guide

Tour Guide at Medieval Manor House Discovers Mysterious Etchings Meant to Repel Evil, Trap Demons and Curse Enemies

A "staggering array" of markings have been hiding in plain sight carved into the walls of Gainsborough Old Hall, a 500-year-old home in Lincolnshire, England




guide

Validating Single-Guide RNA for Aedes aegypti Gene Editing

Creating transgenic mosquitoes allows for mechanistic studies of basic mosquito biology and the development of novel vector control strategies. CRISPR–Cas9 gene editing has revolutionized gene editing, including in mosquitoes. This protocol details part of the gene editing process of Aedes aegypti mosquitoes via CRISPR–Cas9, through testing and validating single-guide RNAs (sgRNAs). Gene editing activity varies depending on the sequence of sgRNAs used, so validation of sgRNA activity should be done before large-scale generation of mutants or transgenics. sgRNA is designed using online tools and synthesized in <1 h. Once mutants or transgenics are generated via embryo microinjection, sgRNA activity is validated by quick genotyping polymerase chain reaction (PCR) and DNA sequencing.




guide

Design and Validation of Guide RNAs for CRISPR-Cas9 Genome Editing in Mosquitoes

CRISPR–Cas9 has revolutionized gene editing for traditional and nontraditional model organisms alike. This tool has opened the door to new mechanistic studies of basic mosquito biology as well as the development of novel vector control strategies based on CRISPR–Cas9, including gene drives that spread genetic elements in the population. Although the promise of the specificity, flexibility, and ease of deployment CRISPR is real, its implementation still requires empirical optimization for each new species of interest, as well as to each genomic target within a given species. Here, we provide an overview of designing and testing single-guide RNAs for the use of CRISPR-based gene editing tools.




guide

SolidWorks Holiday Gift Guide

3D Design-Inspired Gifts for Everyone on Your List




guide

2024 Mac Buyer's Guide -- Which desktop Mac you should buy?

Following the introduction of new Mac models in October, Apple has shaken up its desktop Mac roster. Here's what you should buy, at just about any price point.


Apple's current crop of desktop Macs

Price is an important factor when choosing your next Mac. The more budget that you have available, the better the Mac you can get.

However, while Apple does cover a wide array of price points, it also has multiple choices available for many of them. Add in the number of configurable elements, and it can become a bewildering decision.


Continue Reading on AppleInsider | Discuss on our Forums




guide

Ultimate guide on how to use an external SSD as a working drive on macOS Sequoia

It is easily possible to double the cost of a new M4 Mac mini by buying Apple storage — but if you know what you're doing, you can buy external drives, and save hundreds of dollars by working off those. Here's how.


External drives are vastly cheaper than Apple's storage upgrade prices

Apple's New Mac mini is a stunning bargain for its price and its performance — but maybe only in its base configuration. Once you start adding anything like more storage, you hit Apple's excessive upgrade charges and the bargain diminishes, or even goes away entirely.

It is true that Apple has made things better, both by increasing the amount of RAM that base model gets, and also by making 256GB the smallest amount of storage you can buy.


Continue Reading on AppleInsider | Discuss on our Forums




guide

Holiday 2024 MacBook Buyer's Guide -- Which Mac laptop you should buy?

Apple's late 2024 update to its Mac and MacBook ranges has brought M4 to the product line. Here's how to choose the best portable Mac for your budget for the 2024 holiday season.


MacBook Air and MacBook Pro

Apple's fall product updates covered many areas, but for the Mac product category, it meant an update to M4. Following the introduction of the chip in the iPad Pro lineup earlier in the year, the MacBook Pro now uses the speedy chip.

Even better, Apple didn't stop at just M4, as it brought out M4 Pro and M4 Max variants as well. These additions offer a lot more performance options, and in the case of the M4 Max, more performance than an M2 Ultra in some benchmarks.


