sto Hertz's failed Tesla bet keeps getting worse as weak earnings challenge its stock By markets.businessinsider.com Published On :: Tue, 12 Nov 2024 18:22:42 +0000 The rental-car giant fell as much as 12% on Tuesday after posting a deeper-than-expected loss. Full Article Markets mi-exclusive hertz car-rental tesla electric-vehicles ev-market
sto Tesla stock could soar 50% as it broadens beyond autos and as Musk exerts more political influence, Morgan Stanley says By markets.businessinsider.com Published On :: Tue, 12 Nov 2024 18:58:58 +0000 Morgan Stanley analysts say Tesla will surge if it can expand to be an AI giant, which may be more likely if Elon Musk exerts influence in a second Trump term. Full Article Markets mi-exclusive tesla trump donald-trump tesla-stock elon-musk morgan-stanley 2024-elections tesla-stock-outlook
sto The biggest risk to stocks after Trump's victory is China's reaction to a trade war, research firm says By markets.businessinsider.com Published On :: Tue, 12 Nov 2024 19:53:19 +0000 If Trump's proposed 60% tariff against China is enacted and the country responds aggressively, it could pressure some of America's largest companies. Full Article Markets mi-exclusive stock-market-outlook china-tariffs trade-war sp-500 donald-trump
sto Stock market today: Election rally stumbles as bond yields spike ahead of key inflation data By markets.businessinsider.com Published On :: Tue, 12 Nov 2024 21:19:01 +0000 Bond yields spiked aggressively as investors awaited Wednesday's inflation data for October. Full Article Markets mi-exclusive daily-market-wrap trump-trade election trump-rally financials bitcoin bond-yields
sto A brief history of America's love affair with fluoridated water — and why it's now up for debate By www.businessinsider.com Published On :: Tue, 12 Nov 2024 21:23:05 +0000 Too much fluoride can make your teeth brown, but getting a little bit is a dentist's dream. Here's the complete history of fluoridated water. Full Article Health fluoride public-health tap-water rfk-jr donald-trump
sto Shopify's 25% gain sends Canada's benchmark stock index to all-time highs By markets.businessinsider.com Published On :: Tue, 12 Nov 2024 21:28:37 +0000 Shopify's surge added fuel to Canada's strong market rally, helping its benchmark index cross 25,000 for the first time. Full Article Markets mi-exclusive shopify q3-earnings earnings-season ecommerce shopify-stock earnings canada canadian-stocks
sto Where to watch St. Denis Medical: Live stream new series from Superstore creator By www.businessinsider.com Published On :: Tue, 12 Nov 2024 21:45:58 +0000 NBC's newest workplace sitcom is here, and we'll show you where to watch St. Denis Medical if you don't have cable. Full Article Streaming (Reviews) Reviews Entertainment streaming how-to-watch insider-reviews vpn
sto Is Yellowstone on Paramount Plus or Peacock? A viewing guide for the final episodes By www.businessinsider.com Published On :: Tue, 12 Nov 2024 23:37:01 +0000 Paramount Plus, Peacock, and the Paramount Network all have a hand in the Yellowstone franchise, but it can be tricky to stream episodes. Full Article Streaming (Reviews) Reviews Entertainment streaming insider-reviews yellowstone
sto SoftBank is Nvidia's first Blackwell chips customer. Here's what they're going to be used for. By www.businessinsider.com Published On :: Wed, 13 Nov 2024 05:39:51 +0000 The collaboration comes amid skyrocketing demand for Nvidia chips, as companies scramble to secure supplies. Full Article Tech AI nvidia softbank chips japan
sto 10 Ways to Build Customer Loyalty and Increase Retention By blog.avangate.com Published On :: Mon, 04 Feb 2019 00:00:00 +0000 Selling your services and wares online can be challenging, as today’s digital shoppers are smart and demanding. You need a customer-focused approach right from the start. The customer is the most significant pillar of modern businesses, so you need to build a genuine relationship with them if you want your online store to survive. Read […] Full Article
sto Upgraded: Stopovers in Istanbul, with free tours courtesy of Turkish Airlines By www.upgradetravelbetter.com Published On :: Thu, 24 Feb 2011 07:40:04 +0000 Sure, some airlines let you work in a free stopover. But Turkish Airlines goes one step further and offers up a free city tour on a stopover as short as six hours. Maybe getting into a shuttle bus and tooling around Istanbul after seven hours on an Airbus isn’t your cup of tea, but if […] The post Upgraded: Stopovers in Istanbul, with free tours courtesy of Turkish Airlines first appeared on UPGRADE: TRAVEL BETTER. Full Article Travel
sto News24 Business | Huawei 'super fans' annoyed at lack of supply as pricey phone hits China stores By www.news24.com Published On :: Sunday Sep 22 2024 18:30:16 Many fans of Huawei on Friday were disappointed that its much-anticipated phone, Mate XT - more than twice the price of the iPhone 16 Pro Max - was not available for walk-in customers. Full Article
sto News24 Business | Investment update | Cybersecurity is a goldmine - top picks for investors By www.news24.com Published On :: Tuesday Oct 22 2024 07:16:20 The latest investment insights and market developments. Full Article
sto News24 | Lottoland wins Google battle, Mogale City sewage disaster: Today's top 7 stories in 7 minutes By www.news24.com Published On :: Tuesday Nov 12 2024 18:32:16 News24 brings you the top stories of the day, summarised into neat little packages. Read through quickly or listen to the articles via our customised text-to-speech feature. Full Article
sto Do you like party games and music history? Try HITSTER By boingboing.net Published On :: Tue, 01 Oct 2024 16:07:57 +0000 I recently attended a weekend-long birthday getaway for an old college friend, and as soon as I arrived, he pulled out a box and said, "You have to play this game." And he was right. Hitster describes itself as a Music Party Board Game, and that's accurate. — Read the rest The post Do you like party games and music history? Try HITSTER appeared first on Boing Boing. Full Article Post 80s music 90s music board games music history party games pop music tabletop game tabletop games
sto Pesto the penguin is an adorable chonker By boingboing.net Published On :: Tue, 01 Oct 2024 16:15:00 +0000 Pesto is a baby king penguin at the SeaLife Melbourne Aquarium. At nine months old, he is the biggest penguin the aquarium has ever seen. Weighing almost fifty pounds, Pesto weighs as much as both of his parents combined and is the biggest penguin at the aquarium. — Read the rest The post Pesto the penguin is an adorable chonker appeared first on Boing Boing. Full Article Post animals australia chonkers cute Delightful Creatures penguins
sto The stunning view from Preikestolen, 604m over Norway's Lysefjorden By boingboing.net Published On :: Wed, 02 Oct 2024 11:40:41 +0000 Preikestolen, Pulpit Rock, is one of Norway's most famous natural landmarks. It's located in Rogaland county, near the town of Forsand. It overlooks the stunning Lysefjorden, a narrow fjord surrounded by steep cliffs. In this video of the 604m Rock, both the stunning beauty and dizzying height of the rock are shown. — Read the rest The post The stunning view from Preikestolen, 604m over Norway's Lysefjorden appeared first on Boing Boing. Full Article Post cliff heights travel
