synthesis Synthesis, crystal structure and Hirshfeld surface analysis of N-(4-methoxyphenyl)picolinamide By journals.iucr.org Published On :: 2024-11-14 The synthesis, crystal structure, and Hirshfeld surface analysis of N-(4-methoxyphenyl)picolinamide (MPPA), C13H12N2O2, are presented. MPPA crystallizes in the monoclinic space group P21/n, with a single molecule in the asymmetric unit. Structural analysis reveals that all non-hydrogen atoms are nearly coplanar, and the molecule exhibits two intramolecular hydrogen bonds that stabilize its conformation. Supramolecular features include significant intermolecular interactions, primarily C—H...π and various hydrogen bonds, contributing to the overall crystal cohesion, as confirmed by energy framework calculations yielding a total interaction energy of −138.3 kJ mol−1. Hirshfeld surface analysis indicates that H...H interactions dominate, followed by C...H and O...H interactions, highlighting the role of van der Waals forces and hydrogen bonding in crystal packing. Full Article text
synthesis Modular synthesis: the ultimate beginner's guide By www.musicradar.com Published On :: 2024-11-14T07:22:42+00:00 A look into the wonderfully complex world of modular Full Article
synthesis C–H activation-enabled synthesis of a piperazine-embedded azadibenzo[a,g]corannulene analogue By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00415A, Research ArticleLin Huang, Mengyu Qiu, Zhihao Chang, Duncan L. Browne, Jianhui HuangThe first example of an azadibenzo[a,g]corannulene analogue with an embedded piperazine ring on the flank of its polycyclic skeleton is reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of 10B-enriched 2,1-borazaronaphthalenes from o-aminostyrenes and 10BF3 By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00176A, Research ArticleWeihua Qiu, Jide Zhu, Rencai Tao, Kai Yang, Qiuling SongHerein we present a practical approach for preparing 10B-enriched 2,1-borazaronaphthalenes from o-aminostyrenes and 10BF3 (the primary source of boron-10) in the presence of chlorosilane.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of multisubstituted carbazol-4-amines from tetrahydrocarbazol-4-one oximes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00386A, Research ArticleJiahua Wang, Dandan Gao, Aanuoluwapo O. Oyejobi, Na Ji, Xiang-Ying Tang, Long WangA sequential synthetic method toward 1,3-disubstituted carbazol-4-amines is reported and an interesting C–S metathesis process is disclosed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis A Pd(II)-catalyzed denitrative alkyne annulation reaction for the synthesis of cyclopenta[b]chromanes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00344F, Research ArticlePratiksha Bhorali, Deep J. Kalita, Babulal Das, Sanjib GogoiThe first denitrative Pd(II)-catalyzed alkyne annulation reaction is reported for the synthesis of cyclopenta[b]chromanes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis DBU-catalyzed substitution-controlled synthesis of oxa[3.3.1] bridged ring and naphthylamine derivatives By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00012A, Research ArticleShiyu Xu, Zhihui Sun, Pengyutian Liu, Yuanlin Wei, Fan Sun, Man Zhao, Ying Wang, Ming Zhang, Guofeng Li, Hong LiangA switchable cascade cyclization reaction of ortho-alkynyl arylketones with amines has been developed, where the different reaction pathways are controlled by the substituent on the α-carbon of in-situ-generated ortho-alkynyl arylaldimines.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Modular synthesis of C2-symmetric nitrogen-containing polyaromatics via visible light-enabled reductive aza-6π electrocyclization By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00140K, Research ArticleQun-Liang Zhang, Qing-Tian Fan, Yirong Zhou, Jingli Zhang, Fang-Lin ZhangHere, an unprecedented one-step modular construction of C2-symmetric N-PACs through reduction/aza-6π electrocyclization was reported and the resultant C2-symmetric N-PAC could be converted into a powerful organic photocatalyst.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Chiral guanidine catalyzed cyclization reactions of 1,3-enynes for lactone synthesis: switchable H-bond catalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00374H, Research ArticleYongyan Zhang, Lichao Ning, Tianxin Zhu, Zheng Xie, Shunxi Dong, Xiaoming Feng, Xiaohua LiuCyclization and 1,4-conjugate addition/cyclization between 2-activated 1,3-enynes and azlactones were achieved with chiral guanidine-amides for enol-type activation to yield a range of δ-lactone derivatives.