Continue Reading on AppleInsider | Discuss on our Forums




guide

Cognitively-Guided Instruction: Supporting Students to Create Their Own Mathematical Understanding

A student-centered approach to teaching mathematics enables students to develop conceptual understanding and to grow as confident mathematicians.




guide

Virtual IEP Meetings: A 6-Step Guide for Parents and Teachers

A new resource offers tips on how to keep Individualized Education Program meetings focused and on-schedule.




guide

Abington faculty's new textbook guides human services majors through internships

Penn State Abington rehabilitation and human services faculty Abigail Akande, Stacey Conway and Michael Lavetsky wrote a recently published book, "Experiential Learning and Internship for Undergraduates: A Workbook for Undergraduate Interns in the Human Services Field," to help guide human services students at Abington and other Penn State campuses through the internship and career development and exploration processes. 




guide

Motivation and commitment guide this World Campus grad’s journey

Army veteran Eddie Brown never thought he’d earn a college degree. Years after leaving the Army, he graduated from Penn State World Campus, earning a bachelor of arts in labor and human resources.




guide

Delaware Mortgage Relief Program Announces New Program Guidelines And Partnerships

Homeowners Can Now Receive Up To $50,000 In Financial Assistance, Including Future Payments and Non-Delinquent Mortgage Payments. Dover, Del. January 11, 2022 – The Delaware State Housing Authority (DSHA) announced today updates to the Delaware Mortgage Relief Program, which include the following: Removing the requirement of 30-day mortgage Homeowners who do not have a delinquent […]



  • Delaware State Housing Authority
  • News
  • FAQ
  • Mortgage Relief Program

guide

Top Court Verdict Tomorrow On Pan-India Property Demolition Guidelines

The Supreme Court is scheduled to pronounce its verdict on Wednesday on pleas seeking framing of guidelines on the demolition of properties in the country.




guide

Top Court Verdict Tomorrow On Pan-India Property Demolition Guidelines

The Supreme Court is scheduled to pronounce its verdict on Wednesday on pleas seeking framing of guidelines on the demolition of properties in the country.




guide

Big Supreme Court Verdict On 'Bulldozer Justice' Today, Pan-India Guidelines Expected

After making strong observations on the practice of demolishing houses of criminals to send out a strong message against crime, which has come to be known as 'bulldozer justice', the Supreme Court is expected to issue a set of pan-India guidelines fo




guide

"Officials To Pay From Salary": Top Court Guidelines On 'Bulldozer Justice'

The Executive cannot replace the Judiciary and legal process should not prejudge the guilt of an accused, the Supreme Court said today, taking a tough stand on the issue of 'bulldozer justice'.




guide

"Officials To Pay From Salary": Top Court Guidelines On 'Bulldozer Justice'

The Executive cannot replace the Judiciary and legal process should not prejudge the guilt of an accused, the Supreme Court said today, taking a tough stand on the issue of 'bulldozer justice'.




guide

Centre Bans 'Dark Patterns' On E-Commerce Platforms; Notifies Guidelines

In order to protect consumers' interest, the government has banned use of "dark patterns" on e-commerce platforms which intend to deceive customers or manipulate their choices.





guide

Delaware Heritage Commission Book of the Week is Delaware: A Guide to the First State

Originally written by the Federal Writers Project as part of their classic “American Guide” series, this reprint depicts history, life, travel, and recreation in Delaware as it was in 1938. Including a full-size replica of the original tour map, this comprehensive guide includes art and engravings of various historic locations, dozens of vintage photos, and […]



  • Delaware Heritage Commission
  • Delaware Public Archives

guide

The DE Dept. of Labor Releases Fraud Prevention Guidelines

  For Immediate Release Thursday, May 28, 2020. Wilmington, DE The Delaware Department of Labor releases Fraud Prevention guidelines for employers and claimants to protect against identity theft and fraud involving unemployment benefits during the COVID-19 pandemic.   Over the past few weeks, several states have reported incidents of identity theft and payment fraud regarding […]




guide

The Delaware Department of Labor Issues Guidelines for Employers and Employees Regarding Returning to Work.

For Immediate Release July 22, 2020 Contact: Kenneth Briscoe Director of Communications Kenneth.Briscoe@delaware.gov   (Wilmington, DE) –  PHASE 2 of Governor John Carney’s Economic Reopening plan began on June 15, 2020. During this rolling reopening of the state’s economy, the restrictions put in place by Governor Carney in March 2020 to reduce the spread of […]



  • Department of Labor

guide

Department of Labor Releases New Fraud Prevention Guidelines for Employers and Claimants

WILMINGTON, Delaware – The Delaware Department of Labor (DOL) has re-released Fraud Prevention guidelines for employers and claimants to protect against identity theft and fraud involving unemployment insurance benefits as incidence of new consumer scams increase across the country. In recent months, the U.S. Federal Trade Commission (FTC) has received multiple reports of scams where […]




guide

Focus Group Insights Help Guide Future Enhancements to Family Caregiver Services at DHSS

NEWARK (Nov. 14, 2022) – The Division of Services for Aging and Adults with Physical Disabilities (DSAAPD) is using the findings from a report based on caregiver focus groups held late last year across the state to enhance its current supports and develop a new approach to caregiver services. This includes the formation of the […]







guide

Through the years: SAS Enterprise Guide versions

My colleague Rick Wicklin maintains a nifty chart that shows the timeline of SAS releases since Version 8. A few of you asked if I could post a similar chart for SAS Enterprise Guide. Here it is. Like Rick, I used new features in SAS 9.4 to produce this chart [...]

