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The fabrication of the photothermal antibacterial platform for bacterial infectious skin wound healing: A review

By pubs.rsc.org
Published On ::

Mol. Syst. Des. Eng., 2024, Accepted Manuscript
DOI: 10.1039/D4ME00010B, Review Article
Mei Han, Wenjing Sun, Yi Chen, Hongbin Li
Antibiotics are currently the main strategy to treat bacterial infections, but they can cause bacterial resistance, and it is urgent to solve this problem. The emergence of photothermal therapy provides...
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Free Prototype Program

By bocoup.com
Published On :: Tue, 05 Mar 2024 16:20:03 +0000

Bocoup is trying something new! We’re launching an opportunity to build a free prototype for you or your organization. We want to ensure that funding is not a barrier to entry to get new ideas out into the world, and we believe prototypes can open doors. Application Information Application link: https://freeprototype.bocoup.com Application deadline: Rolling until […]


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Nanomaterial-mediated photothermal therapy modulates tumor-associated macrophages: applications in cancer therapy

By pubs.rsc.org
Published On ::

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01928H, Review Article
Yan Li, Yuhao Si, Heng Yin
Nanomaterials for modulating tumor-associated macrophages in photothermal therapy.
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Ti-based MOF nanosheets as a mass spectrometry imaging matrix for low molecular weight compounds to reveal the spatiotemporal content changes of hepatotoxic components during the processing of Polygonum multiflorum

By pubs.rsc.org
Published On ::

Analyst, 2024, Advance Article
DOI: 10.1039/D4AN00964A, Paper
Feng-yan Kuang, De-jun Hu, Lu Wang, Fei Chen, Guang-ping Lv
The selection of the matrix is crucial for matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI).
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Photothermal properties of MXenes and sterilization of MRSA by Nb2C/Gel with a low power NIR-II laser

By pubs.rsc.org
Published On ::

New J. Chem., 2024, 48,7045-7051
DOI: 10.1039/D4NJ00245H, Paper
Yekai Zheng, Xinyi Fu, Li Jiang, Denghao Li, Weidan Zhao, Mi Liu, Jiali Liu, Shangzhong Jin, Yan Zhou
A comparative study on the photothermal properties of MXenes (Ti3C2, V2C and Nb2C) and MXene/Gels (Ti3C2/Gel, V2C/Gel and Nb2C/Gel). The fast and efficient sterilization of MRSA was achieved using Nb2C/Gel at low laser power.
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A colorimetric and photothermal dual-mode immunobiosensor for chloramphenicol based on the β-NiOOH nanozyme-3,3',5,5'-tetramethylbenzidine system

By pubs.rsc.org
Published On ::

New J. Chem., 2024, 48,7340-7346
DOI: 10.1039/D4NJ00648H, Paper
Yuxing Lian, Mengqin Zheng, Suhua Li, Wenqiang Lai, Dianping Tang, Youxiu Lin
A colorimetric and photothermal dual-mode detection method based on β-NiOOH nanozyme-3,3',5,5'-tetramethylbenzidine system was established for chloramphenicol content in fruit juice.
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Influence of the secondary ligand, phenanthroline, on the antioxidant and pro-oxidant and cytotoxic effects of the oxidovanadium(IV)/naringin complex

By pubs.rsc.org
Published On ::

New J. Chem., 2024, Advance Article
DOI: 10.1039/D4NJ00655K, Paper
Andrés G. Restrepo, Angel L. Huamani, Alexandra Velásquez Bravo, Pablo J. González, Luciana G. Naso, Evelina G. Ferrer, Patricia A. M. Williams
Replacement of phen in [VO(Narg)2] induces greater π electronic delocalization, thus improving antioxidant action. However, due to its lipophilic character, cellular uptake of V is increased, leading to enhanced pro-oxidant and anticancer effects.
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For the TEAtotaller

By www.thehindu.com
Published On :: Tue, 15 Nov 2016 16:04:40 +0530

Tea is just more than a few leaves in hot water. Startup, Teabox, which ships Indian and Nepalese tea to over 95 countries, has shown what a good cup of the brew can do


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The pulmonary effects of nickel-containing nanoparticles: cytotoxicity, genotoxicity, carcinogenicity, and their underlying mechanisms

By pubs.rsc.org
Published On ::