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Sustainable synthesis of long-acting local anesthetics ropivacaine and levobupivacaine under batch and continuous flow via asymmetric hydrogenation By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00072B, Research ArticleZhi Yang, Hanlin Chen, Linxi Wan, Xinyi Feng, Lingshuang Ma, Pei Tang, Fen-Er ChenA sustainable synthesis method was developed for long-acting local anesthetics, ropivacaine and levobupivacaine, using both batch and continuous flow processes via asymmetric hydrogenation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of a helical boron-doped PAH by post-functionalization of 3,9-diboraperylene By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00421C, Research ArticleCarina Mützel, Kazutaka Shoyama, Ana-Maria Krause, Frank WürthnerA doubly helical boron-doped polycyclic aromatic hydrocarbon was synthesized, which showed a low LUMO level, a high absorption coefficient and fluorescence (ΦF = 0.73), combined with a one-dimensional π–π stacking interaction in the solid state.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Regio- and stereo-selective synthesis of β-phenylthio enamides via intramolecular 1,2-thiol migration By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D3QO02078A, Research ArticleYunqing Zhuang, Jin Zhang, Kai Yang, Gehua Bi, Xin Huang, Weimin ZhangAn efficient and novel method for the direct synthesis of β-phenylthio enamides via intramolecular 1,2-thiol migration has been developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Enantioselective synthesis of 8-membered lactone derivatives via organocatalytic cascade reactions By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00148F, Research ArticleDong-Sheng Ji, Rui Zhang, Xu-Yan Han, Hai-Long Chai, Yucheng Gu, Xiu-Qin Hu, Peng-Fei XuThe challenging 8-membered lactone derivatives bearing two vicinal chiral stereocenters were synthesized via a cascade reaction mediated by the chiral squaramide.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Stereodivergent synthesis of chiral spiropyrazolones through Pd-catalyzed asymmetric sequential hydroalkylation of 1,3-enynes: unusual solvent effects on the enantioselectivity By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00358F, Research ArticleShan Wang, Long Li, Yifei Zheng, Luqing Li, Yingcheng Wang, Fangzhi Peng, Zhihui ShaoChiral spiropyrazolones were constructed through Pd-catalyzed asymmetric sequential hydroalkylation of 1,3-enynes. Four stereoisomers could be obtained through substrate control and chiral ligand control.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Electrochemically dehydrogenative C(sp2)–H/S–H cross-coupling: efficient synthesis of ortho-aminophenyl thioglycoside derivatives By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00171K, Research ArticleLi-Yan Hu, Li Zhu, Shen-Yuan Zhang, Yu-Xin Guo, Yuan Li, Jie Zhu, Lei WuA method has been reported for synthesizing aryl thioglycosides through direct electrocatalytic dehydrogenative C(sp2)–H/S–H cross-coupling.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Blue light-mediated carbene transfer reaction of thioesters with diazoesters: efficient synthesis of tetrasubstituted Z-enol esters By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00265B, Research ArticleShuncheng Wang, Hua Zhang, Jin Yang, Dongfang Zhang, Xin-Ping HuiAn efficient metal-free, blue light-mediated carbene transfer reaction of thioesters with diazoesters has been achieved. This protocol produced tetrasubstituted Z-enol esters containing arylsulfur groups in good yields under mild conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Visible-light-mediated catalyst-free synthesis of trifluoromethyl(spiro)-epoxides bearing contiguous quaternary centers By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00184B, Research ArticleJingchuan Lin, Yu Zhang, Jinxin Wang, Xinyu Han, Shenglan Zhu, Tong Li, Yanping Zhu, Wei-Dong ZhangHerein, we describe a non-covalent complex-mediated epoxidation strategy that can yield highly selective central spiro-epoxides by irradiation with visible light without the need for catalyst addition.