synthesis Visible-light heterogeneous photocatalysis with an ionic porous organic polymer (IPOP): synthesis of β-keto sulfoxides and benzothiophene diesters by tandem radical addition–oxidation reactions By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01382D, Research ArticleAjay Kumar Sahoo, Parag Tamuly, Jarugu Narasimha MoorthyAn IPOP, constructed constructed from cyanuric chloride and the readily accessible 2,5-di(pyridin-4-yl)thiazolo[5,4-d]thiazole (BpyTzTz), is shown to exhibit excellent visible light absorption and serve as a metal-free heterogeneous photocatalyst.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synergy of prediction rule and total synthesis in solving the stereochemical puzzle of eucalactam B By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01777C, Research ArticleChenqi Wang, Junyang Liu, Tao YeThe absolute configurations of the fungal-derived reduced polyketide eucalactam B were initially predicted using the “Biochemistry-based rule” and later confirmed through its first successful total synthesis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Facile one-pot synthesis of novel imidates as multifunctional organic fluorescent materials By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01628A, Research ArticleFeng-Ting Liu, Shuo Wang, Yong-Shun Chen, Jun-Ying Miao, Bao-Xiang Zhao, Zhao-Min LinA novel one-pot synthesis of multifunctional organic fluorescent imidates from quinolinium salt derivatives, nitrosoarenes and alcohols was presented. This method had a wide substrate scope and excellent isolated yields.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Palladium-catalyzed synthesis of indene-1-acetates via sequential double carbopalladation and aryloxycarbonylation By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01570C, Research ArticleFei Sun, Yiyi Zheng, Zhongyao Jiang, Mingxia Wu, Zeng Lv, Hongsen Ji, Xin-Xing WuA novel palladium-catalyzed cascade reaction of o-iodostyrenes, internal alkynes and formates to access various indene-1-acetates through sequential double carbopalladation and aryloxycarbonylation under a palladium/air system was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of bambusurils with perfluoroalkylthiobenzyl groups as highly potent halide receptors By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01746C, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Matúš Chvojka, Hennie Valkenier, Vladimír ŠindelářFour new fluorinated bambusuril macrocycles were prepared to show exceptional high binding affinity towards halide anions in acetonitrile.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Towards the total synthesis of mandelalide B: construction of the tetrahydrofuran/α-hydroxyl lactone fragment By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6353-6357DOI: 10.1039/D4QO01433B, Research ArticleJia-Lei Yan, Jie Yu, Yingying Cheng, Mingze Yang, Zhengshuang Xu, Tao YeA stereocontrolled synthesis of the tetrahydrofuran/α-hydroxy lactone fragment of mandelalide B has been accomplished. The synthesis features a Horner-Wadsworth-Emmons fragment assembly strategy and a highly stereospecific iodine-induced cyclization.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Total synthesis of spiro Ganoderma meroterpenoids spiroapplanatumines B, D, F, and H By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6333-6339DOI: 10.1039/D4QO01147C, Research ArticleJia-Hao Zhang, Wen-Cai Luo, Wen-Tao Chen, Yu-Tao He, Ya-Jian HuThe first total synthesis of spiroapplanatumines B, D, F, and H as well as the possibly undiscovered natural product spiroapplanatumine R has been achieved.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Transition-metal-catalyzed regiodivergent sulfonylation of aziridrines for the synthesis of β-amino sulfones By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6340-6346DOI: 10.1039/D4QO01376J, Research ArticleQinqiong Zeng, Yujia Gong, Xiaochun He, Xuemei Zhang, Zhong LianWe developed the first transition-metal-catalyzed, regiodivergent sulfonylation of aziridines, enabling the efficient synthesis of diverse β-amino sulfones under mild conditions with broad substrate compatibility and high regioselectivity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Asymmetric synthesis of (aza)flavanones by the evolution of CarOx ligands By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6444-6449DOI: 10.1039/D4QO01345J, Research ArticleJuan Yang, Wenlong Kong, Mingxin Chang, Jixing Lai, Shengkun LiAmino-pyridine-oxazoline (NHPyOx) is conceived as an unprecedented model via the core-emulating optimization of CarOx ligands.