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The SJDM Newsletter is ready for download

SOCIETY FOR JUDGMENT AND DECISION MAKING NEWSLETTER To All Judgment and Decision Making Aficionados: The Society for Judgment and Decision Making is pleased to announce that the latest newsletter is ready for download: http://sjdm.org/newsletters/ This issue contains announcements, conferences, and jobs!




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The SJDM Newsletter is ready for download

SOCIETY FOR JUDGMENT AND DECISION MAKING NEWSLETTER To All Judgment and Decision Making Aficionados: The Society for Judgment and Decision Making is pleased to announce that the latest newsletter is ready for download: http://sjdm.org/newsletters/ This issue contains announcements, conferences, and jobs. It also has the 2024 conference program in it, so you have that going […]




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Why Is Fidelity Always Seen as the New Four-Letter Word?

Fidelity is often seen as a bad word in school, but it doesn't have to be that way. In this guest blog by George Toman, the concept of fidelity is explained and defended.




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An Open Letter to the NAEP Governing Board

The change under consideration would make the reading test less accurate not more, writes E.D. Hirsch Jr.




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OCR Letter Says Connecticut's Policy on Transgender Athletes Violates Title IX

The U.S. Department of Education's office for civil rights says that Connecticut's interscholastic sports governing body violates Title IX with its transgender participation policy.




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Letters From Alaska

When it comes to education, the 49th state faces its own challenges, some of which are unique to Alaska and some that it shares with other rural states. This series explores how cultural and geographic barriers, teacher shortages, historical developments, and more have shaped schooling in Alaska.




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Library seeks family connected to mystery love letter

The Library is appealing to surviving family members to help provide more information about 125 year old love letters.




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Mae Jemison Reads the Letter Written by John Glenn to Honor Jeff Bezos for Blue Origin

Two weeks before he died, the legendary astronaut wrote a letter in recognition of Jeff Bezos' work, read at the 2016 American Ingenuity Awards Smithsonian magazine American #IngenuityAwards




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Writing Letters to Everyone in the World

Two British artists travel to Pittsburgh for their second installment of their "Mysterious Letters" art project.




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The Hotel Chelsea's Iconic Neon Sign Will Be Divided Into Pieces and Sold One Letter at a Time

The vertical sign stretched across three stories of the Manhattan hotel, which once welcomed the likes of Bob Dylan, Patti Smith, Andy Warhol and Janis Joplin




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News24 Business | OPINION | The four letters that will define COP29

The New Collective Quantified Goal – a post-2025 climate finance target – is set to be a defining agenda item at COP29, aiming for a more ambitious and equitable financial commitment for developing countries, says Punki Modise.




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An unexpected letter

OM EAST rejoices at God’s provision sent by post.




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An Open Letter to a Parent Afraid of Anti-Racist Education

Black Lives Matter, climate change, family separation? All appropriate classroom topics, writes Christina Torres.




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Commissioner Navarro Signs Health Policy Letter to President-Elect Biden

Joins ten Insurance Commissioners in providing short- and long-term recommendations to the incoming administration A group of the nation’s state insurance commissioners joined together in a pledge to work with President-elect Joe Biden by providing health policy recommendations to the incoming administration. The commissioners share President-elect Biden’s vision that no American should have to go […]




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DOL to Re-issue Unemployment Insurance Tax Rate Letters Due to Error

The Division of Unemployment Insurance (UI) recently mailed 2024 UI tax rate letters that contained incorrect information. We apologize for the error. We are working to correct the issue and will mail new letters with the correct rate as quickly as possible. All employers will receive updated letters even if their rate does not change. […]




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DOL Reissues Unemployment Insurance Tax Rate Letters

The Division of Unemployment Insurance has corrected the issue related to the 2024 UI tax rate letters mailed in January. Corrected letters have been mailed to employers the week of February 5, 2024. The corrected letters have a date of February 1, 2024. The Division of Unemployment would like to thank all employers for their […]




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Can An Appointment Be Rescinded / Cancelled Due To Delay In Issuing Of Relieving Letter From The Previous Employer? : Delhi High Court Judgment




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Scam Alert: Division Of Revenue Warns Taxpayers Of Fraudulent Letters

The Delaware Division of Revenue is warning the public of a new tax scam that’s happening in Delaware. Victims receive a letter from the “Tax Processing Unit” that threatens property seizure and wage garnishment unless the victim calls a toll-free number to “avoid enforcement.”