sto “Distraction,” Simplicity, and Running Toward Shitstorms By www.43folders.com Published On :: Tue, 05 Oct 2010 23:49:56 +0000 It can scarcely be denied that the supreme goal of all theory is to make the irreducible basic elements as simple and as few as possible without having to surrender the adequate representation of a single datum of experience. —Albert Einstein, “On the Method of Theoretical Physics” (1934) Context: Last week, I pinched off one of my typically woolly emails in response to an acquaintance whom I admire. He’s a swell guy who makes things I love, and he'd written, in part, to express concern that my recent Swift impersonation had been directed explicitly at something he'd made. Which, of course, it hadn’t—but which, as I'll try to discuss here, strikes me as irrelevant. To paraphrase Bogie, I played it for him, so now I suppose I might as well play it for you. (n.b.: Excerpted, redacted, munged, and heavily expanded from my original email) There are at least a couple things that mean a lot to me that I'm still just not very good at. Make nuanced points in whatever way they need to be made; even if that ends up seeming “un-nuanced” Never explain yourself. I want to break both these self-imposed rules privately with you here. [Editor’s Note: Um.] Because, I hope to nuance the shit out of some fairly un-nuanced points. And, to do that, I'll also (reluctantly) need to explain myself. But, here goes. First [regarding my goofing on “distraction-free writing environments”] I think there are some GIANT distinctions at play here that a lot of folks may not find nearly as obvious as I do: Tool Mastery vs. Productivity Pr0n – Finding and learning the right tools for your work vs solely dicking around with the options for those tools is just so important, but also so different. And, admittedly, it’s almost impossible to contrast those differences in terms of hard & fast rules that could be true for all people in all situations. But, that doesn’t make the difference any less qualitatively special or real. Similarly… Self-Help Vs. “Self”–“Help” – Solving the problem that caused the problem that caused the problem that caused the symptom we eventually noticed. Huge. Arguably, peerless. Viz.: How many of us ignore the actual cause of our problem in favor of just reading dozens of blog posts about how to “turbocharge” its most superficial symptoms? Sick. Focus & Play – Yes, focusing on important work is, as Ford used to say, Job 1. But, that focus benefits when we maintain the durable and unapologetic sense of play that affords true creativity and fosters an emergence of context and connection that’s usually killed by stress. BUT. Again, what conceivable “rule” could ever serve to immutably declare that “THIS goofing-off is critical for hippocampal plasticity” vs. “THAT goofing-off is just dumb, distracting bullshit?” Impossible. Because drawing those kinds of distinctions is one of our most important day-to-day responsibilities. Decisions are hard, and there’s no app or alarm gadget that can change that. Although, they certainly can help mask the depth of the underlying problem that made them seem so—what’s the parlance?—“indispensable”. Think: Elmo Band-Aids for that unsightly pancreatic tumor. Reducing Distraction through Care (Rather than braces, armatures, and puppet strings). Removing interruptions and external distractions that harm your work or life? Great. Counting on your distraction-removal tool to supplement your non-existent motivation to do work that will never get done anyway? Pathetic. Frankly, this is a big reason I'm so galled when anyone touts their tool/product/service as being the poor, misunderstood artist’s new miracle medicine—rather than just admitting they've made a slightly different spoon. Because, let’s be honest: although most of us have plenty of perfectly serviceable spoons, everybody knows collecting cutlery is way more fun than using it to swallow yucky medicine. Using a System Vs. Becoming a System. Having a system or process for getting work done vs. making the iteration of that system or process a replacement for the work. This is just…wow…big. But, maybe most importantly to me… Embracing the Impossibles. Getting past these or any other intellectual koans by simply accepting life’s innumerable and unresolvable paradoxes, hypocrisies, and impossibilities as God-given gifts of creative constraint. Rather than, say, a mimeographed page of long division problems that must be solved for a whole number, n. I just can’t ever get away from this one. For me, it’s what everything inevitably comes back to. The very definition of our jobs is to solve the right problem at the right level for the right reason—based on a combination of the best info we have for now and a clear-eyed dedication to never pushing an unnecessary rock up an avoidable hill. YET, we keep force-feeding the monster that tells us to fiddle and fart and blame the Big Cruel World whenever we face work that might threaten our fragile personal mythology. “Sigh. I wish I could finally start writing My Novel….Ooooooh, if only I had a slightly nicer pen…and Zeus loved me more….” All that stuff? That there’s a complex set of ideas to talk about for many complex reasons—not least of which being how many people either despise or (try to) deny the unavoidable impact of ol' number six. But, here’s the thing: as much as saying so pisses anybody off, I think the topics we're NOT talking about whenever we disappear into Talmudic scholarship about “full-screen mode” or “minimalist desks” or whatever constitutes a “zen habit”—those shunned topics are precisely the things that I believe are most mind-blowingly critical to our real-world happiness as humans. In fact, I believe that to such a degree that helping provide a voice for those unpopular topics that can be heard over the din is now (what passes for) my career. I really believe these deeper ideas are worth socializing on any number of levels and in many media. Even when it’s inconvenient and slightly disrespectful of someone’s business model. So, that’s what I try to do. I talk about these things. Seldom by careful design. Often poorly. But, always because they each mean an awful lot to me. […] But, no matter how I end up saying whatever the hell I say, I believe in saying it not simply to be liked or followed or revered as a “nice guy” who pushes out shit-tons of whatever to “help people.” Because, believe me, friend, a great many of those apparently “nice guys” swarming around the web “helping people” these days are ass-fucking their audience for nickels and calling it a complimentary colonoscopy. And, while I absolutely think that in itself is empirically wrong, I also think it’s just as important to say that it’s wrong. Sometimes, True Things need to be