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Quantifying the polar skyrmion motion barrier in an oxide heterostructure

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03686G, Paper
Lizhe Hu, Yuhui Huang, Yong Jun Wu, Zijian Hong
Exotic polar topologies such as polar skyrmions have been widely observed in the ferroelectric superlattice system. The dynamic motion of the polar skyrmion under external forces holds promise for applications...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Nanotechnology-based delivery of therapeutics through the intranasal pathway and the blood–brain barrier for Alzheimer's disease treatment

Biomater. Sci., 2024, 12,2007-2018
DOI: 10.1039/D3BM02003G, Review Article
Mark-Jefferson Buer Boyetey, Yonghyun Choi, Hee-Young Lee, Jonghoon Choi
Drugs for Alzheimer's disease (AD) fail to exhibit efficacy in clinical trials for a number of reasons, a major one being blood–brain barrier (BBB) permeability.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Pregnancy is still a barrier in accessing employment

The legislature must recognise that medical certifications, physical tests, and arbitrary disqualification criteria are used to deny pregnant persons their employment opportunities




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The Hugo Barra factor in Xiaomi




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K. Barry Sharpless named 2019 Priestley Medalist

Scripps Research Institute chemist honored for inventing catalytic, asymmetric oxidation methods and pioneering click chemistry




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Ural shipments to India rise 10% in October as refinery maintenance spares more barrels

According to energy intelligence firm Vortexa, India’s crude oil imports from Russia were largely flat on a monthly and annual basis at 1.45 million barrels per day (mb/d) in October 2024, according to energy intelligence firm Vortexa




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Against All Odds: Polio no barrier for Abhay Todkar, who has stepped up water conservation efforts in 60 villages




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'What life was all about for him was family': Remembering Dennis Barrett, who had COVID-19

Dennis Barrett, an east Indianapolis native, died of the coronavirus in March. His wife remembers him as a devoted father and ambitious entrepreneur.

       





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Polar vortex shatters single-day records in Barrie

Many in the region had to dust off their snow shovels for at least one more dig out on Saturday morning after a polar vortex blasted parts of the province, catching many off guard.




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Professor Who Mocked Barron Trump During Senate Hearings Gets Censorship Position at Facebook

The following article, Professor Who Mocked Barron Trump During Senate Hearings Gets Censorship Position at Facebook, was first published on 100PercentFedUp.com.

Facebook just announced a 20 person board of oversight that will assist with content moderation. One of the people selected for the board, a professor at Stanford Law School, was announced as a member of the board and is raising eyebrows because of her snarky comment about Barron Trump during Senate Impeachment Hearings. Pamela Karlan, […]

Continue reading: Professor Who Mocked Barron Trump During Senate Hearings Gets Censorship Position at Facebook ...




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‘Not a Bonafide Counterintelligence Investigation’: Barr Slams Comey’s Handling of Flynn Probe

Attorney General Bill Barr explained that the FBI did not conduct “a bonafide counterintelligence investigation” in the case that led former Trump national security adviser Michael Flynn to plead guilty to federal investigators in 2017.Barr, speaking in an exclusive interview with CBS News after the Justice Department dropped its case against Flynn on Thursday, said that his review of the case found Bureau investigators laid “a perjury trap” for Flynn in a January 2017 White House interview.“They didn’t warn him, the way that would usually be required by the Department, they bypassed the Justice Department, they bypassed the protocols at the White House, and so forth,” Barr stated. “These were things that persuaded me that there was not a legitimate counterintelligence investigation.”Former FBI director James Comey admitted in a December 2018 interview that he “sent” the agents to interview Flynn, adding that it was “something I probably wouldn’t have done or maybe gotten away with in a more organized administration.”In its Thursday court filing, the Justice Department explained that it was “not persuaded” that Flynn’s interview, which led to his guilty plea for lying to FBI agents Peter Strzok and Joe Pientka, had proper predication and was materially relevant.Comey tweeted his disappointment, following the decision, saying "the DOJ has lost its way."> The DOJ has lost its way. But, career people: please stay because America needs you. The country is hungry for honest, competent leadership.> > -- James Comey (@Comey) May 7, 2020Barr pointed to recently-released information that showed the FBI moved to close its surveillance of Flynn after finding “no derogatory information” about the retired general’s contacts with Russians, only for Strzok to keep the case open, leading to the eventual interview.“They were closing the investigation, in December [2016], they started that process and on January 4, they were closing it. When they heard about the phone call, which the FBI had the transcripts to — there was no question as to what was discussed, the FBI knew exactly what was discussed — and General Flynn, being the former director of the DIA, said to them, ‘you listen to everything, you know what was said,’” Barr explained.“So there’s no mystery about the call, but they initially tried some theories of how could open another investigation, which didn’t fly, and then they found out that they had not technically closed the earlier investigation, and they kept it open for the expressed purpose of trying to catch — lay a perjury trap — for General Flynn,” he added. A different filing released last week showed handwritten notes from an FBI official that questioned if the goal of Flynn’s White House interview was “to get him to lie, so we can prosecute him or get him fired.”Barr also did not comment on whether those that sought to entrap Flynn would face criminal charges, pointing to U.S. Attorney John Durham’s probe into the origins of the Trump-Russia investigation and saying his team was “in the middle” of “looking at the whole pattern of conduct.”“I’m going to wait until all the evidence is [in], and I get their recommendations as to what they found and how serious it is. But, if we were to find wrongdoing, in the sense of any criminal act, obviously we would follow through on that,” Barr said. “But again, just because something may even stink to high heaven, and appear to everyone to be bad, we still have to apply the right standard and be convinced that there is a violation of a criminal statute and that we can prove it beyond a reasonable doubt. The same standard applies to everybody.”





