1 Mexican Peso = 275.9169 Paraguayan Guarani

1 Brazilian Real = 1139.4501 Paraguayan Guarani

1 United Arab Emirates Dirham = 1778.2203 Paraguayan Guarani

1 Sri Lanka Rupee = 35.019 Paraguayan Guarani

1 Algerian Dinar = 50.8951 Paraguayan Guarani

1 Indonesian Rupiah = 0.4378 Paraguayan Guarani

1 Lithuanian Lita = 2212.0708 Paraguayan Guarani

1 Nigerian Naira = 16.7479 Paraguayan Guarani

1 Czech Republic Koruna = 259.8884 Paraguayan Guarani

1 Bolivian Boliviano = 947.2119 Paraguayan Guarani

1 Japanese Yen = 61.229 Paraguayan Guarani

A lack of guidance for some non-essential dental treatments is causing concern for hygienists and assistants as clinics reopen in Alberta during the COVID-19 pandemic.

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SOPEMI 2011EbookFragments_with_friendlyGreece_engl

The Indian realty sector and its current condition is going to have a profound impact on the country's economy. This is because of a large number of individuals and businesses depend on the sector as it alone contributes 7-8% to the

Hand hygiene is very crucial in controlling infections. The increasing severity of illnesses, multi-drug resistant pathogens and complexity of treatment methods are making basic preventions like hand hygiene essential in our day-to-day lives. This is because hand hygiene is very important

Jimmy Garoppolo's teammates are not here for slander of their quarterback.

The final supermoon of 2020 made an appearance in the night sky on Thursday night and stunned stargazers with its sheer size and brightness.The full moon will appear about six per cent larger than a typical full moon.

Officials inspect Jiribam Railway Station, school playground

The structure and function of dioxygenases in histone demethylation and DNA/RNA dimethylation are discussed.

MICAL is an oxidoreductase that participates in cytoskeleton reorganization via actin disassembly in the presence of NADPH. Although three MICALs (MICAL1, MICAL2 and MICAL3) have been identified in mammals, only the structure of mouse MICAL1 has been reported. Here, the first crystal structure of human MICAL3, which contains the flavin-containing monooxygenase (FMO) and calponin-homology (CH) domains, is reported. MICAL3 has an FAD/NADP-binding Rossmann-fold domain for mono­oxygenase activity like MICAL1. The FMO and CH domains of both MICAL3 and MICAL1 are highly similar in structure, but superimposition of the two structures shows a different relative position of the CH domain in the asymmetric unit. Based on kinetic analyses, the catalytic efficiency of MICAL3 dramatically increased on adding F-actin only when the CH domain was available. However, this did not occur when two residues, Glu213 and Arg530, were mutated in the FMO and CH domains, respectively. Overall, MICAL3 is structurally highly similar to MICAL1, which suggests that they may adopt the same catalytic mechanism, but the difference in the relative position of the CH domain produces a difference in F-actin substrate specificity.

A recent survey of the bottom-dwelling animals of the Chesapeake has revealed that communities of even these relatively hardy organisms are under stress. Many regions of the bay are becoming inhospitable to bottom-dwelling animals because of a lack of oxygen—a condition known as “hypoxia.”

The post Bottom-dwelling creatures in the Chesapeake Bay need more oxygen, study finds. appeared first on Smithsonian Insider.

Astronomers are confident the Cygnus X-1 system contains a black hole, and with these latest studies they have remarkably precise values of its mass, spin, and distance from Earth.

The post New details on birth of black hole Cygnus X-1 revealed by Chandra X-ray Observatory appeared first on Smithsonian Insider.

Deep observations with NASA's Chandra X-ray Observatory of Cygnus OB2 have been used to detect the X-ray emission from the hot outer atmospheres, or coronas, of young stars in the cluster and to probe how these great star factories form and evolve.

The post Cygnus OB2: Probing a nearby stellar cradle appeared first on Smithsonian Insider.

Size isn’t the only thing that’s small about the pygmy sloth―its population is too. But scientists at the Smithsonian say things may be looking up […]

The post Study reveals more Pygmy Sloths, But There Still Aren’t Many appeared first on Smithsonian Insider.