said. Which in this instance amounts to saying, a) selling people a prettier way to kinda almost but not really write is not, in the canonical sense, “nice”—but, far worse, b) leaving your starry-eyed customers with the nauseatingly misguided impression that their “distraction” originates from anyplace but their own busted-ass brain is really not “helping.” Not on any level. It is, literally, harmful. “Helping” a junkie become more efficient at keeping his syringe loaded is hardly “nice.” It’s the opposite of nice. And, it’s the opposite of helpful. These are my True Things. And, to me, saying your True Things also means not watering down the message you care about in order to render it incapable of even conceivably hurting someone’s feelings—or of even conceivably losing you even one teeny-tiny slice of that precious “market share.” Well, that’s the price, and I'm fine paying it—best money I've ever spent. But, it also means trusting your audience by letting each of them decide to add water only as they choose to—by never corrupting the actual concentrate in a way that might make it less useful to the smartest or most eager 5% of people who'd like to try using it undiluted. Because, at that point, you're not only abandoning the coolest people you have the honor of serving—you risk becoming a charlatan. And, that’s precisely what you become when you start to iteratively inbreed the kind of fucktard audience for whom daily buffets of weak swill and beige assurance are life’s most gratifying reward. Sure. Those poor bastards may never end up using any of that watery information to do anything more ambitious than turbocharging their most regrettable symptoms. But, who’s the last person in the universe who’s going to grab them by the ears and tell them to get back to work? Exactly—that same “nice guy” whose livelihood now depends on keeping infantalized strangers addicted to his “help.” Holy shit—no way could I ever live with that. It’s so wrong, it’s not even right. ESC, ESC, ESC! […] Okay. So anyhow, there’s a really long-winded, overly generous, and extremely pompous way of trying to say I don’t know how to do what I do except how I do it. But, I do genuinely feel awful when innocent people feel they have been publicly humiliated or berated simply because I'm some dick who hates people. Which has to be my favorite irony of all. When I was a kid, I thought my Mom was “mean” not to let me play in traffic on busy Galbraith Road. Today, I'm not simply grateful that she had the strength and resolve to be so “mean”—I actually can’t imagine how sad it would be to not have people in your life who care enough about your long-term welfare to tell you to stop fucking around in traffic. To where you eventually might start even seeking 12x-daily safety hacks from some of the very same drivers whose recklessness may eventually kill you. Wow. […] Admitting when life is complicated or things aren’t shiny and happy all the time strikes me as a wonderfully sane and adult way to conduct one’s life. That there are so many folks offended by even the existence of this anarchic idea is not a problem I can solve. No more than I can wish useless email away or pray hard enough that it never rains on anyone’s leaky roof. All out of scope. And, then, I jizzed on at length about how much I admire the recipient’s work. Which I do. Good work doesn’t need a cookie I may admire your work, too. Especially if you care a lot about that work and don’t overly sweat peoples' opinions of it. Most definitely including my own. For these purposes, it doesn’t really matter whether we're friends and, honestly, it doesn’t even matter whether I love, use, or agree with everything you do, say, or make in a given day. It doesn’t matter because good work doesn’t need me to love it. Like tornadoes and cold sores, good work happens with total disregard to whether I'm “into it.” But, conversely, let’s stipulate that the points-of-view undergirding our opinions—again, including mine—will and should survive either agreement or lack of agreement with equivalently effortless ease. Because, like really good work, a really good point-of-view doesn’t require another person’s benediction. Guess we'll have to disagree to agree Now, to be only vaguely clearer here, I'm not posting this circuitous ego dump in the service of altering your opinion of either me, my friend, his work, or practically anything else for that matter. But, I would love it if we could all be more okay with the fact that real life means that we do each have a different, sometimes incongruous, and often totally incompatible point-of-view. Yes. Even you have a point-of-view that someone despises. Ready to change it now? Jesus, I sure hope not. Then, to be only slightly more clear, I'm also not advocating for that fakey brand of web-based kum ba ya that gets trotted out alternately as “tolerance” or “inclusion” or some styrofoam miniature of “civility.” I'm absolutely not against all of those things when authentically practiced, but I'm also really skeptical of the well-branded peacemakers who are forever appointing themselves the Internet’s “Now-Now-Let’s-All-Pretend-We're-Just-Saying-the-Same-Useless-Thing-Here” den mothers. Because we're not all saying the same things. Not at all. And, it infantalizes some important conversations when we tacitly demand that any instance of honest disagreement be immediately horseshat into a photo opp where some thought leader gets to hoist everyone’s hands in the air like he’s fucking Jimmy Carter. Nope. Not saying that. Who will you really rely on? What I AM saying is that alllllll this seemingly unrelated stuff is absolutely related—that the pattern of not relying on other people for anything you really care about is arguably the great-grandaddy of every useful productivity, creativity, or self-help pattern. Where’s this matter? Pretty much everywhere you have any sort of stake: Don’t rely on other people to remove your totally fake “distractions.” Don’t rely on other people to pat your beret, re-tie your cravat, and make you a nice cocoa whenever that mean man on the internet points out that your “distractions” are totally fake. (Which they are) Don’t rely on other people to tell you when or whether you have enough information. Don’t rely on other people to define your job. Don’t rely on other people to “design your lifestyle.” Don’t rely on other people to decide when your opinions are acceptable. Don’t rely on other people to tell you when you're allowed to be awesome. Don’t rely on other people to make you care. Don’t even rely on other people to tell you what you should or shouldn’t rely on. Yes. I went there. Because that’s the point. These hypocrisies, paradoxes, and ambiguities that people get so wound up about—that many of us are constantly (impotently) trying to resolve—cannot be resolved. Because, yeah: all of these harrowingly unsolvable problems are immune to new notebooks and less-distracting applications and shinier systems and “nicer” self-“help” and pretty much anything else that is not, specifically, you