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iQOO Neo 7 Review

Read the in depth Review of iQOO Neo 7 Mobile Phones. Know detailed info about iQOO Neo 7 configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.




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iQOO Z7 Review

Read the in depth Review of iQOO Z7 Mobile Phones. Know detailed info about iQOO Z7 configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.




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iQOO Neo 7 Pro 5G Review

Read the in depth Review of iQOO Neo 7 Pro 5G Mobile Phones. Know detailed info about iQOO Neo 7 Pro 5G configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.




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iQOO Z7 Pro Review

Read the in depth Review of iQOO Z7 Pro Mobile Phones. Know detailed info about iQOO Z7 Pro configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.





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BoardSurfers: Training Insights: What’s New in the Allegro PCB Editor Basic Techniques Course

The Allegro PCB Editor Basic Techniques course provides all the essential training required to start working with Allegro® PCB Editor. The course covers all the design tasks, including padstack and symbol creation, logic import, constraints setup...(read more)




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2025 Hyundai Ioniq 5

What kind of car is the 2025 Hyundai Ioniq 5? What does it compare to? Hyundai’s Ioniq 5 is a small hatchback EV with value baseline pricing. Rivals include the VW ID.4, Tesla Model Y, and Ford Mustang Mach-E. Is the 2025 Hyundai Ioniq 5 a good car? Yes. This Hyundai is one of the better options in its segment, with peppy performance...




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2026 Cadillac Vistiq electric 3-row SUV revealed with $78,790 price tag

Cadillac Vistiq revealed as brand's “globally sized” electric three-row SUV Vistiq comes standard with 615 hp and 102 kwh Pricing starts at $78,790, including destination Cadillac's expansion of its electric vehicle lineup continues with the arrival of the 2026 Vistiq, a midsize SUV with third-row seats designed to fill the gap between...




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2026 Cadillac Vistiq targets 300 miles of range, costs $78,790

The Cadillac Vistiq will serve as the electric XT6 three-row SUV replacement Cadillac Vistiqs are expected to have about 300 miles of EPA-rated range The Vistiq will cost $78,790 when it arrives in 2025. Cadillac on Tuesday confirmed additional details of the Vistiq three-row electric SUV, which remains on track for a launch next year as a 2026...




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57+ unique gift ideas for Dad that are way better than a tie

Browse our favorite dad gift ideas for the holiday season. Try to think outside the gift card this year.




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My husband is my role model -Janet, etiquette consultant

Janet Temitope Adetu is a certified corporate etiquette and brand analyst as well as a professional image and international protocol consultant. The founder of JSK Etiquette Consortium, a thriving business etiquette, behavourial change and professional image enhancement firm, talks about her profession and how she juggles this with her marriage in this interview with QISMAT YINUS. Excerpts: What exactly do you do at JSK Etiquette Consortium? JSK Etiquette Consortium is a Corporate Etiquette, Professional Image and International Protocol Consultancy. We help corporate organisations leverage their human capital through personal and professional image projection, branding, impression management and leadership. Our objective […]




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Pacific Islands Conference of Leaders Issues Summit Communiqué

Pacific Islands Conference of Leaders Issues Summit Communiqué Pacific Islands Conference of Leaders Issues Summit Communiqué
ferrard Thu, 06/10/2021 - 21:59

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore




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Asian Development Blog: How to Build Deep and Liquid Capital Markets in Asia and the Pacific

Overcoming poor market depth and liquidity is crucial for Asia's capital markets to grow and remain attractive to investors. A coordinated approach addressing regulatory frameworks, market infrastructure, and risk management is essential for building resilient, diverse, and efficient markets.




iq

to write a paper critique

to write a paper critique




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Liquid crystals could improve quantum communication devices

Quantum light is key to futuristic quantum technologies, but researchers have been creating it in the same way for 60 years – now liquid crystals offer an easier way to produce it




iq

Jets of liquid bounce off hot surfaces without ever touching them

Droplets of fluid have been known to hover above a hot surface, but a new experiment suggests the same can happen to tiny jets of liquid too




