science and technology Blood: Underappreciated Resource in the Health/Disease? By thenextelement.wordpress.com Published On :: Tue, 05 May 2015 22:48:50 +0000 Alternative title: Pitching a VC on Disruption of Blood Testing You may have seen some recent editorials about the necessary frequency of blood tests for healthy individuals, many of them prompted by a series of tweets from Mark Cuban: Although there are certainly potential dangers in expecting any and all test results to be immediatelyRead More Full Article Uncategorized biotech biotechnology blood cancer drug development immunooncology labcorp oncology theranos
science and technology None Better than One? (A Brief Note on VC in Smaller Hubs) By thenextelement.wordpress.com Published On :: Wed, 20 May 2015 00:58:24 +0000 Biotech venture funding metrics continue at historic highs, highlighting that the robust financing environment in the public markets continues to fuel the private markets as well. – Bruce Booth, partner Atlas Venture in Data Snapshot: Venture-Backed Biotech Financing Riding High, April 2015 Here in Madison, Wisconsin, you might not know that was true if youRead More Full Article Uncategorized angel investors biotech biotechnology VC venture capital Wisconsin
science and technology The Terrible, Horrible, No Good, Very Bad Pharma Day* By thenextelement.wordpress.com Published On :: Tue, 29 Sep 2015 12:34:47 +0000 A challenge You are passionate about providing an intervention (drug or device) to a group of patients who can’t access the current options due to availability or pricing. You could could go the philanthropic route to pay for the interventions. You could work towards regulation to apply downward pressure on pricing. No matter what, you have toRead More Full Article Uncategorized biotech biotechnology drug development drug pricing drug shortage patient advocacy pharma pharmaceutical
science and technology Day Three Notes – JP Morgan Healthcare Conference, San Francisco By feedproxy.google.com Published On :: Fri, 15 Jan 2016 18:12:24 +0000 Yesterday’s conference sessions surfaced interesting questions and approaches regarding the post-acute sector, bundled payment, emergency medicine and anesthesia. Post-Acute Focus: With more and more focus on the need to rationalize and re-organize the post-acute sector, we have seen multiple industry leaders start to evolve their strategies. I blogged yesterday about AccentCare’s interesting strategy in the...… Continue Reading Full Article Healthcare
science and technology Extending the Patentable Life of 3D Printers: A Lesson From the Pharmaceutical Industry By feedproxy.google.com Published On :: Tue, 19 Jan 2016 17:34:48 +0000 Modern innovation typically occurs one step-improvement at a time. Some clients initially question whether their new application of an existing technology is patentable. Usually, the answer is ‘yes.’ Under U.S. law (and most other jurisdictions), an innovation to an existing technology is patentable so long as at least one claim limitation is novel and non-obvious....… Continue Reading Full Article Biotechnology FDA Intellectual Property Legislation
science and technology PTO Cancer Immunotherapy Fast Track By feedproxy.google.com Published On :: Wed, 06 Jul 2016 16:33:54 +0000 In response to President Obama’s National Cancer Moonshot initiative to eliminate cancer, the USPTO has launched the “Cancer Immunotherapy Pilot Program.” The Pilot Program provides an accelerated review for applications related to cancer immunotherapy and is set to launch in July 2016. According to the USPTO, this initiative: aims to cut the time it takes to...… Continue Reading Full Article Other National Cancer Moonshot Initiative Patents USPTO
science and technology New EU Rules for Medical Devices By feedproxy.google.com Published On :: Tue, 12 Jul 2016 20:50:14 +0000 After four years of negotiations, European lawmakers agreed on June 15 on a new EU Medical Devices Regulation (MDR). The MDR is the equivalent to the FDA’s CDRH regulations in the United States and essentially specifies the applicable rules when importing medical devices into Europe, which is the world’s second-largest device market. Rules relate, for...… Continue Reading Full Article Life Sciences Practice MDR SRN UDI
science and technology En Banc: Federal Circuit Provides Guidance on Application of On-Sale Bar to Contract Manufacturers By feedproxy.google.com Published On :: Fri, 15 Jul 2016 16:04:54 +0000 Pharmaceutical and biotech companies breathed a sigh of relief Monday when the Federal Circuit unanimously ruled in a precedential opinion that the mere sale of manufacturing services to create embodiments of a patented product is not a “commercial sale” of the invention that triggers the on-sale bar of 35 U.S.C. § 102(b) (pre-AIA).[1] The en banc opinion...… Continue Reading Full Article Intellectual Property Ben Venue Laboratories CMO MedCo On-Sale Bar
science and technology Looking Forward/Looking Backward – Day 1 Notes from the JPMorgan Healthcare Conference By feedproxy.google.com Published On :: Thu, 12 Jan 2017 19:40:59 +0000 A large amount of wind, much discussion about the U.S healthcare, and the public getting soaked again – if you were thinking about Washington, DC and the new Congress, you’re 3,000 miles away from the action. This is the week of the annual JP Morgan Healthcare conference in San Francisco, with many thousands of healthcare...… Continue Reading Full Article Medicaid Medicare ASC health plan Medicare Advantage population health management Telehealth
science and technology Food for Thought (and Health): Day 2 Notes from the JP Morgan Healthcare Conference By feedproxy.google.com Published On :: Thu, 12 Jan 2017 19:45:44 +0000 Addressing the Social Determinants of Health: Is the healthcare industry pushing a rock up a hill? We collectively are trying to provide healthcare with improved quality and reduced cost, but the structure of the nation’s healthcare system remains heavily siloed with the social determinants of health often falling wholly or partly outside the mandate and...… Continue Reading Full Article Medicaid Medicare ASC health plan Medicare Advantage population health management Telehealth
science and technology The Old and the New – Day 3 Notes from the JPMorgan Healthcare Conference By feedproxy.google.com Published On :: Thu, 12 Jan 2017 19:47:02 +0000 Day 3 of the JPMorgan healthcare conference was one of striking contrasts between the old and the new. (And, by the way, the rain finally stopped for a day, but it will be back tomorrow to finish off the last day of the conference). The Old: Sitting in the Community Health Systems (CHS) presentation and...… Continue Reading Full Article Medicaid Medicare ASC health plan Medicare Advantage population health management Telehealth
