rome Electronic Vapor Device Spirometer By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Provided are systems, methods, and electronic vapor devices configured to provide spirometer functionality and respiratory medication dispensing which can couple and function symbiotically with a portable electronic communication device. Full Article
rome MICROELECTROMECHANICAL GYROSCOPE WITH REJECTION OF DISTURBANCES AND METHOD OF SENSING AN ANGULAR RATE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A gyroscope includes a substrate, a first structure, a second structure and a third structure elastically coupled to the substrate and movable along a first axis. The first and second structure are arranged at opposite sides of the third structure with respect to the first axis A driving system is configured to oscillate the first and second structure along the first axis in phase with one another and in phase opposition with the third structure. The first, second and third structure are provided with respective sets of sensing electrodes, configured to be displaced along a second axis perpendicular to the first axis in response to rotations of the substrate about a third axis perpendicular to the first axis and to the second axis. Full Article
rome MICRO-ELECTROMECHANICAL APPARATUS HAVING CENTRAL ANCHOR By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A micro-electromechanical (MEMS) apparatus includes a substrate, two first anchors, a frame, and two elastic members. The substrate is provided with a reference point thereon. The frame surrounds the two first anchors, and each of the elastic members connects the corresponding first anchor and the frame. Each of the first anchors is disposed near the center of the MEMS apparatus to decrease an effect caused by warpage of the substrate. The MEMS apparatus can be applied to an MEMS sensor having a rotatable mass, such as a three-axis accelerometer or a magnetometer, to improve process yield, reliability, and measurement accuracy. Full Article
rome TRIPLE QUADRUPOLE MASS SPECTROMETRY COUPLED TO TRAPPED ION MOBILITY SEPARATION By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT The invention provides a method for acquiring fragment ion spectra of substances in complex substance mixtures wherein a trapped ion mobility spectrometer (“TIMS”) is used as the ion mobility separation device coupled to a triple quadrupole mass filter assembly. The fragment ion spectra may be used for the identification of high numbers of proteins in complex mixtures, or for a safe quantification of some substances, by their fragment ion mass spectra in a mass spectrometer with upstream substance separator. TIMS, in particular equipped with parallel accumulation, provides the unique possibility to prolong the ion accumulation duration to find more detectable ion species without decreasing the measuring capacity for fragment ion mass spectra. The high measurement capacity for fragment ion mass spectra permits the repeated measurement of low abundance ion species such as to improve the quality of the fragment ion spectra. Full Article
rome SPECTROMETER MODULE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A spectrometer module comprising a plurality of separate electronic circuit modules is disclosed. Each separate electronic module comprises an integrated sensor circuit including a light sensitive area occupying part of an area of the integrated sensor circuit, the integrated sensor circuit being arranged to detect incident light. In one aspect, the plurality of separate electronic circuit modules includes a group of adjacent electronic circuit modules. The light sensitive areas of the electronic circuit modules in the group are so arranged on the respective integrated sensor circuits that the group of adjacent electronic circuit modules is mounted so that the light sensitive areas thereof are arranged in vicinity to each other. The spectrometer module includes an optical module, which is common to said plurality of separate electronic circuit modules and arranged to direct incident light towards the light sensitive areas of each of said electronic circuit modules. Full Article