walking straight into the angriest and least convenient shitstorm you can find and getting your ass kicked until the storm gets bored with kicking it. Then, you find an even angrier storm. Then, another. And, so on. “Get the fuck off of my obstacle, Private Pyle!” Doing that annoying hard stuff is how you grow, get better, and learn what real help looks like. Even if that’s not the answer you wanted to hear. You get better by getting your ass out of your RSS reader and fucking making things until they suck less. Not by buying apps. You don’t whine about distractions, or derail yourself over needing a nicer pencil sharpener, or aggravate your chronic creative diabetes by starting another desperate waddle to the self-help buffet. No. You work. And, for what it’s worth, just like you can’t get to the moon by eating cheese, you'll also never leave boot camp with your original scrote intact by telling your drill sergeant to try using more honey than vinegar. No. That sergeant’s job is to make you miserable. It’s his job to break down your callow conceits about what’s supposed to be easy and fair. It’s his job to emotionally pummel you into giving up and becoming a Marine. You? You're not there to give the sergeant notes; you're there to sleep two hours a night, then not mind getting beaten for 20 hours until a decent Marine starts to fall out. Who knows? He may even surprise you by introducing a surprisingly effective “distraction-free learning environment.” “Tee ell dee ahr, Professor Brainiac.” Like most humans, I like things I can understand. Like most readers, I love specificity. Like most thinkers, I love clarity. Like most students, I love relevance and practicality. And, like most busy people, believe it or not, I actually do really like it when someone gets straight to the point. But, here’s the problem. If my 2-year-old daughter asks me about time travel, and I blithely announce, “E=mc2”, I will have said something that is entirely specific, clear, relevant, practical, and/or straight-to-the-point. For somebody. But, not so much for my daughter. And, to be honest, not even to any useful degree for me. She'd probably either laugh derisively at me (which she’s great at), or she'd pause and ask, “Whuh dat?” (which she’s even better at). Thing is, her understanding that jumble of characters less than me—and my understanding it WAY less than Professor Al—has zero impact on the profundity, truth, beauty, or impact of the man’s theory. Sure. You could quite accurately fault me for being a smartass and a poseur, and you could even berate my toddler for her unaccountably shallow understanding of Modern Physics. But, in any case, you can’t really blame either Albert or his theory. You're turbocharging nothing Specifically, Albert can’t begin to tell us what he really knows if we don’t understand math. So, let’s say this theory you've been hearing about really interests you. And, let’s also pretend, just for the sake of the analogy, that you haven’t completed Calculus III (212) or Quantum Mechanics (403) or even something as elementary as, say, Advanced Astrophysics II (537). I know you have. Obviously. But, let’s pretend. Where do you start? Well, you could read some tips about learning math. You could find a list of 500 indispensable resources for indispensable math resources. You could buy a new “distraction-free math environment.” Heck, there’s actually nothing to stop you from just declaring yourself a “math expert.” Congratulations, Professor. Thing is: you still don’t know math. Which means you still can’t really understand the theory—no more than a pathetic Liberal Arts refugee like me or a dullard Physics ignoramus like my kid can really grok relativity. Difference is, you will have blown a lot of time hoping that actual expertise follows non-existent effort—while my daughter and I get to remain total novices without charge. Only, we don’t get all mad at the theory as a result; a staggering number of fake math experts do. I mean, be honest—after all that recreational non-work and make-believe dedication almost trying to kinda learn math sorta—you might actually get frustrated at how brazenly Al defies your fondness for shortcuts by continuing to rely on so many terms and proofs and blah-blah-blah that you still just don’t understand. So annoying. You may simply decide that Albert Einstein’s a huge dick for never saying things that can be completely understood solely by scanning a headline. EPIC EINSTEIN FAIL, amirite? You never really know what you didn’t know until you know it But, Al just told the truth. Problem is, Al’s truth not only requires fancy things in order to be truly understood—the more of those fancy things you take away from his truth, the less true it gets. And, by the time it’s been diluted to the point where you're comfortable that you understand it? You'd be understanding the wrong thing. Even I can understand that. But, not one bit of any of this is Al’s fault. Al doesn’t get to control who uses, abuses, gets, or doesn’t get what he said or why it matters. Especially since he’s been dead for over fifty years. All I know is, regardless of who has ears to hear it on a given day, it would be to Al’s credit never to mangle something important in order to get it into terms everybody’s ready to handle without actually trying. And God bless him for never agreeing that your “distractions” to learning math are his problem. So, yeah, if you only need to hand in a crappy 5-page paper, you could certainly Cliff’s Notes your way through Borges, Eliot, or Joyce in an afternoon, and feel like you haven’t missed a thing. Trouble is, if you did care even a little, it’s impossible to even say how much you're missing since you can’t be bothered to soldier through the source text. The text itself is the entire point. Even the wonderfully cogent and readable layman’s explanations Einstein himself provided don’t really get to the nut, the application, and the implications of his real theory. That all takes real math. That “single datum of experience” matters Sometimes, complex or difficult things stop being true when you try to make them too simple. Sometimes, you have to actually get laid to understand why people think sex is such a thing. Sometimes, you need to learn some Greek if you really want to understand The Gospel of John. And, yeah, sometimes, you're going to have to just work unbelievably hard at whatever you claim to care about before anyone can begin to help you get any better—or less “distracted”—at it. The part I really know is what doesn’t work. Reading Penthouse Forum won’t help you CLEP out of Vaginal Intercourse 101. Watching a Rankin-Bass cartoon about the Easter Bunny will teach you very little about the intricacies of transubstantiation. And, if you can’t be troubled to care so much about your work that you reflexively force distractions away, dicking around with yet another writing application will merely aggravate the problem. Ironic, huh? These quantum mechanics of personal productivity are rife with such frustrating “paradoxes.” These are