Of four genotypes of Encephalitozoon cuniculi, E. cuniculi genotype II is considered to represent a parasite that occurs in many host species in a latent asymptomatic form, whereas E. cuniculi genotype III seems to be more aggressive, and infections caused by this strain can lead to the death of even immunocompetent hosts. Although albendazole has been considered suitable for treatment of Encephalitozoon species, its failure in control of E. cuniculi genotype III infection has been reported. This study determined the effect of a 100x recommended daily dose of albendazole on an Encephalitozoon cuniculi genotype III course of infection in immunocompetent and immunodeficient mice and compared the results with those from experiments performed with a lower dose of albendazole and E. cuniculi genotype II. The administration of the regular dose of abendazole during the acute phase of infection reduced the number of affected organs in all strains of mice and absolute counts of spores in screened organs. However, the effect on genotype III was minor. Surprisingly, no substantial effect was recorded after the use of a 100x dose of albendazole, with larger reductions seen only in the number of affected organs and absolute counts of spores in all strains of mice, implying variations in albendazole resistance between these Encephalitozoon cuniculi genotypes. These results imply that differences in the course of infection and the response to treatment depend not only on the immunological status of the host but also on the genotype causing the infection. Understanding how microsporidia survive in hosts despite targeted antimicrosporidial treatment could significantly contribute to research related to human health.

An AI-powered application lets you create real-time deepfakes during video calls, making you appear to be speaking as anyone from Albert Einstein to the Mona Lisa

Sonos has been busy these past few months.

RPG Cast is back, if a little bit lighter. See what one plays when they have three weeks without work. See what happens when THQ...

Some fans think the new album art was released in anticipation of a rumored platinum edition of Glory.

Chandigarh, May 9: Hockey legend Balbir Singh Sr, a triple Olympic gold medallist, has been admitted to a city hospital in critical condition. The 96-year-old was taken to a private hospital from his residence in Sector 36 in Chandigarh, where

The former Oasis star - whose mother Peggy hails from County Mayo in the West of Ireland originally - has revealed he's considered putting

Openly discussing her mental health has also helped Williams understand why she rushed to the altar with Gilbert.

Arc brings a new design and feature set, while the Play:5 is now just the Five.

Welsh mezzo-soprano Katherine Jenkins will stream a concert from an empty Royal Albert Hall on Friday evening, as locked-down Britain marks the 75th anniversary of "Victory in Europe" Day.

Bob Dylan is releasing his first album of new music in eight years following a spurt of creativity from the man regarded as one of the world's most influential songwriters.

Read our live coronavirus updates HERE Coronavirus: The symptoms

More than a century ago, Einstein predicted how much the star's orbit changes, and now the data collected by scientists exactly matches his theory.

"He pushed one of the police officers on the ground and I think he was about to lunge at another one of the police with the knife, that's what it looked like to me.

Thousands have tuned in to watch Katherine Jenkins' stunning performance in front of an empty Royal Albert Hall as she marked the 75th anniversary of VE Day.

Tomorrow marks 75 since the nation celebrated VE day - the end of fighting against Nazi Germany in Europe.

His biblical performance will be yours to own on 12th June...

For years I have been warning that hatred kills. Like it did in Orlando last Sunday. Or like it did in Britain last Thursday. When the gentle, decent Labour MP Jo Cox was shot and stabbed to death by a another cowardly bigot. And I've also warned that the same poison was spreading in Canada. Where [...]

Team owners have long discussed shortening the draft from its usual 40 rounds, and it was expected to be a point of discussion heading into the winter 2021 expiration of the labor agreement between the league and players' union.

UK population is suffering from 'high levels of psychological distress', according to the research

What’s hot and what’s not in fashion this week

Kaia As in Gerber, who joins the likes of Alexa and Jane Birkin – she now has a bag named after her, by Saint Laurent. Style icon status: confirmed.

There is no time like the present to get creative. Photographer Stephanie Girard is normally bustling about on the set of different photoshoots across Los Angeles but with the ongoing...

Drake dropped a surprise 14-track mixtape and announced his next studio album will be released this summer.

Major League Baseball will cut its amateur draft from 40 rounds to five this year, a move that figures to save teams about $30 million US, a person familiar with the decision told The Associated Press.

A small Alberta town’s attempt to discourage geese from too getting comfortable there took flight about six weeks ago, but it’s getting mixed reviews and ruffling some feathers.