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Ice might be ubiquitous, but we are still discovering things about it

Once seen as miraculous, these days ice is no longer extraordinary. But in a winter season when Antarctic sea ice hit a historic low, it is clear we should cherish it more, says Max Leonard




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In satire Rumours, diplomatic communiques collide with the end times

A stellar cast play leaders of G7 countries facing an existential crisis in Rumours, a smart film about communication, diplomatic nonsense and not coping, says Simon Ings




iq

Jets of liquid bounce off hot surfaces without ever touching them

Droplets of fluid have been known to hover above a hot surface, but a new experiment suggests the same can happen to tiny jets of liquid too




iq

Pot Use in Teen Years May Lower IQ, Study Shows

Title: Pot Use in Teen Years May Lower IQ, Study Shows
Category: Health News
Created: 8/28/2012 11:01:00 AM
Last Editorial Review: 8/28/2012 12:00:00 AM




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Weight-Loss Drug Belviq Is First to Show No Harm to Heart

Title: Weight-Loss Drug Belviq Is First to Show No Harm to Heart
Category: Health News
Created: 8/27/2018 12:00:00 AM
Last Editorial Review: 8/28/2018 12:00:00 AM




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Drinking at Home: Liquor Store Sales Rose During Pandemic

Title: Drinking at Home: Liquor Store Sales Rose During Pandemic
Category: Health News
Created: 8/24/2021 12:00:00 AM
Last Editorial Review: 8/24/2021 12:00:00 AM




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Qigong Meditation for Beginners: Techniques, Benefits, and More

Title: Qigong Meditation for Beginners: Techniques, Benefits, and More
Category: Health and Living
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/24/2022 12:00:00 AM




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Breathing techniques to reduce symptoms in people with serious respiratory illness: a systematic review

Background

In adults with serious respiratory illness, breathlessness is prevalent and associated with reduced health-related quality of life. The aim of this review was to assess the impact of breathing techniques on breathlessness in adults with serious respiratory illness.

Methods

Electronic databases were searched to identify randomised controlled trials testing breathing techniques (techniques that aim to alter the respiratory pattern, excluding respiratory muscle training) in people with serious respiratory illness. The primary outcome was breathlessness and secondary outcomes were health-related quality of life and adverse events. Two authors independently screened for inclusion, evaluated risk of bias and extracted data.

Results

73 randomised controlled trials were included with 5479 participants, most with COPD or asthma. Breathing exercises (pursed lip and/or diaphragmatic breathing) reduced breathlessness measured by the modified Medical Research Council scale compared to usual care (mean difference (MD) –0.40 points, 95% CI –0.70– –0.11, eight studies, n=323), although the effect did not exceed the minimal important difference. Yoga breathing also improved modified Medical Research Council score compared to usual care (MD –1.05 points, 95% CI –2.45–0.35, three studies, n=175). Breathing techniques consistently improved health-related quality of life in people with COPD and asthma on multiple health-related quality of life measures in comparison to usual care, with effects that generally exceeded the minimal important difference. No adverse events related to breathing techniques were reported.

Conclusion

Breathing techniques may improve breathlessness, and consistently improve health-related quality of life, in people with serious respiratory illness. These findings support the use of breathing exercises in the care of people with serious respiratory illness.




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Comparison of Needle Depth Techniques for the Posterior Superior Alveolar Block

