National Health Accounts figures show the per capita out-of-pocket expenditure on health in Kerala stands at ₹7,889. However, Kerala also tops the list when it comes to the per capita government spending on health, at ₹4,338

Stockholm : Wahlström & Widstrand, 1988.

Attenzione, pickpockets! Magician Ben Seidman demonstrates and explains pickpocketing techniques in 9 levels of difficulty, from the easiest to most complex. From a traditional outside jacket pocket snatch to stealing someone's neck tie in broad daylight, this sleight-of-hand expert shows us how master pickpockets execute petty theft. Director: Maya Dangerfield Director of Photography: Dominik Czaczyk Editor: Jordan Calig Expert: Ben Seidman Creative Producer: Katherine Wzorek Line Producer: Joseph Buscemi Associate Producer: Kameryn Hamilton Production Manager: Peter Brunette Production & Equipment Manager: Kevin Balash Production Coordinator: Kariesha Kidd Camera Operator: Josh Andersen; Omar Elgohary Sound Mixer: Kari Barber Production Assistant: Fernando Barajas; Brock Spitaels Hair & Make-Up: Vanessa Renee Post Production Supervisor: Alexa Deutsch Post Production Coordinator: Ian Bryant Supervising Editor: Doug Larsen Additional Editor: Jason Malazia Assistant Editor: Justin Symonds

BRS leader faulted Congress govt in Telangana for spending ₹300 crore on ads in the media in Maharashtra in support of the Congress (MVA) there

Leader of the Opposition said that CPI(M) had raised objections when the Oommen Chandy government tried to introduce seaplanes

Paddy varieties have high protein (10.1%) and moderately high level of zinc (20 ppm) content

Emeritus's paid online education model is 'small and private' with personalised feedback

Nellore district Special POCSO Court also slaps the convict with ₹23,000 fine

People fret about increase in essential expenses and tell us their ways of coping with it

Recent surveys suggest that while the pace of price increases has declined dramatically, the public’s mood is still marred by nearly two years of high inflation

The POCO X6 Pro delivers on multiple fronts which include great performance, a nice display and decent battery life. It makes for an interesting value-for-money choice for those looking for a gaming-forward device

Does this sleek budget flagship punch above its weight?

This affordable tablet has its allures, but doesn’t exactly keep its cool

A few important life lessons amid rising prices

While the latest, fourth-generation Swift makes no pretence of being a performance car or the last word in luxury, what it does stand for is amply evident, notes Pavan Lall.

The dextransucrase DSR-OK from the Gram-positive bacterium Oenococcus kitaharae DSM17330 produces a dextran of the highest molar mass reported to date (∼109 g/mol). In this study, we selected a recombinant form, DSR-OKΔ1, to identify molecular determinants involved in the sugar polymerization mechanism and that confer its ability to produce a very-high-molar-mass polymer. In domain V of DSR-OK, we identified seven putative sugar-binding pockets characteristic of glycoside hydrolase 70 (GH70) glucansucrases that are known to be involved in glucan binding. We investigated their role in polymer synthesis through several approaches, including monitoring of dextran synthesis, affinity assays, sugar binding pocket deletions, site-directed mutagenesis, and construction of chimeric enzymes. Substitution of only two stacking aromatic residues in two consecutive sugar-binding pockets (variant DSR-OKΔ1-Y1162A-F1228A) induced quasi-complete loss of very-high-molar-mass dextran synthesis, resulting in production of only 10–13 kg/mol polymers. Moreover, the double mutation completely switched the semiprocessive mode of DSR-OKΔ1 toward a distributive one, highlighting the strong influence of these pockets on enzyme processivity. Finally, the position of each pocket relative to the active site also appeared to be important for polymer elongation. We propose that sugar-binding pockets spatially closer to the catalytic domain play a major role in the control of processivity. A deep structural characterization, if possible with large-molar-mass sugar ligands, would allow confirming this hypothesis.

MS Dhoni and his love affair with motorcycles need no introduction. Here we shed some light on Mahi's Yamaha RX135 that was one of his first bikes!

The March mayhem that saw domestic benchmark indices tank 24% in not behind investors despite a decent recovery in the month of April. However, the coming few months could be crucial for investors.

The Uruguayan is confident the manager will bring success to Tottenham, who made the bold decision to dismiss Mauricio Pochettino this season

The Policy Framework for Investment (PFI) is a comprehensive and systematic tool for improving investment conditions. The pocket edition of the PFI contains the full text of the 2015 update minus the supplemental questions and reference lists. Find the integral text and other tools online at www.oecd.org/investment/pfi.htm

The digital economy is here, and growing every day, sometimes in surprising ways. As ministers gather for major meetings in Paris and Cancun, government leaders should be in no doubt about the key role they must play in securing the digital economy’s future as a driver of productive and inclusive progress.

The worst may now be over, but as one frontline doctor reveals in her latest diary, traumatised medics now have time to reflect on the life-and-death decisions taken in the heat of battle… 

The worst may now be over, but as one frontline doctor reveals in her latest diary, traumatised medics now have time to reflect on the life-and-death decisions taken in the heat of battle… 

Tottenham will do everything they can to provide new signing Ryan Sessegnon with the platform he needs to flourish, says manager Mauricio Pochettino.

The likes of Christian Eriksen and Victor Wanyama were expected to leave in the summer but both have remained in north London, with Pochettino insisting they are in his plans.

KIERAN JACKSON: A starlit grand inception to a senior first-team player confronting a home supporter on the terraces. The Tottenham Hotspur Stadium has had quite the opening salvo.

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