Alberta's use of a smartphone app to help slow the spread of the coronavirus may provide other provinces with insight on what to do — and what to avoid — as Canada begins easing restrictions, heightening the need for effective contact tracing.

A small flock of shorebirds contaminated with oil after touching down on a northern Alberta tailings pond is expected to be released back into the wild within a week.

Specialist London hospital receives working medical equipment used in BBC drama

Actor was ridiculed for remarks as people pointed out they were unlikely to forget current predicament anytime soon

Many people have reported experiencing more dreams than usual during lockdown

Trump took time away from coronavirus crisis to call Kimmel 'wacko' in a social media rant

(Matador)
Will Toledo’s alt-rockers have emerged out of lo-fi fuzz, but seem unsure of where to turn as they drift toward the mainstream

Anyone wondering how things have changed in the world of lauded US alt-rockers Car Seat Headrest might consider the four years that separate Making a Door Less Open from their last album of new material. Ordinarily there would be nothing unusual about that gap – but in the first four years of Car Seat Headrest’s existence, its mastermind, Will Toledo, released seven albums (one of them a two-hour double), four EPs (one of them as long as an album) and two compilations of outtakes. That’s more than 150 songs and 12 hours of music: a lo-fi spewing forth of ideas that won Toledo a cult following, which then grew exponentially, both in size and rabidity, when he recruited a band and signed to the august US indie label Matador.

Nicholas David Weston found guilty of four counts of rape of 19-year-old woman during her 2017 stay at his city apartment

An Airbnb superhost has been jailed for raping a young woman in Melbourne while she was visiting the city with her friend.

Nicholas David Weston was found guilty of four counts of rape of the 19-year-old woman over the horror stay at his Melbourne CBD apartment in November 2017.

The Queen of Pop shared the picture on Instagram

The actor and his wife Sabrina both tested positive for Covid-19 last month

Taylor Swift has reignited a feud with her former record label, accusing it of "shameless greed" over a plan to release a live album she has not authorised.

Katherine Jenkins will sing at an empty Royal Albert Hall tomorrow in a concert being streamed online

Constructed from renewable natural materials like eucalyptus tree fibre, Merino wool and sugarcane, could this be the sneaker to make our running more sustainable?

The Hello hitmaker is celebrating her 32nd birthday

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There is no time like the present to get creative. Photographer Stephanie Girard is normally bustling about on the set of different photoshoots across Los Angeles but with the ongoing...

Major pork plant closed after hundreds of workers contract coronavirus, while speeding up of poultry production lines raises concerns over standards

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The US government is accelerating controversial regulatory rollbacks to speed up production at meat plants, as companies express growing alarm at the impact of Covid-19 on their operations.

Last week Smithfield shut down one of the largest pork plants in the country after hundreds of employees contracted the coronavirus. The plant in South Dakota – whose output represents 4–5% of US pork production – is reported to be the largest single-source coronavirus hotspot in the US, with more than 600 cases. In response, the company said it was “critical” for the meat industry to “continue to operate unabated”.

Now it has emerged that as a wave of plants announce closures, US meat plants are being granted permission to increase the speed of their production lines. This comes despite warnings that the waivers for higher speeds on slaughter and processing lines will compromise food safety.

The Wanderers earn a valuable three points their second win in as many matches with the highlight a Keanu Baccus stunner in the 54th minute at Docklands.

The Sky Blues make it two from two with a against the Phoenix, following Melbourne City's 2-1 win over Adelaide United.

Three men, including two sons of a prominent Melbourne barrister, are sentenced to jail for a drunken attack on two men near the MCG after an AFL game. But at least one of the men could still avoid prison after appealing his sentence and being granted bail.

Michael McCormack told the ABC the demonstrators were merely craving media attention.

In Sydney to open the International Women's Jazz Festival, Wilma Reading toured the world during the genre's golden age but the "icon and trailblazer" is almost unknown in her home country.

Western United come away with a 3-2 win in their Melbourne derby against the Victory despite trailing 2-0 after just seven minutes. Look back at that remarkable win and Western Sydney's 0-0 draw with Brisbane in our ScoreCentre.

She credits her fitness to one lifestyle change.

With the league on pause, The Great One seems to be singularly keeping the league’s news-flow going. This Mailbag owes a great deal to No. 99 as well.