rome Mass Spectrometer By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A mass spectrometer is disclosed comprising a first ion trap or ion guide, a single ion mobility spectrometer or separator stage and a second ion trap or ion guide arranged downstream of the ion mobility spectrometer or separator. In a mode of operation ions from the second ion trap or ion guide are passed from the second ion trap or ion guide back upstream to the ion mobility spectrometer or separator. Full Article
rome 175: Jerome Harmon By theciphershow.com Published On :: Mon, 07 Nov 2016 08:30:00 -0500 Jerome “J-Roc” Harmon is a Grammy-winning musician and producer best-known for his work with Timbaland. He got his start in Texas, playing gospel and jazz with people like Fred Hammond, Kirk Franklin, and Wayman Tisdale, while producing the occasional hip-hop record. But once he met Timbaland about ten years ago, his career took off.Harmon has produced, co-produced, or performed on projects by Timbaland, Nas, Chris Brown, Robin Thicke, Jennifer Hudson, Justin Timberlake, Beyoncé, Jay Z, Michael Jackson, and many more. He has won Grammys for his work with gospel icon Fred Hammond, Chris Brown, Justin Timberlake, and Beyoncé, and was a key player in albums like Timberlake’s The 20/20 Experience, Jay Z’s The Blueprint 3 and Magna Carta…Holy Grail, and Beyoncé’s self-titled LP.See http://theciphershow.com/episode/175/ for full show notes and comments. Full Article
rome #566 - Yoel Romero By thechurchofwhatshappeningnow.libsyn.com Published On :: Mon, 12 Mar 2018 01:22:18 +0000 Yoel Romero, a former olympian who won the silver medal in the 2000 Olympics as a member of Cuba's wrestling team, and current #1 contender in the UFC's Middleweight division, joins Joey Diaz and Lee Syatt LIVE in studio. This podcast is brought to you by: Hims - Go to ForHims.com/joey for a trial month of everything you need to keep your hair - for just $5 while supplies last. FujiSports.com - Use promo code CHURCH for a 10% discount on all the best jiu jitsu and martial arts gear. Onnit.com. Use Promo code CHURCH for a 10% discount at checkout. Recorded live on 03/11/2018. Full Article
rome Vanley Burke photography exhibition launched at Birmingham Hippodrome By thebirminghampress.com Published On :: Sat, 18 Jan 2020 00:00:37 +0000 Augmented reality used to bring the stories behind the portraits to life. Full Article Community Exhibitions Photography Birmingham Hippodrome Friction Arts home Sandra Martin Vanley Burke
rome Glitchmachines Palindrome granular sampler plugin on sale at $19 USD By rekkerd.org Published On :: Thu, 30 Apr 2020 16:05:17 +0000 Plugin Boutique has launched an exclusive sale on the Palindrome granular morph plotting sampler by Glitchmachines, offering a 75% discount for the next few days. The basic concept behind Palindrome is to fuse four granular samplers with a coordinate plotting grid and complex modulation sources in order to facilitate the creation of morphing sound effects […] The post Glitchmachines Palindrome granular sampler plugin on sale at $19 USD appeared first on rekkerd.org. Full Article News Sales and promotions AU GlitchMachines granular morphing Plugin Boutique sale sampler VST
rome Splice launches new sounds from Mario Luciano, Nicky Romero, Josh Pan and X&G, and !llmind By rekkerd.org Published On :: Tue, 05 May 2020 14:08:18 +0000 Splice has launched some new samples and presets on its Splice Sounds label. Mario Luciano Sample Pack Vol. 2 — Musician, composer, and arranger, Mario Luciano is back with his second volume of sounds for Splice. Using 100% all-analog keyboards, instruments, and vintage mixing equipment to craft his samples, you’ll find some truly unique gems […] The post Splice launches new sounds from Mario Luciano, Nicky Romero, Josh Pan and X&G, and !llmind appeared first on rekkerd.org. Full Article News Patches and sound banks Samples and sound libraries !llmind Josh Pan Mario Luciano Nicky Romero Splice X&G