Environ. Sci.: Nano, 2024, Advance Article
DOI: 10.1039/D3EN00929G, Critical Review
Yiqun Mo, Yue Zhang, Qunwei Zhang
This review summarized the cytotoxic, genotoxic, and carcinogenic effects of Ni-containing NPs on humans, lung cells in vitro, and rodent lungs in vivo, and the underlying mechanisms. Their extra-pulmonary effects were also briefly mentioned.
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New 8-hydroxy quinoline-polycyclic aromatic hydrocarbon (PAH) conjugates and their sulfonated derivatives: effects of sulfonation and PAH size on their structural, supramolecular and cytotoxic properties

By pubs.rsc.org
Published On ::

CrystEngComm, 2024, Advance Article
DOI: 10.1039/D4CE00105B, Paper
Suman Sehlangia, Surbhi Dogra, Prosenjit Mondal, Chullikkattil P. Pradeep
The ring size of polycyclic aromatic hydrocarbons (PAHs) and sulfonation affect the supramolecular interactions and cytotoxic properties of a new series of 8-hydroxy quinoline-PAH conjugates.
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Micro & small enterprises corner 55% of total orders placed on GeM portal

By www.thehindubusinessline.com
Published On :: Wed, 11 Jan 2023 13:53:41 +0530

Procurement of goods and services from GeM has crossed ₹1-lakh cr so far this fiscal on account of an increase in buying activities by different ministries and departments


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Chemoenzymatic total synthesis of rotigotine via IRED-catalyzed reductive amination

By pubs.rsc.org
Published On ::

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00072B, Communication
Dongyu Tang, Yaqing Ma, Jinping Bao, Shushan Gao, Shuli Man, Chengsen Cui
An engineered imine reductase (IRED) was developed specifically for 2-tetralone substrate, and utilized in the total synthesis of rotigotine.
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Asymmetric total synthesis of humulane sesquiterpenoids alashanoids B, C, E, and F and 2,9-humuladien-6-ol-8-one

By pubs.rsc.org
Published On ::

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00393D, Paper
Rasmita Barik, Samik Nanda
Naturally occurring sesquiterpenes having humulane frameworks are structurally intriguing and possess significant biological profiles.
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Total synthesis of diplofuranone A and diapolic acid A

By pubs.rsc.org
Published On ::

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00433G, Communication
Dattatraya H. Dethe, Vimlesh Kumar, Nagabhushana C. Beeralingappa
The first and concise syntheses of the anticancer agent diplofuranone A and the fatty acid-derived metabolite diapolic acid A have been demonstrated using easily accessible and commercially available starting materials.
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N-Functionalization of beta-aminophosphonates; Cytotoxic effect of the new derivatives

By pubs.rsc.org
Published On ::

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00243A, Paper
György Keglevich, Petra Regina Varga, Emőke Dinnyési, Zsuzsanna Szalai, Szilvia Bősze, Rita Oláhné Szabó, Laszlo Drahos, Konstantin Karaghiosoff
Beta-Aminophosponates obtained by the Michael addition of primary amines to the double bond of diethyl vinylphosphonate proved to be suitable starting materials (amine components) in the Kabachnik–Fields reaction with formaldehyde...
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Total worldwide PC shipments increased 53.1 per cent in Q1 2021: Report

By www.thehindubusinessline.com
Published On :: Thu, 06 May 2021 12:30:00 +0530

Revival led by strong growth in Chromebooks and tablets


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  • Computers & Laptops
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(WO + ICG)@PLGA@lipid/plasmid DNA nanocomplexes as core–shell vectors for synergistic genetic/photothermal therapy

By pubs.rsc.org
Published On ::

Mater. Chem. Front., 2024, 8,3747-3757
DOI: 10.1039/D4QM00330F, Research Article
Yang Bai, Guoqing Feng, Qingbin Yang, Tingting Hua, Bowen Li, Hao-Lin Guo, Yuan Liu, Qing Yuan, Niansong Qian, Bin Zheng
(WO + ICG)@PLGA@PL could not only achieve a synergistic therapy effect of gene delivery and photothermal effect but also effectively inhibit tumor growth.
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Stephen Fitzpatrick: Zero Carbon Won't Be Easy: Our Energy Model Needs A Total Overhaul

