for Heparin-stabilized gold nanoparticles embedded in graphene for the electrochemical determination of esculetin By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2256-2266DOI: 10.1039/D4AY00229F, PaperVinicius José da Silva, Luan Gabriel Baumgarten, Juliana Priscila Dreyer, Edson Roberto Santana, Almir Spinelli, João Paulo Winiarski, Iolanda Cruz VieiraA conductive nanocomposite consisting of heparin-stabilized gold nanoparticles embedded in graphene was prepared for esculetin determination in tea and jam samples.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A pH-response-based fluorescent probe for detecting the mitophagy process by tracing changes in colocalization coefficients By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2241-2247DOI: 10.1039/D4AY00211C, PaperNongyi Hao, Zekun Jiang, Lina Zhou, Xiaoyu Dai, Xiuqi KongA novel pH-response fluorescent probe MP for the detection of mitophagy process via tracing colocalization coeffcients was developed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Construction of a stable fluorescent sensor based on CsPbBr3/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2267-2277DOI: 10.1039/D4AY00032C, PaperYang He, Yangjie Li, Han Wang, Site Luo, Haihu YuConstruction of a stable fluorescent sensor based on CsPbBr3/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol via a mechanism integrating photoinduced electron transfer.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Phenylboronic acid modification-based novel dumbbell-shaped Au–Ag nanorod SERS substrates for ultrasensitive detection of SO42− By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2311-2321DOI: 10.1039/D3AY01831H, PaperKang Shen, Caili Bi, Haifan Yang, Miaowen Xu, Lili Huang, Youwei WangBased on the coordination principle of Lewis acids, a novel 4-MPBA-modified dumbbell-shaped Au–Ag nanorod (4-MPBA@DS Au–AgNR) SERS substrate was developed to realize the high sensitivity and specificity of SO42− detection.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Characterizing a visual lateral flow device for rapid SARS-CoV-2 virus protein detection: pre-clinical and system assessment By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D3AY02075D, PaperNatpapas Wiriyachaiporn, Jetnapang Kongrueng, Kannika Sukkuea, Rattana Tanrattanawong, Jarunee Vanichtanankul, Thanaya Saeyang, Tararat Jantra, Deanpen Japrung, Weerakanya Maneeprakorn, Suwussa Bamrungsap, Pareena Janchompoo, Ekawat PasomsubAnalytical and pre-clinical evaluation of a visual screening lateral flow device for SARS-CoV-2 virus protein detection and its system characterization.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A complementary method with PFBBr-derivatization based on a GC-EI-MS platform for the simultaneous quantitation of short-, medium- and long-chain fatty acids in murine plasma and feces samples By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2330-2339DOI: 10.1039/D3AY02271D, PaperHong-Xu Zhou, Qing Jiang, Xin He, Xian Fu, Jun-Yan LiuFatty acids (FAs) are essential molecules in all organisms and are involved in various physiological and pathophysiological processes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Dual-functional porphyrinic zirconium-based metal–organic framework for the fluorescent sensing of histidine enantiomers and Hg2+ By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2386-2399DOI: 10.1039/D3AY02241B, PaperShili Qin, Fanshu Meng, Fenglong Jin, Xidi Xu, Ming Zhao, Hongtao Chu, Lidi Gao, Shuren LiuL-Cys/PCN-222 as a novel and dual-functional fluorescent sensor was developed. It not only showed a higher chiral fluorescent recognition of L-histidine but also performed as a visual sensor for Hg2+ in actual surface water.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Construction of coumarin-appended calix[4]arene-based fluorescence sensor for the detection of carbofuran in cabbage By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2400-2411DOI: 10.1039/D4AY00030G, PaperHeni Soni, Nidhi Verma, Divyesh Y. Chaudhari, Sahaj A. Gandhi, Alok Pandya, Pinkesh G. SutariyaThis study presents a novel approach for the detection of carbofuran (CBF) insecticide by exploring a calix[4]arene-derived fluorescence probe, CouC4S, functionalized with two coumarin-labelled at the narrow edge of the calix[4]arene platform.