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LifeSignals Receives CE Mark for ECG Remote Monitoring Patch

LifeSignals, based in Fremont, California, announced that it received the CE Mark for its LifeSignals ECG Remote Monitoring Patch. The patch, integrated with a remote monitoring platform, is designed as a continuous electrocardiography (ECG) and heart rate monitor. The ECG Remote Monitoring Patch is disposable and captures data for up to three days. The device […]




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Encouraging Signals for New Cancer Cell Therapy Strategies

Chimeric antigen receptor T-cell therapies have shown remarkable efficacy in leukemia and lymphoma patients who relapsed or were refractory to several prior treatments, but many challenges remain in the cancer cell therapy field. Strategies that may improve upon first-generation therapies were presented during the American Association for Cancer Research virtual meeting with encouraging early activity, […]




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Statement from Justice Department Spokesman Regarding President Obama’s Speech on U.S. Signals Intelligence

The U.S. Justice Department released the following statement by department spokesman Brian Fallon in response to President Obama’s speech on U.S. signals intelligence.



  • OPA Press Releases

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Relmada Therapeutics (RLMD): Sending The Right Signals?

Shares of Relmada Therapeutics Inc. (RLMD) have gained 19 percent so far this year and trade around $37.




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Blocking thrombospondin-1 signaling via CD47 mitigates renal interstitial fibrosis




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Signal Transduction and Targeted Therapy




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MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3β/β-catenin signaling




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Evolution and function of interleukin-4 receptor signaling in adaptive immunity and neutrophils




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Opioid and Hedgehog signalling pathways converge to modulate OA




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IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




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Sweet signals — gut–brain circuit for sugar identified




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ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling




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Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity




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Pandemic politics: Does the coronavirus pandemic signal China’s ascendency to global leadership?

The absence of global leadership and cooperation has hampered the global response to the coronavirus pandemic. This stands in stark contrast to the leadership and cooperation that mitigated the financial crisis of 2008 and that contained the Ebola outbreak of 2014. At a time when the United States has abandoned its leadership role, China is…

       




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Pandemic politics: Does the coronavirus pandemic signal China’s ascendency to global leadership?

The absence of global leadership and cooperation has hampered the global response to the coronavirus pandemic. This stands in stark contrast to the leadership and cooperation that mitigated the financial crisis of 2008 and that contained the Ebola outbreak of 2014. At a time when the United States has abandoned its leadership role, China is…

       




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The hit on the Taliban leader sent a signal to Pakistan


The death of Afghan Taliban leader Mullah Mansour in an American drone strike is a significant but not fatal blow to both the Taliban and their Pakistani Army patrons.

The critical question Afghans and Pakistanis are asking is whether this is a one-off or the beginning of a more aggressive American approach to fighting the war in Afghanistan.

Mullah Mansour became the Taliban's leader last year after it was revealed his predecessor, Mullah Omar, the founder of the Taliban, had been dead for two years from unknown causes.

Mullah Omar's death in a Pakistani hospital in Karachi had been covered up for two years by the Pakistani Army's intelligence service, the Inter Services Intelligence Directorate or ISI, and the cover-up allowed the ISI to manipulate the Taliban very effectively behind the scene. Mullah Mansour was the ISI's handpicked successor.

There was resistance to his selection by some Taliban commanders, but the ISI forced them to acquiesce.

Since the fall of Kabul to American and allied forces after 9/11, the Taliban leadership has made its headquarters in Quetta, the capital of Baluchistan province in Pakistan.

For 15 years the Quetta Shura, as the assembly of leaders is known, has been protected by the ISI in its Pakistani safe haven where it is free to plan operations, conduct training, raise money and prepare terrorist attacks to strike American, NATO and Afghan targets in Kabul and elsewhere. While drones pummeled Al Qaeda targets elsewhere in Pakistan, the Taliban leaders were immune.

So this operation is unprecedented, the first ever effort to decapitate the Afghan Taliban. Mullah Mansour apparently was killed in Baluchistan very close to the Afghan border. He pressed his luck too far it appears. It's too soon to know the details of how he was found, but he was likely visiting front-line commanders.

The ISI will find a successor. They will work with the powerful Haqqani network, inside the Taliban, which has its own sanctuary in Peshawar Pakistan. The challenge will be to hold together the fractious movement, especially as the so-called Islamic State (ISIS) is trying to rally dissidents to its cause and create an Islamic State Vilayet, or province, in Afghanistan. The ISI and the Haqqanis are prepared to be ruthless to keep control of the Taliban.

The elected Pakistani government led by Prime Minister Nawaz Sharif has been trying to persuade Mullah Mansour and the Quetta Shura to join in peace talks with the Afghan government, which is led by President Ashraf Ghani. The US and China have encouraged the political process. But Sharif has no power over the Pakistani military and its ISI minions.

