Adani Transmission Ltd's (ATL) net profit in January-March at Rs 58.97 crore was 60 per cent lower than Rs 146.7 crore net profit in the same quarter last year.

Happy New Year! Have you tried the new Transmission Line Library (rfTlineLib) yet? In case you missed it, rfTlineLib was introduced in IC 6.1.6 ISR1 plus MMSIM 12.1.1 -or- MMSIM13.1. You may wonder....Why should I use the new rfTlineLib ? Well...(read more)

Renewable energy, particularly solar, is poised for significant growth in the southeastern United States. The Southeast has also mostly retained a vertically integrated utility model, and most utilities in the region have not joined a Regional Transmission Organization or Independent System Operator (collectively known as, RTO). Recent developments have led stakeholders and policymakers in the Southeast to rethink whether it is beneficial for some utilities to join RTOs – something that is generally seen as a positive development for renewable energy.

The US$1.6 billion Northern Pass transmission line that could tap into 1,096 MW from Canada’s largest hydropower producer, HydroQuebec, was approved Dec. 7, by a 6-0 vote of New Hampshire’s Site Evaluation Committee [SEC].
 

The transmission industry enters 2014 with a lot of work ahead as it continues to recreate the grid and make it more renewable energy-ready.

Offshore wind development is being pushed further out into deeper waters, emphasizing longer, higher-capacity transmission systems. Most newer offshore wind farms from Europe to the U.S. are looking at hundreds of kilometers of transmission lines: the U.K. Crown Estate's Round 3 allocations, interconnection systems from Germany's North Sea to the U.K.'s National Grid Western Link, and the proposed Atlantic Wind Connector in the U.S. Mid-Atlantic.

On what effect the U.S. Environmental Protection Agency’s (EPA) Clean Power Plan will have on transmission development in the country, including potentially a need for more transmission to transport added renewable energy, Frank Poirot, senior media specialist of transmission with Northeast Utilities (NYSE:NU) told TransmissionHub that increasing the grid's capacity to transmit power is one way to meet the growing need and enable renewable generation.

Luanda -Avec l'annonce de sept nouveaux cas, la transmission locale atteint un stade compliqu�, a admis vendredi � Luanda, le secr�taire d'�tat � la Sant� publique, Franco Mufinda. ......

Ofgem:Amendments to Gas Transmission Charging regime-minded to decision and draft impact assessment (published on 23 December 2019) The Office of Gas and Electricity Markets (Ofgem), the regulator for downstream natural gas markets, has published a ...

Title: HIV Meds Cut Transmission Risk to Zero, Even Without Condoms: Study
Category: Health News
Created: 5/2/2019 12:00:00 AM
Last Editorial Review: 5/3/2019 12:00:00 AM

ABSTRACT

RepA is a bacterial protein that builds intracellular amyloid oligomers acting as inhibitory complexes of plasmid DNA replication. When carrying a mutation enhancing its amyloidogenesis (A31V), the N-terminal domain (WH1) generates cytosolic amyloid particles that are inheritable within a bacterial lineage. Such amyloids trigger in bacteria a lethal cascade reminiscent of mitochondrial impairment in human cells affected by neurodegeneration. To fulfill all the criteria to qualify as a prion-like protein, horizontal (intercellular) transmissibility remains to be demonstrated for RepA-WH1. Since this is experimentally intractable in bacteria, here we transiently expressed in a murine neuroblastoma cell line the soluble, barely cytotoxic RepA-WH1 wild type [RepA-WH1(WT)] and assayed its response to exposure to in vitro-assembled RepA-WH1(A31V) amyloid fibers. In parallel, murine cells releasing RepA-WH1(A31V) aggregates were cocultured with human neuroblastoma cells expressing RepA-WH1(WT). Both the assembled fibers and donor-derived RepA-WH1(A31V) aggregates induced, in the cytosol of recipient cells, the formation of cytotoxic amyloid particles. Mass spectrometry analyses of the proteomes of both types of injured cells pointed to alterations in mitochondria, protein quality triage, signaling, and intracellular traffic. Thus, a synthetic prion-like protein can be propagated to, and become cytotoxic to, cells of organisms placed at such distant branches of the tree of life as bacteria and mammalia, suggesting that mechanisms of protein aggregate spreading and toxicity follow default pathways.