science and technology Notes on Day 4 of the JPMorgan Healthcare Conference By feedproxy.google.com Published On :: Fri, 13 Jan 2017 19:06:20 +0000 Some interesting presentations on the last day of the JPMorgan Healthcare Conference that concentrated on common themes – the increasing importance of ancillary business line to bolster core business revenue and of filling in holes to achieve scale and full-service offerings. Genesis Healthcare – The largest U.S. skilled nursing facility (SNF) provider, which also is...… Continue Reading Full Article Medicaid Medicare ASC health plan Medicare Advantage population health management Telehealth
science and technology WannaCry Ransomware Alert By feedproxy.google.com Published On :: Mon, 22 May 2017 18:18:24 +0000 This is not a drill. Companies and law enforcement agencies around the world have been left scrambling after the world’s most prolific ransomware attack hit over 500,000 computers in 150 countries over a span of only 4 days. The ransomware – called WannaCry, WCry, WannaCrypt, or WannaDecryptor – infects vulnerable computers and encrypts all of...… Continue Reading Full Article Other cybersecurity ransomware
science and technology Achieving atmospheric verification of CO<sub>2</sub> emissions By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Reply to: An appeal to cost undermines food security risks of delayed mitigation By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology High climate sensitivity in CMIP6 model not supported by paleoclimate By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Climate or biodiversity? By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology An appeal to cost undermines food security risks of delayed mitigation By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Hazards in the Himalayas By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Climate-tracking species are not invasive By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Coldest Canadian Arctic communities face greatest reductions in shorefast sea ice By feeds.nature.com Published On :: 2020-05-04 Full Article
science and technology Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing By feeds.nature.com Published On :: 2020-04-27 Full Article
science and technology Critical role of histone H3 lysine 27 demethylase Kdm6b in the homeostasis and function of medullary thymic epithelial cells By feeds.nature.com Published On :: 2020-04-28 Full Article
science and technology JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction By feeds.nature.com Published On :: 2020-04-28 Full Article
science and technology CD9 induces cellular senescence and aggravates atherosclerotic plaque formation By feeds.nature.com Published On :: 2020-04-28 Full Article
science and technology Compensation between Wnt-driven tumorigenesis and cellular responses to ribosome biogenesis inhibition in the murine intestinal epithelium By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Chemical activation of SAT1 corrects diet-induced metabolic syndrome By feeds.nature.com Published On :: 2020-05-06 Full Article
science and technology Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein By feeds.nature.com Published On :: 2020-05-06 Full Article
science and technology Adipogenesis of skeletal muscle fibro/adipogenic progenitors is affected by the WNT5a/GSK3/β-catenin axis By feeds.nature.com Published On :: 2020-05-07 Full Article
science and technology Achieving atmospheric verification of CO<sub>2</sub> emissions By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Reply to: An appeal to cost undermines food security risks of delayed mitigation By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology High climate sensitivity in CMIP6 model not supported by paleoclimate By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Climate or biodiversity? By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology An appeal to cost undermines food security risks of delayed mitigation By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Hazards in the Himalayas By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Climate-tracking species are not invasive By feeds.nature.com Published On :: 2020-04-30 Full Article
science and technology Coldest Canadian Arctic communities face greatest reductions in shorefast sea ice By feeds.nature.com Published On :: 2020-05-04 Full Article
science and technology Live Imaging of Tumor Initiation in Zebrafish Larvae Reveals a Trophic Role for Leukocyte-Derived PGE2 By feeds.nature.com Published On :: Full Article
science and technology 2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy By feeds.nature.com Published On :: Full Article
science and technology First plant-made biologic approved By feeds.nature.com Published On :: 2012-06-07 Full Article
science and technology Britain aims for broad open access By feeds.nature.com Published On :: Full Article
science and technology Hemodialysis: Fish oil for hemodialysis By feeds.nature.com Published On :: 2012-05-22 Full Article
science and technology Lipids: Cardioprotective effects of HDL cholesterol called into question By feeds.nature.com Published On :: 2012-06-05 Full Article
science and technology Bacterial physiology: Another brick in the wall By feeds.nature.com Published On :: 2012-06-06 Full Article
science and technology Multiple sclerosis: Autoantibodies target guardian lipids By feeds.nature.com Published On :: 2012-06-27 Naturally occurring brain phospholipids that are targeted by autoantibodies in MS can suppress T-cell activity and ameliorate symptoms in a mouse model of the disease. Full Article
science and technology Lipids in inflammation: PUFAs cause shunt from COX to LOX By feeds.nature.com Published On :: 2012-06-27 Activation through Toll-like receptor 4 or P2X purinergic receptors of macrophages supplemented with omega-3 fatty acids induces the release of 22-carbon fatty acids that can inhibit COX-mediated eicosanoid production. Full Article
science and technology Epothilones By feeds.nature.com Published On :: 2012-06-27 These polyketides, which occur naturally in a myxobacterial species, stabilize microtubule polymers and are therefore being investigated as potential anticancer agents. Full Article
