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National Academies Gulf Research Program Now Accepting Applications for 2019 Early-Career Research and Science Policy Fellowships

The Gulf Research Program (GRP) of the National Academies of Sciences, Engineering, and Medicine is now accepting applications for its Early-Career Research Fellowships and Science Policy Fellowships for 2019.




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Child Poverty Rate Could Be Cut in Half in Next Decade Following Proposals in New Expert Report

In light of the many costs generated by child poverty for the United States, a new report from the National Academies of Sciences, Engineering, and Medicine provides evidence-based policy and program packages that could cut the child poverty rate by as much as 50 percent while at the same time increasing employment and earnings among adults living in low-income families.




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National Academies Gulf Research Program Announces 2019 Science Policy Fellowship Recipients

The Gulf Research Program of the National Academies of Sciences, Engineering, and Medicine has announced the nine recipients of its 2019 Science Policy Fellowships.




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National Academies Review of Report on Supplemental Low-Activity Waste at Hanford Nuclear Site Now Available for Public Comment

A new report from the National Academies of Sciences, Engineering, and Medicine – which reviews a separate report by a federally funded laboratory that examines options for treating low-activity radioactive waste at the Hanford Nuclear Reservation -- is available for public comment until Oct. 31.




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Twenty Scientists Awarded 2019 Early Career Research Fellowships by National Academies Gulf Research Program

The Gulf Research Program of the National Academies of Sciences, Engineering, and Medicine announced today the recipients of its 2019 Early-Career Research Fellowships.




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National Academy of Medicine Names Five NAM Fellows for 2019

The National Academy of Medicine (NAM) has selected five outstanding health professionals for the class of 2019 NAM Fellowships. The fellows were chosen based on their professional qualifications, reputations as scholars, professional accomplishments, and relevance of current field expertise to the work of the NAM and the Health and Medicine Division of the National Academies of Sciences, Engineering, and Medicine (the National Academies).




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The Ford Fellowship Family - Empowering Scholarship and Diversity

For decades, the Ford Foundation Fellowship programs have contributed to building a more equitable and diverse U.S. higher education system.




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How To Allow/allow For Session/block Cookies In Firefox




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Help cleansing computer following a virus/ ransomware attack




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Flowbird rolls out pay station feature for kiosks

Flowbird Group has announced recent developments that limit...




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UAE's FIs requested to use regtech to follow AML guidelines

The United Arab Emirates’ (UAE) regulatory authorities have asked local businesses to implement appropriate fintech and regtech solutions to counter money laundering. 




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Businesses, Parks And Beaches Open Slowly As Phase Two Of Reopening Begins Today

Amoeba Music store, a Hollywood landmark is closed amid the COVID- 19 pandemic, on May 7, 2020, in Hollywood, California. ; Credit: VALERIE MACON/AFP via Getty Images

AirTalk®

The City and County of Los Angeles began the process today of reopening some parts of the economy that had been shuttered due to COVID-19. 

Starting today, businesses including book stores, toy stores, sporting goods stores, florists and other “low-risk” retailers will be allowed to reopen for curbside service only. All other shopping will still need to be done over the phone or online. Businesses will also have to have strategies in place for stemming the spread of COVID-19 on site, which will need to include employee training, sanitation protocols and even screening measures. Offices, dine-in restaurants and shopping malls remain closed, as do beauty salons, barbershops, live event venues and other places where people might be in close proximity. Meanwhile, in Orange County, the final stretches of coastline were approved to reopen on Thursday, though they are under the same “active use” rules that the other beaches in OC have implemented in order to prevent people from congregating on beaches and in parking lots.

Today on AirTalk, we’ll talk about the specifics of what is and is not reopening today in L.A. City and County, get an update from the Los Angeles Flower Market in downtown, and find out about the latest on Orange County Beaches.

Guests:

Emily Guerin, reporter for KPCC covering small businesses; she tweets @guerinemily

Lisa Brenner, associate editor at LAist; she tweets @lisa_brenner

Laylan Connelly, beaches reporter for The Orange County Register; she tweets @ocbeaches

Candice Kim, whose parents owns a flower shop in Downtown LA that reopened today.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Windows 10 slow download speed please help




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Years After The Gas Blowout, Recriminations Continue In Porter Ranch

Deirdre Bolona displayed a photo of her and her late father Matt Koenig at a state legislative oversight hearing about the Aliso Canyon natural gas disaster. ; Credit: Sharon McNary/KPCC

Sharon McNary

It’s been nearly four years since the smell and chemicals from a ruptured gas well at an underground storage field forced thousands of Porter Ranch residents to leave their neighborhood for months. The recriminations and protests have not stopped.