IMPORTANCE Proteotoxic amyloid seeds can be transmitted between mammalian cells, arguing that the intercellular exchange of prion-like protein aggregates can be a common phenomenon. RepA-WH1 is derived from a bacterial intracellular functional amyloid protein, engineered to become cytotoxic in Escherichia coli. Here, we have studied if such bacterial aggregates can also be transmitted to, and become cytotoxic to, mammalian cells. We demonstrate that RepA-WH1 is capable of entering naive cells, thereby inducing the cytotoxic aggregation of a soluble RepA-WH1 variant expressed in the cytosol, following the same trend that had been described in bacteria. These findings highlight the universality of one of the central principles underlying prion biology: No matter the biological origin of a given prion-like protein, it can be transmitted to a phylogenetically unrelated recipient cell, provided that the latter expresses a soluble protein onto which the incoming protein can readily template its amyloid conformation.

The coronavirus disease 2019 (COVID-19) epidemic, which was first reported in December 2019 in Wuhan, China, has caused 80 904 confirmed cases as of 9 March 2020, with 28 673 cases being reported outside of China. It has been declared a pandemic by the World Health Organization (WHO), has exhibited human-to-human transmissibility and has spread rapidly across countries [1]. Although the Chinese government has taken various measures to control city-to-city transmission (e.g. shutting down cities, extending holidays) and many other countries have implemented measures (such as airport screening and testing patients who have reported symptoms), the number of cases is still increasing quickly throughout the world.

Replication initiation in eukaryotic cells occurs asynchronously throughout S phase, yielding early- and late-replicating regions of the genome, a process known as replication timing (RT). RT changes during development to ensure accurate genome duplication and maintain genome stability. To understand the relative contributions that cell lineage, cell cycle, and replication initiation regulators have on RT, we utilized the powerful developmental systems available in Drosophila melanogaster. We generated and compared RT profiles from mitotic cells of different tissues and from mitotic and endocycling cells of the same tissue. Our results demonstrate that cell lineage has the largest effect on RT, whereas switching from a mitotic to an endoreplicative cell cycle has little to no effect on RT. Additionally, we demonstrate that the RT differences we observed in all cases are largely independent of transcriptional differences. We also employed a genetic approach in these same cell types to understand the relative contribution the eukaryotic RT control factor, Rif1, has on RT control. Our results demonstrate that Rif1 can function in a tissue-specific manner to control RT. Importantly, the Protein Phosphatase 1 (PP1) binding motif of Rif1 is essential for Rif1 to regulate RT. Together, our data support a model in which the RT program is primarily driven by cell lineage and is further refined by Rif1/PP1 to ultimately generate tissue-specific RT programs.

During meiotic prophase, concurrent transcription, recombination, and chromosome synapsis place substantial topological strain on chromosomal DNA, but the role of topoisomerases in this context remains poorly defined. Here, we analyzed the roles of topoisomerases I and II (Top1 and Top2) during meiotic prophase in Saccharomyces cerevisiae. We show that both topoisomerases accumulate primarily in promoter-containing intergenic regions of actively transcribing genes, including many meiotic double-strand break (DSB) hotspots. Despite the comparable binding patterns, top1 and top2 mutations have different effects on meiotic recombination. TOP1 disruption delays DSB induction and shortens the window of DSB accumulation by an unknown mechanism. By contrast, temperature-sensitive top2-1 mutants exhibit a marked delay in meiotic chromosome remodeling and elevated DSB signals on synapsed chromosomes. The problems in chromosome remodeling were linked to altered Top2 binding patterns rather than a loss of Top2 catalytic activity, and stemmed from a defect in recruiting the chromosome remodeler Pch2/TRIP13 to synapsed chromosomes. No chromosomal defects were observed in the absence of TOP1. Our results imply independent roles for Top1 and Top2 in modulating meiotic chromosome structure and recombination.

Environmental biologists have warned that the potential spread of COVID-19 via sewage 'must not be neglected' in the battle to protect human health.

The novel coronavirus -- which has infected over 3.9 million people worldwide -- has been detected in wastewater, but researchers have been unclear about the transmission risks.

Dominic Raab has warned against relaxing the UK lockdown, saying the number of Covid-19 infections in Germany grew when restrictions were eased.

The Government should avoid reopening schools too early as scientists do not fully understand coronavirus transmission between children, an NHS chief warned.

'We propose that Sars-Cov-2 may have the potential to be transmitted via aerosols,' researchers say

Researchers studying malaria in Kenya have discovered a microbe that blocks transmission of malaria from mosquitoes which could pave the way to eradicating the disease.

The Department of Justice’s Antitrust Division issued a statement today regarding Entergy Corp.’s commitments to join a regional transmission organization (RTO) and divest its transmission system; Entergy’s proposed acquisitions of the Hinds and Hot Spring generating facilities in Mississippi and Arkansas, respectively, from KGen Power Corporation; and the division’s open investigation into Entergy’s alleged anticompetitive conduct.