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Design, synthesis and application of bipyridine-N,N'-dioxide catalysts in asymmetric synthesis of chiral cyclopropanes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6470-6476DOI: 10.1039/D4QO01532K, Research ArticleXiaoying Cao, Xue Tian, Minmin Liu, Shi-Wu LiA novel type of highly efficient chiral C2-symmetric bipyridine-N,N'-dioxide ligands was prepared and successfully applied in the synthesis of optically pure 1,2,3-trisubstituted cyclopropanes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Recent advances in asymmetric synthesis of chiral benzoheterocycles via Earth-abundant metal catalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6534-6557DOI: 10.1039/D4QO01686F, Review ArticleJinhui Cai, Wenting Zhang, Usman Muhammad, Weishuang Li, Yanjun XieThis review mainly focus on the assembly of chiral benzoheterocycles, such as dihydrobenzofurans, chromans, indolines, tetrahydroquinolines, etc., via Earth-abundant metal-catalyzed (Cu, Fe, Ni, and Ti) asymmetric synthesis in the last few decades.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis A two-step Kinugasa/Conia-ene-type sequential reaction for the asymmetric synthesis of 8-methylene-2,6-diazaspiro[3.4]octane-1,5-diones By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01388C, Research ArticleShanyue Li, Qicai Ma, Bohua Wu, Haowen Ma, Wei Zhou, Qian CaiA two-step Kinugasa/Conia-ene-type sequential reaction is developed. The process provided a simple and efficient access to chiral 8-methylene-2,6-diazaspiro[3.4]octane-1,5-diones.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis DABSO-Mediated Pummerer Reaction Enables One-Pot Synthesis of Pyrroloquinolines for Accessing Marinoquinolines: Mechanistic, Photophysical and Pharmacological Investigations By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO01512F, Research ArticleRahimuddin Khan, Dipun Kumar Penthi, Aditi Chatterjee, Chandrakanta Sahoo, Shanti Gopal Patra, Viswanathan Arun Nagaraj, Tabrez KhanA new one-pot acid- and exogenous oxidant-free synthesis of pyrrolo[2,3-c]quinolines has been developed. The strategy involves chemoselective reduction of the 3-(2-nitrophenyl)-1H-pyrroles (pyrrolnitrin derivatives) and subsequent DABSO-facilitated Pummerer reaction in the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Charge Transfer Complex Enabled Mechanochemical Synthesis of Chalcogenoacetylenes via Alkynyl Radicals By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO01827C, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Fang Tan, Chang-Zhen Fang, Bing-Sheng Qiu, He Sheng, Yong-Liang Tu, Xiang-Yu ChenMechanochemistry has become an appealing strategy to enable numerous organic transformations. While significant advances have been achieved, the radical coupling reaction under mechanochemical conditions is still in its infancy. In...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Copper(II)-catalyzed synthesis of sulfonyl-functionalized quinone-fused cyclopenta[b]indoles via four-component cascade annulation By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01560F, Research ArticleHong Xu, Jie Liao, Fei Ren, Chuan-Rong Zhou, Xiao-Zhuo Liu, Yao Xiao, Dong-Wei Hang, Fuyu Li, Bei Wang, Ji-Yu WangThrough crucial selective radical tandem process and intramolecular nucleophilic addition, a facile copper-catalyzed four-component cascade has been realized to selectively construct novel sulfonyl-functionalized quinone-fused cyclopenta[b]indole.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Facile single-step synthesis of pentaaryl-substituted pyrano[3,2-b]pyrrol-5(1H)-ones showing aggregation-induced emission By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01600A, Research ArticleYongfeng Wang, Ruijun Chu, Yanxiao Wang, Mengyuan Zhou, Yuan Chen, Cheng Xu, Jingyu Sun, Guodong YinA novel class of heterocyclic AIEgens has been synthesized via a multicomponent reaction of isatins, 2,3-diaryl cyclopropenones, and alkyl bromides.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Catalytic asymmetric synthesis of chiral sulfilimines via S-C bond formation By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO01963F, HighlightYingying Shi, Shuiyun Zheng, Jiapian Huang, Fu-Sheng He, Min Yang, Jie WuAs the aza-analogues of sulfoxides, sulfilimines bearing S(IV) stereogenic centers hold tremendous potential in synthetic chemistry and medicinal chemistry. However, the catalytic asymmetric synthesis of chiral sulfilimines are much less...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Stereocontrolled synthesis of heterocycles from unactivated alkynes by photoredox/nickel dual-catalyzed cyclization By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01627K, Research ArticleBo-Rong Leng, Feng Yang, Jin-Lian Bai, Yu-Wen Huang, Qing-Quan Liu, Ping Wei, De-Cai Wang, Yi-Long ZhuWe report a nickel/photoredox dual catalysis method for synthesizing heterocyclics from unactivated alkynes and aryl iodides, offering a direct, selective, and green alternative to traditional synthesis with potential in medicinal chemistry.