The post Through the years: SAS Enterprise Guide versions appeared first on The SAS Dummy.




guide

DNREC Announces Arrival of 2024/25 Delaware Hunting and Trapping Guide

With new Delaware hunting licenses going on sale this week, DNREC announced the 2024/25 Delaware Hunting and Trapping Guide is now available in hard copy from license agents throughout the state, at DNREC's recreational licensing office in the Richardson & Robbins Building at 89 Kings Highway in Dover and in a readily referenced online edition.




guide

Here’s how you can activate your SBI debit card online: A step-by-step guide

Any State Bank of India account holder in order to activate their ATM card or a debit card can go to the online portal of SBI and do so by clicking on the e-services tab.




guide

A Guide to Build A Mini Guitar/Audio Amplifier Based on LM386

Hey, is it suitable to post here? I wanted a small yet robust amp for practicing while I travel. I wanted something that would fit in my pocket yet still be loud enough to hear.

Presented here is a amplifier based upon the LM386 Audio Amplifier.

There is a standard circuit in the data sheet that is an excellent place to start.

Materials needed:
1 - HM359 project box
1 - 668-1237 speaker
1 - BS6I battery conn
1 - CP1-3515 stereo jack
1 - SC1316 stereo jack
2 - 450-1742 knob
1 - 679-1856 switch
1- 3mm LED
1 - 10 ohm 1/4W resistor
1 - 10uF ceramic cap
1 - .05 uF ceramic cap
1 - 420 uF electrolytic cap
1 - 8 ohm resistor
2 - 51AADB24 10K pot
1 - HM1252 circuit board
1 - LM386N-4 amplifier

Wire and Solder
Step 1: Prep the enclosure

Careful planning is required the first time you free build a circuit. The circuit board has solder pads but not traces. You will have to use thin wire to make the connections for the circuit to work.

Begin by laying out the components on the circuit board that will need to pass through the enclosure. This enclosure has a removable top panel which will be used for the volume, gain and 1/4 inch stereo jack.

Space is limited to check for fit before drilling.

All drilling of the plastic should be done with a step drill bit. This will make the cleanest holes without breaking the plastic.

Lay out the pots a few spaces back but still in line with the desired position. mark the center of each pot shaft then drill with a step drill tot he tightest fitting hole size. Make a center mark between the pot holes then drill for the stereo jack

On the inside of the top cover position and mark where the speaker will go.

Make a template on grid paper the same size as the speaker.

Tape the template to the inside of the cover as shown then use a step bit to drill holes on the center of every square in the grid. This will form the speaker grille. clean up the holes.

Step 2: place the major components

Solder the pots to the circuit board as shown. then place the stereo jack(note in order to get the final fit I had to trim and modify the stereo jack housing a little)

Next, position and solder the switch on the circuit board and mark a space on the top cover that will need to be cut for the switch opening. Use a small file to cut the opening.

Use a sharp knife to bevel the edges of the switch hole to allow for easier operation.

Drill a hole in the side of the upper case for the headphone jack and fasten it in place. ( I had to recess the hole a bit for the retaining nut to grab)

Step 3: Build the circuit

The speaker is held in place by using 2 small brackets that come with the serial cable connector hood. ( I had a bunch around that would never be used)

Refer the the circuit shown from the datasheet and the datasheet for the LM386. The basic circuit only has the volume control while the datasheet shows how to add a gain control across pins 1 and 8 of the amplifier.

The speaker is wired in series with the headphone jack. The headphone jack has internal switches that shut the speaker off when the phones are plugged in.

I chose to use a chip socket for the amplifier which make prototyping easier since you do not have to worry about solder heating as much.

Carefully lay the circuit out on the board and begin wiring components together. I added a second pot and cap in series between pins 1 and 8 of the amp to be able to manually set the gain in addition to volume.

Check you connections with a multimeter before adding the amplifier.

