Hello! I have updated this very popular post to include a free downloadable PDF of this checklist.  Preparation is key to successful management of any project, and design projects are no different. The more preparation that both client and designer do right at the start, the more smoothly the work will go. I find checklists […]

Web designers: we’ve got fabulous news for you. With the global market expanding without limits, clients are more demanding than ever before. They understand that the highly competitive business realm requires creative websites. That’s good news: as competition increases, web development projects become more challenging. That’s good news for Be Theme too as it is […]

The post Tips on developing creative websites that will wow your clients appeared first on WebAppers.

By Lauren McCauley Common Dreams Even scientists who question findings say ‘we ignore James Hansen at our peril.’ Dr. James Hansen, the former NASA scientist who is widely credited with being one of the first to raise concerns about human-caused … Continue reading →

By Jake Johnson Common Dreams And colleague says “global warming” no longer strong enough term. “Global heating is technically more correct because we are talking about changes in the energy balance of the planet.” Declaring that after three decades of … Continue reading →

The success of any organization strongly depends on the marketing strategies they use to reach their potential customers. Law firms are no exception since they also operate in a competitive field...

By Julia  Conley Common Dreams “Our message as scientists is simple: Our planet’s future climate is inextricably tied to the future of its forest.” With a new statement rejecting the notion that drastically curbing emissions alone is enough to curb … Continue reading →

By Julia Conley Common Dreams “Nature is not a ‘nice to have’—it is our life-support system.” Scientists from around the world issued a stark warning to humanity Tuesday in a semi-annual report on the Earth’s declining biodiversity, which shows that … Continue reading →

By Jessica Corbett Common Dreams “We face a stark choice [between] radical, disruptive changes to our physical world or radical, disruptive changes to our political and economic systems to avoid those outcomes.” As people across the globe mobilize to demand … Continue reading →

By The EPA The U.S. Environmental Protection Agency (EPA) today launched a new online portal that will provide local leaders in the nation’s 40,000 communities with information and tools to increase resilience to climate change. Using a self-guided format, the … Continue reading →

Environmental activist and Academy Award®-winning actor Leonardo DiCaprio and Academy Award®-winning filmmaker Fisher Stevens premier their documentary film, Before the Flood, a compelling account of the powerful changes occurring on our planet due to climate change. Before the Flood will … Continue reading →

By Kristie Auman-Bauer Penn State News Climate change is causing glaciers to shrink, temperatures to rise, and shifts in human migration in parts of the world, according to a Penn State researcher. Brian Thiede, assistant professor of rural sociology, along … Continue reading →

By David Suzuki The David Suzuki Foundation Seeing terms like “post-truth” and “alternative facts” gain traction in the news convinces me that politicians, media workers and readers could benefit from a refresher course in how science helps us understand the … Continue reading →

By Jessica Corbett Common Dreams “We face a stark choice [between] radical, disruptive changes to our physical world or radical, disruptive changes to our political and economic systems to avoid those outcomes.” As people across the globe mobilize to demand … Continue reading →

By Julia Conley Common Dreams “Nature is not a ‘nice to have’—it is our life-support system.” Scientists from around the world issued a stark warning to humanity Tuesday in a semi-annual report on the Earth’s declining biodiversity, which shows that … Continue reading →

By Jake Johnson Common Dreams And colleague says “global warming” no longer strong enough term. “Global heating is technically more correct because we are talking about changes in the energy balance of the planet.” Declaring that after three decades of … Continue reading →

By Jessica Corbett Common Dreams “We face a stark choice [between] radical, disruptive changes to our physical world or radical, disruptive changes to our political and economic systems to avoid those outcomes.” As people across the globe mobilize to demand … Continue reading →

By Bianca Nogrady Ensia A growing number of initiatives are giving corporations the resources to help achieve global climate goals regardless of government support “We are still in.” On June 5, 2017, with these four words a group of U.S. … Continue reading →

ErdH{o}s and Hajnal constructed a 4-coloring of the triples of an $N$-element set such that every $n$-element subset contains 2 triples with distinct colors, and $N$ is double exponential in $n$. Conlon, Fox and R"odl asked whether there is some integer $qge 3$ and a $q$-coloring of the triples of an $N$-element set such that every $n$-element subset has 3 triples with distinct colors, and $N$ is double exponential in $n$. We make the first nontrivial progress on this problem by providing a $q$-coloring with this property for all $qgeq 9$, where $N$ is exponential in $n^{2+cq}$ and $c>0$ is an absolute constant.

