The cryptocurrency market is no stranger to the rise of meme coins, but one new project, FreeDum Fighters (DUM), is… Continue reading 2024 Bull Run Ignites as FreeDum Fighters Presale Hits the Market at Perfect Timing

The post 2024 Bull Run Ignites as FreeDum Fighters Presale Hits the Market at Perfect Timing appeared first on ReadWrite.

Paulen, R C; Rice, J M; Ross, M; Lian, O B. Geoconvention 2020 abstracts; 2020 p. 1-4
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20200034.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20200034.jpg" title="Geoconvention 2020 abstracts; 2020 p. 1-4" height="150" border="1" /></a>

Davis, W J; Sanborn-Barrie, M; Berman, R G; Pehrsson, S. Canadian Journal of Earth Sciences vol. 58, issue 4, 2021 p. 378-395, https://doi.org/10.1139/cjes-2020-0046
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20200302.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20200302.jpg" title="Canadian Journal of Earth Sciences vol. 58, issue 4, 2021 p. 378-395, https://doi.org/10.1139/cjes-2020-0046" height="150" border="1" /></a>

Neil, B J C; Tersmette, D B; Chacko, T; Heaman, L M; Kjarsgaard, B A; Martel, E; Creaser, R A; Pearson, D G; Stern, R A; Dufrane, S A; Luo, Y. Geology vol. 51, no. 6, 2023 p. 597-601, https://doi.org/10.1130/G51110.1
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20230012.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20230012.jpg" title="Geology vol. 51, no. 6, 2023 p. 597-601, https://doi.org/10.1130/G51110.1" height="150" border="1" /></a>

Two OMer's plan a trip out to eastern Turkey to share the gospel with the lost, as their plans keep changing along the way.

What time do you usually eat your dinner? Here's what this Harvard study reveals about the best time for dinner.

Fr. John talks about Luke 7, the raising of the widow's son, and how important it is to remember the timing of God.

In the end, your success or failure is a combination of what you control (your decision making) and what you don't (timing). Most people aren't really great at decision making. But that's something you can get better at. So let's move to the harder dynamic that we can't control – and that's timing. Everything in ... Read more

The post Premature Optimization is a Timing Mistake appeared first on Chris Lema.

Knowing the best times to buy or sell can be critical during the exiting of your business.

A Celestial Marketing Strategy: Execution of JayQ The Legend's galactic anthem "Back 2 Back"

How much does take-up timing for agricultural inputs depend on price? Evidence from an experiment in Nigeria

Insights into buying behavior.

The post How much does take-up timing for agricultural inputs depend on price? Evidence from an experiment in Nigeria appeared first on IFPRI.

The timing of the Red Sea attacks could not be worse for Democrats (Politico)

Senior research fellow Joseph Glauber is quoted in a Politico story about how the growing military conflict in a key trade corridor is threatening to unleash economic havoc on the global economy ahead of November. “If energy prices go up and remain high, you’d see food inflation persisting,” said Joe Glauber. He added that potential […]

The post The timing of the Red Sea attacks could not be worse for Democrats (Politico) appeared first on IFPRI.

The MSTR chart is a perfect example of the importance of market timing. The MSTR stock did nothing for almost two decades! Imagine investing in it early and waiting 20 years to get a return.

If you want to have conviction in your ideas, you need to know what moves your stocks and position for that change. In the book “The New Market Wizards”, Stanley Druckenmiller said this in response to the question of how he evaluates stocks:

“When I first started out, I did very thorough papers covering every aspect of a stock or industry. Before I could make the presentation to the stock selection committee, I first had to submit the paper to the research director."

"I particularly remember the time I gave him my paper on the banking industry. I felt very proud of my work. However, he read through it and said, This is useless. What makes the stock go up and down? That comment acted as a spur."

"Thereafter, I focused my analysis on seeking to identify the factors that were strongly correlated to a stock's price movement as opposed to looking at all the fundamentals. Frankly, even today, many analysts still don't know what makes their particular stocks go up and down.”

His number one advice? Do not invest in the present. The present does not move stock prices. Change moves them.

MicroStrategy is basically a Bitcoin play, so you just need to know where Bitcoin is going to trade MSTR stock. No valuation analysis needed.

The catalyst for the latest rally? Trump's victory.

This is why waiting for the right catalysts is paramount. Not only does it tell you WHEN to trade, but it also gives you an IMMEDIATE feedback on whether you are right or wrong. That helps with knowing when to bet more and when to get out to keep your drawdown low.

Disney World: Getting the new Tron roller coaster online is a matter of timing.

DSTR-DFSRP - The regulator's perspective on the right timing for inducing interoperability

Timing characteristics of an enhanced synchronous equipment slave clock

Timing and synchronization aspects in packet networks

Amyloid fibrils are polymeric structures originating from aggregation of misfolded proteins. In vivo, proteolysis may modulate amyloidogenesis and fibril stability. In light chain (AL) amyloidosis, fragmented light chains (LCs) are abundant components of amyloid deposits; however, site and timing of proteolysis are debated. Identification of the N and C termini of LC fragments is instrumental to understanding involved processes and enzymes. We investigated the N and C terminome of the LC proteoforms in fibrils extracted from the hearts of two AL cardiomyopathy patients, using a proteomic approach based on derivatization of N- and C-terminal residues, followed by mapping of fragmentation sites on the structures of native and fibrillar relevant LCs. We provide the first high-specificity map of proteolytic cleavages in natural AL amyloid. Proteolysis occurs both on the LC variable and constant domains, generating a complex fragmentation pattern. The structural analysis indicates extensive remodeling by multiple proteases, largely taking place on poorly folded regions of the fibril surfaces. This study adds novel important knowledge on amyloid LC processing: although our data do not exclude that proteolysis of native LC dimers may destabilize their structure and favor fibril formation, the data show that LC deposition largely precedes the proteolytic events documentable in mature AL fibrils.