True Things. Achieving expertise and doing creative work is all horribly complicated and difficult and paradoxical and frustrating and recursive and James Joyce-y—and any guide, blog, binary, guru, or “nice guy” that tries to suggest otherwise is probably giving you a complimentary colonoscopy. Do the math. Want a new syllabus? Sure: Run straight into your shitstorm, my friends. Reject the impulse to think about work, rather than finishing it. And, open your heart to the remote possibility that any mythology of personal failure that involves messiahs periodically arriving to make everything “easy” for you might not really be helping your work or your mental health or your long-standing addiction to using tools solely to ship new excuses. Learn your real math, and any slide rule will suffice. Try, make, and do until you quit noticing the tools, and if you still think you need new tools, go try, make, and do more. If you can pull off this deceptively simple and millennia-old pattern, you'll eventually find that—god by dying god—any partial truth that’s supported your treasured excuses for not working will be replaced by a no-faith-required knowledge that you're really, actually, finally getting better at something you care about. Which is just sublimely un-distracting. Dedication This article is dedicated to my friend, Greg Knauss. No, he’s not the app guy–he’s just a good man who does good work, who accidentally/unintentionally helped me write this rant. He also happens to be a fella who could teach anyone a thing or two about writing with distractions. Thanks, Greg. ”“Distraction,” Simplicity, and Running Toward Shitstorms” was written by Merlin Mann for 43Folders.com and was originally posted on October 05, 2010. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article Creative Work Distractions Features
sto Resolved: Stop Blaming the Pancake By www.43folders.com Published On :: Fri, 07 Jan 2011 16:22:44 +0000 In a classic bit from an early Seinfeld, Jerry and Elaine are at the airport, trying to pick up the rental car that Jerry had reserved. As usual, things go poorly and get awkward fast: Seinfeld - "Reservations" JERRY: I don't understand...I made a reservation. Do you have my reservation? AGENT: Yes, we do. Unfortunately, we ran out of cars. JERRY: But, the reservation keeps the car here. That's why you have the reservation. AGENT: I know why we have reservations. JERRY: I don't think you do. If you did, I'd have a car. See, you know how to take the reservation--you just don't know how to hold the reservation. And, that's really the most important part of the reservation...the holding. Anybody can just TAKE them. [grabs chaotically at air] And, how weirdly similar is that to our conflicted relationship with New Year's resolutions? In Seinfeldspeak? See, you know how to make the resolution, you just don't know how to keep the resolution. And, that's really the most important part of the resolution...the keeping. Anybody can just MAKE them! Oversimplified? Probably. But, ask yourself. Why this? And, why now? Or, why again? Welcome to Resolvers Anonymous: I'm 'Merlin M.' A few years ago, I shared a handful of stories on the failures that have led to my own cynicism about the usefulness of life-inverting resolutions. Because, yeah, I've historically been a big resolver. Here's what I said when I first suggested favoring "Fresh Starts and Modest Changes" over reinventions: Download MP3 of "Fresh Starts & Modest Changes" Five years on, I think I probably feel even more strongly about this. Partly because I've watched and read and heard the cyclical lamentations of folks who decided to use superficial totems (like new calendars) as an ad hoc coach and prime mover. And, partly because, in my capacity as a makebelieve productivity expert, I continue to see how self-defeating it is to pretend that past can ever be less than prologue--that we can each ignore yesterday's weather if we really wish hard enough for a sun-drenched day at the beach. It simply doesn't work. Companies that think they'll be Google for buying bagels. Writers who think they'll get published if they order a new pen. Obese people who think they'll become marathon runners if they pick up some new running shoes. And, regular old people with good hearts who continue to confuse new lives with new clothes. Has this worked before? Can you look back on a proud legacy of successful New Year's resolutions that would suggest you're making serious progress by repeatedly making a list about fundamental life changes while slamming prosecco and wearing a pointy paper hat? My bet is that most people who are seeing the kind of change and growth and improvement that sticks tend to avoid these sorts of dramatic, geometric attempts to leap blindly toward the mountain of perfection. I'll go further and say that the repeated compulsion to resolve and resolve and resolve is actually a terrific marker that you're not really ready to change anything in a grownup and sustainable way. You probably just want another magic wand. Otherwise you'd already be doing the things you've resolved to do. You'd already be living those changes. And, you'd already be seeing actual improvements rather than repeatedly making lists of all the ways you hope your annual hajj to the self-improvement genie will fix you. Then, of course, we make things way worse by blaming everything on our pancakes. Regarding "The First Pancake Problem" Anyone who's ever made America's favorite round and flat breakfast food is familiar with the phenomenon of The First Pancake. No matter how good a cook you are, and no matter how hard you try, the first pancake of the batch always sucks. It comes out burnt or undercooked or weirdly shaped or just oddly inedible and aesthetically displeasing. Just ask your kids. At least compared to your normal pancake--and definitely compared to the far superior second and subsequent pancakes that make the cut and get promoted to the pile destined for the breakfast table--the first one's always a disaster. I'll leave it to the physicists and foodies in the gallery to develop a unified field theory on exactly why our pancake problem crops up with such unerring dependability. But I will share an orthogonal theory: you will be a way happier and more successful cook if you just accept that your first pancake is and always will be a universally flukey mess. But, that shouldn't mean you never make another pancake. So Loud. Then, So Quiet. I offer all of this because today is January 7th, gang. And, for the past week, all over the web, legions of well-intentioned and seemingly strong-willed humans have been declaring their resolved intention to make this a year of more and better metaphorical pancakes. And, like clockwork--usually around today or maybe tomorrow--a huge cohort of those cooks will begin to abandon their resolve and go back to thinking all their pancakes have to suck. Just because that first one failed. And, as is the case every year, online and off, there won't be nearly as many breathless updates to properly bookend