Domain of mathematical logic in computers is dominated by automated theorem provers (ATP) and interactive theorem provers (ITP). Both of these are hard to access by AI from the human-imitation approach: ATPs often use human-unfriendly logical foundations while ITPs are meant for formalizing existing proofs rather than problem solving. We aim to create a simple human-friendly logical system for mathematical problem solving. We picked the case study of Euclidean geometry as it can be easily visualized, has simple logic, and yet potentially offers many high-school problems of various difficulty levels. To make the environment user friendly, we abandoned strict logic required by ITPs, allowing to infer topological facts from pictures. We present our system for Euclidean geometry, together with a graphical application GeoLogic, similar to GeoGebra, which allows users to interactively study and prove properties about the geometrical setup.

By Evan H. DeLucia Courtesy of EOS Critics of biofuels like ethanol argue they are an unsustainable use of land. But with careful management, next-generation grass-based biofuels can net climate savings and improve their ecosystems. As the world seeks strategies … Continue reading →

The purpose of this container is to be able to use the Amazon ASK CLI and Amazon AWS CLI in a Docker container in DevOps pipelines.

Note: This is a fork from the martindsouza image with these changes:

Once upon a time, Clint Eastwood, a notoriously outspoken conservative in supposedly liberal Hollywood, had no problem at all with cops who employed their own unconventional extra-legal brand of law enforcement (see: Dirty Harry). Today, in Richard Jewell, he really doesn't like the FBI.…

Back in November, we wrote about local singer-songwriter Eliza Johnson's musical project Eliza Catastrophe and her new album You, which she released on pre-loaded MP3 players. One thing we weren't able to mention in our interview — for contractual reasons — is that she had only a couple months prior auditioned for American Idol, and her performance finally aired on the ABC reality competition show Sunday night.…

A catastrophic loss in biodiversity, reckless destruction of wildland and warming temperatures have allowed disease to explode. Ignoring the connection between climate change and pandemics would be “dangerous delusion,” one scientist said. The scientists who study how diseases emerge in a changing environment knew this moment was coming.…

For people who love playing, a day on the worst possible golf course is better than any day not swinging the clubs.…

Before my car broke down, I didn't ride the bus.…

A library of macrocyclic compounds of the formula (I) where part (A) is a bivalent radical, a —(CH2)y— bivalent radical or a covalent bond;where part (B) is a bivalent radical, a —(CH2)z— bivalent radical, or a covalent bond;where part (C) is a bivalent radical, a —(CH2)t— bivalent radical, or a covalent bond; andwhere part (T) is a —Y-L-Z— radical wherein Y is CH2 or CO, Z is NH or O and L is a bivalent radical. These compounds are useful for carrying out screening assays or as intermediates for the synthesis of other compounds of pharmaceutical interest. A process for the preparation of these compounds in a combinatorial manner, is also disclosed.

A process for conversion of aliphatic bicyclic amines to aliphatic diamines including contacting one or more bicyclic amines selected from the group consisting of 3-azabicyclo[3.3.1]nonane and azabicyclo[3.3.1]non-2-ene with ammonia and hydrogen, and alcohols in the presence of heterogeneous metal based catalyst systems, a metal selected from the group consisting of Co, Ni, Ru, Fe, Cu, Re, Pd, and their oxides at a temperature from 140° C. to 200° C. and a pressure from 1540 to 1735 psig for at least one hour reactor systems; forming a product mixture comprising aliphatic diamine(s), bicyclic amine(s), ammonia, hydrogen, and alcohol(s); removing said product mixture from the reactor system; removing at least some of the ammonia, hydrogen, water, alcohols, bicyclic amines from said product mixture; thereby separating the aliphatic diamines from said product mixture.

