Concern of the risk of malignancy from ionizing radiation has prompted many to advocate for judicious use of computed tomography (CT) and as low as necessary radiation doses administered per scan. Recent analysis has shown a decline in CT utilization.

We identified decreases in CT utilization between 2004 and 2012 for the 10 most common diagnostic groups receiving CT. Decreases were typically associated with increases in alternate imaging modalities. We provide a possible reason for the decrease in CT utilization. (Read the full article)

Adding second-stage automated auditory brainstem response (ABR) testing for infants who failed the initial OAE test in a two-stage neonatal hearing screening has been shown to reduce false referrals to the hearing clinic.

Infants with hearing loss may be missed by a 2-stage hearing screening because they pass the automated ABR test. In our study, a significant number of infants with hearing loss >45 decibel hearing level passed screening with automated ABR. (Read the full article)

Congenital cytomegalovirus infection is the leading infectious cause of neurologic disabilities and sensorineural hearing loss in children. Little is known concerning the frequency and impact of vestibular disorders induced by cytomegalovirus infection.

This study reports on the largest cohort of vestibular assessment of children congenitally infected with cytomegalovirus, demonstrating vestibular damages, and analyzes the correlations between vestibular dysfunction and hearing impairment or severity of infection. Cytomegalovirus infection affects postural development in children. (Read the full article)

Given the efforts to decrease the use of ionizing radiation in pediatric patients, there is significant variability in head computed tomography (CT) scan use in pediatric emergency departments for minor head trauma.

This study characterized variability in CT scan rates for all body regions in emergency department, observation, and inpatient encounters across 30 tertiary pediatric hospitals. Two-fold variation remained after case-mix adjustment, with higher volume hospitals having lower rates of CT scanning. (Read the full article)

With Box Zones, Box customers can use Amazon Web Services and IBM Cloud to store data overseas.

Le 1er juin dernier à Mugamba (province de Bururi), Pierre Nkurunziza a lancé un ultimatum. « Du haut d’une camionnette, micro à la main, sous très haute protection de l’armée et de la police », rapporte l’AFP, le président burundais a ordonné aux insurgés de cette commune du Sud du pays de déposer les armes dans les quinze jours : « Téléphonez à vos frères qui ont pris les armes, dites-leur que nous leur donnons quinze jours pour qu’ils y renoncent […] Quinze jours, pas plus. Dites-leur cela ». Hasard ou préméditation, la fin de cet ultimatum devrait coïncider avec la reprise prévue des discussions à Arusha, en Tanzanie, entre le gouvernement et l’opposition.

Objectives: Antibiotic combination therapy is used for severe infections caused by multidrug-resistant (MDR) Gram-negative bacteria. Yet, data of which combinations are most effective is lacking. This study aimed to evaluate the in vitro efficacy of polymyxin B in combination with 13 other antibiotics against four clinical strains of MDR Pseudomonas aeruginosa.

Methods: We evaluated the interactions of polymyxin B in combination with amikacin, aztreonam, cefepime, chloramphenicol, ciprofloxacin, fosfomycin, meropenem, minocycline, rifampicin, temocillin, thiamphenicol or trimethoprim by automated time-lapse microscopy using predefined cut-off values indicating inhibition of growth (≤10⁶ CFU/mL) at 24 h. Promising combinations were subsequently evaluated in static time-kill experiments.

Results: All strains were intermediate or resistant to polymyxin B, anti-pseudomonal β-lactams, ciprofloxacin and amikacin. Genes encoding β-lactamases (e.g., bla_PAO and bla_OXA-50) and mutations associated with permeability and efflux were detected in all strains. In the time-lapse microscopy experiments, positive interactions were found with 39 of 52 antibiotic combination/bacterial strain setups. Enhanced activity was found against all four strains with polymyxin B used in combination with aztreonam, cefepime, fosfomycin, minocycline, thiamphenicol and trimethoprim. Time kill experiments showed additive or synergistic activity with 27 of the 39 tested polymyxin B combinations, most frequently with aztreonam, cefepime, and meropenem.