State legislators held a hearing in Porter Ranch Tuesday to review how gas field owner Southern California Gas and public officials responded to the blowout. 

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Federal Appeals Court Panel Clears Path To Executions, Throwing Out Lower Court Order

David Welna | NPR

Two judges appointed by President Trump to the District of Columbia Circuit Court of Appeals prevailed Tuesday in a ruling that clears the way for the executions of four inmates.

The only dissenter in the 3-2 ruling was Judge David Tatel, an appointee of former President Bill Clinton. The judges were reviewing a lower court's injunction that had blocked the scheduled executions.

The decision was seen as a win for Trump's Justice Department, which issued new guidelines last July that would have allowed the federal government to carry out its first executions in 16 years.

The fates of the four men remain unresolved because their death sentences were sent back to the lower court for further proceedings.

In December, the U.S. Supreme Court declined the Justice Department's request to vacate the lower court's injunction that scuttled the planned executions.

At issue is the question of whether the condemned men should be put to death by the injection of only one barbiturate — pentobarbital — as called for in the Justice Department's July 2019 memo.

Many of the 28 states where the death penalty is still legal require a lethal injection cocktail containing not one but three barbiturates. Those states include Indiana, where the scheduled executions were to take place.

Pharmaceutical companies have stopped producing at least one of the three drugs used in that lethal mixture, and several botched executions have resulted from some states using untested formulas.

The 1994 Federal Death Penalty Act calls for executions to be carried out "in the manner prescribed by the law of the State in which the sentence is imposed."

Judge Gregory Katsas argues in his majority opinion that the "manner prescribed" simply refers to the method of execution rather than the protocols each state follows in carrying out each kind of execution.

"The government says that 'manner' here means 'method'," Katsas writes, "such that the FDPA regulates only the top-line choice among execution methods such as hanging, electrocution, or lethal injection. In my view, the government is correct."

Judge Neomi Rao, in a concurring opinion, argues that while the word "manner" refers not only to the method of execution, it cannot be interpreted in isolation. "It is a broad, flexible term," she says, "whose specificity depends on context."

In his dissent, Tatel says the best understanding of the 1994 statute is that it "requires federal executions to be carried out using the same procedures that states use to execute their own prisoners.

"Had Congress intended to authorize the Attorney General to adopt a uniform execution protocol," Tatel argues, "it knew exactly how to do so."

Copyright 2020 NPR. To see more, visit https://www.npr.org.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Rick Bright, Former Top Vaccine Scientist, Files Whistleblower Complaint

Rick Bright, former director of the Biomedical Advanced Research and Development Authority, is seen here in 2018.; Credit: Toya Sarno Jordan/Bloomberg via Getty Images

Laurel Wamsley | NPR

Updated at 6:14 p.m. ET

The federal scientist who was ousted from his role as director of the Biomedical Advanced Research and Development Authority has filed a whistleblower complaint with the U.S. Office of Special Counsel.

Rick Bright was a high-ranking federal scientist focused on vaccine development and a deputy assistant secretary with the Department of Health and Human Services. Last month, Bright said he was transferred to a "less impactful position" at the National Institutes of Health after he was reluctant to promote the use of drugs such as hydroxychloroquine to treat COVID-19 patients.

In the complaint, Bright alleges a range of government wrongdoing by Dr. Robert Kadlec, the assistant secretary of preparedness and response at the U.S. Department of Health & Human Services, and others. Bright's boss was Kadlec, who in turn reported to HHS Secretary Alex Azar.

At the time of his removal, Bright said he had been ousted because of his "insistence" that the government spend funds on "safe and scientifically vetted solutions" to address the coronavirus crisis and not on "drugs, vaccines and other technologies that lack scientific merit."

Bright says in the complaint that he raised concerns about the need to prepare for the coronavirus in January but encountered opposition from Trump administration officials. He says he was transferred out of BARDA in retaliation.