Systems and methods are disclosed that may be implemented for network management system (NMS) configuration management support for network devices using a learning and natural language processing application to capture the usage and behavior of the Command Line Interface (CLI) of a network device with the aid of a CLI knowledge model, which in one example may be ontology-based.

Heterocyclic compounds of formula (I) useful as imaging probes of Tau pathology in Alzheimer's disease are described. Compositions and methods of making such compounds are also described.

[Problem] To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogues and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases.[Means of Solving the Problem]A compound of Formula (1): (where n is 0 to 2; p is 0 to 4; h is 0 to 3; j is 0 to 3; k is 0 to 2; a ring B is an aryl group or a heteroaryl group; X is O, S, or —NR7—; J1 is —CR11aR11b— or —NR11c—; J2 is —CR12aR12b— or —NR12c—; and R1 to R12c are specific groups),a salt of the compound, or a solvate of the salt or the compound.

The present invention provides a compound useful as an agent for the prevention or treatment of a sex hormone-dependent disease or the like. That is, the present invention provides a fused heterocyclic derivative represented by the following general formula (I), a pharmaceutical composition containing the same, a medicinal use thereof and the like. In the formula (I), ring A represents 5-membered cyclic unsaturated hydrocarbon or 5-membered heteroaryl; RA represents halogen, alkyl, alkenyl, alkynyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl or the like ; ring B represents aryl or heteroaryl; RB represents halogen, alkyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl or the like; E1 and E2 represent an oxygen atom or the like; U represents a single bond or alkylene; X represents a group represented by Y, —SO2—Y, —O—(alkylene)—Y, —O—Z in which Y represents Z, amino or the like; Z represents cycloalkyl, heterocycloalkyl, aryl, heteroaryl or the like; or the like.

Polyamide molding materials for transparent molding parts. The materials comprise transparent copolyamides that contain: (A) 40 to 100 wt % of at least one transparent copolyamide with a glass transition temperature (Tg) of at least 80° C. and not more than 150° C., composed of at least two diamines that are different from each other, wherein the at least two diamines are a mixture of (a) 50 to 90 mol % bis-(4-amino-3-methylcyclohexyl)methane (MACM) and/or bis-(4-amino-3-ethylcyclohexyl)methane (EACM) and/or bis-(4-amino-3,5-dimethylcyclohexyl)methane (TMACM) and b) 10 to 50 mol % aliphatic diamine having 9 to 14 carbon atoms, in particular decandiamine, particularly preferably at least 20 mol % decandiamine, each relative to the total amount of diamines, and of one or more aliphatic dicarboxylic acids, having 6 to 36 carbon atoms, (B) 0 to 60 wt % of at least one further polymer, (C) 0 to 10 wt % of additives, the sum of the components (A), (B) and (C) totaling 100% by weight.

A glycerol derivative which is effective to reduce blood pressure and has the formula: ##STR1## wherein R1 is an alkyl group having 10-22 carbon atoms, R2 is a lower acyl group or benzoyl, each of R3 and R4 independently is hydrogen or a straight or branched chain alkyl group having 1-6 carbon atoms; each of R5, R6 and R7 independently is hydrogen, a straight or branched chain alkyl group having 1-6 carbon atoms, an aryl group or an aralkyl group; and each of m and n independently is 0 or a positive integer under the condition of m+n=2-8.

The present invention relates to novel heterocycle-substituted diphosphonic acids, and the pharmaceutically-acceptable salts and esters thereof, in which the diphosphonate-substituted carbon atom moiety is attached to a carbon atom in a nitrogen-containing six membered ring heterocycle, preferably a piperidine ring. The heterocycle-substituted diphosphonic acid compounds have the general structure: ##STR1## wherein Z is a nitrogen-containing six membered ring heterocycle moiety selected from piperidinyl, diazinyl and triazinyl; m, n and m+n are from 0 to 10; Q is a covalent bond or a moiety selected from oxygen, sulfur or nitrogen; and R1, R2, R3 and R4 are substituent groups.The present invention further relates to pharmaceutical compositions containing these novel compounds. Finally this invention relates to methods for treating or preventing diseases characterized by abnormal calcium and phosphate metabolism by utilizing a compound or pharmaceutical composition of the present invention.

