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Remo: Heroine worship

‘Remo’ is less about convincing us that a man can become a woman than reminding us Sivakarthikeyan has become a star.




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Zardozi Embroidery

A pantheon of craftsmen and their art are on display at Kaivalam, under way in Chennai. Rashmi R.D. introduces us to some Living Legends of Indian crafts. Meet Mohammad Bilal




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PIX: Sajid Khan's heroics save the day for Pakistan

IMAGES from Day 2 of the second Test played between Pakistan and England in Multan on Wednesday.




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PIX: Noman's heroics lead Pak to series-leveling win

Pakistan beat England by 152 runs in the second Test in Multan on Friday to level the three-match series at 1-1.




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Android or Alangudi




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Microencapsulation of broccoli sulforaphane using whey and pea protein: in vitro dynamic gastrointestinal digestion and intestinal absorption by Caco-2-HT29-MTX-E12 cells

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03446E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ali Ali Redha, Luciana Torquati, John R. Bows, Michael J. Gidley, Daniel Cozzolino
Sulforaphane-rich extract was prepared from broccoli. The extract was encapsulated with whey and pea protein isolates by freeze-drying. The products were characterised and assessed for in vitro bioaccessibility and bioavailability.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Impact of pH on the fabrication of egg white reinforced soy protein composite microgels for gastrointestinal delivery purposes

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO03997A, Paper
Feng Liu, Yi Liu, Suyun Zhang, Gang Liu, Christos Ritzoulis, Yue Zhang
Protein molecules such as soy protein isolate (SPI) and egg white (EW) are highly promising materials for developing hydrogels (especially micro/nanogels) for the encapsulation, protection and controlled release of bioactive substances.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Alleviating effect of whey protein supplementation on oxidative stress in hypothyroidism

Food Funct., 2024, 15,11158-11168
DOI: 10.1039/D4FO03186E, Paper
Ann Liya Sajan, Jenat Pazheparambil Jerom, Bhagyasree Rajasekharan Nair, Devanandana Dileep Kumar Sajitha, Reshma Soman, Ajmal Jalal, Raveendran Harikumaran Nair
Supplementation with whey protein is effective for treating hypothyroidism-associated oxidative stress by enhancing the antioxidant system, reducing lipid peroxidation and maintaining cellular ionic balance.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The co-fermentation of whole-grain black barley and quinoa improves murine cognitive impairment induced by a high-fat diet via altering gut microbial ecology and suppressing neuroinflammation

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO02704C, Paper
Fenfen Wei, Huibin Jiang, Chuang Zhu, Lingyue Zhong, Zihan Lin, Yan Wu, Lihua Song
A high-fat diet (HFD) is associated with various adverse health outcomes, including cognitive impairment and an elevated risk of neurodegenerative conditions.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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In vitro gastrointestinal digestion of marine oil emulsions and liposomal solutions: fate of LC-PUFAs upon lipolysis

Food Funct., 2024, 15,11291-11304
DOI: 10.1039/D4FO03161J, Paper
Open Access
Sawsan Amara, Maureen Gerlei, Carole Jeandel, Moulay Sahaka, Frédéric Carrière, Michel Linder
Marine liposomes are more resistant than triacylglycerol emulsion to lipolysis under gastric condition. They can protect LC-PUFA (EPA and DHA) and are a better gastric-stable delivery system for their intestinal absorption than TAG.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ergothioneine improves cognitive function by ameliorating mitochondrial damage and decreasing neuroinflammation in a D-galactose-induced aging model

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO02321H, Paper
Fangyang Chen, Botao Wang, Xin Sun, Yage Wang, Ruiyan Wang, Kaikai Li
EGT intervention significantly improved D-galactose induced oxidative stress, neuroinflammation, and mitochondrial function, resulting in the alleviation of memory injury.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Science for All | What are Trojan asteroids?

The Hindu’s weekly Science for All newsletter explains all things Science, without the jargon.




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Optimization of hair follicle spheroids for hair-on-a-chip

Biomater. Sci., 2024, 12,1693-1706
DOI: 10.1039/D3BM02012F, Paper
Subin Jeong, Hyeon-Min Nam, Gun Yong Sung
We report spheroids prepared by injecting LEF1 and Wnt1 into DPCs via transfection and then adding KCs and HUVECs. Through SEM, we observed a part extending outward from the TK and TKH surfaces, as indicated by white arrows.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A nanoparticle reinforced microporous methacrylated silk fibroin hydrogel to promote bone regeneration

Biomater. Sci., 2024, 12,2121-2135
DOI: 10.1039/D3BM01901B, Paper
Ruideng Wang, Xi He, Zhengyang Chen, Shilong Su, Jinwu Bai, Haifeng Liu, Fang Zhou
A photo-crosslinked nanocomposite hydrogel was prepared by incorporating an osteo-inductive inorganic nanoparticle for endogenous bone regeneration.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Neuroinflammatory response on a newly combinatorial cell–cell interaction chip

