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Tailoring of novel morpholine-sulphonamide linked thiazole moiety as dual targeting DHFR/DNA gyrase inhibitors: Synthesis, antimicrobial, antibiofilm activities and DFT with molecular modelling studies

New J. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D3NJ05774G, Paper
Moaz M. Abdou, Essam Eliwa, Mohamed Abdel Reheim, Ahmed Abu-Rayyan, Shimaa M. Abd El-Gilil, Mohammed Abu-Elghait , Mohamed H. Sharaf, Mohamed Kalaba, Ahmed Halawa, Walid Elgammal
Herein, the chemical synthesis of new thiazoles-based benzenesulfonamide-linked morpholine 4a,b–7 via late-stage thiazolation of the corresponding thiosemicarbazone 3 was reported. The skeletal formulas of the new compounds were confirmed by...
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Preparation of hydrogels with self-reinforced mechanical properties using ball-milled microcrystalline cellulose and regenerated cellulose from deep eutectic solvent

New J. Chem., 2024, 48,7405-7412
DOI: 10.1039/D4NJ00622D, Paper
Yi Zhang, Yingming Zhu, Kejing Wu, Yingying Liu, Houfang Lu, Bin Liang
Choline chloride–lactic acid deep eutectic solvent assisted by ball milling effectively dissolved microcrystalline cellulose. Regenerated cellulose was used to prepare novel cellulose hydrogel with self-reinforced mechanical properties.
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Highly crystalline graphite nanofibers as an anode for high-performance potassium-ion batteries

New J. Chem., 2024, 48,7497-7502
DOI: 10.1039/D4NJ00662C, Paper
Kaixuan Sun, Kun Chang, Jinshuo Tan, Chuan-Fu Sun, Qin Liu
Graphite nanofibres with high crystallinity and low defect levels for potassium-ion batteries with high initial Coulombic efficiency and long cycling stability are reported in this study.
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Construction of NiCo2S4−xPx nanowire arrays for efficient hydrogen evolution reactions in both acidic and alkaline media

New J. Chem., 2024, Advance Article
DOI: 10.1039/D4NJ00361F, Paper
Guanglei Liu, Yutong Feng, Yifan Yang, Yuan Wang, Huixiang Liu, Can Li, Mingxin Ye, Jianfeng Shen
Construction of NiCo2S4−xPx nanowire arrays for improved HER performances in both acidic and alkaline media.
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Oxazoline amino acid bioconjugates: one-pot synthesis and analysis of supramolecular interactions

New J. Chem., 2024, Advance Article
DOI: 10.1039/D4NJ00995A, Paper
Marija Bakija, Berislav Perić, Srećko I. Kirin
Oxazoline amino acid bioconjugates were synthesized; the relative stability of a supramolecular dimer of a tris-derivative was investigated using mean absolute error values (MAE), derived from 1H NMR experiments and DFT calculations.
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Influence of the secondary ligand, phenanthroline, on the antioxidant and pro-oxidant and cytotoxic effects of the oxidovanadium(IV)/naringin complex

New J. Chem., 2024, Advance Article
DOI: 10.1039/D4NJ00655K, Paper
Andrés G. Restrepo, Angel L. Huamani, Alexandra Velásquez Bravo, Pablo J. González, Luciana G. Naso, Evelina G. Ferrer, Patricia A. M. Williams
Replacement of phen in [VO(Narg)2] induces greater π electronic delocalization, thus improving antioxidant action. However, due to its lipophilic character, cellular uptake of V is increased, leading to enhanced pro-oxidant and anticancer effects.
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Evaluation of adsorption and degradation performance of lanthanum modified mesoporous carbon nitride composite materials for tetracycline wastewater

New J. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4NJ00864B, Paper
Zhiqiang Wu, Yueyi Li, Pengxi Jiang, Sisi Ma, Wenfei Dong, Hongjian Zhao, Enke Feng, Xuming Wang
The lanthanum modified mesoporous graphite nitride carbon composites (La-g-C3N4) were synthesized using a thermal shrinkage polymerization method. The samples underwent characterization through the X-ray diffraction (XRD), the fourier transform infrared...
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Self-Sacrificial templated-directed synthesis of ultrathin 0D/2D FeNi3-NC/NiFeOx Schottky junction as hydrogen evolution reaction electrode for alkaline seawater electrolysis

