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YSRCP likely to retain local body MLC seat of Vizianagaram district

Former MLC Indukuri Raghuraju who represented the constituency previously was disqualified as YSRCP leadership approached the High Court of Andhra Pradesh with an allegation that he was indulging in anti-party activities




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Chief Minister wants to create one entrepreneur in every family in A.P., says MSME Minister

The government plans to set up incubation centres and is formulating a virtual workplace policy with incentives for people who set up workplaces, says Kondapalli Srinivas




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Your death would be mine [electronic resource] : Paul and Marie Pireaud in the Great War / Martha Hanna.

Cambridge, Mass. : Harvard University Press , 2006.




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Direct solid sample analysis of low-cost jewelry using spectroanalytical techniques: exploratory chemical data evaluation and metal migration with synthetic sweat

Anal. Methods, 2024, 16,2286-2291
DOI: 10.1039/D4AY00325J, Paper
Thaila Lorena de Araújo, Fabiola Manhas Verbi Pereira, Edenir Rodrigues Pereira-Filho
Jewelry samples were directly analyzed using LIBS and XRF.
The content of this RSS Feed (c) The Royal Society of Chemistry




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​Weather gods: On ‘Mission Mausam’

Attempts at controlling the weather are still in the realm of uncertainty




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Staunch the breach: On India, Pakistan and the Indus Waters Treaty

India and Pakistan need to drop their hard line stances on the Indus Waters Treaty




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A defeat foretold: On the Maoist insurgency

Maoists must abandon armed struggle and enter the democratic process




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Sun signs: On extreme heat and Tamil Nadu’s policy decision

States should prepare to assist the vulnerable during extreme heat events




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Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia

RSC Med. Chem., 2024, 15,3495-3506
DOI: 10.1039/D4MD00275J, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. Russell
The optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Semisynthetic phytochemicals in cancer treatment: a medicinal chemistry perspective

RSC Med. Chem., 2024, 15,3345-3370
DOI: 10.1039/D4MD00317A, Review Article
Meghna Arora, Ankit Kumar Singh, Adarsh Kumar, Harshwardhan Singh, Prateek Pathak, Maria Grishina, Jagat Pal Yadav, Amita Verma, Pradeep Kumar
Semisynthetic phytochemicals in cancer treatment.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer

RSC Med. Chem., 2024, 15,3433-3443
DOI: 10.1039/D4MD00468J, Research Article
Meijuan Liu, Na Li, Zhaoxue Wang, Shuo Wang, Shaoda Ren, Xiaojing Li
A synthetic celastrol derivative (Cel-N) attenuates cancer cell stemness, inhibits the STAT3 pathway, and exerts anti-ovarian cancer effects in cell and mouse models.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Breaking boundaries in diabetic nephropathy treatment: design and synthesis of novel steroidal SGLT2 inhibitors

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00645C, Research Article
Geetmani Singh Nongthombam, Semim Akhtar Ahmed, Kangkon Saikia, Sanjib Gogoi, Jagat Chandra Borah
Virtual screening and synthetic modification of natural product-derived steroidal precursors as potential SGLT2 inhibitors for the treatment of diabetic nephropathy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Four schools and a college in Tiruchi receive hoax bomb threats

Three schools declared a holiday on Tuesday as a precautionary measure




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Railways using treated water from its STP for maintaining green spaces

The treated water is stored in an overhead tank and used in gardens at the two railway rest houses meant for officers at Kallukuzhi near Tiruchi Railway Junction




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AIADMK ready to join hands with like-minded parties to defeat DMK: Palaniswami




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543: Zach Leatherman on Eleventy, Mastodon, Twitter, and is-land

Zach Leatherman talks with us about what's new with Eleventy, setting up on Mastodon, what's happened with Twitter, and is-land.




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598: Jen Simmons on Interop, WebKit Releases, and New CSS Features in Safari

Jen Simmons, Apple Evangelist on the Web Developer Experience team for Safari & Webkit, stops by to talk about what Interop is, and a look ahead at new CSS features in Webkit and Safari such as JPEG XL, masks, a round function, JavaScript improvements, styling form controls, content unblocks, masonry, and more!




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603: Deno, React Alternatives, and Copilot Concerns with Triple Threat Josh Collinsworth

Josh (or Jsoh) stops by to talk about his work at Deno, recent blog posts on Copilot, why Svelte is awesome and React is not, Apple and PWA, and building word games on the web.




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629: The Great Divide, Global Design + Web Components, and Job Titles

A bit of follow-up on vibe driven development and JavaScript not causing The Great Divide, writing testing automation, global design systems and web components, could PHP be used for web components, what if view transitions are going to be everywhere, and frontend engineer vs design systems engineer job titles and descriptions.




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Design to beat the heat

Keeping the air conditioner on for long will only create heat islands, says Sathya Prakash Varanashi




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‘We want our citizens to breathe fresh air’

Dr. John Keung, CEO of Singapore’s Building and Construction Authority, plans to convert 80 per cent of all buildings in his country to green buildings by 2030.