Indeed, now that Prime Minister Sharif is engulfed in a scandal caused by the Panama papers, his goal is simply to survive in office, and some Pakistani political commentators expect the army to oust Nawaz Sharif in a soft coup this summer. The Afghan peace talks are not likely to get going as long as the army calls the shots in Pakistan.

The killing of Mansour in an unprecedented operation has produced elation in the Afghan security forces, who hope it does it actually does mark the start of more aggressive attacks against the safe havens in Pakistan. But that's probably a misplaced hope. A discreet operation in the border region is not the equivalent of hitting targets deeper inside Pakistani territory.

Inevitably, the attack will be another blow to U.S.-Pakistan relations, even if both Washington and Islamabad try to paper it over. The U.S. Congress, after years of passively accepting Pakistani duplicity, has become much less willing to fund arms deals and aid to the Pakistani army. A recent administration proposal to sell F16 jets to the Pakistani military at sweetheart prices has been killed, wisely, on The Hill.

The next U.S. president will confront a complex and worrisome challenge in Afghanistan and Pakistan. It is not quite as bad as the disaster President Barack Obama inherited eight years ago, but it is one of the toughest foreign policy issues the next team will face. What do the candidates think they can do about it? It's not too early to start pressing them for answers.

This piece was originally published by The Daily Beast.

Authors

Publication: The Daily Beast
Image Source: © Fayaz Aziz / Reuters
      
 
 




signal

Pandemic politics: Does the coronavirus pandemic signal China’s ascendency to global leadership?

The absence of global leadership and cooperation has hampered the global response to the coronavirus pandemic. This stands in stark contrast to the leadership and cooperation that mitigated the financial crisis of 2008 and that contained the Ebola outbreak of 2014. At a time when the United States has abandoned its leadership role, China is…

       




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Steven M. Johnson on Turn Signal Clothing

The inventor and humorist also was prescient about buses.




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19 signals dogs use to tell us what they want

Researchers have identified many of the gestures that dogs use to get humans to do their bidding.




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Almost half of American drivers don’t bother using their turn signals

And then they yell at cyclists for not following the rules.




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Shanghai Disneyland tickets sellout for opening day, signaling pent up demand for theme parks

It seems Chinese consumers aren't afraid to return to theme parks. Tickets for Monday's reopening of Shanghai Disney sold out within minutes.




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Sanctions send soft signals to Russia: Pro

Stephen Yates, CEO at DC International Advisory, says the sanctions that have slapped on Russia have not been hard-hitting at all.




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What Dow theory is signaling...

The economy is not that strong, says Jeffrey Hirsch, Stock Trader's Almanac, discussing market volatility and tracking movements in the Dow transports for signs of bear activity.




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Crude gets crushed after Saudis signal faster comeback from attacks

The crude crush continues after yesterday's surge. With CNBC's Seema Mody and the Futures Now traders, Brian Stutland from the CME and Anthony Grisanti at the NYMEX.




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April job losses may top 20 million, weekly jobless claims report signals

The number of continuing jobless claims rose to a greater-than-expected 22.6 million last week, signaling April job losses over 20 million.





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Weird radio signals spotted in our galaxy could solve a space mystery

Weird blasts of radio waves from space called fast radio bursts have been baffling astronomers since they were discovered, but after finding one in our galaxy we may finally know what creates them




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Ashwini Bidre murder: Cops record strong metal signals emanating from spots


The Navi Mumbai police restarted the search operation with experts' help early this month. Pic/Hanif Patel

The search for murdered policewoman Ashwini Bidre's mortal remains has reached the final stage. Of the nine locations that came up during the search, two, showing strong signals of presence of a metal object, have been zeroed on.

Having a radius of five metres, both locations are covered with mud that's nearly two metres deep. The police will now take a call on how to remove the objects from these locations, as they will need specialised machinery for it. After an initial investigation, the police had procured a gradiometer, an equipment to locate metal objects underwater, from Israel. "During the two-day search operation, experts found nine spots with the help of the equipment; strong signals emanated at two of the spots," said an officer.

These two locations are expected to have objects at a depth of 25 to 40 metres below the water surface. "The depth varies according to tide. Our search also revealed that the objects are covered with one-metre thick mud, which is hard and can't be removed manually," said the officer. These spots also have deep wells, said a source, adding, "Sending divers in these wells can be dangerous to their lives. Hence, we are considering bringing in machines capable of drilling deep underwater."

Bidre's husband Raju Gore told mid-day, "We are looking forward to the next step from the police, which involves removing the objects and lifting them to the surface."