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of benzothiophenes via sulfonium-[3,3]-rearrangement of aryl sulfoxides with allenenitriles By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2208-2214DOI: 10.1039/D4QO00121D, Research ArticleLei Zhang, Kun Wan, Huanhuan Wang, Mengyao Wang, Ao Cui, Xin Huang, Bo PengA facile synthesis of benzothiophenes from readily available aryl sulfoxides and allenenitriles has been established through sulfonium-rearrangement triggered cyclization.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis A formal (3 + 2) annulation–Cannizzaro cascade of bifunctional peroxides for the synthesis of dihydrofurans By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2215-2219DOI: 10.1039/D4QO00215F, Research ArticleYiwei Chen, Min Gao, Qianlan Xu, Jiumeng Zhang, Lin HuTunable tandem processes of bifunctional peroxides allow the divergent construction of functionalized dihydrofurans and epoxides by simply changing the basic conditions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of enantiopure 1,2,3-triazolylidene-type mesoionic carbene (MIC) conjugate acids featuring a rigid bicyclic scaffold By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2178-2181DOI: 10.1039/D4QO00269E, Research ArticleVojtěch Dočekal, Mohand Melaimi, Simona Petrželová, Jan Veselý, Xiaoyu Yan, Guy BertrandChiral NHCs have found numerous applications as ligands for transition metals and in their own right for asymmetric catalysis. We report a synthetic route from L-malic acid to enantiopure 1,2,3-triazoliums with the chiral center in a fused ring.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Selective photochemical synthesis of primary arylamines and symmetric diarylamines via amination of aryl bromides using Ni(NH3)6Cl2 as a nitrogen source and catalyst By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2313-2318DOI: 10.1039/D4QO00116H, Research ArticleZhehui Xu, Jianyang Dong, Geyang Song, Fuqiang Kong, Gang Li, Dong XueThe selective synthesis of primary arylamines and diarylamines via coupling reactions with ammonia as a nitrogen source is still challenging.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Prins cyclization of 1,3-dioxinone: synthesis of 11-epi-badkhysin By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,2332-2338DOI: 10.1039/D4QO00162A, Research ArticleXiaoliang Xu, Ping Hua, Yiren Xu, Baoqing He, Jingfeng Zhao, Liang Li, Wen Chen, Hongbin ZhangThe asymmetric synthesis of highly functional 11-epi-badkhysin has been accomplished using a structure-unit based approach.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Concise synthesis of succinimide-fused densely 1,3-cyclohexadienes via Co-catalyzed [2+2+2] cycloaddition of 1,6-diynes and maleimides By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00435C, Research ArticleJinhui Cai, Kaili Cen, Ziyi Zhai, Yuan Liu, Jiahao Wei, Mixia Ouyang, Guojun He, Shuyu Huang, Feng ZhaoHerein, we report a new route towards succinimide-fused densely 1,3-cyclohexadienes through the reaction of 1,6-diynes with electron-deficient alkenes under cobalt catalysis. This method shown high efficiency, wide substrate scope, good...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Development of a photoenzymatic one-pot hybrid system for the direct synthesis of 3,3-disubstituted indole-2-ketones from N-methyl indoles By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00371C, Research ArticleYao Yao, Yuan Yu, Ming-Liang Shi, Xin-Yue Fan, Ru-De Lin, Kun Li, Wen-Dian Li, Fei-Yan Tao, Na WangThe effective combination of photocatalysis and enzyme catalysis has been widely utilized for the synthesis of high-value-added products.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Efficient Synthesis of Benzophosphole Oxides by Ag-Promoted Radical Cycloisomerization By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00552J, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Liyao Ma, Sonia Mallet-Ladeira, Julien MONOT, Blanca Maria MARTIN VACA, Didier BourissouCycloisomerization reactions involving C–P bond formation have been overlooked to prepare P-heterocycles. We discovered here a simple, efficient and versatile route to benzophosphole oxides by reacting ortho-alkynyl secondary phosphine oxides...