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Catalysing Indian IP creation 

How policy support and monetisation can rev up India’s innovation ecosystem



  • Science and Technology

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Delhi HC seeks CBI’s response on plea to preserve CCTV footage in coaching centre deaths




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‘Threat culture’ in Centre for West Asian Studies of JNU: former seminar coordinator

Sima Baidya also says she has lodged a complaint against the chairperson of the centre and has sought security from the university authorities as she has been intimidated




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‘No religion encourages an activity that creates pollution: SC on firecrackers

The Supreme Court wondered why the Delhi Government delayed imposition of the ban on firecrackers till October 14, when the order of ban was issued




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Lessons learnt in the hot seat

Jeff Immelt, the former CEO of GE, recounts his experience of steering the company during turbulent times




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Booming Digital Stars: 11 Inspiring Journeys from India’s Creator Economy 

Lessons from the exciting success stories of social media influencers




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From beauty parlours to farming, prisoners in India’s jails are channeling their time into creative new outlets

Some trivia from prisons across the country




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Mango output is set to increase by 14% this year; heat wave unlikely to impact yields

The total production of mangos could jump to 24 million tonnes in the 2023-24 crop year, as against 21 million tonnes in 2022-23




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Centre aims seven-fold jump in wheat procurement from Uttar Pradesh, Rajasthan, Bihar this year

“Even as the ban on outbound shipments of wheat continues, “it will be a dream for us to export now”, Food Secretary Sanjeev Chopra said.




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Mangoes in Tamil Nadu hit by excessive heat, but farmers hopeful

Farmers in Tamil Nadu are struggling with poor yield, but there is also good news with new varieties being discovered




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Budget 2024: Agriculture, Employment, Infrastructure feature in nine priorities of third NDA government

Union Budget 2024 unveils nine priorities for this financial year as Finance Minister Nirmala Sitharaman delivers her seventh budget speech in Lok Sabha




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Centre launches new system to understand cropping patterns, impact of weather

Union Agriculture Ministry launches Krishi-DSS, a digital platform providing real-time data insights for stakeholders in Indian agriculture




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Karnataka’s urban farmers champion millets to create cookies, idly mixes, pasta

Meet the farmers retailing value-added products with millets such as cookies, idly mixes, pasta, and more




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Home cooks in Thiruvananthapuram are championing artificial additive-free jams, preserves, juice, ethnic eats and more

Four home cooks in Thiruvananthapuram are turning fruits into value-added products without using artificial flavours or preservatives





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Oil & gas roadshow: New policy to create more transparency, says Pradhan




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Delhi Ganesh, a great supporting actor, is no more

Though he had acted with other actors and in a lot of films, Ganesh used to say that his roles in Kamal Haasan starrers earned him a name




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State Planning Commission in Tamil Nadu flags sector-wise impact from heat wave, calls for measures

Heat stress is repeatedly causing disruptions in ecological and economic systems, SPC report titled ‘Beating The Heat-Tamil Nadu Heat Mitigation Strategy’ said.




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BJP leader Tamilisai Soundararajan calls for ‘strong alliance of like-minded parties’ to defeat DMK in 2026

BJP’s Tamilisai Soundararajan says that it is not necessary that only parties with similar ideologies should form an alliance




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Self-consistent electrostatic formalism of bulk electrolytes based on the asymmetric treatment of the short- and long-range ion interactions

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM01174K, Paper
Sahin Buyukdagli
Internal energy of monovalent electrolytes (left) and dimensionless screening parameter of multivalent electrolytes (right).
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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How to Create a CSS-Only Toggle Button

With the growing eco-system of CSS, designers, and developers are continually seeking ways to leverage its power for interactive UI elements. One such element is the toggle button, an essential interactive component. While more complex features might require JavaScript or …




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Creating Ghost Buttons with CSS

In recent years, ghost buttons have solidified their position as a trendy and elegant element. Characterized by their transparent nature and minimalist outline, ghost buttons, also known as “empty” or “naked” buttons, offers a sleek, clean aesthetic that can improve …




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How to Create a CSS Text Embossing Effect

Embossing is a graphical effect used to give the impression that the surface of an image has been raised or pressed in. In web design, an embossed text effect can give your typography a three-dimensional look and feel, often lending …




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Create Neon Style Buttons Using CSS

CSS truly is a remarkable tool in a web designer’s toolkit, capable of bringing even the most vibrant creative visions to life. Today, we’re immersing ourselves in the radiant world of neon style buttons, showcasing the impressive spectrum of CSS …




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Love affair with leather

Designer Sonal Verma tells us how leather craftsmanship is giving her a push into the world of fashion




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Creativity on Chanderi

Aneeth Arora tells MADHUR TANKHA how she has given the fabric a new meaning for her latest collection




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For the festive season, designers are working with artisans to create clothes with a conscience

As gifting and dressing up for the festive season begins, consumers are increasingly looking at sustainable, environment friendly choices



  • Life & Style

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From techno-inspired rave bags to pants that depict neurons, this Chennai-based gender neutral fashion label’s creations are conversation starters

Brimming with cut outs, panels, thread piping and embroidery, Biskit’s new collection explores the human mind



  • Life & Style

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