By www.wired.com
Published On :: Wed, 27 Mar 2019 06:37:27 +0000

We're not winning the fight against climate change, as the 2018 IPCC report makes incontrovertible. What does energy in a zero carbon world look like? Well, we have a lot of challenges ahead of us: companies can't tackle this work on their own, which means embracing collaboration, and changing the energy model. Stephen Fitzpatrick is the CEO and founder of OVO Energy, a UK energy provider which has launched the world’s first commercially available electric-vehicle-to-grid charger in partnership with Nissan. ABOUT WIRED SMARTER Experts and business leaders from the worlds of Energy, Money and Retail gathered at Kings Place, London, for WIRED Smarter on October 9, 2018. Discover some of the fascinating insights from speakers here: http://wired.uk/V29vMg ABOUT WIRED EVENTS WIRED events shine a spotlight on the innovators, inventors and entrepreneurs who are changing our world for the better. Explore this channel for videos showing on-stage talks, behind-the-scenes action, exclusive interviews and performances from our roster of events. Join us as we uncover the most relevant, up-and-coming trends and meet the people building the future. ABOUT WIRED WIRED brings you the future as it happens - the people, the trends, the big ideas that will change our lives. An award-winning printed monthly and online publication. WIRED is an agenda-setting magazine offering brain food on a wide range of topics, from science, technology and business to pop-culture and politics. CONNECT WITH WIRED Web: http://po.st/WiredVideo Twitter: http://po.st/TwitterWired Facebook: http://po.st/FacebookWired Google+: http://po.st/GoogleWired Instagram: http://po.st/InstagramWired Magazine: http://po.st/MagazineWired Newsletter: http://po.st/NewslettersWired


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Tech Support - The Best of Tech Support: Ken Jeong, Bill Nye, Nicole Stott and More

By www.wired.com
Published On :: Thu, 26 Dec 2019 17:00:00 +0000

As 2019 comes to a close, we take a look back at some of the most interesting questions asked on WIRED Tech Support. Ken Jeong, Nicole Stott, Amanda "Malware Unicorn" Rousseau, Anil Seth, Bill Nye and Jill Tarter, answer a wide variety of questions ranging from extraterrestrials to flu shots.


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Every Prototype that Led to a Realistic Prosthetic Arm

By www.wired.com
Published On :: Wed, 10 Nov 2021 17:00:00 +0000

Since the early 2000s, private companies, governments, and research labs have been developing prosthesis that are a lot more advanced than previous designs. WIRED talked with Easton LaChapelle, founder and CEO of Unlimited Tomorrow, to understand how he designed, tested, and adopted his prosthetic arm.The movie GENERATION IMPACT: THE INVENTOR, follows 25-year old innovator Easton LaChappelle, who developed the world’s lightest weight and most affordable bionic limb. GENERATION IMPACT: THE INVENTOR, can be viewed on HP.com’s digital hub, the Garage (hp.com/generation-impact) and YouTube


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Every Prototype to Make a Humanoid Robot

By www.wired.com
Published On :: Tue, 22 Feb 2022 17:00:00 +0000

This team of designers and roboticist think they've figured out how to combat the uncanny valley. WIRED talked with Will Jackson, founder and CEO of Engineered Arts to understand how they design, prototype, and test their humanoid robots.Thanks to the team at Engineered Arts for the tour https://www.engineeredarts.co.uk/


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Recyclable microcellular rubber foams with superior photothermal performance via constructing Fe3+ heterodentate coordination between epoxidized natural rubber and polyaniline

By pubs.rsc.org
Published On ::

J. Mater. Chem. A, 2024, 12,30486-30497
DOI: 10.1039/D4TA06543C, Paper
Jingyi Zhu, Yukun Chen, Patrick C. Lee, Shuidong Zhang
Developing recyclable microcellular rubber foams with excellent photothermal conversion ability can reduce resource waste and harvest solar energy to alleviate environmental pollution and the energy crisis simultaneously.
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Tailoring the electrocatalytic properties of novel microwave synthesized CuNd(2−x)GdxO4 nanoparticles for efficient total water splitting in alkaline media

By pubs.rsc.org
Published On ::

J. Mater. Chem. A, 2024, 12,30850-30861
DOI: 10.1039/D4TA05919K, Paper
Anto Priyanka E, Sreenivasan Nagappan, J. Judith Vijaya, Angappan Sankaramahalingam, Subrata Kundu
CuNd(2−x)GdxO4 nanoparticles synthesized via microwave method as efficient OER and HER catalysts require low overpotentials exhibiting remarkable stability. Gd doping enhances charge transfer leading to optimized electrocatalysis.
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For a short, dreamy break, Sri Lanka’s Bentota makes for a perfect getaway