rome BookMark: "Rome: A History In Seven Sackings" By Matthew Kneale By radio.wpsu.org Published On :: Thu, 08 Aug 2019 20:00:00 +0000 History makes a great story when it’s told well. And who can resist a good story? I certainly can’t. Having been a history major in undergrad, I may be particularly susceptible. So when I came across Matthew Kneale’s new book, “Rome: A History In Seven Sackings” in the leisure reading collection at Pattee Library, I had to check it out. There are many histories of long-lived cities. Paris, London, Jerusalem and Rome have all had more than a few treatments. But every so often a writer looks at a history like this in a different way, and that makes it all the more interesting. Kneale’s choice of looking at Rome through seven different times it was conquered over the millennia is a particularly intriguing choice. Beginning with an early, brief occupation in 387 B.C. and continuing up to the Second World War, it is an engrossing tale. Organizing the history of Rome around these seven “sackings” offers fascinating snapshots of the city at specific moments in time. Together, they weave a Full Article
rome Al Letson Reveals: Jerome Corsi By beta.prx.org Published On :: Mon, 03 Dec 2018 11:00:00 -0000 Don’t miss out on the next big story. Get the Weekly Reveal newsletter today. Full Article Corsi Infowars Muller News & Politics Politics President Roger Stone Russia Special Counsel Trump ad-free adfree
rome It’s Happening Now! Pope Summons World Leaders to Rome By feedproxy.google.com Published On :: Tue, 15 Oct 2019 00:00:00 GMT This is simply stunning! The Vatican has just made an unprecedented, audacious overture for religious unity. Full Article
rome Imposter Syndrome (Rebroadcast) By kutpodcasts.org Published On :: Thu, 27 Jul 2017 22:39:10 +0000 Most people feel in over their heads when they first enter a challenging situation or even a new job. And, while conventional wisdom suggests those with trepidations about trying new things should “fake it ’til they make it,” it may not always be the best course of action. In this edition of Two Guys on... Full Article Two Guys on Your Head audio behavioral psychology dr art markman dr. bob duke human behavior Imposter syndrome podcast psychology Rebecca McInroy The Brain
rome Imposter Syndrome (Rebroadcast) By kutpodcasts.org Published On :: Fri, 30 Aug 2019 17:52:15 +0000 What is the real problem when you feel inadequate? How can you help yourself overcome it when you recognize it? In this edition of Two Guys on Your Head, Dr. Art Markman and Dr. Bob Duke talk about The Imposter Syndrome. Full Article Two Guys on Your Head #psychology #podcast #audio #writersblock audio comedy Imposter syndrome Science
rome Imposter Syndrome (Rebroadcast) By kutpodcasts.org Published On :: Sun, 16 Feb 2020 15:37:29 +0000 In this edition of Two Guys on Your Head, Dr. Art Markman, and Dr. Bob Duke, talk about The Imposter Syndrome. What is the real problem when you feel inadequate? How can you help yourself overcome it when you recognize it? Full Article Two Guys on Your Head comedy Imposter syndrome podcast psychology The Brain
rome Child in New York dies; syndrome tied to coronavirus is suspected By www.seattletimes.com Published On :: Fri, 08 May 2020 13:45:35 -0700 NEW YORK — A child died in a Manhattan hospital on Thursday from what appeared to be a rare syndrome linked to the coronavirus that causes life-threatening inflammation in critical organs and blood vessels of children, the hospital said. If confirmed, it would be the first known death in New York related to the mysterious […] Full Article Health Nation Nation & World Nation & World Politics World
rome 3 NY children die from syndrome possibly linked to COVID-19 By www.seattletimes.com Published On :: Sat, 09 May 2020 06:55:26 -0700 NEW YORK (AP) — Three children have now died in New York state from a possible complication from the coronavirus involving swollen blood vessels and heart problems, Gov. Andrew Cuomo said Saturday. At least 73 children in New York have been diagnosed with symptoms similar to Kawasaki disease — a rare inflammatory condition in children […] Full Article Health Nation