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Integrating electrocatalysis with biocatalysis for asymmetric synthesis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01899K, HighlightYuqi Lin, Jiage Yu, Ke-Yin YeThis highlight presents recent advances in asymmetric synthesis that integrate electrocatalysis with biocatalysis and discusses future development directions in this field.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o-bromobenzoic acids for the synthesis of fused isoquinolinones By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01573H, Research ArticleZhaolin Quan, Yubo Duan, Zhengkai ChenA straightforward approach for the preparation of fused isoquinolinone derivatives via palladium-catalyzed cascade decarboxylative cyclization of alkyne-tethered aryl iodides with o-bromobenzoic acids is described.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of oxa-bridged carbocycles via rhodium/Lewis acid catalyzed [3 + 3] and [4 + 3] cycloadditions of carbonyl ylides with donor–acceptor strained carbocycles By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01831A, Research ArticleJiale Li, Lingfei Wang, Pei-Nian Liu, Xingguang LiA method for cooperative rhodium/Lewis acid-catalyzed cycloadditions of carbonyl ylides with donor–acceptor (D–A) strained carbocycles is described. It affords structurally diverse oxa-bridged carbocycles with high efficiency and stereoselectivity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Rh-Catalysed Hydroacyloxylation of Cyclopropenes: Regio- and Diastereoselective Synthesis of Acyloxycyclopropanes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO01810A, Research ArticleÁngel Manu Martínez, Gema Domínguez, Ines Alonso, Marta Palaín, Javier Perez-CastellsCyclopropyl carboxylates are essential building blocks in biological and medicinal chemistry. However, their accessibility is severely limited by the need to pre-synthesise highly reactive cyclopropane derivatives. Herein, we report an...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis PIFA-Mediated cyclization of methyl(2-(1-phenylvinyl)phenyl)sulfane for the concise, flexible, and scalable de novo synthesis of C3-arylated benzo[b]thiophenes By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Accepted ManuscriptDOI: 10.1039/D4QO01589D, Research ArticleXinya Liu, Olivier Provot, Christine Tran, Jean-Francois Soule, Abdallah HamzeThe well-decorated arylated benzo[b]thiophene scaffold is a pivotal structural motif with diverse applications in medicinal chemistry. This paper outlines a de novo synthesis of C3-arylated benzo[b]thiophenes, showcasing its flexibility and...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Rhodium-catalyzed synthesis of N-substituted 3-acylpyrroles from enaminones and vinylene carbonate By pubs.rsc.org Published On :: Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D4QO01816H, Research ArticleSheng-Jiao Yan, Jian-Bo Ma, Yi-Mai Yin, Xing-Mei Hu, Bi-Na Shao, Kun Huang, Qing-Sheng ZhaoSkeletal editing is a highly efficient strategy for modifying the core scaffolds of drug molecules, with multi-atomic editing as an emergent approach. Herein, we present a protocol for constructing N-substituted...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Intermolecular Defluorinative 1,2-Diamination of Fluoroalkenyl Iodides with Sulfonamides: Synthesis of Acyclic and Cyclic Fluorinated 1,2-Enediamines By pubs.rsc.org Published On :: Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D4QO01913J, Research ArticleXue-Qiang Chu, Yu-Lan Chen, Chi Zhang, Xue-Ying Huang, Yu Ding, Danhua Ge, Zhi-Liang ShenAlkene diamination represents one of the most straightforward strategies for 1,2-diamine derivatives synthesis. However, transition-metal-free 1,2-diamination of fluoroalkenes has been less studied. Here we report an intermolecular defluorinative vicinal diamination...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of F127-GA@ZnO nanogel as a cisplatin drug delivery pH-sensitive system By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35005-35020DOI: 10.1039/D4RA06514J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nguyen Ngoc Son, Vu Minh Thanh, Nguyen Thi HuongIn this study, a novel drug delivery system based on zinc oxide nanoparticles (ZnO NPs) was developed for the enhanced delivery of cisplatin (CPT) to improve cancer treatment.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis and antibiotic potential of myxocoumarin-inspired chromene dione analogs By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35215-35219DOI: 10.1039/D4RA05941G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Antonia Behnsen, Gesa Hertrampf, Sandra Vojnović, Jasmina Nikodinović-Runić, Tobias A. M. GulderThe myxocoumarins are natural products with strong antibiotic activity. We herein explored structural simplification of the myxocoumarins while aiming to retain their antibacterial properties. This led to the discovery of potent myxochromene diones.