Purpose The posterior superior alveolar (PSA) block injection is one of many techniques used to provide profound anesthesia for invasive dental procedures. This technique has a high success rate but is not without complication risks. The purpose of this study was to determine if pulpal anesthesia of the maxillary second molar could be achieved using a reduced needle depth of 10mm or 5mm compared to the traditional needle depth of 16mm.Methods Sixty participants were asked to participate in three sessions. Each session started with a pre neural response test, followed by one randomized needle depth PSA injection, and ending with a post neural response test. The neural response test consisted of two parts, a cold refrigerant and a dental probe, on the buccal and interproximal surface of the maxillary second molar. After receiving a positive neural response, each participant received a posterior superior alveolar block injection using a short (21mm), 27-gauge dental needle with a randomized needle penetration depth of 16mm, 10mm, or 5mm. A post neural response test consisting of the same two parts as the pre-test was conducted on the maxillary second molar to evaluate for profound anesthesia.Results Positive neural responses were obtained from 100% of the participants (n=167) during the pre-tests. Study results demonstrated an 85% success rate at the traditional 16mm needle depth and a 93% and 92% success rates for the reduced needle depths of 10mm and 5mm, respectively. Pulpal anesthesia of the maxillary second molar had been achieved at all three needle depths with no statistically significant difference in the rate of success. Furthermore, there were no adverse events observed.Conclusion The reduced needle depth technique showed promise in achieving desired results of pulpal anesthesia with a reduced risk for complications associated with the PSA block injection. Additional studies are recommended to achieve evidence-based support for this reduced needle depth technique.




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Investigations into the Concentrations and Metabolite Profiles of Doping Agents and Antidepressants in Human Seminal Fluid Using Liquid Chromatography-Mass Spectrometry [Articles]

Exogenous substances, including drugs and chemicals, can transfer into human seminal fluid and influence male fertility and reproduction. In addition, substances relevant in the context of sports drug testing programs, can be transferred into the urine of a female athlete (after unprotected sexual intercourse) and trigger a so-called adverse analytical finding. Here, the question arises as to whether it is possible to distinguish analytically between intentional doping offenses and unintentional contamination of urine by seminal fluid. To this end, 480 seminal fluids from nonathletes were analyzed to identify concentration ranges and metabolite profiles of therapeutic drugs that are also classified as doping agents. Therefore, a screening procedure was developed using liquid chromatography connected to a triple quadrupole mass spectrometer, and suspect samples (i.e., samples indicating the presence of relevant compounds) were further subjected to liquid chromatography-high-resolution accurate mass (tandem) mass spectrometry. The screening method yielded 90 findings (including aromatase inhibitors, selective estrogen receptor modulators, diuretics, stimulants, glucocorticoids, beta-blockers, antidepressants, and the nonapproved proliferator-activated receptor delta agonist GW1516) in a total of 81 samples, with 91% of these suspected cases being verified by the confirmation method. In addition to the intact drug, phase-I and -II metabolites were also occasionally observed in the seminal fluid. This study demonstrated that various drugs including those categorized as doping agents partition into seminal fluid. Monitoring substances and metabolites may contribute to a better understanding of the distribution and metabolism of exogenous substances in seminal fluid that may be responsible for the impairment of male fertility.

SIGNIFICANCE STATEMENT

This study demonstrates that doping agents as well as clinically relevant substances are transferred/eliminated into seminal fluid to a substantial extent and that knowledge about drug levels (and potential consequences for the male fertility and female exposure) is limited. The herein generated new dataset provides new insights into an important and yet little explored area of drug deposition and elimination, and hereby a basis for the assessment of contamination cases by seminal fluid in sports drug testing.




iq

Exogenous Pregnane X Receptor Does Not Undergo Liquid-Liquid Phase Separation in Nucleus under Cell-Based In Vitro Conditions [Special Section on New and Emerging Areas and Technologies in Drug Metabolism and Disposition, Part II]

Pregnane X receptor (PXR) belongs to the nuclear receptor superfamily that plays a crucial role in hepatic physiologic and pathologic conditions. Phase separation is a process in which biomacromolecules aggregate and condense into a dense phase as liquid condensates and coexist with a dilute phase, contributing to various cellular and biologic functions. Until now, whether PXR could undergo phase separation remains unclear. This study aimed to investigate whether PXR undergoes phase separation. Analysis of the intrinsically disordered regions (IDRs) using algorithm tools indicated a low propensity of PXR to undergo phase separation. Experimental assays such as hyperosmotic stress, agonist treatment, and optoDroplets assay demonstrated the absence of phase separation for PXR. OptoDroplets assay revealed the inability of the fusion protein of Cry2 with PXR to form condensates upon blue light stimulation. Moreover, phase separation of PXR did not occur even though the mRNA and protein expression levels of PXR target, cytochrome P450 3A4, changed after sorbitol treatment. In conclusion, for the first time, these findings suggested that exogenous PXR does not undergo phase separation following activation or under hyperosmotic stress in nucleus of cells.