By www.thehindu.com
Published On :: Tue, 09 Apr 2024 16:29:30 +0530

Believed to have been named after a mythical demon, ‘Bem’ who ruled the river banks ‘tota’, a portion of this coastal town, once a fishing/farming village, and now popular with tourists, is sandwiched between the river and the sea


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A new era of cancer phototherapy: mechanisms and applications

By pubs.rsc.org
Published On ::

Chem. Soc. Rev., 2024, Advance Article
DOI: 10.1039/D4CS00708E, Review Article
Yuanwei Wang, Ke Ma, Miaomiao Kang, Dingyuan Yan, Niu Niu, Saisai Yan, Panpan Sun, Luzhi Zhang, Lijie Sun, Dong Wang, Hui Tan, Ben Zhong Tang
The past decades have witnessed great strides in phototherapy as an experimental option or regulation-approved treatment in numerous cancer indications.
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The Total Risk Premium Puzzle [electronic journal].

By encore.st-andrews.ac.uk
Published On ::

National Bureau of Economic Research


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Pricing Carbon Under Economic and Climactic Risks: Leading-Order Results from Asymptotic Analysis [electronic journal].

By encore.st-andrews.ac.uk
Published On ::


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CDs "inserted" abundant FeB based electrode via "local photothermal effect" strategy toward efficient overall seawater splitting

By pubs.rsc.org
Published On ::

Inorg. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QI00415A, Research Article
Shiheng Liang, Liugang Wu, Yiming Wang, Yuqi Shao, Hongyuan Song, Ziliang Chen, Weiju Hao
Construction of high-efficiency, long-stable catalytic electrodes for hydrogen by seawater splitting is a huge challenge in the field of green hydrogen. Herein, a matrix-type titanium dioxide nanorod (Ti/TiO2) is constructed...
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Substituent effect in determining the total structure of an all-alkynyl-protected Ag98 nanocluster for methanol tolerant oxygen reduction reaction

By pubs.rsc.org
Published On ::

Chem. Sci., 2024, 15,18161-18169
DOI: 10.1039/D4SC04318A, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xiaoqin Cui, Xuehuan Zhang, Ting Li, Sheng Zhu, Gaoyi Han, Huan Li
A sterically demanding ortho-CF3 substituent defines not only the arrangement of ligands on a Ag98(2-CF3PhCC)48Cl4 nanocluster (Ag98) but also the inter-cluster interactions. Ag98 shows excellent methanol tolerance in the oxygen reduction reaction.
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Andhra Pradesh Chief Minister lays foundation for three renewable energy projects with a total capacity of 5,314MW

By www.thehindu.com
Published On :: Wed, 23 Aug 2023 17:02:47 +0530

A JV pact was also signed by the State power corporation and the National Hydropower Corporation for two pumped storage hydropower projects


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Near-infrared responsive gold nanorods for highly sensitive colorimetric and photothermal lateral flow immuno-detection of SARS-CoV-2

By pubs.rsc.org
Published On ::

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00347K, Paper
Xiaohui Liu, Jingwen Li, Kun Wang, Xiang Li, Shenming Wang, Gengchen Guo, Qiaowen Zheng, Maosheng Zhang, Jingbin Zeng
We developed a colorimetric and photothermal dual-mode LFIA platform for sensitive and selective SARS-CoV-2 N protein detection based on gold nanorods.
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Field method for preservation of total mercury in waters, including those associated with artisanal scale gold mining

By pubs.rsc.org
Published On ::

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02216A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
David C. P. King, Michael J. Watts, Elliott M. Hamilton, Robert J. G. Mortimer, Mike Coffey, Odipo Osano, Maureene Auma Ondayo, Marcello Di Bonito
A method was developed for sampling and preserving total Hg from water samples, recovering >75% Hg over 4 weeks of storage. The method was assessed using water samples at artisanal gold mining sites in Kenya.
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Synthesis and cytotoxic activity of madecassic acid–silybin conjugate compounds in liver cancer cells

