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Thalamic Massa Intermedia in Children with and without Midline Brain Malformations [PEDIATRICS]

BACKGROUND AND PURPOSE:

The massa intermedia is a normal midline transventricular thalamic connection. Massa intermedia aberrations are common in schizophrenia, Chiari II malformation, X-linked hydrocephalus, Cornelia de Lange syndrome, and diencephalic-mesencephalic junction dysplasia, among others. We have noticed that massa intermedia abnormalities often accompany other midline malformations. The massa intermedia has never been formally evaluated in a group of exclusively pediatric patients, to our knowledge. We sought to compare and contrast the prevalence, size, and location of the massa intermedia in pediatric patients with and without congenital midline brain abnormalities.

MATERIALS AND METHODS:

Successive 3T brain MR imaging examinations from pediatric patients with and without midline malformations were procured from the imaging data base at a pediatric hospital. Massa intermedia presence, size, morphology, and position were determined using 3D-TIWI with 1-mm isotropic resolution. The brain commissures, septum pellucidum, hypothalamus, hippocampus, vermis, and brain stem were evaluated to determine whether alterations were related to or predictive of massa intermedia abnormalities.

RESULTS:

The massa intermedia was more frequently absent, dysmorphic, and/or displaced in patients with additional midline abnormalities than in those without. The massa intermedia was absent in 40% of patients with midline malformations versus 12% of patients with normal findings (P < .001). Massa intermedia absence, surface area, and morphology were predictable by various attributes and alterations of the commissures, hippocampus, hypothalamus, vermis, brain stem, and third ventricle.

CONCLUSIONS:

Most pediatric patients have a thalamic massa intermedia centered in the anterior/superior third ventricle. Massa intermedia abnormalities are commonly associated with other midline malformations. Normal-variant massa intermedia absence is a diagnosis of exclusion.




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Bigstar Media




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Saturn Remedies: शनि के इन उपायों को करने से दूर होगा शनि दोष

शनि कर्म के देवता हैं और आपके किए गए कार्य का फल जरूर देते हैं। शनिदेव को मनाने के लिए किए जाने वाले सनातनी उपाय को करके आप कुंडली के उन दोषों को दूर कर सकते हैं जिनके कारण आपको कष्ट उठाने पड़ते हैं।




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Psychological Horror Game The Medium Announced for Xbox Series X and PC

Bloober Team has announced psychological horror game, The Medium, for Xbox Series X and Windows PC via Steam. It will launch this holiday season and be available on Xbox Game Pass.

"Every one of our games has a central theme that drives its creative and technological design," said Bloober Team CEO Piotr Babieno.

"In The Medium, we focus on perspective and perception. When you change your point of view, you discover that things are more complicated and nuanced than you initially thought. The Medium is our most ambitious game ever and we can’t wait to show you how we’re translating this vision into a psychological horror."

View the reveal trailer below:

Here is an overview of the game:

Become a medium living in two different worlds: the real one and the spirit one. Haunted by the vision of a child’s murder, you travel to an abandoned hotel resort, which many years ago became the stage of an unthinkable tragedy. There you begin your search for difficult answers.

As a medium with access to both worlds, you have a wider perspective and can see more clearly that there’s no one simple truth to what others perceive. Nothing is what it seems, everything has another side.

The Medium features a “dual” soundtrack by Bloober Team’s Arkadiusz Reikowski and legendary composer Akira Yamaoka of Silent Hill fame.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443420/psychological-horror-game-the-medium-announced-for-xbox-series-x-and-pc/




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Vampire: The Masquerade - Bloodlines 2 Confirmed for Xbox Series X

It was confirmed at the Inside Xbox event today Vampire: The Masquerade - Bloodlines 2 will be getting a next generation release on the Xbox Series X. It was already confirmed the game will release on the PlayStation 4, Xbox One and Windows PC.

View the latest trailer below:

Here is an overview of the game:

Enter the World of Darkness and rise through vampire society. Experience Seattle - a city full of alluring, dangerous, characters and factions. You are dead now but stronger, quicker, more alluring and with potential for so much more. Choose to be brutal and unflinching or cultured and seductive. Use charm, cunning, terror and sheer will to rise through vampire society. What monster will you be?

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443424/vampire-the-masquerade-bloodlines-2-confirmed-for-xbox-series-x/




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Video game Ancestors lets you meddle with the epic story of evolution

Ancestors is the latest attempt to gamify millions of years of evolution but doesn't have the excitement gene, says Jacob Aron




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Peer into a giant, half-formed ship that can hold 18,000 containers

This image of an enormous ship under construction features in a new book and show that challenge common ideas about beauty - while the real ship may help cut carbon emissions




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There probably isn’t as much fake news in the media as we think

An analysis of the media consumption habits of people in the US shows that fake news makes up a tiny fraction of what they watch or read every day




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Animal Crossing Is the Breath of the Wild Postgame I Always Dreamed Of

Strange as it may sound, Animal Crossing: New Horizons feels like where Breath of the Wild should have ended up gameplay-wise.