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LEP Workers & Access to Workforce Services: Perspectives on Current Barriers to Access and Prospects for Improvements Under WIA Reauthorization

In this webinar, experts discuss barriers immigrant and LEP individuals face in accessing the WIA system, how a revitalized WIA could address these barriers, and the extent to which the current Senate Health, Education, Labor, and Pensions (HELP) Committee's WIA reauthorization proposal addresses these barriers.




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Overcoming WIOA’s Barriers to Immigrant and Refugee Adult Learners

A webinar examining aspects of the implementation at state and local levels of the federal Workforce Innovation and Opportunity Act (WIOA) that may limit immigrant integration, along with a discussion on strategies that may help ensure more equitable access for immigrants and refugees to services provided under the law.  




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HR e-briefing 430 - The vetting and barring scheme - the facts

The recruitment practices of many employers stand to be significantly affected by the introduction, from October 12 this year, of the new vetting and barring scheme for those working with children or vulnerable adults. The scheme will apply in Engla...




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Newmark Group, Inc. (NMRK) CEO Barry Gosin on Q1 2020 Results - Earnings Call Transcript




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‘#BlackAF’ Creator Kenya Barris Adds Another L.A. Home to Packed Portfolio

Nearly two years ago, “Black-ish” creator Kenya Barris signed a $100 million overall deal with Netflix, placing him among a rarefied list of creators — which also includes Shonda Rhimes, Ryan Murphy and “Game of Thrones” showrunners David Benioff and DB Weiss — able to command a nine-figure production pact with one of the world’s […]





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Storm builds around Barr over Flynn case...


Storm builds around Barr over Flynn case...


(First column, 6th story, link)





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‘BRUH’ Co-Star Barry Brewer Talks About Brotherhood



The bonds between Black men can be complicated.




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Barrichello impresses Williams' Sam Michael

Williams' technical director Sam Michael has said he is impressed with Rubens Barrichello after working alongside the Brazilian veteran for his first two races of the season




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Barrichello defends steering-wheel claims

Rubens Barrichello has denied suggestions he recklessly endangered his Formula One rivals at the Monaco Grand Prix




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Loose manhole cover caused Barrichello's crash

A loose manhole cover was responsible for causing Rubens Barrichello's spectacular accident in the Monaco Grand Prix




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Overcoming barriers to international investment in clean energy, Investment Insights - June 2015

Protectionism and local content requirements are holding back investment in clean energy and thus undermining the fight against climate change. This Investment Insights puts forward policy options for mobilising investment in clean energy and restoring order and confidence in international markets.




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Legal and social barriers holding back women’s empowerment in Middle East and North Africa

Women in the Middle East and North Africa are better educated and better skilled than ever, yet legal and social barriers mean the share of them in work is still the lowest in the world. Bringing family and labour laws into line with gender goals would enable more women to enter employment and would make MENA economies more competitive and inclusive, according to a new OECD report.




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Matt Damon and wife Luciana Barroso get the VIP treatment at Brisbane Airport

He's a Hollywood A-lister, so most people would expect Matt Damon to travel in style everywhere he goes.