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, 15,3418-3432
DOI: 10.1039/D4MD00170B, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Chien Van Tran, Thao Thi Phuong Tran, Anh The Nguyen, Loc Van Tran, Ninh Thi Pham, Luu Thi Nguyen, Dung Thi Nguyen, Michelle D. Garrett, Nga Thi Nguyen, Thao Thi Do, Christopher J. Serpell, Sung Van Tran
Madecassic acid and silybin have been conjoined to produce hybrid compounds with improved and different activity against liver cancer cells.
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A comprehensive apoptotic assessment of niloticin in cervical cancer cells: a tirucallane-type triterpenoid from Aphanamixis polystachya (Wall.) Parker

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, 15,3444-3459
DOI: 10.1039/D4MD00318G, Research Article
Anuja Gracy Joseph, Mohanan Biji, Vishnu Priya Murali, Daisy R. Sherin, Alisha Valsan, Vimalkumar P. Sukumaran, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar Maiti
Niloticin, a triterpenoid from Aphanamixis polystachya, induces apoptosis in HeLa cells which is primarily validated through in silico analysis and subsequently in vitro apoptotic evaluation by modulating the apoptotic proteins.
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Exploring apoptotic induction of malabaricone A in triple-negative breast cancer cells: an acylphenol phyto-entity isolated from the fruit rind of Myristica malabarica Lam.

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, 15,3558-3575
DOI: 10.1039/D4MD00391H, Research Article
Pothiyil S. Vimalkumar, Neethu Sivadas, Vishnu Priya Murali, Daisy R. Sherin, Madhukrishnan Murali, Anuja Gracy Joseph, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar Maiti
Malabaricone A isolated from Myristica malabarica induces apoptosis in triple-negative breast cancer cells through intrinsic and extrinsic pathways, which is validated through in vitro and in silico studies and resembles a potent phyto-entity.
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Exploring 7β-amino-6-nitrocholestens as COVID-19 antivirals: in silico, synthesis, evaluation, and integration of artificial intelligence (AI) in drug design: assessing the cytotoxicity and antioxidant activity of 3β-acetoxynitrocholestane

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00257A, Research Article
Shahabuddin, Uzma, Mohammad Azam, Mehtab Parveen, Nurul Huda Abd Kadir, Kim Min, Mahboob Alam
In light of the ongoing pandemic caused by SARS-CoV-2, effective and clinically translatable treatments are desperately needed for COVID-19 and its emerging variants.
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Modulating polybasic character of galactose-based glycosylated antitumor ether lipids for enhanced cytotoxic response

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00662C, Research Article
Rajat Arora, Ayan Mukherjee, Gilbert Arthur, Mark W. Nachtigal, Frank Schweizer
We describe the multi-step synthesis of different dibasic and tribasic galactosamine-based glycosylated antitumor ether lipids (GAELs) and their cytotoxic response in comparison to doxorubicin and cisplatin.
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Amides of moronic acid and morolic acid with the tripeptides MAG and GAM targeting antimicrobial, antiviral and cytotoxic effects

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00742E, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Uladzimir Bildziukevich, Lucie Cerna, Jana Trylčová, Marie Kvasnicova, Lucie Rárová, David Šaman, Petra Lovecká, Jan Weber, Zdenek Wimmer
A series of amides of the selected plant triterpenoids, moronic acid and morolic acid, with the tripeptides MAG and GAM was designed and synthesized. Two required tripeptides 5 and 10...
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meso-Substituted AB3-type phenothiazinyl porphyrins and their indium and zinc complexes photosensitising properties, cytotoxicity and phototoxicity on ovarian cancer cells

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00601A, Research Article
Open Access
Brém Balázs, Bianca Stoean (Vasile), Éva Molnár, Eva Fischer-Fodor, Ovidiu Bălăcescu, Raluca Borlan, Monica Focsan, Adriana Grozav, Patriciu Achimaş-Cadariu, Emese Gál, Luiza Gaina
New meso-substituted AB3-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, respectively.
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Light enhanced cytotoxicity and antitumoral effect of a ruthenium-based photosensitizer inspired from natural alkaloids

By pubs.rsc.org
Published On ::

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00600C, Research Article
Open Access
Gennaro Sanità, Maria Laura Alfieri, Barbara Carrese, Serena Damian, Vincenza Mele, Gaetano Calì, Brigida Silvestri, Sebastiano Marra, Susan Mohammadi, Giuseppina Luciani, Paola Manini, Annalisa Lamberti
Biological assays carried out on melanoma and breast cancer cells highlighted the role of light in boosting the cytotoxic effect of a ruthenium complex featuring a dihydroisoquinoline ligand suggesting applications in photodynamic therapy.
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568: Display Contents, Passkeys Follow Up, Yellow Fade Technique, and TOTK Talk

By shoptalkshow.com
Published On :: Mon, 05 Jun 2023 19:53:09 +0000

Macho Man Randy Standards stops by for a quick chat, Passkeys follow up, discussing the safety of Display: contents, the yellow fade technique, how hot CSS is right now (so hot), and a check in on how everyone's doing with Tears of the Kingdom.