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Jupiter is wetter than we thought, which helps explain how it formed

NASA's Juno spacecraft has found that Jupiter contains more water than measured by its predecessor, Galileo, solving a long-running planetary mystery




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Mars may have formed 15 million years later than we thought

Young Mars may have endured a series of huge collisions that smashed its mantle, throwing off our measurements of when it formed by up to 15 million years




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A planet could have been stolen from the solar system as it formed

Stars like our sun formed in a dense cluster with thousands of others, during which time they may have swapped planets




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Neutrinos determined where galaxies formed in the early universe

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Oxygen in lunar rocks suggests the moon formed in huge collision

A leading theory for the formation of the moon is that a planet called Theia smashed into the early Earth, but doubts remain. Now a new analysis of lunar rock supports this idea




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Pluto formed quickly with a deep ocean covering its entire surface

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Some black holes are way bigger than we can explain, and they may have come from supermassive stars that formed by devouring the other stars around them




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Rockets armed with talcum powder could stop deadly space junk

Thousands of dead satellites and chunks of debris in orbit are a threat to active satellites, but rockets that launch clouds of talcum powder may prevent a disastrous collision




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The moon is emitting carbon, raising questions about how it was formed

The leading hypothesis for how the moon formed involves a collision between a Mars-sized object and Earth that would have boiled away elements like carbon, making its discovery on the moon a mystery




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Those Who Framed Flynn Must Be Held Accountable

After more than three long years, the Justice Department has finally lived up to its name by dropping charges against my former boss, former National Security Adviser and retired Army Lt. Gen. Michael Flynn. He should have never been prosecuted.




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A Welcomed 1st Step Toward Justice for Ahmaud Arbery

I was not surprised either that it took two-plus months for arrests to come of two men and murder charges in the case. This only after the GBI was rightly called in.




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Zipline Deploys Medical Delivery Drones with U.S. Military

A military exercise in Australia demonstrates how small drones can airdrop critical medical supplies to soldiers in combat




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Drones: For When Medical Intervention Has to Get There Before an Ambulance Can

New York City study shows that drones could deliver life-saving medical supplies several minutes before an ambulance arrives




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In the 17th Century, Leibniz Dreamed of a Machine That Could Calculate Ideas

The machine would use an “alphabet of human thoughts” and rules to combine them



  • robotics
  • robotics/artificial-intelligence

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For Centuries, People Dreamed of a Machine That Could Produce Language. Then OpenAI Made One

OpenAI’s GPT-2 program churns out natural language that’s remarkably coherent—and that’s a problem



  • robotics
  • robotics/artificial-intelligence

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Map: Confirmed coronavirus cases, worldwide

More than 3.9 million people have been sickened and more than 270,000 killed by the coronavirus around the world. This map is updated daily.





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Ocarina Of Time's 'Saria's Song' Performed On 24 Partially Empty Wine Bottles

This is a video of musician and Instagrammer nathanleighsays performing Saria's Song (the Lost Woods theme) from The Legend Of Zelda: Ocarina Of Time on 24 partially empty wine bottles. How about that! Of course this would never work at my aunt's house on account of the bottles all playing the same note because they're empty. And the cats! Soooooo many cats. Keep going for the performance as well as a clip of Link learning Saria's song from the actual game.




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The Medium Release confirmed for Xbox Series X and PC with Silent Hill vibes



The makers of Blair Witch, Observer and Layers of Fear today announced a new psychological horror game - The Medium.




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DIRT 5 release date confirmed for PS5, Xbox Series X and existing consoles



Codemasters next racing game, DIRT 5 has been announced.




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Chorus: Rise as One release confirmed for PS5, Xbox Series X, PS4, Xbox



Chorus: Rise as One is a new space-combat shooter, revealed during Inside Xbox. Here's everything you need to know.




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FIFA 20 TOTS La Liga Confirmed with New Team of the Season Ultimate Team Cards



FIFA 20 Team of the Season So Far Premier League Squad is now live and features Lionel Messi, Luis Suarez and Antoine Griezmann.




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RPGCast – Episode 510: “The Anna Marie Seal Of Mediocrity”

We hope you’re not sick of Fire Emblem: Three Houses from last week, because we’ve got even more this episode. We discuss strategies for raising professor rank and recruiting, in case you need some tips. We also cover a variety of games and their official release dates. Finally, our briefs are more like long underwear this week.