A composite material and method of making and using the same is described. In particular a dental (and preferably photocurable) composite material, and the use of a composite material according to the invention as a dental material and a method for preparation of a composite material according to the invention. Also disclosed are novel radically polymerizable monomers comprising at least one polyalicyclic structure element and certain ethylenic structure elements, which are particularly suitable for use in a composite material according to the invention.

Methods for converting toxic waste, including nuclear waste, to quasi-natural or artificial feldspar minerals are disclosed. The disclosed methods may include converting, chemically binding, sequestering and incorporating the toxic waste into quasi-natural or artificial Feldspar minerals. The quasi-natural or artificial feldspar minerals may be configured to match naturally occurring materials at a selected disposal site. Methods for the immediate, long term, quasi-permanent disposal or storage of quasi natural or artificial feldspar materials are also disclosed.

In embodiments of driver interface functions to interface client function drivers, a set of serial communication protocol driver interfaces are exposed by a core driver stack, and the serial communication protocol driver interfaces include driver interface functions to interface with client function drivers that correspond to client devices configured for data communication in accordance with the serial communication protocol. A client function driver can check for the availability of a driver interface function before interfacing with the core driver stack via the serial communication protocol driver interfaces. A contract version identifier can also be received from the client function driver via an extension of the driver interface functions, where the contract version identifier indicates a set of operation rules by which the client function driver interfaces with the core driver stack.

Methods and apparatus for client-allocatable bandwidth pools are disclosed. A system includes a plurality of resources of a provider network and a resource manager. In response to a determination to accept a bandwidth pool creation request from a client for a resource group, where the resource group comprises a plurality of resources allocated to the client, the resource manager stores an indication of a total network traffic rate limit of the resource group. In response to a bandwidth allocation request from the client to allocate a specified portion of the total network traffic rate limit to a particular resource of the resource group, the resource manager initiates one or more configuration changes to allow network transmissions within one or more network links of the provider network accessible from the particular resource at a rate up to the specified portion.

A method is disclosed which may include analyzing communication requests in a business process between a client and a server offering a service application to be tested. The method may further include identifying a call to a web service in the analyzed communication. The method may also include determining a location of a Web Service Description Language (WSDL) file relating to the web service on a remote server and downloading the WSDL file from the determined location. A computer readable medium having stored thereon instructions for performing the method and a computer system are also disclosed.

The present invention relates generally to client-server architectures for allowing generic upload and download functionality between a web application at a server and a client. One exemplary method includes sending a download/upload request to a web application at the server, where the download/upload request specifies at least one file to download/upload; receiving a transmission from the server; parsing the transmission to identify a download/upload command and an associated download/upload manifest, where the download/upload manifest includes executable code that, when executed on the client, will perform the download/upload of the at least one file.

The present invention relates to a process for preparing cyclic compounds having at least eight carbon atoms and at least one keto group, to the cyclic compounds obtained by this process and to the use thereof, in particular as fragrance or for providing a fragrance.

An optically active bicyclic compound is efficiently produced by optical resolution using an optically active amine.

Fault Current Limiters (FCL) provide protection for upstream and/or downstream devices in electric power grids. Conventional FCL require the use of expensive conductors and liquid or gas cryogen handling. Disclosed embodiments describe FCL systems and devices that use lower cost superconductors, require no liquid cryogen, and are fast cycling. These improved FCL can sustain many sequential faults and require less time to clear faults while avoiding the use of liquid cryogen. Disclosed embodiments describe a FCL with a superconductor and cladding cooled to cryogenic temperatures; these are connected in parallel with a second resistor across two nodes in a circuit. According to disclosed embodiments, the resistance of the superconducting components and its sheath in the fault mode are sufficiently high to minimize energy deposition within the cryogenic system, minimizing recovery time. A scheme for intermediate heat storage also is described which allows a useful compromise between conductor length enabled energy minimization and allowable number of sequential faults to enable an overall system design which is affordable, and yet allows conduction cooled (cryogen free) systems which have fast recovery and allows for multiple sequential faults.