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Fiesta Resort Saipan to rebrand as Crowne Plaza® Resort Saipan in 2022, signalling IHG's rapid expansion in Micronesia

IHG has signed a long-term agreement with Asia Pacific Hotels Inc to take on management of Fiesta Resort & Spa Saipan, in the Commonwealth of Northern Mariana Islands, from May 20201.The impressive 416-room hotel will rebrand as Crowne Plaza® Resort Saipan in 2022 following a refurbishment, before adding a 116-room extension by 2025. Alongside IHG's October announcement that it has taken on management of the 318-room Fiesta Resort Guam, a hotel that will rebrand as a Crowne Plaza in 2021, the combined 850 room count makes the biggest ever conversion signing for IHG's Australasia, Japan and Pacific Islands region.Saipan is the largest island of the Northern Mariana Islands and is part of the Commonwealth of the United States. A 20-minute flight from Guam, Saipan is characterised by sandy shores and mountainous landscapes, and boasts several championship golf courses. It has a borderline tropical rainforest climate and, with an average year-round maximum temperature of 28.9°C, Saipan ha...




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OECD study signals the importance of collective efforts by international organisations to improve global standard setting

The role of international organisations (IOs) is critical in the development of rules and standards that can help advance the well-being of citizens in an increasingly globalised world.




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United Kingdom Imports Intra Eu - Railway & Tram Tracks, Signals, Fixings, Etc.

Imports Intra Eu - Railway & Tram Tracks, Signals, Fixings, Etc. in the United Kingdom increased to 65.45 GBP Million in February from 52.78 GBP Million in January of 2020. Imports Intra Eu - Railway & Tram Tracks, Signals, in the United Kingdom averaged 31.44 GBP Million from 1996 until 2020, reaching an all time high of 188.95 GBP Million in September of 2016 and a record low of 2.13 GBP Million in October of 1996. This page includes a chart with historical data for the United Kingdom Imports of Intra EU - Railway & Tram Tracks, Sign.




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Gulf participation in football tournament signals thaw in Qatar relations

Decision by Saudi Arabia and UAE to send teams follows two-year boycott of gas-rich state




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Airbus signals further production cut with job losses set to follow

Plane maker’s chief warns aerospace industry in ‘gravest crisis’ as group swings to quarterly loss amid aviation collapse




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BA job cuts signal depth of crisis for airline sector

Post-Brexit Britain will need a viable industry to support global role




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Treasury market sends bearish signals as stocks rise

Two- and five-year yields hit record lows as futures investors anticipate negative rates




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Josh Constine leaves TechCrunch for VC fund SignalFire

How do you leave the place that made you? You figure out what it made you for. TechCrunch made me a part of the startup ecosystem I love. Now it’s time to put that love into action to help a new generation of entrepreneurs build their dreams and tell their stories. So it’s “TC to […]




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8 top fintech VCs discuss COVID-19 trends, signals and opportunities

In recent years, fintech’s revolution has felt like a rising tide. Behemoths like Stripe and Square edged out banks while newbies like Brex nonchalantly raised nine-figure rounds. Today, however, the state of the financial technology industry feels more wobbly — some healthy startups in the genre are faring better than ever, while others are feeling […]




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Sancho pays tribute to Kobe Bryant by signalling No 24 in goal celebration

Bryant lost his life in a helicopter crash last Sunday, which also claimed the lives of eight others, including his 13-year-old daughter Gianna. Sancho dedicated his goal to Bryant.




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Borussia Dortmund set up treatment centre inside Signal Iduna Park to help fight coronavirus

Borussia Dortmund have transformed the North Stand of their Signal Iduna Park stadium into a coronavirus treatment centre. Dortmund have given up one section of the their home to test patients.




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David de Gea signals his intention to stay at Manchester United 'for many years'

David de Gea has signalled his intention to stay as Manchester United's No.1, saying he wants to remain at Old Trafford for 'many years'.




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Priti Patel signals fresh crackdown on illegal migrants crossing English Channel

Priti Patel today signalled a fresh crackdown on illegal migrants crossing the English Channel as she also vowed to tackle 'vexatious' asylum claims.




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Software for R&S®SMW200A Vector Signal Generator




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Remote Emulation with the R&S SMBV100B Signal Generator

Remote Emulation with the R&S SMBV100B Signal Generator




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5G NR Signal Generation and Analysis




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EMC32-S: Transmission of Disturbance Signal Parameters to dAV Camera Systems

EMC32-S: Transmission of Disturbance Signal Parameters to dAV Camera Systems




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Remote Emulation with the R&S SMA100B Signal Generator

Remote Emulation with the R&S SMA100B Signal Generator




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Generation of GNSS Signals in a Hardware in the Loop (HIL) Environment

The GNSS simulators R&S®SMW200A and R&S®SMBV100B are remote-controllable in realtime and can process position coordinates, kinetic parameters, and vehicle attitude information from a HIL simulator. The R&S®SMW200A and R&S®SMBV100B update the simulated receiver position in realtime according to the HIL input commands (via SCPI or UDP).




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5G NR MIMO signal analysis

5G NR MIMO signal analysis




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Verify high frequency signal integrity on printed circuit boards

Verify high frequency signal integrity on printed circuit boards