I chose to add a LED indicator for power. This was done by using one side of switch contacts from the battery. The LED is in series with a 220 ohm resistor.

Assemble the case and insert the battery.

Step 4: Final notes

If the speaker is noisy while the headphones work normally, try reversing the speaker connections. If it does not correct the issue, connect a 8 ohm resistor across the speaker contacts.

You may have to place an insulating layer between the speaker and the place where the stereo jack comes through to prevent contact. This will be noted by a loud buzz.

You may have to add some foam in the battery compartment to stop the battery from banging around.

For reference, I've also read an article about amplifiers: http://www.apogeeweb.net/article/60.html

Thanks for reading!




guide

Technical Webinar: A Beginner’s Guide to RTL-to-GDSII Front-End Flow

In this training webinar, we explore the concepts of RTL design, design verification, and coverage analysis while unveiling the exciting world of front-end design flow. We will guide you through the essential steps in creating integrated circuits, the building blocks of modern electronics.

We’ll break down the process into manageable stages, from defining the chip’s functionality to its physical realization. We’ll investigate the front-end part of the RTL-to-GDSII flow—from specification to functional verification and design coverage—and explore:

  • Key concepts of specifying chip behavior and performance
  • How to translate ideas into a digital blueprint and transform that into a design
  • How to ensure your design is free of errors

This webinar provides practical knowledge, making it your gateway to understanding the magic behind RTL-to-GDSII front-end design flow.

When Is the Webinar?

Date and Time

Wednesday, September 18, 2024
07:00 PDT San Jose / 10:00 EDT New York / 15:00 BST London / 16:00 CEST Munich / 17:00 IDT Jerusalem / 19:30 IST Bangalore / 22:00 CST Beijing 

REGISTER

To register for this webinar, sign in with your Cadence Support account (email ID and password) to log in to the Learning and Support System.

Then select Enroll to register for the session. Once registered, you’ll receive a confirmation email containing all login details.

If you don’t have a Cadence Support account, go to Cadence User Registration and complete the requested information. Or visit Registration Help.

For inquiries or issues with registration, reach out to eur_training@cadence.com.

For inquiries or issues with registration, reach out to eur_training@cadence.com.

To view our complete training offerings, visit the Cadence Training website.

Want to share this and other great Cadence learning opportunities with someone else? Tell them to subscribe.

Want to Learn More?

This link gives you more information about the related training course and a link to enroll:

Cadence RTL-to-GDSII Flow Training

The course includes slides with audio and downloadable laboratory exercises designed to emphasize the topics covered in the lecture. There is also a Digital Badge available for the training.

 

The online class is free for all Cadence customers with a Cadence Learning and Support Portal account. For instructor-led training sessions "Live" or "Blended" please contact Cadence Training.

Also, take this opportunity to register for the free Online Trainings related to this webinar topic.

Cadence RTL-to-GDSII Flow

Xcelium Simulator

Verilog Language and Application

Xcelium Integrated Coverage

Related Training Bytes

How to Run the Synthesis Without DFT?

How to Run the Synthesis Flow with DFT? (Video)

Related Blogs

Did You Miss the RTL-to-GDSII Webinar? No Worries, the Recording Is Available!

Training Insights – Why Is RTL Translated into Gate-Level Netlist?

Training Bytes: They May Be Shorter, But the Impact Is Stronger!

Cadence Support - A Round-the-Clock Problem Solver, Webinar Recording Available!




guide

Embrace self-love this Singles Day: a guide to celebrating you




guide

3525 operation guide

3525 operation guide




guide

6300 user guide

6300 user guide




guide

10bii business calculator user guide

10bii business calculator user guide




guide

3600 user guide

3600 user guide




guide

bladecenter c7000 configuration guide

bladecenter c7000 configuration guide




guide

37717c quick manual start guide user guide

37717c quick manual start guide user guide




guide

1220c printer user guide

1220c printer user guide




guide

13printer user guide

13printer user guide




guide

5500 printer guide

5500 printer guide




guide

alm administrator guide

alm administrator guide




guide

bladesystem c7000 enclosure setup and installation guide

bladesystem c7000 enclosure setup and installation guide




guide

8013a service user guide

8013a service user guide




guide

36user guide

36user guide




guide

alm performance center installation guide

alm performance center installation guide




guide

8971c service manual user guide

8971c service manual user guide




guide

halasz gl1100 carburetor repair guide

halasz gl1100 carburetor repair guide




guide

401user guide

401user guide