Medicinal chemists focus on the main protease of SARS-CoV-2 to develop antiviral treatments for the virus causing COVID-19

Medicinal chemists focus on the main protease of SARS-CoV-2 to develop antiviral treatments for COVID-19

Has your local store run out of sanitizing wipes? This cheat sheet can help you find and understand alternatives

Technique modifies subsets of cells and frees gene editing proteins for potential further improvements

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Dewey Library - QC773.3.U5 M262 2020

As per UNESCO estimates, over 154 crore students are severely impacted by closure of educational institutions across the world amid the COVID-19 outbreak.

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Dugan, Frank M., 1947-

Littler, Diane Scullion

Davis, Holly, 1951-

Fuhrer, B. A. (Bruce Alexander), 1930-

Moore, D. (David), 1942-

Stephenson, Frank Harold

Lebrun, Jean-Luc

Pechenik, Jan A

Clymo, R. S., author

Oster, Sandra, 1949- author

Roldan, Leslie, author

Illingworth, Sam, author

Boxman, R. L., author

Asks officers to fact-check and refer to reliable sites to verify news reports

The guidance contained detailed advice for making site-specific decisions related to reopening schools, restaurants, summer camps, churches, day care centers and other institutions

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Coming out of these unusual times financially fitter and stronger would require discipline, perseverance, conservancy tricks and fortitude. Here are some handy tips for millennials

Interview with Paul A. James, MD, author of 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)

Interview with Ann Marie Navar-Boggan, MD, PhD, author of Proportion of US Adults Potentially Affected by the 2014 Hypertension Guideline

Interview with Nancy L. Keating, MD, MPH, author of A Systematic Assessment of Benefits and Risks to Guide Breast Cancer Screening Decisions

Interview with Rupert M. Pearse, MD, author of Effect of a Perioperative, Cardiac Output-Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery: A Randomized Clinical Trial and Systematic Review

Interview with Elizabeth T. H. Fontham, MPH, DrPH, author of Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society, Nancy L. Keating, MD, MPH, author of New Guidelines for Breast Cancer Screening in US Women, and Evan R. Myers, MD, MPH, author of Benefits and Harms of Breast Cancer Screening: A Systematic Review

The 2015-2020 US Dietary Guidelines for Americans were recently released. They are intended to provide guidance for health policy officials and clinicians regarding healthy diets and establishing goals for improving nutrition. These are important since bad eating habits are the underlying cause for a great deal of disease in the US and that these guidelines influence the operations of programs such as school lunch assistance, meals on wheels etc. Because these guidelines influence policy, they have been criticized by various investigators and special interest groups. Karen DeSalvo, MD, Acting Assistant Secretary for Health at HHS and author of Dietary Guidelines for Americans responds to some of these criticisms and explains how the guideline was created and what it is intended to do. Implementation of the guidelines dietary advice may be challenging and Deborah Clegg, RD, PhD, Professor of Internal Medicine at UCLA discusses how the various recommendations can be followed.

In 2017 the Society for Critical Care Medicine updated its guidelines for sepsis management. These new guidelines differ significantly from ones in the past in that they no longer recommend protocolized resuscitation and emphasize early and aggressive fluid resuscitation when patients present with septic shock. This is the first podcast in the Surviving Sepsis guideline series. The next episode discusses why the new sepsis guideline changed.

Article discussed in this episode: Management of Sepsis and Septic Shock

Speakers:

Laura Evans, MD, MSc, of Bellevue Hospital and NYU Medical Center

Andrew Rhodes, MBBS, MD, of St George’s University Hospitals NHS Trust and co-chair of the Surviving Sepsis guideline panel

Mitchell M. Levy, MD, of the Alpert Medical School of Brown University and Rhode Island Hospital

Recent guidelines for how to best manage septic shock have changed. Gone are recommendations for central venous oxygen saturation monitoring and goal-directed therapy. In is the concept that septic shock be treated as an emergency with rapid administration of antibiotics and large amounts of fluids. Our discussants Derek C. Angus, MD, MPH, and Michael D. Howell, MD, MPH, discuss why these recommendations have changed. This is the second podcast in the Surviving Sepsis guideline series. The first podcast reviewed what recommendations are in the guideline itself.

Article discussed in this episode: Management of Sepsis and Septic Shock

Speakers: JAMA Associate Editor Derek C. Angus, MD, MPH, University of Pittsburgh, and Michael D. Howell, MD, MPH, University of Chicago.

Interview with Paul A. Volberding, MD, and Hyman Scott, MD MPH, authors of HIV Screening and Preexposure Prophylaxis Guidelines: Following the Evidence

Interview with Deborah Dowell, M.D., M.P.H., author of Patient-Centered Reduction or Discontinuation of Long-term Opioid Analgesics: The HHS Guide for Clinicians

Interview with Victor M. Montori, MD, MSC, author of When Guidelines Recommend Shared Decision-making