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Design, synthesis, biological evaluation, and in silico studies of novel N-substituted-2-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazole-6-carboxamides as promising anticancer agents By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35323-35335DOI: 10.1039/D4RA04492D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Navid Dastyafteh, Manica Negahdaripour, Mohammad Hosein Sayahi, Mina Emami, Younes Ghasemi, Elham Safaei, Homa Azizian, Zahra Pakrouh Jahromi, Mehdi Asadi, Mohammad Reza Mohajeri-Tehrani, Fateme Zare, Minoo Shahidi, Zahra Pooraskari, Sayed Mahmoud Sajjadi-Jazi, Bagher Larijani, Mohammad Mahdavi, Sara RanjbarSynthesis and cytotoxicity evaluation of novel benzimidazoles were explained. The most potent derivative was subjected to cell cycle, apoptosis, and in silico investigations. Compound 5o proved to be a promising anticancer agent.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis A mild and convenient protocol for the synthesis of quinoxalin-2(1H)-ones and benzimidazoles By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35386-35390DOI: 10.1039/D4RA06887D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zhenbiao Luo, Mingyuan Wang, Guidong Jiang, Xinye Wang, Liang Zhao, Zhihui Hu, Honghe Li, Qing JiWe present a mild and simple method for the cyclization of N-protected o-phenylenediamines with carbonyl compounds in the presence of trifluoroacetic acid.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis, optical, electrochemical, and computational study of benzene/thiophene based D–π–A chromophores By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35424-35437DOI: 10.1039/D4RA02668C, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Michaela Babejová, Iveta Třísková, Libuše Trnková, Hugo Semrád, Markéta Munzarová, Dominik Heger, Dana Nachtigallová, Milan PotáčekSynthesis of novel (D–π–A) chromophores with one electron-donating + withdrawing group at opposite ends of terphenyl, terthiophene, or 2,5-diphenylthiophene, analysed upon results of HOMO–LUMO gaps, determined via CV and in terms of MO via DFT.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Enhancing skin delivery of tranexamic acid via esterification: synthesis and evaluation of alkyl ester derivatives By pubs.rsc.org Published On :: RSC Adv., 2024, 14,34996-35004DOI: 10.1039/D4RA06266C, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yutong Zeng, Mengrui Ma, Yongfeng Chen, Huichao Xie, Pingtian Ding, Keda ZhangAn alkyl esterification prodrug strategy enhances skin penetration and deposition of tranexamic acid.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis N-doped carbon quantum dots for the selective detection of OCl− ions, bioimaging, and the production of Fe3O4 nanoparticles utilized in the synthesis of substituted imidazole By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35448-35459DOI: 10.1039/D4RA06474G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Namrata Priyadarshini Hota, Sathiyanarayanan Kulathu IyerNitrogen-doped quantum dots (NCQD) were synthesized by solvothermal means using o-phenylenediamine and L-tartaric acid.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis, structure, and superconductivity of La7+2xSr1−4xKxNaxCu4O16−δ By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35391-35399DOI: 10.1039/D4RA06045H, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Deyang Xu, Guohong Cai, Peiliang Huang, Xi Wu, Yan Wang, Jinling Geng, Jing Ju, Xiaoge Wang, Congling Yin, Guobao LiT zero c for the equivalent doping La7+2xSr1−4xKxNaxCu4O16−δ system does not remain constant with an increase in x but first increases from 14.8 K for x = 0.00 to 33.9 K for x = 0.10 and then decreases to 18.5 K for x = 0.175.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Design, synthesis, and evaluation of novel thiadiazole derivatives as potent VEGFR-2 inhibitors: a comprehensive in vitro and in silico study By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35505-35519DOI: 10.1039/D4RA04158E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ibrahim H. Eissa, Walid E. Elgammal, Hazem A. Mahdy, Susi Zara, Simone Carradori, Dalal Z. Husein, Maymounah N. Alharthi, Ibrahim M. Ibrahim, Eslam B. Elkaeed, Hazem Elkady, Ahmed M. MetwalyThis study aims to investigate the potential of designed 2,3-dihydro-1,3,4-thiadiazole derivatives as anti-proliferative agents targeting VEGFR-2, utilizing a multidimensional approach combining in vitro and in silico analyses.