rome 3 NY children die from syndrome possibly linked to COVID-19 By www.seattletimes.com Published On :: Sat, 09 May 2020 06:55:26 -0700 NEW YORK (AP) — Three children have now died in New York state from a possible complication from the coronavirus involving swollen blood vessels and heart problems, Gov. Andrew Cuomo said Saturday. At least 73 children in New York have been diagnosed with symptoms similar to Kawasaki disease — a rare inflammatory condition in children […] Full Article Health Nation
rome 3 NY children die from syndrome possibly linked to COVID-19 By www.seattletimes.com Published On :: Sat, 09 May 2020 06:55:26 -0700 NEW YORK (AP) — Three children have now died in New York state from a possible complication from the coronavirus involving swollen blood vessels and heart problems, Gov. Andrew Cuomo said Saturday. At least 73 children in New York have been diagnosed with symptoms similar to Kawasaki disease — a rare inflammatory condition in children […] Full Article Health Nation
rome 3 NY children die from syndrome possibly linked to COVID-19 By www.seattletimes.com Published On :: Sat, 09 May 2020 06:55:26 -0700 NEW YORK (AP) — Three children have now died in New York state from a possible complication from the coronavirus involving swollen blood vessels and heart problems, Gov. Andrew Cuomo said Saturday. At least 73 children in New York have been diagnosed with symptoms similar to Kawasaki disease — a rare inflammatory condition in children […] Full Article Health Nation
rome Mystery Inflammatory Syndrome In Kids And Teens Likely Linked To COVID-19 By www.npr.org Published On :: Thu, 07 May 2020 08:00:00 -0400 Doctors in the U.S. and Europe are reporting a small wave of cases of what looks like a "shock syndrome" in young people. They have low blood pressure, inflamed hearts and other serious symptoms. Full Article
rome WHARTON, E.: Ethan Frome (Unabridged) (NA0421) By www.naxos.com Published On :: Wed, 29 Apr 2020 00:00:00 GMT Set deep in the remote countryside of Massachusetts, New England, in a world of small-town prejudice, pettiness and rural poverty, the story of Ethan Frome explores the crippling marriage of a young man to an older woman and his love for her vibrant young cousin, Mattie, who lives as a dependent in the Frome household. His feelings lead to a day of explosive emotions with tragic consequences. Published in 1911, two years before Wharton divorced her husband, the novel integrates the raw experiences of the author’s own life to create a powerful tale of the tragic destruction of innocent love, in a stark, compressed and unified form. Over time, the book has gained the reputation of being Edith Wharton’s best work. Full Article
rome SHAKESPEARE, W.: Romeo and Juliet (Royal Shakespeare Company, 2018) (NTSC) (OA1291D) By www.naxos.com Published On :: Sun, 01 Sep 2019 00:00:00 GMT Full Article
rome PROKOFIEV, S.: Romeo and Juliet [Ballet] (Zürich Ballet, 2019) (NTSC) (ACC-20484) By www.naxos.com Published On :: Fri, 01 May 2020 00:00:00 GMT Full Article
rome PROKOFIEV, S.: Romeo and Juliet [Ballet] (Zürich Ballet, 2019) (Blu-ray, Full-HD) (ACC-10484) By www.naxos.com Published On :: Fri, 01 May 2020 00:00:00 GMT Full Article
rome PROKOFIEV, S.: Romeo and Juliet [Ballet] (Ural Opera Ballet, 2019) (NTSC) (BAC180) By www.naxos.com Published On :: Fri, 01 May 2020 00:00:00 GMT Full Article
rome PROKOFIEV, S.: Romeo and Juliet [Ballet] (Ural Opera Ballet, 2019) (Blu-ray, Full-HD) (BAC580) By www.naxos.com Published On :: Fri, 01 May 2020 00:00:00 GMT Full Article
rome What do we know about Kawasaki syndrome and COVID-19? By www.abc.net.au Published On :: Thu, 30 Apr 2020 18:06:00 +1000 As debate about when schools should resume face-to-face teaching continues, there are new concerns about what impact COVID-19 can have on children after they've recovered from the virus. Full Article
rome Prometheus By www.abc.net.au Published On :: Fri, 08 Jun 2012 09:11:00 +1000 Ridley Scott returns to the world of science fiction with a bold, visually stunning film that offers some surprises and raises lots of questions. Full Article ABC Local northqld Arts and Entertainment:Film (Movies):All Australia:QLD:Townsville 4810