  • Division of Revenue
  • Scams
  • Tax Processing Unit

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AG Jennings issues open letter to Delaware landlords urging Delaware Landlord/Tenant Code Compliance

Attorney General Kathy Jennings‘ Fraud and Consumer Protection Division has issued an open letter to Delaware landlords regarding commonly seen illegal lease provisions in residential leases. The letter puts landlords on notice that their residential leases must comply with Delaware’s Residential Landlord/Tenant Code. Attorney General Jennings stated: “Landlords have tremendous power over their tenants. The […]



  • Department of Justice Press Releases

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Letter: Holding ex-managers accountable for irregular spending




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to write a cease and desist letter

to write a cease and desist letter




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to write a letter to parents from student teachers

to write a letter to parents from student teachers




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to write a letter of harassment in workplace

to write a letter of harassment in workplace




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to write a high school scholarship application letter

to write a high school scholarship application letter




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Richard Powers's new novel is a beautiful love letter to our oceans

From colonialism to AI, this Booker-longlisted novel urges us to wake up to how we treat wild creatures and places




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Warning Letters Target Illegal Online Sales of Opioid Meds: FDA

Title: Warning Letters Target Illegal Online Sales of Opioid Meds: FDA
Category: Health News
Created: 8/28/2018 12:00:00 AM
Last Editorial Review: 8/29/2018 12:00:00 AM




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Reply to Letter to Editor Concerning “Nocturnal Pressure Controlled Ventilation Improves Sleep Efficiency in Patients Receiving Mechanical Ventilation”




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Osteoporosis Canada guideline on screening for men likely low value [Letters]




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Fox News AI Newsletter: Who parents trust for medical advice

Stay up to date on the latest AI technology advancements and learn about the challenges and opportunities AI presents



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Fox News AI Newsletter: 'It might kill us all'

Stay up to date on the latest AI technology advancements and learn about the challenges and opportunities AI presents now and for the future.



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Editors letter: current regulatory landscape

Olivia Friett, editor of Medical Plastics News takes a look at the current regulatory landscape.




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Can a Form Letter from FDA "Blow Your Mind"?

Adam Feuerstein appears to be a generally astute observer of the biotech scene. As a finance writer, he's accosted daily with egregiously hyped claims from small drug companies and their investors, and I think he tends to do an excellent job of spotting cases where breathless excitement is unaccompanied by substantive information.


However, Feuerstein's healthy skepticism seems to have abandoned him last year in the case of a biotech called Sarepta Therapeutics, who released some highly promising - but also incredibly limited - data on their treatment for Duchenne muscular dystrophy. After a disappointing interaction with the FDA, Sarepta's stock dropped, and Feuerstein appeared to realize that he'd lost some objectivity on the topic.


However, with the new year comes new optimism, and Feuerstein seems to be back to squinting hard at tea leaves - this time in the case of a form letter from the FDA.


He claims that the contents of the letter will "blow your mind". To him, the key passage is:


We understand that you feel that eteplirsen is highly effective, and may be confused by what you have read or heard about FDA's actions on eteplirsen. Unfortunately, the information reported in the press or discussed in blogs does not necessarily reflect FDA's position. FDA has reached no conclusions about the possibility of using accelerated approval for any new drug for the treatment of Duchenne muscular dystrophy, and for eteplirsen in particular.


Feuerstein appears to think that the fact that FDA "has reached no conclusions" may mean that it may be "changing its mind". To which he adds: "Wow!"
Adam Feuerstein: This time,
too much froth, not enough coffee?


I'm not sure why he thinks that. As far as I can tell, the FDA will never reach a conclusion like this before its gone through the actual review process. After all, if FDA already knows the answer before the full review, what would the point of the review even be? It would seem a tremendous waste of agency resources. Not to mention how non-level the playing field would be if some companies were given early yes/no decisions while others had to go through a full review.