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of oxindole fused 1,3-oxazepanes via hydride transfer initiated ring expansion of pyrrolidine By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO00474D, Research ArticlePeng He, Zongkang Wang, Qiongwen Kang, Nana Fei, Chengyu Wang, Yanzhong LiAn efficient B(C6F5)3 catalyzed protocol for the synthesis of oxindole fused 1,3-oxazepanes from pyrrolidine substituted aryl alkynones has been developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis NHC-Catalyzed Stereoselective Synthesis of Spirooxindole Lactones by in situ Generated Oxindole-embedded o-Quinone Methides and Aldehydes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO00347K, Research ArticleZhengqiang Cao, Fang Hu, Yunpeng Chu, Jiaxue Pei, Xin-Ping HuiA novel N-heterocyclic carbene-catalyzed asymmetric [4 + 2] annulation of in situ generated oxindole-embedded o-quinone methides with aldehydes has been developed for the assembly of complicated spirooxindoles. The methodology provides...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of a pyridine-based covalent organic framework as an anode material for lithium-ion batteries By pubs.rsc.org Published On :: J. Mater. Chem. A, 2024, Advance ArticleDOI: 10.1039/D4TA00892H, PaperShixi Zhong, He Zhao, Yingming Ji, Xiuhua Li, Ting Shu, Zhiming Cui, Shijun LiaoCovalent organic framework (COF) materials with redox activity have emerged as promising electrode materials for lithium-ion batteries.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis A bioinspired sulfur-surrounded iron catalyst for ammonia synthesis By pubs.rsc.org Published On :: J. Mater. Chem. A, 2024, Advance ArticleDOI: 10.1039/D4TA00710G, PaperNa Zhang, Yubing Si, Qiang Fu, Xing ChenA nitrogenase-inspired inorganic compound consisting of iron (Fe) and molybdenum disulfide (MoS2) is designed with a promising capability of N2 fixation using first principles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Co–Co2C catalysts supported on carbon-coated ordered mesoporous silica with promoted CO insertion and C–C coupling for higher alcohol synthesis from syngas By pubs.rsc.org Published On :: J. Mater. Chem. A, 2024, Advance ArticleDOI: 10.1039/D4TA01179A, PaperZhuoshi Li, Siqi Fan, Zhuang Zeng, Shaoxia Guo, Xiaofeng Pei, Shouying Huang, Yong Wang, Yue Wang, Xinbin MaCo–Co2C catalysts supported on carbon-coated ordered mesoporous silica showed superior performance for HAS than catalysts with uncoated and amorphous supports.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of highly condensed phospholes by Lewis acid-assisted dehydrogenative Mallory reaction under visible light irradiation By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC05657D, Edge Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ikki Kamiyoshi, Yuki Kojima, Shibo Xu, Kosuke Yasui, Yuji Nishii, Koji HiranoA photo-promoted oxidative cyclization, that is, Mallory reaction of 2,3-diarylbenzophopholes has been developed. With an assistance of Bi(OTf)3 Lewis acid, the reaction proceeds smoothly under visible light irradiation even without...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3759-3777DOI: 10.1039/D4MD00498A, Research ArticleLucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. EnrizA diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3778-3794DOI: 10.1039/D4MD00281D, Research ArticleCarolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. PilliA novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3800-3816DOI: 10.1039/D4MD00585F, Research ArticleMarwa Abdel-Motaal, Dalal Ali Aldakhili, Ayman B. Farag, Ayman Abo Elmaaty, Marwa Sharaky, Nadia A. Mohamed, Saad Shaaban, Abdullah Yahya Abdullah Alzahrani, Ahmed A. Al-KarmalawyNovel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3880-3888DOI: 10.1039/D4MD00414K, Research ArticlePhuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. VoNovel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3862-3879DOI: 10.1039/D4MD00313F, Research ArticleDaniele Pala, David Clark, Christine Edwards, Elisa Pasqua, Laura Tigli, Barbara Pioselli, Piotr Malysa, Fabrizio Facchinetti, Fabio Rancati, Alessandro AccettaThis study reports a novel, potent and selective series of ROCK inhibitors based on 8-(azaindolyl)-benzoazepinones identified through a