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Low temperature synthesis of franklinite stabilized cefixime as a multifunctional nanoformulation By pubs.rsc.org Published On :: RSC Adv., 2024, 14,34156-34164DOI: 10.1039/D4RA06435F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Amna Munsaf, Muhammad Naeem Ahmed, Aroosa Zafar, Bilal Akram, Mahmoud A. A. IbrahimCefixime, an antibiotic with low solubility, stability, bioavailability and therapeutic effectiveness, needs to be administered in larger doses for effective treatment.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Design, synthesis, and in vitro and in vivo biological evaluation of triazolopyrimidine hybrids as multitarget directed anticancer agents By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35239-35254DOI: 10.1039/D4RA06704E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Heba A. Adawy, Samar S. Tawfik, Abdullah A. Elgazar, Khalid B. Selim, Fatma E. GodaIn response to the urgent need for new anti-proliferative agents, four novel series of triazolopyrimidine compounds (7a–e, 9a–d, 11a–f, and 13a–e) were synthesized and evaluated for in vitro and in vivo anticancer efficacy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Investigation and development of novel synthetic approaches for synthesis of euxanthone and derived dyes By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35601-35609DOI: 10.1039/D4RA06475E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.M. Mustafa CetinThis work explores new synthetic methods for euxanthone and its derived dye Indian yellow through euxanthic acid formation, confirming structures with analytical techniques and proposing a mechanism for the euxanthone synthesis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis and antiproliferative activity of 2-oxo-3-phenylquinoxaline derivatives and related compounds against colon cancer By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35679-35695DOI: 10.1039/D4RA06822J, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.M. S. Gomaa, Abdulghany H. A. Ahmed, S. M. El Rayes, Ibrahim A. I. Ali, Walid Fathalla, Mansour S. Alturki, Abdulaziz Hassan Al Khzem, Atiah H. Almalki, Mohammed F. Aldawsari, F. H. Pottoo, Firdos A. Khan, Mohd AmirThe impact of compound 7j on colon cancer cells (HCT-116). Fig. (A) shows the control cells Fig. (B) shows the treatment cells. The arrows show chromatin condensation, nuclear augmentation, and formation of apoptotic bodies.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis and characterization of carbonyl functionalized organotellurium(IV) derivatives By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35650-35656DOI: 10.1039/D4RA06023G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Puspendra Singh, Mariya Khan, Andrew Duthie, Ray J. ButcherAryltellurium trichlorides, ArTeCl3 (Ar = C6H5, Ph; 4-Me-C6H4, p-Tol; 1-C10H7, 1-Nap; 2,4,6-Me3C6H2, Mes) react under mild conditions with acetylacetone/benzoylacetone to give carbonyl functionalized organotellurium(IV) derivatives.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of supramolecular polymers with calix[4]arene and β-cyclodextrin and their application in heavy metal ion absorption By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35697-35703DOI: 10.1039/D4RA05559D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jian-Jian Bian, Shi-Jin Tang, Jiao Miao, Rui Lin, Guo-Li Huang, Ming-Yu Teng, Xiao-Mei LiTwo categories of supramolecular polymer monomers were produced by introducing the ureidopyrimidone quadruple-hydrogen bonding assemblies on the calix[4]arene and the β-cyclodextrin host units, which adsorbed up to 99% of Pb2+ and Cd2+.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis and in vitro assessment of gold nanoparticles conjugated with extracts, sterols and pure compounds derived from marine sponges from the Indian and Pacific Oceans By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36115-36131DOI: 10.1039/D4RA04068F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Avin Ramanjooloo, Devesh Bekah, Samson A. Adeyemi, Philemon Ubanako, Lindokuhle Ngema, Yahya E. Choonara, David E. Williams, Elena A. Polishchuk, Raymond J. Andersen, Archana Bhaw-LuximonThe synthesis of gold nanoparticles using extracts, sterols and pure compounds from marine sponges.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of Cu/Mn/Ce polymetallic oxide catalysts and catalytic ozone treatment of wastewater By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35993-36004DOI: 10.1039/D4RA06052K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jinlong Zhong, Xue feng Mao, Guanyu Wang, Heng Li, Junfang Li, Sijian Qu, Jianwei ZhaoNon-homogeneous ozone-catalyzed oxidation technology is one of the effective ways of treating wastewater, the core of which lies in the development of efficient ozone oxidation catalysts.