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‘Apex Legends' brings back duos and Kings Canyon permanently

The next Apex Legends event is about to get underway and while that might only last for a few weeks, Respawn is bringing back a couple of key features on a permanent basis. The original Kings Canyon map will join the current World's Edge arena on rotation after it recently popped back up for a limited time. Meanwhile, the duos mode that debuted last fall is returning for good alongside the original trios option. They'll both come back on April 7th.




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'Apex Legends' season five will add PvE hunts to the mix

Like every other free-to-play battle royale game out there, Apex Legends is constantly refreshing the game with new content and modes. Season five “Fortune’s Favor” kicks off next week, and along with the newly-revealed character Loba, Respawn is als...




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Column: Boeing's board shouldn't escape blame in 737 Max scandal

Boeing will be hobbled by the 737 Max affair for years to come. Yet the board that oversaw this calamity is not being held to task.




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How I broke my VR skepticism and found emotional escape during coronavirus sheltering

Better VR headsets and experiences that respond to you are reasons to isolate inside virtual reality when COVID-19 is the reality outside your door.




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Cityscapes as you've never seen them - with light pollution removed

Starry night skies are near impossible to admire if you're living in a city heavily polluted by light. 




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Man in hospital after jumping from window of block of flats to escape fire

The fire started in the kitchen of a second floor flat on Wendon Road, in Baguley



  • Greater Manchester News

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Prehistoric sea creatures evolved pebble-shaped teeth to crush shellfish

Ichthyosaurs were marine reptiles during the time of the dinosaurs, and scientists don't know much about their ancestry. But by CT-scanning the fossil of one of the first ichthyosaurs, scientists discovered pebble-shaped teeth hidden in its short snout. These strange teeth, probably used for crushing the shells of snails and clam-like bivalves, help illuminate the ways that early ichthyosaurs filled different roles in Triassic marine ecosystems.




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What the papers say- May 7

Thursday’s front pages are dominated by anticipation of the easing of lockdown restrictions.




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VE Day remembered as 'day of hope' and lockdown exit plans lead the papers

The marking of Victory in Europe and the coronavirus lead the Friday papers.




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How Florence Nightingale shaped the way modern nurses are tackling coronavirus

Nightingale pioneered many of the practices carried out today, such as maintaining good hygiene and regularly washing hands




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VE Day celebrations and potential lockdown easing lead the papers

Saturday’s papers are dominated by the 75th anniversary of VE Day.




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China's face-mask diplomacy could reshape power in south-east Asia

Chinese aid and medical experts are flying around the world to help other countries hit by COVID-19. But will the assistance redraw the strategic map?




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Microsoft just revamped its cheapest and fanciest Surface devices

Two new pairs of headphones join the laptops and tablets in today's announcement.




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Tomic is TA’s ‘cheapest investment’

JOHN Tomic rejects claims his son Bernard is Australian tennis’ “Four Million Dollar Man.”




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Daw committed to stand trial over alleged rape

North Melbourne footballer Majak Daw has been committed to stand trial over the alleged rape of a teenage girl in 2007.




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Bubble-wrapped windows and foam-taped doors: How to keep warm for less this winter

Fancy your home as an "hermetically sealed space ship" this winter, and keeping warm to boot? Here's how you can do both and not pump out more electricity, gas or wood smoke.



  • Energy
  • Electricity Energy and Utilities
  • House and Home

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Cheaper Australian-made ventilator offers greater ICU capability option amid coronavirus pandemic

An Australian-made ventilator that costs a tenth of the price of existing models is brought to life in just four weeks, which could revolutionise intensive care capability in the fight against COVID-19.




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Coles, Woolworths ease coronavirus restrictions on toilet paper

Customers will be able to buy multiple packets of toilet paper at the supermarket giants, although a number of other items remain restricted.




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Why this former US Congress hopeful is betting on a small country newspaper

Michael Waite ran for office in Washington and worked for Bill Gates' private investment company, but helping establish a community newspaper could be his toughest challenge yet.




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Murray Bridge journalist launches online service after ACM suspends newspaper

A journalist left out of work after Australian Community Media shut down his regional printing press starts his own online newspaper in an effort to keep the community informed.




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COVID-19 on the brain? Here are eight vitamins to get your immune system in shape


Certain vitamins, minerals and other supplements can support your immune system as a whole, even though they haven’t been researched for their impact on COVID-19 specifically.




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Senior media figures warn of COVID-19 'perfect storm' hitting newspapers

Senior media figures have warned of the coronavirus "perfect storm" hitting newspapers, saying the drop in circulation and ad revenue could lead to some outlets disappearing completely.




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NIH 'Shark Tank' to Develop Faster, Cheaper, More Reliable COVID-19 Tests

(MedPage Today) -- WASHINGTON -- Millions more coronavirus tests are needed to curb the spread of the virus and guide decisions around safely reopening businesses and schools, Sen. Lamar Alexander (R-Tenn.), chair of the Senate Health, Education...