According to the complaint, relations between Bright and Kadlec had been strained since 2018 or so, when Bright began "raising repeated objections to the outsized role Dr. Kadlec allowed industry consultants to play in securing contracts that Dr. Bright and other scientists and subject matter experts determined were not meritorious."

"Once the COVID-19 pandemic hit, however, Dr. Bright became even more alarmed about the pressure that Dr. Kadlec and other government officials were exerting on BARDA to invest in drugs, vaccines, and other technologies without proper scientific vetting or that lacked scientific merit," the complaint continues. "Dr. Bright objected to these efforts and made clear that BARDA would only invest the billions of dollars allocated by Congress to address the COVID-19 pandemic in safe and scientifically vetted solutions and it would not succumb to the pressure of politics or cronyism."

The complaint alleges that Bright made repeated efforts to get the U.S. government to make adequate preparations for coronavirus, but was stymied by political appointees leading the HHS, including Azar.

HHS did not immediately respond to NPR's request for comment.

Bright says that in an effort to get the word out to the public about the risks associated with hydroxychloroquine, he shared with a reporter nonclassified emails between HHS officials that "discussed the drug's potential toxicity and demonstrated the political pressure to rush these drugs from Pakistan and India to American households." He says Azar and Kadlec removed him from his post within days of publication of an article about chloroquine because they suspected he was the article's source.

Bright says he stopped receiving a paycheck on April 20 and has not been assigned any further duties.

News of the whistleblower complaint was made public by his attorney on Tuesday.

Copyright 2020 NPR. To see more, visit https://www.npr.org.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Cal State Fullerton Announces Plans For A Virtual Fall. Will Other Colleges Follow?

Elissa Nadworny | NPR

On Monday, California State University, Fullerton announced it was planning to begin the fall 2020 semester online, making it one of the first colleges to disclose contingency plans for prolonged coronavirus disruptions.

"Our plan is to enter [the fall] virtually," said Pamella Oliver, the schools provost, at a virtual town hall. "Of course that could change depending on the situation, depending on what happens with COVID-19. But at this point that's what we're thinking."

The public institution in Southern California also said it hopes to resume in-person learning when it's safe to do so.

Oliver asked faculty to start planning for fall virtual classes now, citing the pain felt this spring when the university was forced to transition to online classes. "Having to jump quickly, without having in-depth plans," she said, "added to the difficulty."

Colleges and universities moved spring classes online, and many also closed campuses in response to the coronavirus pandemic. Schools are now grappling with how long the disruptions will last, and what the fall semester will look like, but many have been hesitant to announce their fall plans publicly.

College enrollment was already on a downward trend before the pandemic, making it a competitive field for college recruiters — every student they sign up counts. The big question is: Will students still enroll if college is all online? And will colleges that were already in dire financial straits survive the outbreak?

Copyright 2020 NPR. To see more, visit https://www.npr.org.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Patt's Hats: A lei illusion and yellow shoe madness

Patt Morrison's outfit from her June 5, 2013 Patt's Hats entry. ; Credit: Michelle Lanz/KPCC

Patt Morrison

There are so many things  I like about this dress – the sleeve length, the boat neck, the fact that it’s navy and not black, and the fact that it wasn’t made in Bangladesh – but mostly it’s the gaily asymmetrical floral design that caught my eye.

The pattern is front and back, and I’m a stickler about those things. It looks like I have been loaded down with festive leis, but also loaded with one too many Mai Tais, so the flower garlands are askew as if I were listing a little bit.

There’s more of my current yellow shoe madness with these very Michelle Obama kitten-heel slingbacks in two different tones of yellow, one a more acid shade and the other more canary, or perhaps chrome yellow. That’s not to be confused with “Crome Yellow,” a very sardonic Aldous Huxley novel parodying the artsy intelligentsia set of 1920s England.

I hope you can see this bracelet. It’s a piece of Victorian mourning jewelry. The Victorians went way, way over the top on this stuff; some of it borders on the ghoulish, with lockets containing elaborately braided locks or even portraits or scenes made entirely from the hair of the deceased. I can admire the artistry but the sentiment can seem excessive. This piece, though, has a black and white enamel border around a tiny fly. Why a fly, I wondered. Then I read the inscription inside:

“From JR to AHR [clearly a husband to a wife] in loving memory of our darling little May Queen, died 7th August 1880, age 14 Mos.”