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Ray of hope as Scots armed forces veterans wait two years for a mental health plan

ARMED forces veterans are facing a threat from an enemy they cannot see.




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Blueprint to protect the mental health of frontline medical workers

Researchers have developed a set of recommendations to manage the mental health of frontline medical workers during viral outbreaks, such as COVID-19.




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Tiny devices promise new horizon for security screening and medical imaging

Miniature devices that could be developed into safe, high-resolution imaging technology, with uses such as helping doctors identify potentially deadly cancers and treat them early, have been created.




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Coronavirus forces Russia to hold slimmed down Victory Day in blow to Putin




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The Half of It review – charming Netflix teen comedy takes on Cyrano

A talented trio of young actors enliven a familiar yet engaging tale of a queer love triangle at high school

There’s a satisfying ease to Netflix high school comedy The Half of It, a charming twist on the Cyrano de Bergerac formula that deserves slightly more attention than most of the streamer’s other made-to-order sleepover pics. A teen market that had been underserved by studios has now been exhaustively cornered by the company but often without much care or inventiveness, a conveyor belt of content that prioritises quantity over quality. It’s refreshing then to see a film such as this emerge from the same production line, slickly ticking all the same boxes but with a noticeable uplift in enthusiasm, grafting its own identity on to the boilerplate format.

Related: Never Have I Ever review – Netflix teen series slowly finds its voice

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U of M swimmer Wog named Canada West Female Athlete of the Year

Complacency is not a word in Kelsey Wog’s vocabulary. Every season, the fourth-year Bisons swimmer finds a way to take her game to the next level and break records along the ...




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Coronavirus Lockdown 3.0: Suspension of labour laws by fiat can only be an immediate-term response to the current crisis

There has been talk for some time now about easing labour laws, already seen in industry circles as being too rigid and acting as a drag on growth, specifically to facilitate emerging from the lockdown. And it’s not just a question of emerging from it, there’s also the issue of surviving what looks like being a brutal and prolonged global economic downturn. It was reported on Friday that ordinances were being issued in some states.





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End-of-life medical decisions being rushed through due to coronavirus

The covid-19 pandemic has led to rushed guidelines for doctors making treatment decisions, and has encouraged more people to make advance decisions on CPR and ventilation




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Russia's Putin urges unity as he presides over slimmed down Victory Day

President Vladimir Putin told Russians on Saturday they are invincible when they stand together as he presided over celebrations of victory in World War Two that were slimmed down because of the coronavirus outbreak.




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Junior India squad for Davis Cup, Fed Cup named

… Junior Asia/ Oceania Davis Cup and Fed Cup final qualifying event. The … players selected for the Junior Davis Cup include Dev V. Javia, Sandeep … Gogoi (reserve). The Junior Fed Cup team includes Anisha Kashyap, Bhakti … Junior Asia/ Oceania Junior Davis Cup will begin in Kuching, Malaysia ….




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Jessica Simpson feels 'body shamed' for 'having boobs'

The 39-year-old star has fired back at Vogue editor Sally Singer after a piece reflecting on the 2007 Met Gala which criticised her low cut






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Biden calls for immediate $13 minimum wage increase for frontline workers

The apparent Democratic nominee called for an immediate $13 minimum wage increase for essential workers and criticized President Trump for viewing these front-liners as “disposable."




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Michigan governor wants to ban guns from Capitol after armed anti-lockdown protests

In an interview, the governor, a possible Biden running mate, said she feels "intense pressure" to reopen the state.




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'Murder hornets' in Washington state threaten bees and whip up media swarm

Asian giant hornet, which became more active in the state in April, is the world’s largest and can kill humans with multiple stings

Researchers and citizens in Washington state are on a careful hunt for invasive “murder hornets”, after the insect made its first appearance in the US.

The Asian giant hornet is the world’s largest and can kill humans. But it is most dangerous for the European honeybee, which is defenseless in the face of the hornet’s spiky mandibles, long stinger and potent venom.

Continue reading...




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Critics alarmed by US nuclear agency's bid to relax rules on radioactive waste

Nuclear Regulatory Commission keen to allow material to be disposed of by ‘land burial’ – with potentially damaging effects

The federal agency providing oversight of the commercial nuclear sector is attempting to push through a rule change critics say could allow dangerous amounts of radioactive material to be disposed of in places like municipal landfills, with potentially serious consequences to human health and the environment.

Related: Coca-Cola and Pepsi falling short on pledges over plastic – report

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What an 1836 Typhus Outbreak Taught the Medical World About Epidemics

An American doctor operating out of Philadelphia made clinical observations that where patients lived, not how they lived, was at the root of the problem