core-hopping strategy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3912-3912DOI: 10.1039/D4MD90040E, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex JosephThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABAA receptors By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36352-36369DOI: 10.1039/D4RA07074G, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Mingxing Qian, Yuanjian Xu, Hong-Jin Shu, Zi-Wei Chen, Lei Wang, Charles F. Zorumski, Alex S. Evers, Steven Mennerick, Douglas F. CoveyPhotoaffinity labels (PALs) for sulfated steroid binding sites on GABAA and NMDA receptors. The PALs have varying profiles of positive and negative modulatory (PAM and NAM) actions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of MOF-supported Pt catalyst with high electrochemical oxidation activity for methanol oxidation By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36370-36377DOI: 10.1039/D4RA06393G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Merve Akin, Hatice Kars, Muhammed Bekmezci, Aysenur Aygun, Mert Gul, Guray Kaya, Fatih SenIn this study, Pt and Pt@Ti-MOF NPs catalysts were synthesized by chemical reduction method. Ti-MOF structure was synthesized using the solvothermal method, and the effect of Ti-MOF on methanol oxidation was investigated.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Northern Cordillera geology: a synthesis of research from the Geo-mapping for Energy and Minerals program, British Columbia and Yukon By geoscan.nrcan.gc.ca Published On :: Thu, 25 Nov 2021 00:00:00 EDT Ryan, J J (ed.); Zagorevski, A (ed.). Geological Survey of Canada, Bulletin 610, 2021, 176 pages, https://doi.org/10.4095/326050<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326050.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326050.jpg" title="Geological Survey of Canada, Bulletin 610, 2021, 176 pages, https://doi.org/10.4095/326050" height="150" border="1" /></a> Full Article
synthesis Geophysical contributions to a synthesis of western Churchill geology and metallogeny By geoscan.nrcan.gc.ca Published On :: Tue, 20 Dec 2022 00:00:00 EDT Re-release; Tschirhart, V; Pehrsson, S; Wodicka, N; Percival, J A; Jefferson, C W; Peterson, T; Berman, R G. Geological Survey of Canada, Preprint 3, 2022, 47 pages, https://doi.org/10.4095/330639<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_330639.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_330639.jpg" title="Geological Survey of Canada, Preprint 3, 2022, 47 pages, https://doi.org/10.4095/330639" height="150" border="1" /></a> Full Article
synthesis Hudson Bay, Hudson Strait, Moose River, and Foxe basins: synthesis of Geo-mapping for Energy and Minerals program activities from 2008 to 2018 By geoscan.nrcan.gc.ca Published On :: Thu, 14 Sep 2023 00:00:00 EDT Re-release; Lavoie, D; Pinet, N; Zhang, S; Reyes, J; Jiang, C; Ardakani, O H; Savard, M M; Dhillon, R S; Chen, Z; Dietrich, J R; Hu, K; Craven, J A; Roberts, B; Duchesne, M J; Brake, V I; Huot-Vézina, G; Galloway, J M; McCracken, A D; Asselin, E; Decker, V; Beauchemin, M; Nicolas, M P B; Armstrong, D K; Hahn, K E. Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 37-76, https://doi.org/10.4095/326090<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326090.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326090.jpg" title="Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 37-76, https://doi.org/10.4095/326090" height="150" border="1" /></a> Full Article
synthesis Stratigraphy of the Labrador margin: a synthesis and new perspectives By geoscan.nrcan.gc.ca Published On :: Mon, 15 Aug 2022 00:00:00 EDT Dafoe, L T; Dickie, K; Williams, G L; McCartney, T. Geological synthesis of Baffin Island (Nunavut) and the Labrador-Baffin Seaway; by Dafoe, L T (ed.); Bingham-Koslowski, N (ed.); Geological Survey of Canada, Bulletin 608, 2022 p. 137-180, https://doi.org/10.4095/321829<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_321829.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_321829.jpg" title="Geological synthesis of Baffin Island (Nunavut) and the Labrador-Baffin Seaway; by Dafoe, L T (ed.); Bingham-Koslowski, N (ed.); Geological Survey of Canada, Bulletin 608, 2022 p. 137-180, https://doi.org/10.4095/321829" height="150" border="1" /></a> Full Article