That inscription made the fly make sense. It’s a mayfly, a creature that lives a few days, or even just a few minutes, and here was this little girl, born in May – hence the May Queen reference to the mythical springtime queen of antiquity -- and died barely a year thereafter. So sweet, so sad, so human, all from an inscription on a bracelet. The girl’s parents are long dead, and so too are any siblings she may have had, but it can touch us more than 130 years later.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Patt's Hats: Flowy fabrics, chunky jewelry and mismatching shoes

Patt Morrison's ensemble for Aug 8, 2013.; Credit: Dave Coelho/KPCC

Patt Morrison

What shall we call this color scheme? How about ‘Manhattan Mermaid’?

The petrel blues, the turquoises, the aquas – and then that uptown/downtown black, in this case a black linen duster over a Peter Max-style splashy-print silk dress. The way the hem pools at the sides a bit reminds me of the cut of Pre-Raphaelite ladies’ tunics; I’d love to dress “period” for a week to see whether I’d like it.

Imagine, a week of hoop skirts … a week of 1950s tailleurs … a week of bustles … a week of hobble skirts … a week of liberated Pre-Raphaelite velvet gowns!

The hat is so unmistakably summer in fabric and color that it doesn’t get out of the hatbox as much as it should, poor thing. And the shoes – I did not get them together, honest, but even though the prints don’t match, it’s the dissonance that makes them work better together than if they had.

The fabric is a very textured canvas and printed like batik. [They are not the soul of comfort – oh what a dreadful pun, but is there any other kind of pun? – but they look smart hooked over the railing of a chair in a chic bistro, which is where I intend to take them!]

And the bracelets, one from a great-aunt who had a fine eye for jewelry – the turquoise is almost Persian, it’s so green, but it’s more likely to be American. The cuff is definitely Southwest, with the rope-pattern trim and the irregularly shaped bezels, although the turquoises themselves are symmetrical.

Because I’m left-handed, my right arm bears the singular honor of being “ornamental,” and bearing the burden of the bling.

Summer on, ladies!

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Better monitoring of low level pollutants needed to protect marine life

A new study of pollutants in Mediterranean coastal waters assesses the risks posed by difficult-to-detect chemicals present at low concentrations. Coastal monitoring programmes may be required to control discharges of some of these pollutants, which, at current levels, could be harmful to sensitive marine creatures.




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NFL Commissioner Roger Goodell says he never considered resigning following abuse scandals

NFL Commissioner Roger Goodell talks during a press conference at the Hilton Hotel on Sept. 19, 2014 in New York City. Goodell spoke about the NFL's failure to address domestic violence, sexual assault and drug abuse in the league.; Credit: Elsa/Getty Images

Update 1:04 p.m. Goodell: 'Same mistakes can never be repeated'

Commissioner Roger Goodell says the NFL wants to implement new personal conduct policies by the Super Bowl. At a news conference Friday, Goodell made his first public statements in more than a week about the rash of NFL players involved in domestic violence. He did not announce any specific changes, but said he has not considered resigning.

"Unfortunately, over the past several weeks, we have seen all too much of the NFL doing wrong," he said. "That starts with me."

The league has faced increasing criticism that it has not acted quickly or emphatically enough concerning the domestic abuse cases.

The commissioner reiterated that he botched the handling of the Ray Rice case.

"The same mistakes can never be repeated," he said.

Goodell now oversees all personal conduct cases, deciding guilt and penalties.

He said he believes he has the support of the NFL's owners, his bosses.

"That has been clear to me," he said.

The Indianapolis Colts' Darius Butler was among those who tweeted criticism of the press conference:

Colts tweet 1

Colts tweet 2

The commissioner and some NFL teams have been heavily criticized for lenient or delayed punishment of Rice, Adrian Peterson and other players involved in recent domestic violence cases. Less than three weeks into the season, five such cases have made headlines, the others involving Greg Hardy, Ray McDonald and Jonathan Dwyer.

Vikings star running back Peterson, Carolina defensive end Hardy and Arizona running back Dwyer are on a special commissioner's exemption list and are being paid while they go through the legal process. McDonald, a defensive end for San Francisco, continues to practice and play while being investigated on suspicion of domestic violence.