SIGNIFICANCE STATEMENT

PXR plays a critical role in hepatic physiological and pathological processes. The present study clearly demonstrated that exogenous PXR does not undergo phase separation after activation by agonist or under hyperosmotic stress in nucleus. These findings may help understand PXR biology.




iq

Stent Retriever AssIsted Lysis Technique with Tirofiban: A Potential Bailout Alternative to Angioplasty and Stenting [CLINICAL PRACTICE]

BACKGROUND AND PURPOSE:

Angioplasty and stent placement have been described as a bailout technique in individuals with failed thrombectomy. We aimed to investigate Stent retriever AssIsted Lysis (SAIL) with tirofiban before angioplasty and stent placement.

MATERIALS AND METHODS:

Patients from 2 comprehensive stroke centers were reviewed (2020–2023). We included patients with failed thrombectomy and/or underlying intracranial stenosis who received SAIL with tirofiban before the intended angioplasty and stent placement. SAIL consisted of deploying a stent retriever through the occluding lesion to create a bypass channel and infuse 10 mL of tirofiban for 10 minutes either intra-arterially or IV. The stent retriever was re-sheathed before retrieval. The primary end points were successful reperfusion (expanded TICI 2b–3) and symptomatic intracerebral hemorrhage. Additional end points included 90-day mRS 0–2 and mortality.

RESULTS:

After a median of 3 (interquartile range, 2–4) passes, 44 patients received the SAIL bridging protocol with tirofiban, and later they were considered potential candidates for angioplasty and stent placement bailout (43.2%, intra-arterial SAIL). Post-SAIL successful reperfusion was obtained in 79.5%. A notable residual stenosis (>50%) after successful SAIL was observed in 45.7%. No significant differences were detected according to post-SAIL: successful reperfusion (intra-arterial SAIL, 80.0% versus IV-SAIL, 78.9%; P = .932), significant stenosis (33.3% versus 55.0%; P = .203), early symptomatic re-occlusion (0% versus 8.0%; P = .207), or symptomatic intracerebral hemorrhage (5.3% versus 8.0%; P = .721). Rescue angioplasty and stent placement were finally performed in 15 (34.1%) patients (intra-arterial SAIL 21.0% versus IV-SAIL 44%; P = .112). At 90 days, mRS 0–2 (intra-arterial SAIL 50.0% versus IV-SAIL 43.5%; P = .086) and mortality (26.3% versus 12.0%; P = .223) were also similar.

CONCLUSIONS:

In patients with stroke in which angioplasty and stent placement are considered, SAIL with tirofiban, either intra-arterial or IV, seems to safely induce sustained recanalization, offering a potential alternative to definitive angioplasty and stent placement.




iq

Optimal Endovascular Therapy Technique for Isolated Intracranial Atherothrombotic Stroke-Related Large-Vessel Occlusion in the Acute-to-Subacute Stage [CLINICAL PRACTICE]

BACKGROUND AND PURPOSE:

Reocclusion after treatment is a concern in endovascular therapy for isolated intracranial atherothrombotic stroke-related large-vessel occlusion (AT-LVO). However, the optimal endovascular therapy technique for AT-LVO has not yet been investigated. This study evaluated the optimal endovascular therapy technique for AT-LVO in a real-world setting.