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for On-chip light sheet illumination for nanoparticle tracking in microfluidic channels By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2229-2240DOI: 10.1039/D3AY02290K, CommunicationThéo Travers, Gaétan Delhaye, Martinus H. V. Werts, Denis Gindre, Matthieu LoumaigneA simple and inexpensive method is presented to efficiently integrate light sheet illumination in a microfluidic chip for dark-field microscopic tracking and sizing of nanoparticles.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A chemiluminescence immunoassay for type IV collagen as a promising marker for liver fibrosis and cirrhosis By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2248-2255DOI: 10.1039/D3AY02240D, PaperXiaoling Fu, Fan Zhang, Fangda Zhen, Lian Duan, Jian Zhou, Jianguo MaHerein, a magnetic bead-based chemiluminescence assay is reported to detect type IV collagen (col-IV) in serum samples.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for An overview of electrochemical biosensors used for COVID-19 detection By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2164-2176DOI: 10.1039/D3AY02042H, MinireviewTatiana Lima Valerio, Raquel Anastácio, Stella Schuster da Silva, Carolina Camargo de Oliveira, Marcio VidottiThis short review presents the latest advances in the field of electrochemical biosensors, focusing particularly on impedimetric biosensors for the direct measurement of analytes.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A new colorimetric aptasensor for paraquat detection based on the designed aptamer with multiple paraquat binding sites in combination with gold nanoparticles By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2340-2348DOI: 10.1039/D4AY00053F, PaperPakawat Kongpreecha, Sineenat SiriGiven paraquat's environmental health risks, there is a need for a fast and simple detection method. This study presents a novel colorimetric aptasensor with a tailored aptamer, boosting sensitivity by targeting multiple paraquat binding sites.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for An immunochromatographic strip sensor for rapid and sensitive detection of candesartan, olmesartan medoxomil, and irbesartan in herbal beverages By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2359-2367DOI: 10.1039/D4AY00151F, PaperDingyu Li, Aihong Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu, Xiaoling WuSartans, as a class of antihypertensive drugs, pose a threat to human health when illegally added to herbal beverages.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A novel electrophoretic assisted hydrophobic microdevice for enhancing blood cell sorting: design and numerical simulation By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2368-2377DOI: 10.1039/D4AY00196F, PaperXinkun Chen, Xueye ChenMicrofluidic technology has great advantages in the precise manipulation of micro–nano particles, and the hybrid microfluidic separation technology has attracted much attention due to the advantages of both active and passive separation technology at the same time.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00146J, PaperDumei Ma, Yiting Luo, Xiaoya Zhang, Zehu Xie, Yinghua Yan, Chuan-Fan DingA fluorescence method based on Cu-triggered click reaction of azide modified CD63 aptamer and alkyne capped Pdots was developed for breast cancer derived exosome detection.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Analysis of brominide disinfection by-products in aquaculture water using ultra-high-performance liquid chromatography–quadrupole–time-of-flight mass spectrometry By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00396A, PaperWeimin Yang, Yi Zhang, Jilong Huang, Xing Yang, Ning JiangBackground: Halogenic disinfectants have been shown to produce toxic and carcinogenic disinfection by-products (DBPs) during water disinfection. Dibromohydantoin (DBDMH) is a commonly used water disinfectant in aquaculture. Aquaculture water has...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Paper-based sensors: affordable, versatile, and emerging analyte detection platforms By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D3AY02258G, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Sumit Malik, Joginder Singh, Kajal Saini, Vivek Chaudhary, Ahmad Umar, Ahmed A. Ibrahim, Sheikh Akbar, Sotirios BaskoutasThe schematic representation of distance based paper sensor to identify lead in food samples.