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Frank Warren warns 53-year-old Mike Tyson would be 'embarrassed' in return to the ring

Mike Tyson's potential return to the ring will end in 'embarrassment', promoter Frank Warren has warned. A video of Tyson hitting the pads with trademark tenacity went viral last week




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Migrant workers jump barricades, set off on foot to native places

Additional police forces deployed at Polavarm; situation under control, says police




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Barring essential services, lockdown in Punjab till March 31




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3D domain swapping in the TIM barrel of the α subunit of Streptococcus pneumoniae tryptophan synthase

Tryptophan synthase catalyzes the last two steps of tryptophan biosynthesis in plants, fungi and bacteria. It consists of two protein chains, designated α and β, encoded by trpA and trpB genes, that function as an αββα complex. Structural and functional features of tryptophan synthase have been extensively studied, explaining the roles of individual residues in the two active sites in catalysis and allosteric regulation. TrpA serves as a model for protein-folding studies. In 1969, Jackson and Yanofsky observed that the typically monomeric TrpA forms a small population of dimers. Dimerization was postulated to take place through an exchange of structural elements of the monomeric chains, a phenomenon later termed 3D domain swapping. The structural details of the TrpA dimer have remained unknown. Here, the crystal structure of the Streptococcus pneumoniae TrpA homodimer is reported, demonstrating 3D domain swapping in a TIM-barrel fold for the first time. The N-terminal domain comprising the H0–S1–H1–S2 elements is exchanged, while the hinge region corresponds to loop L2 linking strand S2 to helix H2'. The structural elements S2 and L2 carry the catalytic residues Glu52 and Asp63. As the S2 element is part of the swapped domain, the architecture of the catalytic apparatus in the dimer is recreated from two protein chains. The homodimer interface overlaps with the α–β interface of the tryptophan synthase αββα heterotetramer, suggesting that the 3D domain-swapped dimer cannot form a complex with the β subunit. In the crystal, the dimers assemble into a decamer comprising two pentameric rings.




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The nondestructive measurement of strain distributions in air plasma sprayed thermal barrier coatings as a function of depth from entire Debye–Scherrer rings

The residual strain distribution has been measured as a function of depth in both top coat and bond coat in as-received and heat-treated air plasma sprayed thermal barrier coating samples. High-energy synchrotron X-ray beams were used in transmission to produce full Debye–Scherrer rings whose non-circular aspect ratio gave the in-plane and out-of-plane strains far more efficiently than the sin2ψ method. The residual strain in the bond coat is found to be tensile and the strain in the β phase of the as-received sample was measured. The residual strains observed in the top coat were generally compressive (increasing towards the interface), with two kinds of nonlinear trend. These was a `jump' feature near the interface, and in some cases there was another `jump' feature near the surface. It is shown how these trend differences can be correlated to cracks in the coating.




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Census reveals 1,200 howler monkeys living on Barro Colorado Island

Long before dawn on a recent morning, Katie Milton and a group of stalwart volunteers, each armed with flashlight and compass, spread out into the jungle to take up positions at 35 listening stations marked on maps of the island.

The post Census reveals 1,200 howler monkeys living on Barro Colorado Island appeared first on Smithsonian Insider.




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GPS and camera traps to replace radio antennas in tracking animals on Barro Colorado Island

On the Smithsonian Tropical Research Institute's Barro Colorado Island in the Panama Canal, staff members are taking down a network of seven tall Automated Radio Telemetry System towers used to track animals wearing radio-transmitters. Scientists on the island are switching to GPS and camera trap systems to produce more data with less infrastructure.

The post GPS and camera traps to replace radio antennas in tracking animals on Barro Colorado Island appeared first on Smithsonian Insider.




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Smithsonian Conservation Biology Institute to help create frozen repository of sperm and embryonic cells for Great Barrier Reef corals

Researchers at the Smithsonian Conservation Biology Institute and partnering organizations will build a frozen repository of Great Barrier Reef coral sperm and embryonic cells. Genetic banks composed of frozen biomaterials hold strong promise for basic and applied research and conservation of species and genetic variation.

The post Smithsonian Conservation Biology Institute to help create frozen repository of sperm and embryonic cells for Great Barrier Reef corals appeared first on Smithsonian Insider.