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of new-type, cost-effective and insensitive energetic materials via nitration of solid bituminous hydrocarbons By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35971-35979DOI: 10.1039/D4RA06329E, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sahar Abdolahi, Mohammad Soleiman-BeigiA global trend for the development of energetic materials using various sources is promoted by researchers annually.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis From e-waste to eco-sensors: synthesis of reduced graphene oxide/ZnO from discarded batteries for a rapid electrochemical bisphenol A sensor By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36073-36083DOI: 10.1039/D4RA04046E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Md Humayun Kabir, Md Yeasin Pabel, Nishat Tasnim Bristy, Md. Abdus Salam, Muhammad Shahriar Bashar, Sabina YasminE-waste-derived reduced graphene oxide/ZnO forfast electrochemical detection of bisphenol A (BPA).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis A facile synthesis of iron oxide nanoparticles as a nano-sensor to detect levofloxacin and ciprofloxacin in human blood and evaluation of their biological activities By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36093-36100DOI: 10.1039/D4RA05024J, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Erum Hasan, Ziana Manzar, Nabeel Haroon, Ali Raza, Syed Nawazish Ali, Mehreen Lateef, Sabira BegumNew bioactive magnetic nanoparticles were synthesized and stabilized by 3-aminobenzoic acid (3-ABA) utilized in detection of levofloxacin and ciprofloxacin.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis A safe and efficient synthesis of N-Boc-β3-amino acid methyl esters from α-amino acids: applications in the formal synthesis of sedum alkaloids By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36016-36021DOI: 10.1039/D4RA07506D, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Bohua Long, Lijie Ren, Mengmeng Jiang, Shengquan Hu, Qianqian Jiang, Limin Li, Xuanluan Chen, Zhengzhi Wuβ3-Amino acids are essential components in the synthesis of biologically active compounds.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Chitosan supported ionic liquid, a multifaceted catalyst for streamlined and efficient synthesis of carboxylic, amino acid and carbohydrate esters By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36193-36208DOI: 10.1039/D4RA05725B, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Praachi Kakati, Satish Kumar AwasthiDevelopment of a solid heterogeneous catalyst in the form of an ionic liquid incorporated in chitosan which shows high recyclability. This was used in a solvent free esterification reaction of carboxylic acids, amino acids and carbohydrates.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Improving the catalytic performance of Co/BaCeO3 catalyst for ammonia synthesis by Y-modification of the perovskite-type support By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36281-36294DOI: 10.1039/D4RA06251E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Magdalena Zybert, Hubert Ronduda, Wojciech Patkowski, Andrzej Ostrowski, Kamil Sobczak, Wioletta Raróg-PileckaThe beneficial effect of Y3+ ions incorporated into BaCeO3 support structure stems from the strengthening of the electron-donating ability, i.e., better charge transfer from the support to the active metal, enhancing N2 dissociation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis Synthesis of green fluorescent carbon dots and their application in mercury ion detection By pubs.rsc.org Published On :: RSC Adv., 2024, 14,36273-36280DOI: 10.1039/D4RA06635A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Juan Hou, Qinqin Chen, Xiangzhi Meng, Huiling Liu, Wei FengGreen fluorescent carbon dots were prepared for effective detection of Hg2+ ions through fluorescence quenching, demonstrating high sensitivity and selectivity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
synthesis An octanuclear 3-phenyl-5-(2-pyridyl)pyrazolate/phenylsilsesquioxane complex: synthesis, unique structure, and catalytic activity By pubs.rsc.org Published On :: Dalton Trans., 2024, Accepted ManuscriptDOI: 10.1039/D4DT02690J, CommunicationAlexey Bilyachenko, Victor N Khrustalev, Zhibin Huang, Lidia S. Shul'pina, Pavel Dorovatovskii, Elena Shubina, Nikolay S. Ikonnikov, Nikolai N. Lobanov, Karim G. Rahimov, Di SunFirst metallasilsesquioxane bearing pyrazolylpyridine ligands, Cu8-based complex 1, adopts cage structure with two zigzag-like copper tetramers sandwiched by two cyclic Si5 silsesquioxane ligands. Four 3-phenyl-5-(2-pyridyl)pyrazolate ligands in 1 exhibit dual...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article