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Simple fluorescence “turn-off” assay for Congo red using commercial 2-aminophthalic acid By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00506F, PaperJiaqi Qian, Jie Li, Yihan Jiang, Chaoyong Liu, Jiayao Zhu, Liyu Gu, Yongming Guo2-Aminophthalic acid with a high quantum yield of 38.49% was utilized for fluorescence “turn-off” sensing of Congo red with a linear range of 0.05–50 μM and a limit of detection of 1.72 μM.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A reaction based carbazole–indolium conjugate probe for the selective detection of environmentally toxic ions By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00301B, PaperJayasudha Palanisamy, Mansour K. Gatasheh, Ashraf Atef HatamlehCarbazole–indolium based colorimetric probe was designed for detecting cyanide ions in various water samples. An outstanding response was shown by paper test strips prepared using the probe for the easy detection of cyanide in real time.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Polymeric membrane potentiometric sensors based on template-removal-free imprinted receptors for determination of antibiotics By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00263F, PaperXinyao Wang, Guohua Cui, Rongning Liang, Wei QinCurrently, Nernstian-response-based polymeric membrane potentiometric sensors using the molecularly imprinted polymers (MIPs) as the receptors have been successfully developed for determination of organic ionic species. However, the preparation of these...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00487F, PaperJinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang LiuSmall extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Design and fabrication of La-based perovskites incorporated with functionalized carbon nanofibers for the electrochemical detection of roxarsone in water and food samples By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00264D, PaperMariya Antony John Felix, Santhiyagu Sahayaraj Rex Shanlee, Shen-Ming Chen, Sundaresan Ruspika, Ramachandran Balaji, Narendhar Chandrasekar, Periyanayagam Arockia DossFabrication of potent electrocatalyst, La-based perovskites coupled with functionalized carbon nanofibers (LMO/f-CNF) for ultrasensitive electrochemical detection of roxarsone in edible and water samples.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for The preparation of a boronate affinity-based controlled oriented imprinting coating on a silica nanoparticle surface for the separation and purification of shikimic acid in herbal medicine By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00219A, PaperYumin Yang, Daojin Li, Bingqian LiuShikimic acid (SA) is one of the most effective drugs against the A (H1N1) virus and has high medicinal value.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Α simplified lateral flow immunosensor for the assay of carcinoembryonic antigen in low-resource settings By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00381K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ioanna Tsogka, Electra Mermiga, Varvara Pagkali, Christos Kokkinos, Anastasios EconomouCarcinoembryonic antigen (CEA) is a glycoprotein widely used as a tumor marker. In this work, a colorimetric lateral flow immunosensor is developed for rapid and low-cost quantification of CEA in...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A chemodosimetric chemosensor for the ratiometric detection of nerve agent-mimic DCP in solution and vapor phases By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00451E, PaperShilpita Banerjee, Pintu Ghosh, Anirban Karak, Dipanjan Banik, Ajit Kumar MahapatraThe probe MNFZ undergoes a hydrolysis reaction in the presence of DCP to exhibit a naked eye color change from blue to cyan. It was successfully applied to sense DCP in the vapor phase.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Three-dimensional hotspot structures constructed from nanoporous gold with a V-cavity and gold nanoparticles for surface-enhanced Raman scattering By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00348A, PaperYang Xu, Yan Wu, Jianjun Wei, Yuanyu Zhao, Peili XueA nanoporous gold V-shaped resonant cavity (NPGVRC) structure constructed with plasmonic resonance coupling effect. The NPGVRC has excellent SERS performance and 3D hotspot properties.