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Alaska’s cold waters no barrier to invasive marine species, scientists say

Alaska’s pristine coastline is ripe for an influx of invasive marine species such as the European green crab and the rough periwinkle (an Atlantic sea snail) warns a new study by a team of scientists from the Smithsonian Environmental Research Center.

The post Alaska’s cold waters no barrier to invasive marine species, scientists say appeared first on Smithsonian Insider.




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Smithsonian scientists help build first frozen repository of Great Barrier Reef coral

Researchers from the Smithsonian Conservation Biology Institute, Hawaii Institute of Marine Biology and other partnering organizations spent two weeks at the end of November collecting sperm and embryonic cells during spawning from two species of coral and have built the first frozen repository for the Great Barrier Reef.

The post Smithsonian scientists help build first frozen repository of Great Barrier Reef coral appeared first on Smithsonian Insider.




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Great Barrier Reef coral Acropora tenuis

  This photo shows developing embryonic cells of the coral species Acropora tenuis, from the Great Barrier Reef in Australia. Researchers from the Smithsonian Conservation […]

The post Great Barrier Reef coral Acropora tenuis appeared first on Smithsonian Insider.







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Medications to Treat Opioid Addiction Are Effective and Save Lives, But Barriers Prevent Broad Access and Use, Says New Report

Medications to Treat Opioid Addiction Are Effective and Save Lives, But Barriers Prevent Broad Access and Use, Says New Report




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To Improve Public Health, Medicine Regulators Worldwide Should Collaborate, Remove Barriers to Sharing Information, Says New Report

Medicine regulatory authorities — including the U.S. Food and Drug Administration (FDA) — should strengthen cooperation with other countries’ regulators to ensure the quality, safety, and efficacy of medicines, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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Policy, Financing, Stigma, and Workforce Barriers Stand in the Way of Addressing Co-Occurring Opioid and Infectious Disease Epidemics

The opioid epidemic in the U.S. is driving a simultaneous epidemic of infectious diseases — including HIV, hepatitis C virus (HCV) and bacterial infections, and sexually transmitted infections — but workforce shortages, stigma, and financial and policy barriers are preventing the integration of opioid use disorder (OUD) and infectious disease services, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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Regulatory barriers to industrial symbiosis in metal sector

A new study has investigated the possibility of a regional industrial symbiosis of metal industries across the Sweden-Finland border. The analysis suggests that it is technologically feasible, but that regulatory support may be inefficient, particularly with respect to changing the status of a waste product to a by-product.




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Regulatory barriers to industrial symbiosis in metal sector

A new study has investigated the possibility of a regional industrial symbiosis of metal industries across the Sweden-Finland border. The analysis suggests that it is technologically feasible, but that regulatory support may be inefficient, particularly with respect to changing the status of a waste product to a by-product.




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Barriers to efficiency in the energy-intensive foundry industry

Increasing energy efficiency in Europe is vital to achieving a sustainable economy and tackling climate change. However, new research has shown that lack of capital and concerns about costs of disruption are major barriers to implementing energy efficiency measures in the foundry industry.




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Barriers to installing innovative energy systems in existing housing stock identified

Several barriers to upgrading existing social housing with innovative energy systems (IES) have been identified by a study of eight large-scale renovation projects in the Netherlands. These include a lack of trust between stakeholders, opposition from tenants on grounds of increased costs or delays, or poor experience with previous energy projects.




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What are the barriers to solar energy adoption?

The solar energy market is hampered by multiple barriers to adoption in the EU and worldwide, according to a new review. Researchers from Sweden and Spain found that lack of government commitment as well as various sociotechnical, management and economic barriers prevent photovoltaic technologies from being more readily adopted.




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Increasing ocean acidification affects larval barramundi’s response to underwater sound cues so they are potentially attracted to the wrong type of habitat

Since the industrial revolution, the ocean has absorbed increased levels of carbon dioxide, leading to the ocean’s pH becoming more acidic. Effects of these pH changes on marine and estuarine biota is the focus of much research effort worldwide and the authors of this study focus on the larval habitat-choice process of a commercially important tropical marine fish species, Lates calcarifer, barramundi.




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Regulatory barriers to industrial symbiosis in metal sector

A new study has investigated the possibility of a regional industrial symbiosis of metal industries across the Sweden-Finland border. The analysis suggests that it is technologically feasible, but that regulatory support may be inefficient, particularly with respect to changing the status of a waste product to a by-product.