As these cases have come to light, such groups as the National Organization of Women and league partners and sponsors have come down hard on the NFL to be more responsive in dealing with them. Congress also is watching to see how the NFL reacts.

In response to the criticism, the NFL announced it is partnering with a domestic violence hotline and a sexual violence resource center.

Goodell also said in a memo to the clubs late Thursday that within the next 30 days, all NFL and team personnel will participate in education sessions on domestic violence and sexual assault. The memo said the league will work with the union in providing the "information and tools to understand and recognize domestic violence and sexual assault."

The league will provide financial, operational and promotional support to the National Domestic Violence Hotline and the National Sexual Violence Resource Center.

12:07 p.m. Roger Goodell to break silence on domestic abuse and the NFL

Roger Goodell will make his first public statements in more than a week about the rash of NFL players involved in domestic violence when he holds a news conference Friday.

The NFL commissioner will address the league's personal conduct policy. The league has faced increasing criticism it has not acted quickly or emphatically enough concerning the domestic abuse cases.

His last public appearance was at a high school in North Carolina on Sept. 10.

The commissioner and some NFL teams have been heavily criticized for lenient or delayed punishment of Ray Rice, Adrian Peterson and other players involved in recent domestic violence cases. Less than three weeks into the season, five such cases have made headlines, the others involving Greg Hardy, Ray McDonald and Jonathan Dwyer.

Vikings star running back Peterson, Carolina defensive end Hardy and Arizona running back Dwyer are on a special commissioner's exemption list and are being paid while they go through the legal process. McDonald, a defensive end for San Francisco, continues to practice and play while being investigated on suspicion of domestic violence.

As these cases have come to light, such groups as the National Organization of Women and league partners and sponsors have come down hard on the NFL to be more responsive in dealing with them. Congress also is watching to see how the NFL reacts.

In response to the criticism, the NFL announced it is partnering with a domestic violence hotline and a sexual violence resource center.

Goodell also said in a memo to the clubs late Thursday that within the next 30 days, all NFL and team personnel will participate in education sessions on domestic violence and sexual assault. The memo said the league will work with the union in providing the "information and tools to understand and recognize domestic violence and sexual assault."

The league will provide financial, operational and promotional support to the National Domestic Violence Hotline and the National Sexual Violence Resource Center.

"These commitments will enable both the hotline and NSVRC to help more people affected by domestic violence and sexual assault," Goodell said in the memo.

The National Domestic Violence Hotline provides domestic violence victims and survivors access to a national network of resources and shelters. It is available 24 hours a day, seven days a week in 170 languages. Goodell noted that the hotline received 84 percent more calls from Sept. 8-15, and the organization said more than 50 percent of those calls went unanswered because of lack of staff.

"The hotline will add 25 full-time advocates over the next few weeks that will result in an additional 750 calls a day being answered," he said.

NSVRC supports sexual violence coalitions across the United States. The NFL's initial support will be directed toward state coalitions to provide additional resources to sexual assault hotlines.

This story has been updated.




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Can Uber lower fares and have its drivers make more money?

For the first time, Uber will guarantee drivers an hourly wage of $20 an hour in Los Angeles, or $26 during peak times.; Credit: David Ramos/Getty Images

Ben Bergman

To keep demand high during the slower winter months, the ridesharing service, Uber, has cut fares by 20 percent in 48 markets – including Los Angeles and Orange County.

The company says a trip from West Hollywood to downtown will now be around nine dollars, instead of $11.

When Uber lowered prices in the past to muscle out competitors like Lyft and taxi services, passengers loved it but drivers have complained it puts an unfair squeeze on them, complaining their already low take went even lower.

Uber stresses the fact cutting fares actually helps drivers because they get more business. In a blog post, the company points to data from Chicago where fares dropped 23 percent last month compared to December 2013 while drivers' income increased by 12 percent.

But drivers have been skeptical whether volume can make up for the price drop. The company's claim that New York city drivers earn a median of $90,766 a year has been refuted. Slate talked to New York UberX driver Jesus Garay in October:

“They say it doesn’t hurt the pocket of the drivers,” Garay says of the 20 percent fare cuts. “It does. Because it’s impossible with those numbers to be in business.”