how poorly our annual ritual of aspirational change has fared. Which is instructive. Not because new year's resolutions are a universally bad idea. And, not because Change is Bad. And, not because we should be embarrassed about occasionally falling short of our own (frequently unreasonable) aspirations. I suspect we tout the resolution, but whisper the failure because we blame the cook. Or, worse, fingers point toward the pancake. Instead of just admitting that the resolution itself was simply unrealistic or fundamentally foreign. And, that's a shame. Remember, there's no "I" in "unreasonable" Granted, I'm merely re-repeating a point I've struggled to make (to both others and myself) for years now. But, it will bear repeating every January in perpetuity. Resist the urge to pin the fate of things you really care about to anything that's not truly yourself. The "yourself" who has a real life with complicated demands. The "yourself" who's going to face a hard slog trying to fold a new life out of a fresh calendar. Calendars are just paper and staples. They can't make you care. And they can't help you spin around like Diana Prince, and instantly turn into Wonder Woman. Especially, if you're not already a hot and magical Amazon princess. First, be reasonable. Don't set yourself up for failure by demanding things that you've never come close to achieving before. I realize this is antithetical to most self-improvement bullshit, but that's exactly the point. If you were already a viking, you wouldn't need to build a big boat. Start with where you are right now. Not with where you wish you'd been. Also, accept that the first pancake will always suck. Hell, if you've never picked up a spatula before, be cool with the fact that your first hundred pancakes might suck. This is, as I've said, huge. Failure is the sound of beginning to suck a little less. And, finally, also be clear about the sanity of the motivations underlying your expectations--step back to observe what's truly broken, derive a picture of incremental success that seems do-able, and really resolve to do whatever you can realistically do to actually get better. Rather than "something something I suddenly become all different." At this point, you have logistical options for both execution and troubleshooting: Make a modest plan that you can envision actually doing without upending your real life; Build more sturdy scaffolding for sticking with whatever plan you've chosen; Make a practice of learning to not mind the duds--including those messed-up first pancakes; Or--seriously?--just accept that you never really cared that much about making breakfast in the first place. Care is not optional. Otherwise, really, you'd never need to resolve to do anything. You'd already just be cooking a lot. Instead of being all mad and depressed about not cooking. But, please. All I really ask of you. Don't blame the pancake. It's not really the pancake's fault. Like me, the pancake just wants you to be happy. This and every other new year. ”Resolved: Stop Blaming the Pancake” was written by Merlin Mann for 43Folders.com and was originally posted on January 07, 2011. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article change is hard resolutions self-improvement
sto Celebrating Black History Month at Chatham House By www.chathamhouse.org Published On :: Wed, 02 Oct 2024 15:12:13 +0000 Celebrating Black History Month at Chatham House 24 October 2024 — 6:00PM TO 8:00PM Anonymous (not verified) 2 October 2024 Chatham House Join us for the ‘Beyond expectations: The impact and legacy of migration exhibition 2024’ exhibition and drinks reception. About the Photographer Neil Kenlock, a photographer and media professional, has lived in London since arriving from Jamaica in 1963 to join his parents. He spent the early years of his career as a professional photographer, specialising in fashion, beauty, celebrities, and the cultural lifestyles of Black people in the UK. In the late 1960s and 1970s, he captured images of the UK Black Panther movement and documented demonstrations and anti-racism protests across the country.“Neil Kenlock helps us to better understand the story of London’s Black communities and to appreciate the huge artistic and cultural impact they have had on all our lives. He is a significant photographer whose work documents a key chapter in London’s post-war history.” — Mike Seaborne, former curator of photographs at the Museum of London.About the exhibitionThis exhibition unveils a collection of photographs by Neil Kenlock, capturing Black British individuals who migrated from their homelands and settled in the UK. Curated by his daughter Emelia Kenlock, the series explores the theme of ‘expectations’ and its enduring legacy, featuring African and Caribbean subjects who brought their skills, passions, and dreams—contributions that have profoundly shaped British culture today.Reflecting on the work, Kenlock stated: “Over 50 years since the concept of ‘black excellence’ first manifested, and more than 70 years since the Windrush, I truly hope this exhibition will add to the national cultural narrative and resonate with new audiences.” Full Article
sto Lysine Propionylation and Butyrylation Are Novel Post-translational Modifications in Histones By www.mcponline.org Published On :: 2007-05-01 Yue ChenMay 1, 2007; 6:812-819Research Full Article
sto The Human Plasma Proteome: History, Character, and Diagnostic Prospects By www.mcponline.org Published On :: 2002-11-01 N. Leigh AndersonNov 1, 2002; 1:845-867Reviews/Perspectives Full Article
sto Stopping the Use of Chemical Weapons in Modern Conflicts By f1.media.brightcove.com Published On :: Fri, 25 May 2018 00:00:00 +0100 Full Article
sto Can and Should Brexit Be Stopped? By f1.media.brightcove.com Published On :: Mon, 17 Sep 2018 00:00:00 +0100 Full Article
sto Undercurrents: Episode 28 – The History of Women at Chatham House By f1.media.brightcove.com Published On :: Thu, 07 Mar 2019 00:00:00 +0000 Full Article
sto Operation Decisive Storm: Analysing Four Years of Conflict in Yemen By f1.media.brightcove.com Published On :: Thu, 21 Mar 2019 00:00:00 +0000 Full Article
sto Podcast: The Power of Viral Stories, with Professor Robert Shiller By f1.media.brightcove.com Published On :: Fri, 20 Sep 2019 00:00:00 +0100 Full Article
sto Brexit in a Historical Context: Pursuing a Global Vision at the Expense of Domestic Harmony? By f1.media.brightcove.com Published On :: Tue, 12 Nov 2019 00:00:00 +0000 Full Article
sto Screening Room: Parts of a Circle - History of the Karabakh Conflict By f1.media.brightcove.com Published On :: Tue, 18 Feb 2020 00:00:00 +0000 Full Article
sto Rafts defined: a report on the Keystone symposium on lipid rafts and cell function By www.jlr.org Published On :: 2006-07-01 Linda J. PikeJul 1, 2006; 47:1597-1598Report Full Article
sto Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein By www.jlr.org Published On :: 1997-11-01 DL BrasaemleNov 1, 1997; 38:2249-2263Articles Full Article