Higher acidity in coastal waters can make fish more sensitive to low oxygen, causing them to become debilitated and suffocate in water with oxygen levels […]

The post Acidification, Low Oxygen Can be Deadly Combination for Fish appeared first on Smithsonian Insider.

 The distant planet GJ 1132b intrigued astronomers when it was discovered last year. Located just 39 light-years from Earth, it might have an atmosphere despite […]

The post Venus-like Exoplanet Might Have Oxygen Atmosphere, But Not Life appeared first on Smithsonian Insider.

Bipasha Dey and Richa Rikhy

Cell shape morphogenesis from spherical to polygonal occurs in epithelial cell formation in metazoan embryogenesis. In syncytial Drosophila embryos, the plasma membrane incompletely surrounds each nucleus and is organized as a polygonal epithelial-like array. Each cortical syncytial division cycle shows circular to polygonal plasma membrane transition along with furrow extension between adjacent nuclei from interphase to metaphase. In this study, we assess the relative contribution of DE-cadherin and Myosin II at the furrow for polygonal shape transition. We show that polygonality initiates during each cortical syncytial division cycle when the furrow extends from 4.75 to 5.75 µm. Polygon plasma membrane organization correlates with increased junctional tension, increased DE-cadherin and decreased Myosin II mobility. DE-cadherin regulates furrow length and polygonality. Decreased Myosin II activity allows for polygonality to occur at a lower length than controls. Increased Myosin II activity leads to loss of lateral furrow formation and complete disruption of polygonal shape transition. Our studies show that DE-cadherin-Myosin II balance regulates an optimal lateral membrane length during each syncytial cycle for polygonal shape transition.

“When you can’t breathe, nothing else matters,” once a tagline of the American Lung Association, today it might easily describe what is happening in many […]

The post Gasping for air: nutrients, warming trigger ocean oxygen deficit appeared first on Smithsonian Insider.

Good morning. On behalf of the National Academies and my colleagues on the committee, I welcome those of you in the room as well as those listening to the live audio webcast.

The federal government should not rely on polygraph examinations for screening prospective or current employees to identify spies or other national-security risks because the test results are too inaccurate when used this way.

A new study provides recommendations to reduce the environmental impact of personal hygiene and cleaning products on the environment. Researchers undertook life-cycle assessments of products including detergents, soaps and toilet cleaners, and compared their environmental footprints looking at different types of environmental damage.

Hypoxia – low levels of dissolved oxygen – can cause genetically female fish to develop into males, new research has found. Hypoxia in aquatic environments is often the result of eutrophication, which is caused by pollution from human activities. The findings suggest that hypoxia could cause fish populations to collapse, with consequences for entire ecosystems.

Low oxygen levels (‘hypoxia’) are a pressing concern for marine and freshwater ecosystems worldwide, and this may deteriorate as ocean temperatures rise. Hypoxia causes stress in organisms, which can cause reproductive impairments that persist across generations — even the offspring that have never been exposed to hypoxia. Previous studies discovered that hypoxia can disrupt sex hormones, resulting in birth defects and affecting reproduction of male fish over several generations. This study shows how hypoxia can also affect female marine medaka (Oryzias melastigma) over multiple generations — and thus may pose a significant threat to the sustainability of natural fish populations worldwide.

Oxygen decline is occurring in many of the world’s oceans and has important consequences for marine ecosystems, but the causes are not fully understood. Aerosol pollutants may be partly responsible, according to a new study which modelled the effects of atmospheric pollution over the Pacific Ocean. The findings suggest that air pollution can exacerbate climate impacts on the ocean, even when the source is far away.

As a growing number of homeless people take to Los Angeles' subway system, officials consider installing mobile showers and bathrooms at certain stations.

The idea behind Toshiko Horiuchi MacAdam's lovely, loopy play structures was born when children started playing on the designer's crochet sculpture in an art ga

Here's a handy cheat sheet to help you keep the spacecraft straight.

Rutherford Seydel's Oxygen Project creates a sustainable Earth while creating financial sustainability for all. All it will take is a massive group action.

If a bird has zygodactyl feet, that means two toes point forward and two point back. This makes life easier for woodpeckers, owls, parrots and ospreys.

Artist and teacher Ruganzu Bruno Tusingwire wins the first 10K prize at TEDxQuatar with his innovative recycling idea that helps kids in need.