Biomater. Sci., 2024, 12,2096-2107
DOI: 10.1039/D4BM00125G, Paper
Yimeng Zhao, Xuefei Lv, Yu Chen, Chen Zhang, Di Zhou, Yulin Deng
Neuroinflammatory response on a novel combinatorial cell–cell interaction chip.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Engineering sulfated polysaccharides and silk fibroin based injectable IPN hydrogels with stiffening and growth factor presentation abilities for cartilage tissue engineering

Biomater. Sci., 2024, 12,2067-2085
DOI: 10.1039/D3BM01466E, Paper
Akansha Dixit, Aman Mahajan, Rakshita Saxena, Saptomee Chakraborty, Dhirendra S. Katti
In this study, we combined the β-sheet mediated self-stiffening ability of silk with growth factor presenting ability of sulphated carboxymethyl cellulose in an injectable interpenetrating network hydrogel for repair of articular cartilage defects.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Google announces new Android features at MWC 2024

The focus is on easier AI-assisted communication




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Endocrinology plays a vital role in diagnosing, managing and preventing lifestyle disorders like diabetes and thyroid, says Venkaiah Naidu





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Embroidery of Dreams: Deepika Khatri’s journey to Cannes

Designer Deepika Khatri made news when actor Rebecca Kunikowski wore her work on the red carpet. She talks about her life and how it brought her to Cannes




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Watch: Women artisans in Lucknow keep Chikankari embroidery alive




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Ace embroiderer Annie Titus Mammen crafts an independent line of embellished pashmina stoles

Chennai-based Annie Titus Mammen, who does embroidery for Chanel, Balenciaga and Louis Vuitton, has launched Tambour’s first Independent product line of embellished pashmina stoles in Delhi




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Google working on making Gemini take calls and send messages when Android phone is locked: Report

Currently, Gemini can reply to texts and take calls when a phone is locked, but only Google Assistant can do these tasks when the phone is unlocked




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OnePlus 13 launched with Snapdragon 8 Elite and Android 15. Price, specs

OnePlus 13 gets up to 24 GB RAM and up to 1 TB storage in its home market




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Zeroing in on home automation

After the hospitality sector, residential real estate has the maximum demand for automation that delivers higher levels of comfort, convenience and sustainability




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Infinix launches Android X3 smart TVs in India

The smart TVs will be available in 32-inch and 43-inch variants for pre-booking from March 12-16




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Android to get Apple’s MagSafe charger soon

The WPC expects the Qi2-enabled first batch of phones and wearables to roll out during the holiday season of 2023.




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2nd T20I PIX: SA stun India, Varun's heroics in vain

IMAGES from the second T20I in Gqeberha played between India and South Africa on Sunday




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PKL: U Mumba edge Yoddhas with last minute heroics

Ajit Chouhan and Rohit Raghav shone bright as U Mumba edged out UP Yoddhas 35-33 in a nail-biting contest to open the Noida leg of Pro Kabaddi League (PKL) at the Noida Indoor Stadium in Noida on Sunday.




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This Week in Apps: WWDC goes online, Android 11 delays, Facebook SDK turns into app kill switch

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.




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This Week in Apps: WWDC goes online, Android 11 delays, Facebook SDK turns into app kill switch

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.




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This Week in Apps: WWDC goes online, Android 11 delays, Facebook SDK turns into app kill switch

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.





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Trying Instagram on Android.. feels a bit slow maybe because my...



Trying Instagram on Android.. feels a bit slow maybe because my phone doesn’t have ICS (Taken with Instagram at St Peter’s College)




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ADAM10 and ADAM17 proteases mediate proinflammatory cytokine-induced and constitutive cleavage of endomucin from the endothelial surface [Membrane Biology]

Contact between inflammatory cells and endothelial cells (ECs) is a crucial step in vascular inflammation. Recently, we demonstrated that the cell-surface level of endomucin (EMCN), a heavily O-glycosylated single-transmembrane sialomucin, interferes with the interactions between inflammatory cells and ECs. We have also shown that, in response to an inflammatory stimulus, EMCN is cleared from the cell surface by an unknown mechanism. In this study, using adenovirus-mediated overexpression of a tagged EMCN in human umbilical vein ECs, we found that treatment with tumor necrosis factor α (TNF-α) or the strong oxidant pervanadate leads to loss of cell-surface EMCN and increases the levels of the C-terminal fragment of EMCN 3- to 4-fold. Furthermore, treatment with the broad-spectrum matrix metalloproteinase inhibitor batimastat (BB94) or inhibition of ADAM metallopeptidase domain 10 (ADAM10) and ADAM17 with two small-molecule inhibitors, GW280264X and GI254023X, or with siRNA significantly reduced basal and TNFα-induced cell-surface EMCN cleavage. Release of the C-terminal fragment of EMCN by TNF-α treatment was blocked by chemical inhibition of ADAM10 alone or in combination with ADAM17. These results indicate that cell-surface EMCN undergoes constitutive cleavage and that TNF-α treatment dramatically increases this cleavage, which is mediated predominantly by ADAM10 and ADAM17. As endothelial cell-surface EMCN attenuates leukocyte–EC interactions during inflammation, we propose that EMCN is a potential therapeutic target to manage vascular inflammation.