It seems fair to ask: is this a substantive change by FDA review teams, or would it be their standard response to any speculation about whether and how they would approve or reject a new drug submission? Can Feuerstein point to other cases where FDA has given a definitive yes or no on an application before the application was ever filed? I suspect not, but am open to seeing examples.


A more plausible theory for this letter is that the FDA is attempting a bit of damage control. It is not permitted to share anything specific it said or wrote to Sarepta about the drug, and has come under some serious criticism for “rejecting” Sarepta’s Accelerated Approval submission. The agency has been sensitive to the DMD community, even going so far as to have Janet Woodcock and Bob Temple meet with DMD parents and advocates last February. Sarepta has effectively positioned FDA as the reason for it’s delay in approval, but no letters have actually been published, so the conversation has been a bit one-sided. This letter appears to be an attempt at balancing perspectives a bit, although the FDA is still hamstrung by its restriction on relating any specific communications.

Ultimately, this is a form letter that contains no new information: FDA has reached no conclusions because FDA is not permitted to reach conclusions until it has completed a fair and thorough review, which won't happen until the drug is actually submitted for approval.

We talk about "transparency" in terms of releasing clinical trials data, but to me there is a great case to be made for increase regulatory transparency. The benefits to routine publication of most FDA correspondence and meeting results (including such things as Complete Response letters, explaining FDA's thinking when it rejects new applications) would actually go a long way towards improving public understanding of the drug review and approval process.




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The U.S.-Russia Initiative to Prevent Nuclear Terrorism Newsletter: November 2019 - November 2020

 

  • Elbe Group Discusses Strategic Stability, Hybrid Warfare and Terrorism.
  • Mowatt-Larssen’s Book Details Lessons He Learned While Tracking Al-Qaida’s WMD Programs.
  • Experts on New START Extension and Other Nuclear Priorities of Biden Presidency.
  • Kazakhstan’s Last HEU Eliminated.
  • William Potter Joins Russian Academy of Sciences.
  • COVID, Nuclear Security On Agenda of IAEA’s 64th General Conference.
  • Mayak Aims to Process Entire range of SNF.
  • Atomguard Reports Foiling Unauthorized Access.
  • Allison: US Vital Interest in Prevention of Nuclear Terrorism Will Continue to Guide Its North Korea Policy.
  • Learning from COVID-19 to Prepare for Nuclear Attack.
  • Hecker, Kassianova Encourage Young US and RF Professionals to Explore Lessons of Nuclear Accidents.
  • Experts Weigh in on 75th Anniversary of Hiroshima Bombing.
  • A New Look at IAEA’s Nuclear Security Recommendations.
  • Azerbaijan Has Threatened to Strike Armenia’s NPP With Missiles.
  • IAEA Notified of 189 Incidents Of Material Being Out Of Regulatory Control in 2019.
  • Russia To Retrieve More Radioactive Debris from Bottom of Ocean.
  • Researchers Propose Fast Way to Detect Weapons Grade Materials.
  • Keeping Nuclear Power Plants Out of Reach of Terrorists During the Coronavirus Pandemic.
  • Bunn, Tobey and Roth Testify on Prevention of Nuclear Theft, Call for Cooperation With Russia.
  • Budapest Memorandum Parsed.
  • IAEA Holds A Ministerial on Nuclear Security.
  • Assessing Progress on Nuclear Security.
  • 12th GUMO Officer On Trial for Embezzlement.
  • Lukashenko: Pompeo Alerted Me to Nuclear Materials at Border.
  • US and Russia Reported HEU and Plutonium to IAEA.
  • IAEA Bank Receives LEU.
  • GICNT Hosted 8 Multilateral Activities in 2019.