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Monolith stationary phases prepared via cyclic anhydride ring-opening polymerization as tunable platforms for chromatographic applications By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00251B, PaperAhmad Aqel, Ayman Ghafr, A. Yacine Badjah-Hadj-Ahmed, Zeid Abdullah ALOthmanPolymer monolithic stationary phases were prepared based on a cyclic anhydride as a reactive and tunable platform via ring-opening post-polymerization using primary amines; octadecylamine and benzylamine. The characterization techniques indicated...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A colorimetric tandem combination of CRISPR/Cas12a with dual functional hybridization chain reaction for ultra-sensitive detection of mycobacterium bovis By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D3AY02200E, PaperQiong Liu, Mei Yang, He Zhang, Wenjie Ma, Xin Fu, Huiqing Li, Sainan GaoTuberculosis caused by Mycobacterium bovis poses a global infectious threat to humans and animals. Therefore, there is an urgent need to develop a sensitive, precise, and easy-to-readout strategy. Here, a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Solutions and Tools for Dealing with Broken Links in Web Pages By www.impressivewebs.com Published On :: Tue, 01 Dec 2020 22:19:09 +0000 A couple of months ago a post by Leo Blanchette got to the front page of Hacker News and there was an interesting discussion on dealing with broken links and external content – the main problem being links that become out of date due to paywalls, altered content, or content getting taken down. I’ve been running this blog since May 2008. If you’ve run a content-driven site for even a fraction of that, you know that link rot is a problem. In this post I’ll go over some of the suggestions in that thread along with some tools to use to check for broken links. The post Solutions and Tools for Dealing with Broken Links in Web Pages appeared first on Impressive Webs. Full Article HTML5 Web Design Articles
for Are These the Most Interesting Front-end Developer Tools for 2021? By www.impressivewebs.com Published On :: Tue, 05 Jan 2021 09:47:31 +0000 When I come to the end of any given year, it’s always interesting to look back through the click-through stats for my weekly newsletter Web Tools Weekly to see which tools got the most attention. This year wasn’t all that different from previous years. I’ve learned that clicks happen for basically one of two reasons: The post Are These the Most Interesting Front-end Developer Tools for 2021? appeared first on Impressive Webs. Full Article Roundups and Resources
for A Review of ipwhois.io for Reliable Geolocation Data By www.impressivewebs.com Published On :: Mon, 07 Feb 2022 11:00:00 +0000 [Sponsored] If you’re building an app that requires delivering a dynamic experience based on the user’s location or other location-related data, a fast and easy-to-use Geolocation API will certainly come in handy. One such option is ipwhois.io. The service, which is free for small non-commercial projects that need fewer than 10,000 requests per month, is easy to integrate with your tech stack. As usual, it’s always best to look at a few examples so you can see it in action. Their documentation is short and easy to follow, so I’ll demonstrate using the following example request: The post A Review of ipwhois.io for Reliable Geolocation Data appeared first on Impressive Webs. Full Article Sponsored
for Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content By www.impressivewebs.com Published On :: Wed, 11 May 2022 10:00:00 +0000 [Sponsored] If you’re building an app that requires a lot of user-generated content and media that needs to be processed, tagged, filtered, or otherwise manipulated in real-time, you definitely want a solution that’s fast and seamless and doesn’t get in the way of your app’s primary functionality. Filestack is a service you’ll want to consider. Here’s what Filestack offers: The post Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content appeared first on Impressive Webs. Full Article Sponsored Web Design Articles
for YouTube’s Time-Based UX Problem for Live Sports By www.impressivewebs.com Published On :: Mon, 30 Sep 2024 10:00:00 +0000 I like to play beach volleyball here in the Toronto area. I also watch beach volleyball on YouTube, which includes a lot of live streams from the AVP league in the US. It's a fun sport that I recommend to anyone looking for a new athletic competition to follow. In most leagues and tournaments, beach volleyball games have a 3-set format, with each set finishing when a team reaches 21 points (or higher if they're not yet ahead by 2). The third set (played if needed) will go up to 15 points (again, win by 2). Some leagues/tournaments will play all three sets up to 15. It depends on the venue, tournament, etc. The post YouTube’s Time-Based UX Problem for Live Sports appeared first on Impressive Webs. Full Article UX Web Design Articles