The way drivers see it, ride volume can only increase so much in response to lower prices. Garay says that on average, a ride takes him 20 minutes from start to finish: five minutes to reach the pickup location, five to wait for the customer, and 10 to drive to the destination. For a trip of that length, Garay says he’ll make $10 or $11. “So if you’re busy, you’re going to make three rides in an hour,” he explains. 

Newly flush with a $40 billion valuation, Uber is now willing to put its money where its mouth is; For the first time, Uber will guarantee its partners – as it calls them -  an hourly wage of $20 an hour in Los Angeles, or $26 during peak times. (The guarantee comes with a few conditions: Drivers have to accept 90% of trips, average at least one trip per hour, and be online for 50 minutes of every hour worked)

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Astronomers find a golden glow from a distant stellar collision

Full Text:

On August 17, 2017, scientists made history with the first direct observation of a merger between two neutron stars. It was the first cosmic event detected in both gravitational waves and the entire spectrum of light, from gamma rays to radio emissions. The impact also created a kilonova -- a turbocharged explosion that instantly forged several hundred planets’ worth of gold and platinum. The observations provided the first compelling evidence that kilonovae produce large quantities of heavy metals, a finding long predicted by theory. Astronomers suspect that all of the gold and platinum on Earth formed as a result of ancient kilonovae created during neutron star collisions. Based on data from the 2017 event, first spotted by the Laser Interferometer Gravitational-wave Observatory (LIGO), astronomers began to adjust their assumptions of how a kilonova should appear to Earth-bound observers. A team of scientists reexamined data from a gamma-ray burst spotted in August 2016 and found new evidence for a kilonova that went unnoticed during the initial observations.

Image credit: NASA/ESA/E. Troja





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My Chrome Browser is not allowing me to access YouTube????




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Alexion's Buyout of Portola Pharmaceuticals Gets Investors' Blood Flowing

Source: Streetwise Reports   05/05/2020

Shares of Portola Pharmaceuticals traded 130% higher after the company reported that it has received an $18 per share buyout offer from Alexion Pharmaceuticals.

Commercial-stage biotechnology company Portola Pharmaceuticals Inc. (PTLA:NASDAQ), which focuses on blood-related disorders, and global biopharmaceuticals firm Alexion Pharmaceuticals Inc. (ALXN:NASDAQ) announced that they have entered into a definitive merger agreement for Portola to be acquired by Alexion.

The acquisition is said to provide a key addition to Alexion's diversified commercial portfolio. The report indicated that the merger agreement has already been unanimously approved each of the company's boards of directors.

The report explained that "Portola's commercialized medicine, Andexxa® [coagulation factor Xa (recombinant), inactivated-zhzo], marketed as Ondexxya® in Europe, is the first and only approved Factor Xa inhibitor reversal agent, and has demonstrated transformative clinical value by rapidly reversing the anticoagulant effects of Factor Xa inhibitors rivaroxaban and apixaban in severe and uncontrolled bleeding."

Portola's President and CEO Scott Garland commented, "In developing and launching Andexxa, Portola has established a strong foundation for changing the standard of care for patients receiving Factor Xa inhibitors that experience a major, life-threatening bleed. Andexxa rapidly reverses the pharmacologic effect of rivaroxaban and apixaban within two minutes, reducing anti-Factor Xa activity by 92 percent...Given their enhanced resources, global footprint and proven commercial expertise, we look forward to working with Alexion to maximize the value of Andexxa. With their commitment to commercial excellence, together, we will be able to drive stronger utilization of Andexxa, increase penetration and accelerate adoption in the critical care setting."

Ludwig Hantson, Ph.D., CEO of Alexion, remarked, "The acquisition of Portola represents an important next step in our strategy to diversify beyond C5. Andexxa is a strategic fit with our existing portfolio of transformative medicines and is well-aligned with our demonstrated expertise in hematology, neurology and critical care...We believe Andexxa has the potential to become the global standard of care for patients who experience life-threatening bleeds while taking Factor Xa inhibitors apixaban and rivaroxaban. By leveraging Alexion's strong operational and sales infrastructure and deep relationships in hospital channels, we are well positioned to expand the number of patients helped by Andexxa, while also driving value for shareholders."