MATERIALS AND METHODS:

We conducted a historical, multicenter registry study at 51 centers that enrolled patients with AT-LVO. We divided the patients into 3 groups based on the endovascular therapy technique: mechanical thrombectomy alone, percutaneous transluminal angioplasty (PTA), and stent deployment. Mechanical thrombectomy alone was classified into the mechanical thrombectomy-only group; PTA and mechanical thrombectomy–PTA, into the PTA group; and mechanical thrombectomy–stent deployment, mechanical thrombectomy–PTA–stent deployment, PTA–stent deployment, and stent deployment–only into the stent group. The primary outcome was incidence of reocclusion of the treated vessels within 90 days of endovascular therapy completion.

RESULTS:

We enrolled 770 patients and analyzed 509 patients. The rates in the mechanical thrombectomy-only, PTA, and stent deployment groups were 40.7%, 44.4%, and 14.9%, respectively. Incidence rate of residual stenosis >70% of final angiography was significantly higher in the mechanical thrombectomy-only group than in the PTA and stent deployment groups (mechanical thrombectomy-only versus PTA versus stent deployment: 34.5% versus 26.3% versus 13.2%, P = .002). Reocclusion rate was significantly lower in the PTA group than in the mechanical thrombectomy-only group (adjusted hazard ratio, 0.48; 95% CI, 0.29–0.80). Of the patients, 83.5% experienced reocclusion within 10 days after endovascular therapy. Alarmingly, a substantial subset (approximately 62.0%) of patients experienced reocclusion within 2 days of endovascular therapy. Incidence of mRS scores of 0–2 ninety days after endovascular therapy was not significantly different among the 3 groups. Incidences of symptomatic intracranial hemorrhage, any other intracranial hemorrhage, and death were not significantly different.

CONCLUSIONS:

Incidence rate of reocclusion was significantly lower in the PTA group than in the mechanical thrombectomy-only group. We found no meaningful difference in reocclusion rates between the stent deployment and mechanical thrombectomy-only groups. In Japan, glycoprotein IIb/IIIa inhibitors are not reimbursed. Therefore, PTA might be the preferred choice for AT-LVOs due to the higher reocclusion risk with mechanical thrombectomy-only. Reocclusion was likely to occur within 10 days, particularly within 2 days post-endovascular therapy.




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Des politiques pour mieux soutenir les chirurgiennes enceintes [Commentaire]




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Reaction lepreuse de type 1 chez un homme de 50 ans [Pratique]




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Listeriose durant la grossesse [Pratique]




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Nobel prize for physics goes to pair who invented key AI techniques

The 2024 Nobel prize in physics has gone to John Hopfield and Geoffrey Hinton for discoveries that enabled machine learning and are key to the development of artificial intelligence models like ChatGPT




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Rise of the superbaby? US startup offers genetic IQ screening for wealthy elite: report

U.S.-based startup company Heliospect Genomics reportedly is offering wealthy couples embryo screening for IQ and other traits at $50,000 for 100 embryos.



  • a9f4cec8-f174-58c5-8724-21636f21cd43
  • fnc
  • Fox News
  • fox-news/science/natural-science/genetics
  • fox-news/science
  • fox-news/health
  • fox-news/us
  • fox-news/lifestyle
  • fox-news/science
  • article

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15,800-Year-Old Engraved Plaquettes Shed Light on Paleolithic Fishing Techniques

Scientists from the Leibniz Zentrum für Archäologie and Durham University have examined a collection of 406 engraved schist plaquettes found at the Magdalenian site of Gönnersdorf in Germany.

The post 15,800-Year-Old Engraved Plaquettes Shed Light on Paleolithic Fishing Techniques appeared first on Sci.News: Breaking Science News.




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Maximising Online Visibility and SEO for Restaurants: Tips and Techniques

In the bustling world of the restaurant industry, standing out is more challenging than ever. With diners increasingly turning to the internet to discover their next meal, having a strong online presence is crucial. This guide will show you practical tips and techniques to maximise your restaurant’s online visibility and enhance your SEO efforts. By […]

The post Maximising Online Visibility and SEO for Restaurants: Tips and Techniques appeared first on Chart Attack.




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Cadillac reveals the 2026 Vistiq EV SUV

Cadillac is adding to its fleet of EVs with a new luxury SUV. The 2026 Cadillac Vistiq is a three-row, all-electric SUV that will hit showrooms and dealerships sometime next summer with a starting price of $78,790.