 

 




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The U.S.-Russia Initiative to Prevent Nuclear Terrorism Newsletter: November 2020 - November 2021

 

  • U.S.-Russia Elbe Group Maintains Focus on Threat of Nuclear Terrorism.
  • Former Chernobyl Plant Manager Bryukhanov Dies.
  • Matthew Bunn on Threat to Nuclear and Radiological Transports.
  • On 9/11 Anniversary Russian Officials Call for Resumption of U.S.-Russian CT Cooperation.
  • Experts Weigh in on 9/11 Anniversary.
  • U.S. and Norway Agree to Eliminate All of Norway’s HEU.
  • Two Soviet Nuclear Submarine Reactors Located.
  • Russian Security Council: Terrorists Remain Interested in NBC.
  • IAEA Adopts Resolutions on Nuclear Security, NS Center Planned.
  • Allison on Risk of Mega-terrorist Attack After U.S. Withdrawal From Afghanistan.
  • Arbatov Warns of Enduring Threat of Nuclear Terrorism to Russia in His New Volume.
  • Russia’s New Security Strategy Drops References to CT Partnership With U.S.
  • NNSA’s Non-Proliferation Budget to Decrease in ’22, Provides for US and Russian Visits.
  • Should U.S.-Russian Interaction in Cyberspace Involve CT? 
  • Russia’s NPP Operator Conducts Emergency Preparedness Exercise.
  • Putin and Biden Discuss Terrorist Threat Emanating from Afghanistan, but No Deal.
  • U.S. Experts on Ensuring Access to Neutrons While Reducing Nuclear Terrorism Risks.
  • Beebe Weighs in on U.S.-Russian CT Interaction.
  • Duo Detained for Alleged Attempt to Sell Americium-241.
  • 12th GUMO Guard’s Sentence Upheld.
  • NDAA-Mandated Group to Identify Nuclear Terrorism Risks.
  • Belfer’s MTA Hosts Conference on Lessons of Fukushima and Chernobyl.
  • Russia Withdraws from Uranium Hexafluoride Transportation Deal with U.S.
  • Bell: U.S. Needs to Convince Russia on Contending With Nuclear Terrorism Threat.
  • U.S. and Canada Complete Repatriation of HEU Material.
  • Siegfried Hecker Outlines his Vision of Future for Nuclear Security Cooperation.
  • Hackers Breach U.S. Nuclear Agency.
  • Tobey on Assassinations of Nuclear Scientists and Terrorists.
  • Rosatom Has Checked Nuclear Sites, Following a Tip on Terrorism from U.S.




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An Open Letter to Volvo Truck Workers in Dublin, Virginia

To the members of UAW Local 2069: I don’t think you can realize how much of an inspiration you are to how many people. The battle you’re fighting goes far beyond the immediate issues. We’re living in a world where you can’t open your eyes without seeing a cause for despair: the pandemic, first of … Continue reading An Open Letter to Volvo Truck Workers in Dublin, Virginia




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Lady Whiskerdown’s Letters from the Cat Cafe

This piece of literary mayhem is exclusive to Smart Bitches After Dark, but fret not. If you'd like to join, we'd love to have you! Have a look at our membership options, and come join the fun! If you want to have a little extra fun, be a little more yourself, and be part of keeping the site open for everyone in the future, we can’t wait to see you in our new subscription-based section … Continue reading Lady Whiskerdown’s Letters from the Cat Cafe




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Will Today be a Red Letter Day for The Deceased Organ Donation Programme in India?

Finally, after many a debate and discussion, the proposed amendments to the Transplantation of Human Organs Act will be




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HVS Asia Pacific Hospitality Newsletter - Week Ending 8 November 2024

Hotel Properties Limited Acquires Concorde Hotel in Singapore




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Van Gogh on art and artists : letters to Emile Bernard [Electronic book] / Vincent van Gogh ; edited and translated by Douglas Lord.

Mineola, New York : Dover Publications, [2013]




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The epistle of James [Electronic book] : linguistic exegesis of an early Christian letter / edited by James D. Dvorak and Zachary K. Dawson.

Eugene, Oregon : Pickwick Publications ; Hamilton, Canada : McMaster Divinity College Press, [2019]




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Gujarat DDU-GKY Program: Over 30,000 rural youth trained, 450 receive job appointment letters




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Letters to The Editor — July 12, 2024




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Letters to The Editor — July 13, 2024




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Letters to The Editor — July 15, 2024




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Letters to The Editor — July 16, 2024




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Letters to The Editor — July 17, 2024




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Letters to The Editor — July 18, 2024




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Letters to The Editor — July 19, 2024




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Letters to The Editor — July 22, 2024




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Letters to The Editor — July 23, 2024