Conclusion: Positive interactions were frequently found with the tested combinations, also against strains that harboured several resistance mechanisms to the single drugs and with antibiotics that are normally not active against P. aeruginosa. Further study is needed to explore the clinical utility of these combinations.

The records involved conversation logs between Microsoft support agents and customers across the globe, dating back to 2005. Most of the records were redacted of customer contact information, but not all.

BACKGROUND:

Approximately 25% of children with concussion have persistent postconcussive symptoms (PPCS) with resultant significant impacts on quality of life. Melatonin has significant neuroprotective properties, and promising preclinical data suggest its potential to improve outcomes after traumatic brain injury. We hypothesized that treatment with melatonin would result in a greater decrease in PPCS symptoms when compared with a placebo.

An AI-powered digital assistant to take notes for you? It’s already happening in the workplace, but classroom note taking could prove harder to automate.

Automated EFT payments enabled by technology from fintech company Ozow may be a secure alternative method to transact than card payments.

Apple's Shortcuts app can quickly and easily run a host of tasks on your Apple Watch or iOS or iPadOS device. Here's how to create and use shortcuts for Siri.

Don't settle for the default settings on your Android device. With the right launcher, you can customize the screens and layouts of your phone.

Until now, providing your own router didn't stop ISPs charging you a router rental fee.

Senior Steven Shalamanda began his education at Penn State Schuylkill knowing he was interested in becoming an optometrist. But it was this high-achieving biology student’s internship with a local practice that affirmed his vision for the future. In fall 2020, Shalamanda will begin his doctor of optometry program at the Pennsylvania College of Optometry.

The tiny, rugged Atom smartphone is being followed up with the Atom XL, which increases the display size to 4-inches and adds a 48MP camera.

The Japanese company is building the 'Woven City' in 2021, which will be used to test robotics, personal mobility, smart homes and artificial intelligence in a real-world environment populated by 2000 of its employees and researchers.

First National Bank says in a recent estate agent poll that the buy-to-let market has hit 9% of total buying - its lowest market share since its survey began.

Facebook's policy on political ads is no different than those of campaign commercials, but the social network's size and scale makes the debate more serious.

QuickBooks Online Payroll bets big on machine learning and automation to expand small to midsize business payroll options.

The new NUC is taking all sorts of forms at CES 2020, but none is as slick or as snazzy as Razer's early stab at this power-packed mini-PC platform.

No more copying and pasting tasks from email to your to-do list or chasing after customers via email. Zapier can automate these tasks and many others, too. Here's how.

Spurred by a single complaint from a customer, Delmarva Power will soon issue refunds to thousands of customers impacted by a recently identified billing error.

Following the start of production in April, capacity has been increased with a target to produce 3 million masks per month across two lines, with over 1 million masks manufactured in the first 10 days...

Javier Sotomayor talks to Sonam Saini about entering the hinterlands, rising ticket prices, and the threat from OTT players.

Using AI and machine learning capabilities, the system can be further trained to respond like a professional.

World Health Organization (WHO) plans to launch an app this month to enable people in under-resourced countries to assess whether they may have the novel coronavirus, and is considering a...

A milkman has come up with a unique way to ensure that the milk he delivers is contact-free and also forces customers to maintain the necessary distance.

Tangy and pulpy tomatoes make for an incredible addition to a heart-healthy diet. Here's how drinking home-made, fresh tomato juice may help.

 Amends Notification No. 41/1999 – Customs, dated the 28th April, 1999 - This notification exempts specified g

 Seeks to amend noti.No.146/94-Customs dated 13.07.94 so as to modify conditions for shooting equipment

 Amends Notification

 Amends Notification

 Exempts specified goods when imported into India from Nepal, from the whole of customs duty subject to certain cond

 Amends Notification

 Rescinds NotificationFull Article