rome Prometheus By www.abc.net.au Published On :: Thu, 14 Jun 2012 14:00:00 +1000 If you thought the first Alien (or the third for that matter) was scary and out of control... strap yourself in! Full Article ABC Local hobart Arts and Entertainment:Film (Movies):Action Arts and Entertainment:Film (Movies):Science Fiction Australia:TAS:All Australia:TAS:Hobart 7000
rome To Rome With Love By www.abc.net.au Published On :: Fri, 02 Nov 2012 11:03:00 +1000 The famed director's Roman holiday is Woody Allen-lite, but still manages to be sweet. Full Article ABC Local northqld Arts and Entertainment:Film (Movies):All Australia:QLD:Townsville 4810
rome Brain Hub discusses motion sickness and symptoms of little-known disease Mal de Debarquement Syndrome By www.abc.net.au Published On :: Thu, 22 Aug 2019 06:56:00 +1000 Do you suffer from an indescribable feeling of vertigo, constant dizziness and motion sickness? Chances are you could have Mal de Debarquement Syndrome. Full Article ABC Illawarra sydney illawarra Health:All:All Health:Mental Health:All Health:Women's Health:All Lifestyle and Leisure:All:All Australia:NSW:Sydney 2000 Australia:NSW:Wollongong 2500
rome A Canberra boy's life with Tourette syndrome By www.abc.net.au Published On :: Tue, 07 May 2019 14:46:00 +1000 Marc was eight-years-old when he became suicidal because of his Tourette syndrome, but he says, now at a new school, he's on a mission to help his classmates understand the often mischaracterised disorder. Full Article ABC Local canberra Health:All:All Health:Diseases and Disorders:All Australia:ACT:Canberra 2600 Australia:All:All
rome Irlen syndrome, the condition medical experts say doesn't exist, promoted to school teachers By www.abc.net.au Published On :: Wed, 26 Jun 2019 12:33:00 +1000 According to medical experts, a condition that requires coloured glasses does not exist, yet WA and NSW teachers have attended training sessions on it. Full Article ABC Goldfields goldfields Education:Schools:All Health:All:All Health:Child Health and Behaviour:All Health:Ethics:All Health:Medical Research:All Australia:NSW:All Australia:WA:All Australia:WA:Kalgoorlie 6430
rome Josh Meredith's small business is helping change community attitudes about Down syndrome By www.abc.net.au Published On :: Thu, 18 Apr 2019 12:09:00 +1000 Josh Meredith lives with Down syndrome and is helping change community attitudes towards disability in the workplace. Full Article ABC Goulburn Murray goulburnmurray Business Economics and Finance:Small Business:All Community and Society:All:All Community and Society:Careers:All Community and Society:Carers:All Community and Society:Community Organisations:All Community and Society:Family and Children:Family Community and Society:Family and Children:Parenting Community and Society:Regional:All Community and Society:Work:All Health:Diseases and Disorders:Genetic disorders Human Interest:All:All Human Interest:People:All Australia:NSW:Albury 2640 Australia:VIC:Wodonga 3690
rome Guessous v. Chrome Hearts, LLC By feeds.findlaw.com Published On :: 2009-12-01T08:00:00+00:00 (California Court of Appeal) - In plaintiff's suit against defendant for infringement of jewelry designs, trademarks and copyrights, trial court's decision denying plaintiff's motion to strike defendant's complaint under the anti-SLAPP statute is affirmed as the filing of a lawsuit in a foreign country is not protected activity under the United States or California Constitutions as to implicate the statute. Full Article Civil Procedure Contracts Copyright Intellectual Property Trade Dress Trademark
rome Erbe Elektromedizin GmbH v. Canady Tech. LLC By feeds.findlaw.com Published On :: 2010-12-09T08:00:00+00:00 (United States Federal Circuit) - In a patent infringement suit involving three competitor companies that create argon gas-enhanced electrosurgical products for electrosurgery, judgment of the district court is affirmed where: 1) because the district court's construction of "low flow rate" is correct, and because there is no evidence that the accused probes infringe the asserted claims in the '745 patent, the district court's judgment of non-infringement is affirmed; 2) district court correctly granted summary judgment