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620: Cloudflare #HotDrama, Auth, and Prototyping Thoughts

By shoptalkshow.com
Published On :: Mon, 17 Jun 2024 08:27:24 +0000

Show DescriptionWe dive a bit deeper into the Cloudflare drama of the past couple of weeks, Instagram ads vs Cara art, what to do about Auth in your app, pre-negging any sponsorships, prototyping and feedback on projects, and ideas for future topics. Listen on Website →Links Cloudflare took down our website after trying to force […]


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Problems and theorems in classical set theory [electronic resource] / Peter Komjath, Vilmos Totik

By darius.uleth.ca
Published On ::

New York ; Berlin : Springer, 2006


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Synergy of prediction rule and total synthesis in solving the stereochemical puzzle of eucalactam B

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01777C, Research Article
Chenqi Wang, Junyang Liu, Tao Ye
The absolute configurations of the fungal-derived reduced polyketide eucalactam B were initially predicted using the “Biochemistry-based rule” and later confirmed through its first successful total synthesis.
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Towards the total synthesis of mandelalide B: construction of the tetrahydrofuran/α-hydroxyl lactone fragment

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6353-6357
DOI: 10.1039/D4QO01433B, Research Article
Jia-Lei Yan, Jie Yu, Yingying Cheng, Mingze Yang, Zhengshuang Xu, Tao Ye
A stereocontrolled synthesis of the tetrahydrofuran/α-hydroxy lactone fragment of mandelalide B has been accomplished. The synthesis features a Horner-Wadsworth-Emmons fragment assembly strategy and a highly stereospecific iodine-induced cyclization.
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Total synthesis of spiro Ganoderma meroterpenoids spiroapplanatumines B, D, F, and H

By pubs.rsc.org
Published On ::

Org. Chem. Front., 2024, 11,6333-6339
DOI: 10.1039/D4QO01147C, Research Article
Jia-Hao Zhang, Wen-Cai Luo, Wen-Tao Chen, Yu-Tao He, Ya-Jian Hu
The first total synthesis of spiroapplanatumines B, D, F, and H as well as the possibly undiscovered natural product spiroapplanatumine R has been achieved.
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Newly synthesized sulfonamide derivatives explored for DNA binding, enzyme inhibitory, and cytotoxicity activities: a mixed computational and experimental analyses

By pubs.rsc.org
Published On ::

RSC Adv., 2024, 14,35047-35063
DOI: 10.1039/D4RA06412G, Paper
Open Access
Nasima Arshad, Yasir Mehmood, Hammad Ismail, Fouzia Perveen, Aneela Javed, Pervaiz Ali Channar, Aamer Saeed, Sadia Naseem, Fatima Naseer
This work reports synthesis, characterization, DNA, enzyme binding and cytotoxicity activity of three 4-((3-arylthiazolo[3,4-d]isoxazol-5-yl)amino)benzene sulfonamide derivatives with a thaizaole(3,4-d)isoxazole-based fused ring heterocyclic system.
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Check out India's lowest totals in Test cricket

By www.rediff.com
Published On :: Thu, 17 Oct 2024 15:41:36 +0530

India's overall lowest, however, was recorded four years ago against Australia when they were shot out for a mere 36 at Adelaide.


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Tottenham beat 10-man Manchester United to up pressure on Ten Hag

By www.thehindu.com
Published On :: Mon, 30 Sep 2024 11:50:00 +0530

Tottenham should have added to their lead long before United were reduced to 10 men when captain Fernandes was shown a straight red card on 42 minutes.


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Ten Hag future up in the air after Man United draws at Villa; Tottenham collapses in 3-2 loss

By www.thehindu.com
Published On :: Mon, 07 Oct 2024 02:35:16 +0530

United heads into the two-week international break on a five-match winless run in all competitions and languishing in 14th place in the league, having won just two of its opening seven games this campaign


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