Guo-qiang Bi
Dec 15, 1998; 18:10464-10472
Articles

David’s role on the Riverboat is to act as a homeless man. In reality, he is acting out a familiar life he used to lead.

I am working with innovus on a huge design. I found some cells are placed far away from both timing start points and timing end points. I suspect some other timing paths may be near-critical that results in this sub-optimal cell placement; or innovus has to place the cell far away due to congestion of placement or routing.

Is there a way to see why innovus places/moves the cell during place_opt_design or ccopt_design?

Also, is there a way to highlight all timing start points or timing end points that go through a cell? There may be thousands of timing paths through this cell. I tried using report_timing and timing debugger but it is very painful to click the highlight box and highlight the timing paths one by one.

Thank you for your help!

We are currently setting up the Tempus flow and have ran into some mismatched data regarding ECO and timing reports. I generated a timing report before running ECO and saw six total setup violations. When running opt_signoff -setup, the initial setup summary that was printed in the shell only showed one violation. I can see that violation from the initial setup summary in my pre-ECO timing report and it is not the worst path. Upon further investigation, I forced the tool to try to fix setup on one of the other five violations from the timing report using the opt_signoff_select_setup_endpoints attribute and the tool said that the endpoint had positive slack and would be ignored.

Has anyone experienced something like this before?

Hansen was comfortably reelected to the state Senate last week, winning 84% of the vote.

Title: Young Driver's Gender May Play Role in Timing, Type of Crash
Category: Health News
Created: 8/28/2014 12:36:00 PM
Last Editorial Review: 8/29/2014 12:00:00 AM

Title: Shorter Menstrual Cycles May Affect Timing of Menopause
Category: Health News
Created: 8/25/2022 12:00:00 AM
Last Editorial Review: 8/25/2022 12:00:00 AM

Traditionally, three days following fertilization, embryos are placed into the uterus during IVF treatment. It is now also feasible to do this after five

Limiting solar power usage at night may deter investors from pursuing new projects, say experts

Matt Maiocco explains why the timing was perfect for 49ers cornerback Deommodore Lenoir and San Francisco to finalize a contract extension now.

National Bureau of Economic Research

Passengers also say some buses leave earlier than scheduled or don’t pass certain rural areas, leading to schoolchildren not being able to board on time

The Japanese conglomerate plans to spend up to $4.8 billion to purchase as much as 7% of its own shares.

The post SoftBank’s share buyback plan is all about getting the timing right appeared first on DealStreetAsia.

Prevention of aberrant cutaneous wound repair and appropriate regeneration of an intact and functional integument require the coordinated timing of fibroblast and keratinocyte migration. Here, we identified a mechanism whereby opposing cell-specific motogenic functions of a multifunctional intracellular and extracellular protein, the receptor for hyaluronan-mediated motility (RHAMM), coordinates fibroblast and keratinocyte migration speed and ensures appropriate timing of excisional wound closure. We found that, unlike in WT mice, in Rhamm-null mice, keratinocyte migration initiates prematurely in the excisional wounds, resulting in wounds that have re-surfaced before the formation of normal granulation tissue, leading to a defective epidermal architecture. We also noted aberrant keratinocyte and fibroblast migration in the Rhamm-null mice, indicating that RHAMM suppresses keratinocyte motility but increases fibroblast motility. This cell context–dependent effect resulted from cell-specific regulation of extracellular signal-regulated kinase 1/2 (ERK1/2) activation and expression of a RHAMM target gene encoding matrix metalloprotease 9 (MMP-9). In fibroblasts, RHAMM promoted ERK1/2 activation and MMP-9 expression, whereas in keratinocytes, RHAMM suppressed these activities. In keratinocytes, loss of RHAMM function or expression promoted epidermal growth factor receptor–regulated MMP-9 expression via ERK1/2, which resulted in cleavage of the ectodomain of the RHAMM partner protein CD44 and thereby increased keratinocyte motility. These results identify RHAMM as a key factor that integrates the timing of wound repair by controlling cell migration.

Two OMer's plan a trip out to eastern Turkey to share the gospel with the lost, as their plans keep changing along the way.

Best Practices for Optimization What should be my considerations while preparing data? Libraries, HDL, Constraints... A good result from a synthesis tool depends greatly on the input data. An old saying "garbage in garbage out" is also true for...(read more)

The design and physical implementation engineers involved in early to late stage synthesis require a flow that helps them investigate timing using a structured and physically aware approach. Cadence Encounter® RTL Compiler (RC) Timing Analyzer was developed...(read more)

Marc Maron's new Netflix special is titled "End Times Fun."; Credit: Adam Rose / Netflix

Read the full article at KPCC

Wildfires in the Mediterranean region are a significant threat to human life and the natural environment and cause considerable economic damages. Recent research from Italy suggests that different types of land cover influence the timing of wildfires throughout the year and this knowledge can be used to improve fire risk assessment and prevention strategies.

The social, political, technological and geophysical factors that affect the control of climate change have been assessed in a recent study. The results suggest that political factors, in terms of delaying the implementation of mitigation strategies, have the biggest effect on limiting global warming to below 2C.

Timing matters: Flowers bloom, insects emerge, birds migrate, and planting and hunting seasons are carefully coordinated times in order to take advantage of wha

North Carolina, Virginia and South Carolina may have something to gain when it comes to offshore drilling, but the events of 2010 remind us that they also have