sto Sir David Attenborough and the BBC Studios Natural History Unit awarded Chatham House Prize 2019 for ocean advocacy By www.chathamhouse.org Published On :: Mon, 18 Nov 2019 13:13:54 +0000 Sir David Attenborough and the BBC Studios Natural History Unit awarded Chatham House Prize 2019 for ocean advocacy News Release sysadmin 18 November 2019 The 2019 Chatham House Prize is awarded to Sir David Attenborough and Julian Hector, head of BBC Studios Natural History Unit, for the galvanizing impact of the Blue Planet II series on tackling ocean plastic pollution. Full Article
sto New Chatham House History Examines our Defining Moments By www.chathamhouse.org Published On :: Mon, 18 Jan 2021 16:38:45 +0000 New Chatham House History Examines our Defining Moments News Release NCapeling 18 January 2021 'A History of Chatham House: its People and Influence from the 1920s to the 2020s' will examine the impact on policymaking of our first 100 years. Full Article
sto How can the investor community address the ‘S’ in ESG? – the role of social purpose values By www.chathamhouse.org Published On :: Mon, 18 Oct 2021 19:34:24 +0000 How can the investor community address the ‘S’ in ESG? – the role of social purpose values 16 November 2021 — 1:30PM TO 2:30PM Anonymous (not verified) 18 October 2021 Online This webinar highlights the crucial relationship between an open civic space and a profitable business environment. 2020 was a tipping point for investors to think and act more responsibly, galvanized by catalysts like the killing of George Floyd and the pandemic. There is increasing investor support for social and environmental causes. Younger investors are placing increasing emphasis on values and social issues in their investment decisions. The ‘S’ in the Environment Social and Governance (ESG) agenda is clearly gaining traction, but how far does it extend to civil and political liberties i.e. the right of citizens, NGOs and journalists to speak freely, assemble and associate which are increasingly shrinking around the world? While there is increasing focus on human rights issues such as modern slavery and supply chains, civil society space issues often fall between the cracks when investors consider ESG. This webinar also explores opportunities and challenges that arise for the investor community in terms of factoring civic space issues into their political risk and ESG analysis. To what extent are civic space issues being factored into ESG social purpose values, especially by younger investors? What is the best methodology for assessing these issues in order to ensure a common and coherent set of global standards in this area? And how can investors mitigate the risks of their activities to civic space in practice? Full Article
sto Stop codon read-through of mammalian MTCH2 leading to an unstable isoform regulates mitochondrial membrane potential [Gene Regulation] By www.jbc.org Published On :: 2020-12-11T00:06:20-08:00 Stop codon read-through (SCR) is a process of continuation of translation beyond a stop codon. This phenomenon, which occurs only in certain mRNAs under specific conditions, leads to a longer isoform with properties different from that of the canonical isoform. MTCH2, which encodes a mitochondrial protein that regulates mitochondrial metabolism, was selected as a potential read-through candidate based on evolutionary conservation observed in the proximal region of its 3' UTR. Here, we demonstrate translational read-through across two evolutionarily conserved, in-frame stop codons of MTCH2 using luminescence- and fluorescence-based assays, and by analyzing ribosome-profiling and mass spectrometry (MS) data. This phenomenon generates two isoforms, MTCH2x and MTCH2xx (single- and double-SCR products, respectively), in addition to the canonical isoform MTCH2, from the same mRNA. Our experiments revealed that a cis-acting 12-nucleotide sequence in the proximal 3' UTR of MTCH2 is the necessary signal for SCR. Functional characterization showed that MTCH2 and MTCH2x were localized to mitochondria with a long t1/2 (>36 h). However, MTCH2xx was found predominantly in the cytoplasm. This mislocalization and its unique C terminus led to increased degradation, as shown by greatly reduced t1/2 (<1 h). MTCH2 read-through–deficient cells, generated using CRISPR-Cas9, showed increased MTCH2 expression and, consistent with this, decreased mitochondrial membrane potential. Thus, double-SCR of MTCH2 regulates its own expression levels contributing toward the maintenance of normal mitochondrial membrane potential. Full Article
sto Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells [Gene Regulation] By www.jbc.org Published On :: 2020-12-25T00:06:30-08:00 The molecular mechanisms of reduced frataxin (FXN) expression in Friedreich's ataxia (FRDA) are linked to epigenetic modification of the FXN locus caused by the disease-associated GAA expansion. Here, we identify that SUV4-20 histone methyltransferases, specifically SUV4-20 H1, play an important role in the regulation of FXN expression and represent a novel therapeutic target. Using a human FXN–GAA–Luciferase repeat expansion genomic DNA reporter model of FRDA, we screened the Structural Genomics Consortium epigenetic probe collection. We found that pharmacological inhibition of the SUV4-20 methyltransferases by the tool compound A-196 increased the expression of FXN by ∼1.5-fold in the reporter cell line. In several FRDA cell lines and patient-derived primary peripheral blood mononuclear cells, A-196 increased FXN expression by up to 2-fold, an effect not seen in WT cells. SUV4-20 inhibition was accompanied by a reduction in H4K20me2 and H4K20me3 and an increase in H4K20me1, but only modest (1.4–7.8%) perturbation in genome-wide expression was observed. Finally, based on the structural activity relationship and crystal structure of A-196, novel small molecule A-196 analogs were synthesized and shown to give a 20-fold increase in potency for increasing FXN expression. Overall, our results suggest that histone methylation is important in the regulation of FXN expression and highlight SUV4-20 H1 as a potential novel therapeutic target for FRDA. Full Article
sto A Balancing Act for Europe: Stop the Migrants, Support Greece, Assuage Turkey By www.chathamhouse.org Published On :: Fri, 06 Mar 2020 16:30:44 +0000 Source The New York Times URL https://www.nytimes.com/2020/03/04/world/europe/europe-migrants-turkey-greece.ht... Release date 04 March 2020 Expert Robin Niblett In the news type Op-ed Hide date on homepage Full Article