for A better Twitter app for Android, at last By www.thehindubusinessline.com Published On :: Fri, 05 Apr 2013 14:05:30 +0530 Full Article R Dinakaran
for QR codes for security in vehicles By www.thehindubusinessline.com Published On :: Tue, 03 Sep 2013 16:32:33 +0530 Full Article R Dinakaran
for The transformation of BSNL By www.thehindubusinessline.com Published On :: Fri, 03 Jan 2014 15:08:58 +0530 Full Article R Dinakaran
for BSNL customer service changing for the better By www.thehindubusinessline.com Published On :: Thu, 09 Jan 2014 15:55:31 +0530 Full Article R Dinakaran
for For a fair probe: On the Kejriwal bail order and CBI conduct By www.thehindu.com Published On :: Mon, 16 Sep 2024 00:47:00 +0530 Kejriwal bail order is a reminder to CBI to dispel perception of bias Full Article Editorial
for Clarity of vision: On eye drops for presbyopia and ‘claims’ By www.thehindu.com Published On :: Tue, 17 Sep 2024 00:15:00 +0530 A useful drug is undone by fantastic claims about its efficacy Full Article Editorial
for A fair share: On the concerns of high performing States By www.thehindu.com Published On :: Thu, 19 Sep 2024 00:10:00 +0530 The Sixteenth Finance Commission must address the concerns of high-performing States Full Article Editorial
for Delay and bail: On former Tamil Nadu Minister V. Senthilbalaji’s case By www.thehindu.com Published On :: Sat, 28 Sep 2024 00:20:00 +0530 Senthilbalaji’s release on bail was overdue, but he should not be made a Minister Full Article Editorial
for Steady but slow: On the VIPER mission, lessons for India By www.thehindu.com Published On :: Tue, 01 Oct 2024 00:30:00 +0530 India’s space programme needs more resources to realise its full potential Full Article Editorial
for A defeat foretold: On the Maoist insurgency By www.thehindu.com Published On :: Mon, 07 Oct 2024 00:30:00 +0530 Maoists must abandon armed struggle and enter the democratic process Full Article Editorial
for Biology transformed: On the Nobel Prize in chemistry By www.thehindu.com Published On :: Mon, 14 Oct 2024 00:28:00 +0530 Nobel for determining protein structure recognises a big advance Full Article Editorial
for Allow for deliberation: On the legitimate demands of Ladakh By www.thehindu.com Published On :: Tue, 22 Oct 2024 00:15:00 +0530 The lack of a legislature and regional autonomy in Ladakh has led to the current protests Full Article Editorial
for Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3395-3417DOI: 10.1039/D4MD00334A, Research ArticleVu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh ThanhD-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3495-3506DOI: 10.1039/D4MD00275J, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. RussellThe optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3433-3443DOI: 10.1039/D4MD00468J, Research ArticleMeijuan Liu, Na Li, Zhaoxue Wang, Shuo Wang, Shaoda Ren, Xiaojing LiA synthetic celastrol derivative (Cel-N) attenuates cancer cell stemness, inhibits the STAT3 pathway, and exerts anti-ovarian cancer effects in cell and mouse models.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00517A, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Arianna Amenta, Susanna Comi, Marcelo Kravicz, Silvia Sesana, Antonia Antoniou, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca ReA novel, glutathione-activated prodrug of pimasertib (PROPIMA) has been developed. PROPIMA showed ability to inhibit tumour cell migration and proliferation controlled over time, while also achieving a high incorporation rate into liposomes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
for Modulating polybasic character of galactose-based glycosylated antitumor ether lipids for enhanced cytotoxic response By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00662C, Research ArticleRajat Arora, Ayan Mukherjee, Gilbert Arthur, Mark W. Nachtigal, Frank SchweizerWe describe the multi-step synthesis of different dibasic and tribasic galactosamine-based glycosylated antitumor ether lipids (GAELs) and their cytotoxic response in comparison to doxorubicin and cisplatin.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article