The Vistiq’s dual-motor, all-wheel drive system runs on a 102 kWh battery pack with a range of 300 miles that produces 615 horsepower and 650 pound-feet of torque. The Vistiq also supports vehicle-to-home (V2H) bidirectional charging capabilities: it can charge at home, and also deliver electricity to your house during a power outage. Using the features requires buying the GM Energy V2H bundle though.

The SUV’s design borrows aesthetically from other Cadillac EVs. Like the Lyriq, it has flush door handles, and features similar looking lights and side panels. It also matches the Lyriq’s 300 mile range. The “swept-back windshield” and “Black Crystal Shield grill” evoke the Escalade IQ.

Of course, the Vistiq's power and price are different from its Cadillac EV's. The new Cadillac EV SUV is less expensive than an Escalade IQ ($129,990) but more than a Lyriq ($58,595), and the Escalade IQ has a higher peak battery range at 450 miles.

The Vistiq comes with a 23-speaker AKG7 Studio Audio system with Dolby Atmos. The Android-powered infotainment system is baked into a 33-inch high resolution LED display. The Verge also reported that the new EV’s navigation system uses Google Maps and can run other apps from the Google Play Store.

Apple CarPlay and Android Auto won’t be available in Cadillac’s newest EV. General Motors is phasing out Apple CarPlay and Android Auto from its EVs and plans to go with Android Automotive. GM’s Executive Director of Digital Cockpit Experience Edward Kummer said in a Reuters interview that the carmaker didn’t want any features in its EVs “that are dependent on a person having a cellphone.”

This article originally appeared on Engadget at https://www.engadget.com/transportation/evs/cadillac-reveals-the-2026-vistiq-ev-suv-191557412.html?src=rss




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[EN IMAGES] Vol spectaculaire: un guichet automatique extirpé d’une caisse Desjardins en Mauricie

Des voleurs ont réussi à dérober un guichet automatique en le tirant à travers la devanture vitrée de l’immeuble à l’aide d’un camion.




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«Ce n’est pas vrai que je n’ai rien fait»: une ex-directrice de l'école Bedford avait sonné l’alarme à propos du climat toxique

Pour la première fois, une ex-directrice de l’école Bedford explique de vive voix avoir alerté plusieurs fois ses supérieurs quant au climat toxique.




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L’ancien premier ministre de la Colombie-Britannique John Horgan est décédé

L’ex-premier ministre de la Colombie-Britannique John Horgan est décédé à l’âge de 65 ans après une bataille contre le cancer.




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Procès pour triple meurtre à Brossard: incursion dans une scène de crime sanglante et chaotique pour le jury

Le jury au procès du père accusé d’avoir décimé sa famille a eu droit à une véritable incursion dans la scène de crime.




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Le film «Monsieur Aznavour» présenté à Montréal samedi: une première «symbolique» pour le réalisateur Grand Corps Malade

Gros succès en France, le drame biographique est présenté samedi au Festival Cinemania.




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Le stress chronique affaiblit le système immunitaire

Une étude rapporte que la perturbation de l’équilibre du microbiote intestinal par le stress dérègle la fonction des cellules immunitaires.





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US renewable diesel imports fall, spot liquidity stalls




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Circulation de l�information transatlantique: comment s�assurer que les investisseurs am�ricains ne voient pas d��crans vides - Trans-Atlantic Information Flow

Trans-Atlantic Information Flow






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Informe reciente resalta la necesidad de concentrarse más en que las familias planifiquen para estar preparadas - Waiting 30 Seconds Spanish

Waiting 30 Seconds Spanish




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As Fat Grafting Evolves, Aesthetic Plastic Surgeons Discover That Less Can Be More, It's Not Just For The Breasts And Buttocks, And Fat Doesn't Always Act Like Fat - Body Contouring with Fat, AKA Liquid Gold

Video 1 Preview Image Caption