The firms advised that "under the terms of the merger agreement, a subsidiary of Alexion will commence a tender offer to acquire all of the outstanding shares of Portola's common stock at a price of $18 per share in cash." Alexion plans to fund the purchase with existing cash on hand and the transaction is expected to close in Q3/20. The purchase is subject to approval by a majority interest of Portola's common stockholders tendering their shares along with ordinary closing conditions and regulatory approvals. The company noted that "following successful completion of the tender offer, Alexion will acquire all remaining shares not tendered in the offer at the same price of $18 per share through a merger."

Alexion is a global biopharmaceutical company based in Boston, Mass., with offices in 50 countries worldwide. The company states that it has been "the global leader in complement biology and inhibition for more than 20 years and that it has developed and commercializes two approved complement inhibitors to treat patients with paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome, as well as the first and only approved complement inhibitor to treat anti-acetylcholine receptor antibody-positive generalized myasthenia gravis and neuromyelitis optica spectrum disorder."

Portola is headquartered in South San Francisco, Calif., and is a commercial-stage biopharmaceutical company focused on treating patients with serious blood-related disorders. Specifically, the company is engaged in developing and commercializing novel therapeutics in order to advance the fields of thrombosis and other hematologic conditions. The firm listed that its first two commercialized products are Andexxa® and Bevyxxa® (betrixaban), and that it is also advancing and developing cerdulatinib, a SYK/JAK inhibitor for use in treatment of hematologic cancers.

Portola Pharmaceuticals started off the day with a market capitalization of around $609.0 million with approximately 78.5 million shares outstanding and a short interest of about 23.0%. PTLA shares opened 130% higher today at $17.85 (+$10.09, +130.03%) over yesterday's $7.85 closing price. The stock has traded today between $17.71 and $17.91 per share and is currently trading at $17.83 (+$10.07, +129.77%).

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Disclosure:
1) Stephen Hytha compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. He or members of his household own securities of the following companies mentioned in the article: None. He or members of his household are paid by the following companies mentioned in this article: None.
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3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security.
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5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the interview or the decision to write an article until three business days after the publication of the interview or article. The foregoing prohibition does not apply to articles that in substance only restate previously published company releases.
6) This article does not constitute medical advice. Officers, employees and contributors to Streetwise Reports are not licensed medical professionals. Readers should always contact their healthcare professionals for medical advice.




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Climate change impacts not yet detectable in river flow data




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Global groundwater pumping lowers the flow of water bodies and threatens freshwater and estuarine ecosystems

Groundwater is the earth’s largest freshwater resource and is vital for irrigation and global food production. In dry periods farmers pump groundwater to water crops, this is already happening at an unsustainable level in many places — exceeding the rate at which rain and rivers can refill the groundwater stores. This study seeks to identify where groundwater pumping is affecting stream flows and estimates where and when environmentally critical stream flows — required to maintain healthy ecosystems — can no longer be sustained.




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Low-carbon product design: look at the parts to improve the whole

Researchers have developed a method to identify the parts that contribute the most to a product's greenhouse gas (GHG) emissions and evaluate alternative design solutions. When applied to a LCD television, it showed that GHG emissions could be cut by 36 per cent by using alternative parts to those currently used.




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Getting the most from substance flow analyses

New research from Sweden identifies the characteristics of substance flow analyses that make them useful to policy makers. Substance flow analyses that focus on measuring rather than modelling pollution and which are aligned to existing measures are more likely to influence policy.




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Mediterranean diet associated with lower risk of death in cardiovascular disease patients

28 Aug 2016: The Mediterranean diet is associated with a reduced risk of death in patients with a history of cardiovascular disease, according to results from the observational Moli-sani study presented at ESC Congress 2016 today.1

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  • Health & Medicine

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Prevalence of celiac appears steady but followers of gluten-free diet increase

More people are eating gluten-free, although the prevalence of celiac disease appears to have remained stable in recent years, according to an article published online by JAMA Internal Medicine.

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  • Health & Medicine

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Pesticide pollution slow to reach groundwater

Underground water aquifers are a significant source of drinking water. In a recent study, French researchers found that pesticides applied to crops can take many years to sink down through the ground and reach groundwater. This means that they may still be entering aquifers, even after agricultural application has stopped.