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[ Politics ] Open Question : Should Gregory and Travis McMichael be freed and given a medal of honor for their heroic actions of taking a dangerous thug of the streets?




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US-China rift roils global and India stocks

Extension of lockdown in India, albeit with some major relaxations, fails to enthuse investors.




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Assura On Steroids

In a recent post, I hinted at a significant performance improvement in Assura

Our R&D team focused on performance improvements in the 3.2 release, which was shipped last August.  Based on our suite of performance benchmarks, we achieved an overall 10x performance boost.  This comes from two fundamental improvements: an overall 3.5x boost in single processor performance, and an overall 2.8x performance boost from using four CPUs in a multiprocessor configuration. 

Your mileage may vary, of course.  Our test suite includes a variety of designs and processes - LVS testcases as well as DRC.  We typically noticed the most significant performance improvement on large designs that previously ran for many hours. 

This is a maintenance upgrade from the previous release, so there's no risk if you want to download the latest version just to kick the tires.  It will probably save you some time. 



  • ERC
  • Silicon Signoff and Verification
  • Assura







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Apex Legends Mobile Release Date News: iOS, Android soft launch set for 2020?

Apex Legends might finally be getting a mobile version, at least that's what EA's latest financial briefing seems to suggest




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This Week in Apps: WWDC goes online, Android 11 delays, Facebook SDK turns into app kill switch

We continue to look at how the coronavirus outbreak is impacting mobile apps; that big app crash caused by Facebook; new app releases from Facebook and Google; and Apple's plans to move WWDC online.




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Cyber Security Today – Zoom meeting job review scam, fake Labor Department email and a new Android threat

Zoom meeting job review scam, fake Labor Department email and a new Android threat. Welcome to Cyber Security Today. It’s Friday May 1st. I’m Howard Solomon, contributing reporter on cybersecurity for ITWorldCanada.com. To hear the podcast click on the arrow below: Videoconference provider Zoom has toughened its security by making it mandatory for users to…




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Mira Rajput tries her hand at embroidery with Misha, 'Little hands made the heart with a lot of excitement'

Shahid Kapoor and Mira Rajput tied the knot on July 7, 2015, in a private ceremony and since then their love has grown stronger. Mira is the daughter of Delhi-based businessman Vikramaditya Rajput and Bela Rajput. Shahid Kapoor and Mira Rajput became proud parents to baby girl Misha on August 26, 2016. Shahid Kapoor and Mira Rajput welcomed their second child, a baby boy on September 5, 2018, and the duo named their new-born Zain Kapoor.

Misha and Zain are one of the most adorable star kids of B-town. The cute little kiddos are the apple of everyone's eye. Just like other star babies, both the kids, particularly Misha has several fan clubs dedicated to her. Shahid and Mira often treat their fans with lovey-dovey pictures of their kids on Instagram.

During the coronavirus lockdown, Mira tried her hands at embroidery and even took some help from daughter Misha. Mira shared a picture of an embroidered heart and wrote, "Big love with my little love. With a hand drawn pattern and help on the turns, little hands made the heart with a lot of excitement and filled with a whole lot of love!" Take a look at the picture here:

The star wife keeps sharing snippets of her family quarantine time on her Instagram profile. She recently gave a shoutout to everyone for staying indoors. She wrote an elaborate open letter which read, "Love them. Hug them. Ask them how they feel and let them cry if they're not okay. Kiss them. Paint with them and let their clothes and the walls get dirty. Watch their favourite cartoon with them. Snuggle up with them. Give them extra ketchup if they ask for it that day. And when you’re tired after doing the dishes and cooking dinner and they say “Mumma can you play with me” remember this time isn’t forever. Little hands. Big hearts Love them."

 
 
 
View this post on Instagram

A post shared by Mira Rajput Kapoor (@mira.kapoor) onApr 29, 2020 at 9:52am PDT

On the work front, Shahid Kapoor's last film, Kabir Singh, did excellently at the box office. The Sandeep Reddy Vanga directorial was the story of a brilliant doctor who takes the self-destructive path when the love of his life is forced to marry another man. It earned over Rs 250 crore and became one of the highest grosser of 2019.

As of now, Shahid has signed the Hindi remake of the Telugu film Jersey, which is the story of a cricketer and how he battles the politics within the game and his inner demons. The film is all set to release on August 28, 2020.

Catch up on all the latest entertainment news and gossip here. Also, download the new mid-day Android and iOS apps.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news




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New scoping document on in vitro and ex vivo assays for the identification of modulators of thyroid hormone signalling

This scoping document brings forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, and provide recommendations for their further development/use, and also, to identify aspects of the thyroid signalling pathway that are not covered and would require further attention




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OECD encourages the development of non-animal test methods for the detection of thyroid disrupters

The OECD Advisory Group on Endocrine Disrupters Testing and Assessment met on 16-17 October 2014 in Paris to discuss the development and update of Test Guidelines and related documents for endocrine disrupters testing and assessment.