against plaintiff as to its trademark and trade dress claims based on the court's determination that the color blue is functional and has not acquired the requisite secondary meaning; 3) the district court properly granted summary judgment on defendant's antitrust counterclaims in favor of the plaintiffs as the "Sham litigation" exception to the Noerr-Pennington doctrine is not warranted in this case because the record demonstrates that plaintiff had probable cause to bring this patent enforcement litigation, and defendant failed to meet its burden of seeking discovery on its antitrust claims and failed to establish some genuine issue of material fact as to the other predatory acts is argues the district court ignored Full Article Antitrust & Trade Regulation Civil Procedure Intellectual Property Patent Trade Dress Trademark
rome Romero v. Brown By feeds.findlaw.com Published On :: 2019-08-29T08:00:00+00:00 (United States Fifth Circuit) - Partially affirmed, partially reversed. The removal of children from a home under investigation for abuse did not result in substantive due process violation, but did result in procedural due process rights violation. Full Article Civil Procedure Constitutional Law
rome Romero v. Brown By feeds.findlaw.com Published On :: 2019-08-29T08:00:00+00:00 (United States Fifth Circuit) - Partially affirmed, partially reversed. The removal of children from a home under investigation for abuse did not result in substantive due process violation, but did result in procedural due process rights violation. Full Article Civil Procedure Constitutional Law
rome Romero v. Provide Commerce, Inc. By feeds.findlaw.com Published On :: 2018-10-03T08:00:00+00:00 (United States Ninth Circuit) - Vacated an award of attorney fees but otherwise affirmed the district court's approval of a class action settlement resolving claims that an online retailer enrolled consumers in a membership rewards program without their consent and mishandled their billing information. Held that the district court should not have counted the full face value of $20 coupons provided to class members when it performed the percentage-of-recovery and lodestar calculations. Full Article Class Actions Attorney's Fees Consumer Protection Law
rome True or False: 90% of Babies with Down Syndrome are Aborted By www.christianitytoday.com Published On :: A new study demonstrates the role of culture in welcoming children with Down syndrome. For years, I have read news headlines in Christian and secular outlets, from conservatives and liberals alike, stating that “90% of babies with Down syndrome are aborted.” As I have argued before, and as a new study demonstrates, it’s just not true. Correcting this common misconception matters both in providing accurate information to pregnant women and in normalizing the experience of receiving a child with Down syndrome. Last week, the American Journal of Medical Geneticspublished a study about the birth rates of babies with Down syndrome in the United States. The study estimates live births of babies with Down syndrome from 1900-2010, with a focus upon the effect of prenatal screening programs within the United States on the population of babies with Down syndrome. After factoring in the expected number of live births, miscarriages, and stillbirths, it then posits a “reduction rate.” This reduction rate demonstrates the number of babies with Down syndrome that are not born as a result of selective abortion. To be specific, in 2006-2010 theses researchers estimate around 5,300 babies were born with Down syndrome annually. During this same time period, approximately 3,100 babies with Down syndrome were selectively aborted each year. Around 800 of those aborted babies would have died before birth, so without selective abortion, the researchers estimate there would be around 7,600 live births with Down syndrome. The reduction rate of babies with Down syndrome in the United States in 2010 was around 30 percent. In other words, without selective abortion, the number of babies born with Down syndrome in recent years would have been about 30 percent higher than it actually has been. So why ...Continue reading... Full Article