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MAGA Babe, Hillary Toilet Paper and Al Gore: The Weird World of the Virtual 2020 Campaign

The Trump-Biden fight is already underway, and it's totally online. What it's like to spend seven days following their whirlwind all-digital faceoff.




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AFL to be played in 'very different landscape' after coronavirus pandemic

The coronavirus shutdown has already had a big impact on the AFL — but could the effects spill over into the way the game is played in future?




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Mal Meninga accuses NRL of using former CEO Todd Greenberg as scapegoat

The rugby league immortal defends Todd Greenberg, who has fallen on his sword, calling on the league to share the blame for the poor financial state it finds itself in during the coronavirus pandemic.




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NRL players agree to new pay deal as May 28 restart takes shape

The NRL ticks another box ahead of its planned restart later this month, as the players officially sign off on a new pay agreement ahead of a return to training this week.




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Coronavirus: What shape will a recession and recovery take?

Monica Miller explains the alphabet soup of possible recession shapes for the coronavirus-hit global economy.




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Carlos Ghosn: Turkey charges seven over escape from Japan

The former Nissan chief's sensational escape involved being smuggled from Tokyo to Lebanon via Istanbul.




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M.R. Asks 3 Questions: Jay Chapel, CEO, ParkMyCloud

The challenges businesses and services are facing right now vary from wild fluctuations in supply chains; to enormous digital demand on the technologies and platforms that enable us to stay connected and live productive lives. This is why Jay Chapel is looking for ways to help organizations reduce costs across the board. Collecting information from great companies, we hope our conversation shares some ideas that may help in some small way.

Keep on reading: M.R. Asks 3 Questions: Jay Chapel, CEO, ParkMyCloud




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Indian analytical instruments industry expects low govt funding & curtailed Capex in post─COVID─19 phase




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Teknor Apex develops new series of TPEs

Advanced chemistry developed by Teknor Apex has yielded a new series of ThermoPlastic Elastomers (TPEs) for over-moulding that exhibit adhesion to engineering plastic substrates while meeting the requirements for use in medical devices.




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Lyra Therapeutics IPO Raises $56M for Tests of Tech for Runny Noses

Lyra Therapeutics, a biotech company developing a new way to treat your persistently runny nose, has raised $56 million in its public markets debut. Late Thursday, Lyra offered 3.5 million shares priced at $16 apiece, which was the high end of its projected $14 to $16 price range. Those shares are expected to begin trading […]




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PTC Therapeutics to Acquire Censa Pharma for Mid-Stage Rare Disease Drug

PTC Therapeutics has reached an agreement to acquire Censa Pharmaceuticals and its lead asset, an experimental metabolic disorder therapy that is now being prepared for a pivotal study. The deal, announced after the market close Wednesday, will bring South Plainfield, NJ-based PTC (NASDAQ: PTCT) another compound for its pipeline of rare disease drugs. Wellesley, MA-based […]




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Disarm Therapeutics hires Dr Alvin Shih as new President and CEO

Massachusetts-based biotech Disarm Therapeutics has hired Dr Alvin Shih as their new President and CEO.

The Cambridge, Mass.-based firm has set itself the task of creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central drive of neurological disease.

Dr Shih brings to the role a range of experiences. Having graduated with a biology degree from Vanderbilt University in 1996, Shih joined management consultancy McKinsey where he worked as a business analyst for two years.

read more




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Seres Therapeutics appoints Dr Lisa von Moltke as new Chief Medical Officer

Dr Lisa von Moltke has left Aklermes and has joined Seres Therapeutics as its new Chief Medical Officer.

Chief Executive Officer at Seres, Eric Shaff, said Seres will benefit from von Moltke’s “extensive experience directing successful development programs, leading clinical teams, and interacting with regulatory agencies across multiple areas of medicine.”

read more




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Novartis acquires digital therapeutics specialist Amblyotech

The pharmaceutical firm has purchased the company, which specializes in advancing treatments and diagnostics for ocular disorders.



  • Markets & Regulations

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Express Scripts + Prime Therapeutics: Our Four Takeaways From This Market Changing Deal (rerun)

This week, I’m rerunning some popular posts while I prepare for this Friday’s video webinar: Industry Update and COVID-19 Impact: PBMs & Payers.

I suspect this deal will remain profitable for the participating companies even as COVID-19 alters the US. prescription payer mix. Click here to see the original post and comments from January 2020. National market shares for the largest PBMs in 2019 appears as Exhibit 88 of our 2020 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers.

P.S. Sorry that today's meme is one day too late for Star Wars day.



Just before the holidays, Cigna’s Express Scripts business announced a market-changing deal with Prime Therapeutics. Click here to read the press release.

There's been very little written about this transaction, though it has potentially major implications. Below, I share my thoughts on the following topics arising from the deal:
  • Implications for manufacturers and pharmacies
  • The role of the secretive Ascent Health Services
  • What this all means for Walgreens
  • Why the Federal Trade Commission won’t challenge the deal
A few weeks ago, I explained why integrated insurer / PBM / specialty pharmacy / provider organizations are poised to restructure U.S. drug channels. The Express Scripts / Prime deal signals that the channel will continue its amazing pace of reinvention.

