Keith L. March, Eileen Handberg, David Anderson, Carl J. Pepine, Hsueh-Chia Chang, Fang Liu, Pinar Zorlutuna
Rapid diagnosis of acute myocardial infarction (AMI) is crucial for optimal patient management.
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A gravity-driven tissue chip to study the efficacy and toxicity of cancer therapeutics

By pubs.rsc.org
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Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00404C, Paper
Open Access
Pouria Rafsanjani Nejad, Astha Lamichhane, Prasiddha Guragain, Gary Luker, Hossein Tavana
A 96-well plate format, fully-automated multi-organ tissue chip array with gravity-driven flow for cancer research.
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Multiple factors remain a hurdle in setting up centralised sewer networks, Kerala govt. informs NGT

By www.thehindu.com
Published On :: Tue, 05 Nov 2024 00:57:20 +0530

Faecal sludge treatment plants proposed in a radius of 15 km on cluster basis in urban and rural local bodies


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Kerala State school sports meet off to a vibrant start with grand inaugural ceremony

By www.thehindu.com
Published On :: Tue, 05 Nov 2024 01:10:23 +0530

The inaugural ceremony featured a march past with student athletes from 14 districts and the United Arab Emirates (UAE) parading from Durbar Hall Ground to the college ground


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A combat sport continues to attract Kerala’s youngsters

By www.thehindu.com
Published On :: Tue, 05 Nov 2024 18:15:55 +0530

Nivediya L. Nair, a defending champion in the fencing Épée category, was drawn to the sport as an eight-year-old a decade ago. Nakshathra A.R. was captivated by the valiant display of sword play by C.A. Bhavani Devi, the first Indian fencer to qualify for an Olympics, at Tokyo Olympics held in 2021.


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KITE gives technological edge to coverage of State school sports meet

By www.thehindu.com
Published On :: Tue, 05 Nov 2024 18:17:19 +0530


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ERCMPU set to become fully solar-powered dairy cooperative

By www.thehindu.com
Published On :: Tue, 05 Nov 2024 21:40:39 +0530


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RTO to probe operator’s failure to provide accommodation to students

By www.thehindu.com
Published On :: Wed, 06 Nov 2024 01:48:10 +0530


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Kerala HC adjourns hearing on plea against land acquisition for Wayanad township

By www.thehindu.com
Published On :: Wed, 06 Nov 2024 20:09:32 +0530


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Kerala High Court quashes criminal case against filmmaker Sreekumar Menon

By www.thehindu.com
Published On :: Wed, 06 Nov 2024 20:17:59 +0530


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Kerala School Sports & Games 2024: Athletics events to start on Thursday

By www.thehindu.com
Published On :: Wed, 06 Nov 2024 20:36:14 +0530


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Allow only dolly workers with police verification certificate to carry pilgrims to Sabarimala: Kerala HC

By www.thehindu.com
Published On :: Thu, 07 Nov 2024 11:44:35 +0530


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Hema Committee report: Preliminary inquiry in cases to be completed by December-end, Kerala govt tells HC

By www.thehindu.com
Published On :: Thu, 07 Nov 2024 14:44:04 +0530

Submission made in a progress report filed by Kerala govt in response to public interest litigation in High Court filed in connection with Hema Committee report


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Kerala State Sports & Games 2024: curiosity pulls in more people to baseball games

By www.thehindu.com
Published On :: Thu, 07 Nov 2024 19:18:02 +0530

Though not a very popular game like cricket, more youngsters are getting drawn into the sport, says a baseball coach


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Media rights cannot be restricted: Kerala High Court

By www.thehindu.com
Published On :: Thu, 07 Nov 2024 20:01:14 +0530

Expression by the media of any definitive opinion regarding the guilt or innocence of a party in an ongoing criminal investigation will not get protection under Article 19(1)(a), observes an HC bench


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Two more held in alleged cooperative society fraud

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 02:00:36 +0530


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Boxing competition disrupted by man claiming to be YouTuber in Kerala

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 10:08:15 +0530


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Kerala man arrested with nitrazepam tablets

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 10:09:01 +0530


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Contempt case hearing against Kerala govt. adjourned in directive to take over Jacobite churches

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 19:24:58 +0530


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Kerala, Tamil Nadu united to ensure that India belongs to everyone, says Kanimozhi

By www.thehindu.com
Published On :: Fri, 08 Nov 2024 21:24:15 +0530

DMK MP Kanimozhi was addressing an event held at the Ernakulam Town Hall to felicitate Sr. Vinitha, director of St. Teresa’s College, for her contributions to higher education, social welfare, and culture.


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State affected due to lack of support from Centre during disasters: Kerala CM

By www.thehindu.com
Published On :: Sat, 09 Nov 2024 19:38:50 +0530

Union government’s attitude reflects a desire for Kerala to suffer, says Pinarayi Vijayan


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Perumbavoor Urban Cooperative Society to witness novel election as aggrieved investors set to field panel to seize control

By www.thehindu.com
Published On :: Sat, 09 Nov 2024 19:58:11 +0530

Election for 11-member board set for November 24 after cooperative faces financial crisis due to alleged fraud in loan valuations and sanctions


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Seaplanes have potential to woo high-budget tourists to Kerala: Biju Prabhakar

By www.thehindu.com
Published On :: Sat, 09 Nov 2024 20:31:50 +0530

Aviation Secretary says these amphibious aircraft can link tourism locales in the State. A seaplane will operate a trial service from Kochi International Marina to the Mattupetty dam in Munnar on Monday


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1,000 consumer clubs to be formed on campuses, says Kerala Minister

By www.thehindu.com
Published On :: Mon, 11 Nov 2024 19:09:16 +0530


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Kerala School Sports & Games: Dispute over best school winners takes sheen off State school meet

By www.thehindu.com
Published On :: Mon, 11 Nov 2024 21:12:33 +0530

Students and teachers from two schools stage a protest over the result in the best school (athletics) category leading to police intervention during the valedictory function of Kerala School Sports & Games.


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Kerala School Sports & Games: Govt. determined to reclaim Kerala’s lost glory in sports, says CM Pinarayi Vijayan

By www.thehindu.com
Published On :: Tue, 12 Nov 2024 00:02:30 +0530

‘Kerala could attract investments worth ₹5,050 crore to the sports sector by becoming the first State to hold a sports summit’


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Government formulates ‘work from Kerala’ concept

By www.thehindu.com
Published On :: Tue, 12 Nov 2024 17:59:05 +0530

The idea is to leverage Kerala’s unique advantages from sustainable transport facilities, clean air and water besides open-minded people.


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Kerala HC quashes criminal case against former postal officials for taking possession of Waqf property

By www.thehindu.com
Published On :: Tue, 12 Nov 2024 18:29:32 +0530

The post office was functioning from 1999, even before the insertion of section 52A in Waqf Act, which makes purchase or possession of Waqf property without Waqf Board nod punishable


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Political soap opera

By www.thehindubusinessline.com
Published On :: Wed, 10 Jul 2013 15:52:17 +0530


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'Spirit'ual Kerala

By www.thehindubusinessline.com
Published On :: Sun, 08 Sep 2013 16:13:38 +0530


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  • R K Nair