rome When in Rome … stay indoors during the coronavirus pandemic, or else By feeds.denverpost.com Published On :: Wed, 08 Apr 2020 17:18:20 +0000 There are 350 different varieties of pasta. If my coronavirus lockdown in Italy lasts much longer, I may try them all. Full Article Latest News Travel commentary coronavirus health The Know
rome Fake crypto-wallet extensions appear in Chrome Web Store once again, siphoning off victims' passwords By go.theregister.co.uk Published On :: Wed, 06 May 2020 20:55:29 GMT 'Seriously sometimes seems Google's moderators are only optimized to respond to social media outrage' Three weeks after Google removed 49 Chrome extensions from its browser's software store for stealing crypto-wallet credentials, 11 more password-swiping add-ons have been spotted – and some are still available to download.… Full Article
rome As coronavirus catches tech CEOs with their pants down, IBM's Ginni Rometty warns of IT's new role post-pandemic By go.theregister.co.uk Published On :: Thu, 07 May 2020 18:35:05 GMT Middle management is about to learn just how necessary they are Last night, one of the most senior figures in the IT industry from one of the biggest companies gave the strongest indication that when COVID-19 lockdowns gradually begin to lift, people will not return to the jobs they once had. That means both tech jobs, and how technology supports other business roles.… Full Article
rome Posttreatment Lyme disease syndromes: distinct pathogenesis caused by maladaptive host responses By www.jci.org Published On :: Full Article
rome Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice By www.jci.org Published On :: The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Although gene-environment interactions have been implicated in the etiology of several disorders, the impact of paternal and/or maternal metabolic syndrome on the clinical phenotypes of offspring and the underlying genetic and epigenetic contributors of NAFLD have not been fully explored. To this end, we used the liver-specific insulin receptor knockout (LIRKO) mouse, a unique nondietary model manifesting 3 hallmarks that confer high risk for the development of NAFLD: hyperglycemia, insulin resistance, and dyslipidemia. We report that parental metabolic syndrome epigenetically reprograms members of the TGF-β family, including neuronal regeneration–related protein (NREP) and growth differentiation factor 15 (GDF15). NREP and GDF15 modulate the expression of several genes involved in the regulation of hepatic lipid metabolism. In particular, NREP downregulation increases the protein abundance of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and ATP-citrate lyase (ACLY) in a TGF-β receptor/PI3K/protein kinase B–dependent manner, to regulate hepatic acetyl-CoA and cholesterol synthesis. Reduced hepatic expression of NREP in patients with NAFLD and substantial correlations between low serum NREP levels and the presence of steatosis and nonalcoholic steatohepatitis highlight the clinical translational relevance of our findings in the context of recent preclinical trials implicating ACLY in NAFLD progression. Full Article
rome Видео: Супруги Райкконен в новой рекламе Alfa Romeo By www.f1news.ru Published On :: Sat, 09 May 2020 14:36:00 +0300 В Италии жизнь понемногу возвращается в нормальное русло, и не случайно именно в эти дни компания Alfa Romeo представила новый рекламный ролик, посвящённый флагманскому кроссоверу Stelvio Quadrifoglio, где в главной роли мы видим Кими Райкконена... Full Article
rome Žebříček nejlepších spořicích účtů se totálně proměnil, sazby padají By www.idnes.cz Published On :: Mon, 27 Apr 2020 22:00:00 GMT Kvůli koronavirové pandemii lze očekávat silnou recesi. Česká národní banka proto v březnu dvakrát snížila základní úrokovou sazbu z 2,25 procenta na jedno procento. Některé banky na to už zareagovaly razantním snižováním úrokových sazeb na spořicích účtech, což zamíchalo žebříčkem nejlepších spořicích účtů. Ve spolupráci s Finparádou jsme zmapovali aktuální trend a sestavili nový žebříček. Full Article Finance - Banky a spoření