The scale, scope, and interconnectedness of today’s market participants make the system increasingly resistant to massive disruption from either external players like Amazon or a government takeover. Like it or not, the channel will continue to gain power and extract profit. Read on and see if you agree.
Read more »
        




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Oligonucleotide Therapeutics and Delivery Conference 2020

16 - 17 September 2020, London, UK.
Oligonucleotide therapeutics - the emerging medicine class - are harnessing the therapeutic benefit of targeting genetic material via antisense, mRNA, RNAi, saRNA and siRNA. Their market growth: CAGR of 13.7% projected to reach USD 8.2 billion by 2024 is driven by their potential to provide more efficacious and less toxic alternatives to small molecules.




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PTC Therapeutics to acquire Censa Pharmaceutical

In another strategic M&A deal announced so far this month, PTC Therapeutics has entered into an agreement…



  • Biotechnology/Censa Pharmaceuticals/Companies
  • mergers and acquisitions/Metabolics/PTC Therapeutics/Rare diseases/sepiapterin/USA

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Justice Department Reaches Settlement with SmallTownPapers Inc., Regarding Employment Rights of Air Force Reservist

The Department has reached a settlement that, if approved by the court, will resolve a lawsuit the Department filed on behalf of Air Force Reservist Frank Bonnin against SmallTownPapers Inc., (SmallTownPapers). The complaint, filed in August 2008 in U.S. District Court in Seattle, alleged that SmallTownPapers violated the Uniformed Services Employment and Reemployment Rights Act of 1994 (USERRA) when it terminated Bonnin from his position as director of publisher relations due to his military obligation as an Air Force Reservist to attend active duty training.



  • OPA Press Releases

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Justice Department Files Lawsuit Against City of Chesapeake, Virginia, to Enforce the Employment Rights of Virginia Coast Guard Reservist

The Justice Department today filed a lawsuit in U.S. District Court in Norfolk, Va., on behalf of U.S. Coast Guard Reserve member Paul Sutton against the city of Chesapeake alleging violations of the Uniformed Services Employment and Reemployment Rights Act of 1994 (USERRA).



  • OPA Press Releases

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Justice Department Files Lawsuit Against Stonescape Pavers LLC to Enforce Employment Rights of U.S. Air Force Reservist

The Department today filed a lawsuit in U.S. District Court in Las Vegas against Stonescape Pavers LLC alleging that the company willfully violated the Uniformed Services Employment and Reemployment Rights Act of 1994 (USERRA) by firing Matthew T. Denning without cause when he returned from active duty.



  • OPA Press Releases

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FBI Arrests Jordanian Citizen for Attempting to Bomb Skyscraper in Downtown Dallas

Hosam Maher Husein Smadi, 19, has been arrested and charged in a federal criminal complaint with attempting to use a weapon of mass destruction.



  • OPA Press Releases

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Hampton Roads Sanitation District, Virginia, Agrees to Settle Clean Water Act Violations in Chesapeake Bay Area

Hampton Roads Sanitation District (HRSD), based in Virginia Beach, Va., has agreed to pay a $900,000 civil penalty and to take corrective actions to reduce alleged sanitary sewer overflows from its collection system and nine sewage treatment plants that have polluted the Chesapeake Bay and its tributaries.



  • OPA Press Releases

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Justice Department Moves to Intervene in Adult Homes Case Against the State of New York to Help Shape Remedy

The United States alleges that the state of New York has failed to house thousands of individuals with mental illness who currently reside in large, institutional “adult homes” in the most integrated setting, in violation of Title II of the Americans with Disabilities Act (ADA) and Section 504 of the Rehabilitation Act.



  • OPA Press Releases

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Justice Department Settles Citizenship Status Discrimination Matter Against ValleyCrest Landscape Companies

The Department announced a settlement agreement with ValleyCrest Landscape Companies to resolve charges of hiring discrimination against U.S. citizens and other work-authorized domestic workers at its Virginia locations.



  • OPA Press Releases

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Man Admits Attempting to Use a Weapon of Mass Destruction to Bomb Skyscraper in Downtown Dallas

Hosam Maher Husein Smadi pleaded guilty today before U.S. District Judge Barbara M. G. Lynn to a felony offense related to his attempted bombing of a downtown Dallas skyscraper in September 2009.



  • OPA Press Releases

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Man Sentenced to 24 Years in Prison for Attempting to Use a Weapon of Mass Destruction to Bomb Skyscraper in Downtown Dallas

Hosam Maher Husein Smadi was sentenced today by U.S. District Court Judge Barbara M. G. Lynn to 24 years in prison for his attempted bombing of a downtown Dallas skyscraper in September 2009.



  • OPA Press Releases

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Department of Justice Statement on the Investigation into the Destruction of Videotapes by CIA Personnel

“In January 2008, Attorney General Michael Mukasey appointed Assistant United States Attorney John Durham to investigate the destruction by CIA personnel of videotapes of detainee interrogations," said Matthew Miller, Director, Office of Public Affairs.



  • OPA Press Releases