The Thumb Loop system is designed to meet the maximum wind energy potential of Michigan’s Thumb region as well as contribute to regional system reliability and facilitate wholesale market competition.

Genital warts may raise the risk of HIV transmission, but prevention and treatment could reduce the spread of the disease, reports a new study. The findings

Infection rate from COVID-19 is not huge according to the samples collected, and there is no community transmission in the country so far, according to Union Health Ministry.

Mosquitoes are most likely to transmit malaria in the early evening, when people are exposed, then at midnight, when people are protected by bed nets, or in the morning, according to the new study.

Developing a mobile app to trace close proximity contacts can help control coronavirus transmission, reports a new study. A team of medical researchers

Adani Transmission Limited has informed the Exchange regarding 'Outcome of Board Meeting - Disclosures as per Regulation 52(4) and (5) of the SEBI (Listing Obligations and Disclosure Requirements) Regulations, 2015'.......

Current weak labour productivity growth in many OECD countries reflects historically weak contributions from both total factor productivity (TFP) growth and capital deepening.

Imports of Transmission Apparatus & Installation in Switzerland increased to 217.28 CHF Million in March from 190.82 CHF Million in February of 2020. Imports of Transmission Apparatus & Installation in Switzerland averaged 261.75 CHF Million from 2014 until 2020, reaching an all time high of 448.64 CHF Million in November of 2017 and a record low of 190.82 CHF Million in February of 2020. This page includes a chart with historical data for Switzerland Imports of Transmission Apparatus & Installation.

Imports - Transmission Shafts & Cranks, Bearing Housings, Etc. in Mexico increased to 277592 USD THO in March from 264992 USD THO in February of 2020. Imports - Transmission Shafts & Cranks, Bearing Ho in Mexico averaged 265087.35 USD THO from 2014 until 2020, reaching an all time high of 370414 USD THO in October of 2017 and a record low of 217205 USD THO in January of 2016. This page includes a chart with historical data for Mexico Imports of Transmission Shafts & Cranks, Bearing.

Imports - Transmission Apparatus For Radiotelephony, Tv, Etc in Mexico increased to 57995 USD THO in March from 52166 USD THO in February of 2020. Imports - Transmission Apparatus For Radiotelephon in Mexico averaged 51527.49 USD THO from 2014 until 2020, reaching an all time high of 74616 USD THO in October of 2014 and a record low of 36257 USD THO in January of 2017. This page includes a chart with historical data for Mexico Imports of Transmission Apparatus For Radioteleph.

EMC32-S: Transmission of Disturbance Signal Parameters to dAV Camera Systems

London sexual health clinic 56 Dean Street released a statement urging people to get tested, saying that if new cases are picked up now it can reduce transmission when lockdown ends.

Some Chinese auto manufacturers have begun offering new design features they promise will help limit the transmission of bacteria and viruses in their vehicles, including Sars-CoV-2.

Sales rise 27.54% to Rs 13.20 crore

Sales rise 25.20% to Rs 3186.96 crore

Adani Transmission's consolidated net profit dropped 60% to Rs 59 crore on a 3% decline in operational revenue to Rs 2220 crore in Q4 March 2020 over Q4 March 2019.

Adani Transmission on Saturday reported a 60 per cent drop in consolidated net profit at Rs 58.97 crore for the March quarter. The fall was mainly on account of a one-time writeoff of Rs 185 crore finance sunk cost, it said in a regulatory filing. The company's consolidated net profit stood at Rs 146.7 crore in the quarter ended March 31, 2019. Total income of the company rose to Rs 3,317.51 crore in the quarter under review from Rs 2,569.16 crore in the year ago period. For full fiscal 2019-20, consolidated net profit rose to Rs 706.49 crore, from Rs 559.20 crore in 2018-19.

ICMR to monitor 75 districts to check for community transmission

The Union Ministry of Health and Family Welfare has continuously denied that India has entered the community transmission phase. To each question put to the government on community transmission, during government briefings, it has maintained that contact tracing is being carried out at state levels and the cases can only be classified as local and cluster transmissions.

Scientists said the structural makeup of SARS-CoV-2 suggests that it will behave differently in aqueous environments, compared to other viruses typically found in the intestine.

The company#39;s consolidated net profit stood at Rs 146.7 crore in the quarter ended March 31, 2019.

New York, NY : Oxford University Press, 2019.

New device could boost telecommunications and be adapted for photonics

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