synthesis Geological synthesis of Baffin Island (Nunavut) and the Labrador-Baffin Seaway By geoscan.nrcan.gc.ca Published On :: Mon, 15 Aug 2022 00:00:00 EDT Dafoe, L T (ed.); Bingham-Koslowski, N (ed.). Geological Survey of Canada, Bulletin 608, 2022, 432 pages, https://doi.org/10.4095/314542<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_314542.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_314542.jpg" title="Geological Survey of Canada, Bulletin 608, 2022, 432 pages, https://doi.org/10.4095/314542" height="150" border="1" /></a> Full Article
synthesis Thermochronological history of the northern Canadian Shield: a synthesis By geoscan.nrcan.gc.ca Published On :: Tue, 27 Feb 2024 00:00:00 EDT Kellett, D; Pehrsson, S; Skipton, D; Regis, D; Camacho, A; Schneider, D; Berman, R. Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 411-415, https://doi.org/10.4095/332507<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332507.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332507.jpg" title="Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 411-415, https://doi.org/10.4095/332507" height="150" border="1" /></a> Full Article
synthesis Geophysical contributions to a synthesis of western Churchill geology and metallogeny, Northwest Territories, Nunavut, and Saskatchewan By geoscan.nrcan.gc.ca Published On :: Tue, 27 Feb 2024 00:00:00 EDT Tschirhart, V; Pehrsson, S; Wodicka, N; Percival, J; Jefferson, C; Peterson, T; Berman, R. Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 295-325, https://doi.org/10.4095/332502<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332502.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332502.jpg" title="Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 295-325, https://doi.org/10.4095/332502" height="150" border="1" /></a> Full Article
synthesis New crustal subdivision and architecture of the south Rae Craton, Northwest Territories: a synthesis By geoscan.nrcan.gc.ca Published On :: Tue, 27 Feb 2024 00:00:00 EDT Pehrsson, S J. Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 283-287, https://doi.org/10.4095/332500<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332500.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332500.jpg" title="Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 283-287, https://doi.org/10.4095/332500" height="150" border="1" /></a> Full Article
synthesis Balancing Act: Nitrogen and Potassium Key to Boosting Apple Photosynthesis By www.newswise.com Published On :: Tue, 12 Nov 2024 10:35:15 EST Nitrogen and potassium are fundamental nutrients for plant growth, but imbalances frequently disrupt agricultural systems. In apple orchards, low potassium can severely limit carbon and nitrogen metabolism, impairing photosynthesis and yield. Potassium availability is often reduced by environmental factors such as soil leaching, while nitrogen is frequently over-applied due to its affordability and yield-enhancing effects. Given these challenges, optimizing nitrogen and potassium levels in apple trees warrants further research to counter the negative impact of nutrient imbalances on plant health and productivity. Full Article
synthesis Synthesis of vanillin via oxidation of kenaf stalks in the presence of CeO2: tuning the catalytic behaviour of CeO2 via nanostructure morphology By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36327-36339DOI: 10.1039/D4RA05833J, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Anita Ramli, Nur Akila Syakida Idayu Khairul Anuar, Normawati Mohamad Yunus, Alina Rahayu MohamedA different form of CeO2 nanostructures gives a prevalence of specific crystalline facets which display different reactivity in various catalytic processes. By adapting the shape and size, certain crystal clear facets can be exposed, leading to different structural and redox properties.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Correction: Design, synthesis, pharmacological evaluation, and in silico studies of the activity of novel spiro pyrrolo[3,4-d]pyrimidine derivatives By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36351-36351DOI: 10.1039/D4RA90128B, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Abdullah Y. A. Alzahrani, Wesam S. Shehab, Asmaa H. Amer, Mohamed G. Assy, Samar M. Mouneir, Maged Abdelaziz, Atef M. Abdel HamidThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