sto Molecular basis for histone H3 “K4me3-K9me3/2” methylation pattern readout by Spindlin1 [Gene Regulation] By www.jbc.org Published On :: 2020-12-04T00:06:06-08:00 Histone recognition by “reader” modules serves as a fundamental mechanism in epigenetic regulation. Previous studies have shown that Spindlin1 is a reader of histone H3K4me3 as well as “K4me3-R8me2a” and promotes transcription of rDNA or Wnt/TCF4 target genes. Here we show that Spindlin1 also acts as a potent reader of histone H3 “K4me3-K9me3/2” bivalent methylation pattern. Calorimetric titration revealed a binding affinity of 16 nm between Spindlin1 and H3 “K4me3-K9me3” peptide, which is one to three orders of magnitude stronger than most other histone readout events at peptide level. Structural studies revealed concurrent recognition of H3K4me3 and H3K9me3/2 by aromatic pockets 2 and 1 of Spindlin1, respectively. Epigenomic profiling studies showed that Spindlin1 colocalizes with both H3K4me3 and H3K9me3 peaks in a subset of genes enriched in biological processes of transcription and its regulation. Moreover, the distribution of Spindlin1 peaks is primarily associated with H3K4me3 but not H3K9me3, which suggests that Spindlin1 is a downstream effector of H3K4me3 generated in heterochromatic regions. Collectively, our work calls attention to an intriguing function of Spindlin1 as a potent H3 “K4me3-K9me3/2” bivalent mark reader, thereby balancing gene expression and silencing in H3K9me3/2-enriched regions. Full Article
sto Plant-based 'Meat' and Cultured Meat: Revolutionizing the Livestock Sector By www.chathamhouse.org Published On :: Thu, 14 Mar 2019 13:36:54 +0000 Plant-based 'Meat' and Cultured Meat: Revolutionizing the Livestock Sector 10 April 2019 — 4:00PM TO 5:30PM Anonymous (not verified) 14 March 2019 Chatham House | 10 St James's Square | London | SW1Y 4LE Consensus is building across the scientific, environmental and public health communities that a radical shift away from excessive meat-eating patterns is urgently needed to tackle the unsustainability of the livestock sector. Recognizing the scale of the challenge ahead, public policymakers, civil society and innovators have increasingly sought to prompt shifts in consumer food choices – away from the most resource-intensive meat products and towards more sustainable alternatives.Meat analogues – plant-based ‘meat’ and cultured meat also known as ‘lab-grown’ meat – mark a departure from traditional meat alternatives. Both are intended to be indistinguishable from – and in the case of cultured meat biologically equivalent to – animal-derived meat and are marketed principally at meat-eaters. Innovation and investment in meat analogues have increased significantly, but the direction and pace of growth in the meat analogue industry will depend upon a multitude of factors, including public acceptance, civil society support and incumbent industry responses.This event will explore the challenges of scaling up production and generating demand for meat alternatives. It will also look at the ways policymakers in the UK and EU can impact the direction of the industry while examining what factors will influence consumer acceptance of plant-based ‘meat’ and cultured meat as substitutes for animal-derived meat. Full Article
sto Net Zero and Beyond: What Role for Bioenergy with Carbon Capture and Storage? By www.chathamhouse.org Published On :: Mon, 06 Jan 2020 13:55:01 +0000 Net Zero and Beyond: What Role for Bioenergy with Carbon Capture and Storage? 23 January 2020 — 8:30AM TO 10:00AM Anonymous (not verified) 6 January 2020 Chatham House | 10 St James's Square | London | SW1Y 4LE In the context of the feasibility of reducing greenhouse gas emissions to net zero, policymakers are beginning to pay more attention to options for removing carbon dioxide from the atmosphere. A wide range of potential carbon dioxide removal (CDR) options are currently being discussed and modelled though the most prominent among them are bioenergy with carbon capture and storage (BECCS) and afforestation and reforestation.There are many reasons to question the reliance on BECCS assumed in the models including the carbon balances achievable, its substantial needs for land, water and other inputs and technically and economically viable carbon capture and storage technologies.This meeting will examine the potentials and challenges of BECCS in the context of other CDR and emissions abatement options. It will discuss the requisite policy and regulatory frameworks to minimize sustainability and socio-political risks of CDR approaches while also avoiding overshooting climate goals.Attendance at this event is by invitation only. Full Article
sto Putting the Hong Kong Crisis into Historical and Comparative Perspective By www.chathamhouse.org Published On :: Thu, 17 Oct 2019 15:30:01 +0000 Putting the Hong Kong Crisis into Historical and Comparative Perspective 14 November 2019 — 8:30AM TO 9:30AM Anonymous (not verified) 17 October 2019 Chatham House | 10 St James's Square | London | SW1Y 4LE This roundtable will focus on current events unfolding in Hong Kong, where the territory has been convulsed with protests for several months.The speakers will examine how class, race and poverty play into the conflict. Taking a comparative approach, they will examine the generational divide, looking at the ideological gulf between the older, more conservative and pro-Beijing population versus the younger, more pro-democracy protesters. The discussion will also draw upon the erosion of trust between police and the wider public.While acknowledging the unique features of this wave of unrest, the speakers will draw parallels, placing the current crisis in Hong Kong beside events that have occurred in other periods and other places. Parallels to be explored include those with Shanghai struggles of the 1910s through 1980s and upheavals and crackdowns in the former Soviet bloc during the Cold War. Full Article
sto The history of model railroading the the Walthers 1970 O Scale Catalog By www.flickr.com Published On :: Tue, 12 Nov 2024 07:38:05 -0800 Tangled Bank posted a photo: Full Article
sto The history of model railroading the the Walthers 1970 O Scale Catalog By www.flickr.com Published On :: Tue, 12 Nov 2024 07:38:03 -0800 Tangled Bank posted a photo: Full Article
sto The history of model railroading the the Walthers 1970 O Scale Catalog By www.flickr.com Published On :: Tue, 12 Nov 2024 07:38:01 -0800 Tangled Bank posted a photo: Full Article
sto COMAC says Air China is the first customer for C929 widebody jet By finance.yahoo.com Published On :: 2024-11-12T04:03:58Z Full Article
sto Woman, 23, had a 'burning sensation' in her stomach. It was the first sign of a rare cancer By www.yahoo.com Published On :: 2024-11-11T22:54:21Z Full Article
sto Woman in custody after allegedly stabbing boyfriend in Los Angeles By www.yahoo.com Published On :: 2024-11-12T14:00:11Z Full Article
sto Warren Buffett Told Young Investors To Buy Homes Instead Of Stocks, Calling 30-Year Mortgages 'A Terrific Deal' By finance.yahoo.com Published On :: 2024-11-12T16:09:18Z Full Article
sto Vietnam expands chip packaging footprint as investors reduce China links By finance.yahoo.com Published On :: 2024-11-12T06:07:47Z Full Article
sto Beyoncé makes Grammy history By jamaica-star.com Published On :: Mon, 11 Nov 2024 05:01:15 -0500 NEW YORK (AP): When it comes to the 2025 Grammy Award nominations, Cowboy Carter rules. Its superstar singer, Beyonce, leads the nods with 11, bringing her career total to 99 nominations. That makes her the most nominated artiste in Grammy history... Full Article