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Impact of volunteer GM maize on conventional crops is low

A recent EU-supported study has analysed the development of volunteer or ‘rogue’ GM (genetically modified) maize plants in a conventional crop field. It finds that their numbers are low and do not exceed the EU’s threshold of 0.9 per cent for incidental GM content.




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Lower diversity of soil organisms in new farmland

Converting grassland to arable land can reduce the diversity of nematodes, predatory mites, earthworms and enchytraeid worms in the soil, according to a study by Dutch researchers. However, they found that restoring arable land to grassland did not fully restore the diversity of these four groups during the course of the four-year study.




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Rebuilding the physical and social environment following natural disasters

In the aftermath of natural disasters, displaced communities require temporary accommodation. A new study has examined how the built environment of these temporary communities influences their recovery and resilience, using accommodation set up after Hurricane Katrina as a case study. It highlights the importance of developing transitional built environments that consider the social and mental health needs of a community.




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Zoom slowing down your Windows PC?




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Laptop became very slow / also Internet is very slow "Mailware"?




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New map of global energy flow

Researchers have developed a new energy map that traces the flow of global energy from the fuel sources to the final services provided. The study provides new insight into the potential of energy efficiency measures by focusing on technologies rather than economic sectors.




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Tropical land use change: more carbon lost for lower crop yield

Land cleared in the tropics loses nearly twice as much carbon and produces less than half the annual crop yield as land in temperate zones, according to researchers. Their analysis of the trade-off between crop production and the loss of carbon stored in vegetation highlights the need to target reforestation in the tropics.




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New approach to developing scenarios for future of low carbon cities

A new study has explored how cities can create a low carbon future by presenting an approach to stakeholder engagement that develops scenarios of an ideal city. Rather than projecting towards a low carbon target for the future, the study suggests that ‘backcasting’ to the present day from these scenarios may provide a useful goal-orientated approach to environmental planning in cities.




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Air pollution slows growth of coral reefs in the Caribbean

Periods of slow growth observed in coral reefs in the Caribbean are caused by aerosols in the air from pollution and volcanic activity, recent research suggests. Aerosols cause cooler sea surface temperatures and reduce the amount of sunlight reaching the coral, both of which slow coral growth.




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Energy efficiency in low-income households: study explores the role of feedback in reducing energy consumption

Although low-income households consume less energy than wealthier households, they are still keen to learn how to save energy, for both economic and environmental reasons. This is the conclusion of a recent Swedish study which explored the energy-related behaviour of residents on low incomes. It provides insights which could help inform energy-awareness campaigns targeted at this section of the population.




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Indian IT leans on govt spends, managed services as deals slow

IT advisory IDC estimates that domestic IT spending will decline 4.5% to $55.5 billion this fiscal




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Environmental impacts of batteries for low carbon technologies compared

A recent study has assessed some of the environmental impacts of the production of batteries used with low carbon systems, such as photovoltaic cells and wind turbines. The results indicate that lithium-based batteries have the most significant impact, in terms of metal depletion and greenhouse gas (GHG) emissions, but more complete data are needed on possible toxic impacts to conduct a full comparison between batteries.




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New technology offers low cost noise monitoring

Networks of wireless sensors could be used to monitor traffic noise. A new study shows that the wifi sensor systems, although slightly less accurate than precision noise monitoring systems, can provide detailed information, with dense coverage, about traffic noise over a longer period. Their low cost and low energy requirements make them particularly suitable and attractive for use by local authorities or even community groups.




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Energy-consumption feedback cut electricity use by up to 27% in low-income Mediterranean households

Electricity consumption fell by 22–27% in low-income households participating in an energy-efficiency programme in Cyprus, France, Malta and Spain, reports a new study. Participants were provided with a range of tools and information to help them curb their energy use, including smart meters and customised reports. The results confirm the value of tailoring information to specific demographic groups.




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Which new low-carbon technologies can be developed and commercialised quickly? New research offers analysis

A new study provides clues as to which innovative low-carbon technologies will successfully get onto the market quickly. The historical analysis of 16 energy technologies — from steam engines to wind power — found that the average length of a product’s ‘formative phase’ is 22 years. This important period of innovation in a technology’s development is shorter for products which do not need extensive new infrastructure or changes to user behaviour. The findings could help policymakers identify new technologies that can be deployed more rapidly to meet short-term environmental targets.




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Interesting problem fixed with slow boot.