New J. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4NJ01321B, Paper
Zili Xu, Yuankang Bao, Xun Xu, Ping Li, Hao Zhang, Deliang Li, Shuwang Duo
Seawater, a plentiful natural resource, is promising for hydrogen production compared to traditional electrocatalytic methods based on high-purity freshwater. This strategy shift addresses the challenge of limited freshwater resources and...
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Toys assured to take children offline

Bhuvaneshwari Kumaravel has created eco-friendly traditional toys that keep children and adults engaged




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A novel CuAl2O4/MoS2/BaFe12O19 magnetic photocatalyst simultaneously coupling type I and Z-scheme heterojunctions for the sunlight-driven removal of tetracycline hydrochloride

Environ. Sci.: Nano, 2024, Advance Article
DOI: 10.1039/D3EN00970J, Paper
Mengjun Han, Shifa Wang, Xinmiao Yu, Xianlun Yu, Huajing Gao, Xianju Zhou, Dengfeng Li, Leiming Fang, Jagadeesha Angadi V., Mohd Ubaidullah, Bidhan Pandit
A novel CuAl2O4/MoS2/BaFe12O19 photocatalyst is synthesized that simultaneously couples type I and Z-scheme heterojunctions and exhibits high photocatalytic activity for the degradation of TC under simulated sunlight irradiation.
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Biogenic synthesis of dual-emission chlorophyll-rich carbon quantum dots for detection of toxic heavy metal ions – Hg(II) and As(III) in water and mouse fibroblast cell line NIH-3T3

Environ. Sci.: Nano, 2024, 11,1636-1653
DOI: 10.1039/D3EN00789H, Paper
Ravi Pratap, Nurul Hassan, Monika Yadav, Saurabh Kumar Srivastava, Shilpi Chaudhary, Anita Kamra Verma, Jayeeta Lahiri, Avanish S. Parmar
Due to the excessive residues and serious adverse effects, it is urgent to develop an efficient method to detect Hg2+ and As3+ in drinking water to protect human health.
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Macro- and micro-structural manifestation and engineering of large-size polycrystalline ZnSe

CrystEngComm, 2024, 26,1986-1993
DOI: 10.1039/D3CE01243C, Paper
Xiaobo Zhao, Cong Zhang, Zhengping Wang, Dazhi Lu, Haohai Yu, Huaijin Zhang
Polycrystalline ZnSe materials with sizes of 100 mm were grown by the CVD method, and their constitution structures and defects were investigated to analyze the influence of the preparation conditions on the optical transmission properties of the materials.
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Co-doped modified LiLuF4:Eu microcrystalline scintillation with flexible film for high resolution X-ray imaging

CrystEngComm, 2024, Accepted Manuscript
DOI: 10.1039/D4CE00211C, Paper
Xixi Huang, Jinhai Yang, Hao Lu, Xieming Xu, Shuaihua Wang, Shaofan Wu
X-ray detectors based on scintillators are widely used in the fields of medical imaging, high-energy physics, geological exploration, and industrial detection. The development of scintillation materials with different characteristics has...
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New 8-hydroxy quinoline-polycyclic aromatic hydrocarbon (PAH) conjugates and their sulfonated derivatives: effects of sulfonation and PAH size on their structural, supramolecular and cytotoxic properties

CrystEngComm, 2024, Advance Article
DOI: 10.1039/D4CE00105B, Paper
Suman Sehlangia, Surbhi Dogra, Prosenjit Mondal, Chullikkattil P. Pradeep
The ring size of polycyclic aromatic hydrocarbons (PAHs) and sulfonation affect the supramolecular interactions and cytotoxic properties of a new series of 8-hydroxy quinoline-PAH conjugates.
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Degradation of tetracycline by visible light using Ca2Nb2O7 composite oxides with perovskite and pyrochlore sub-crystalline phases

CrystEngComm, 2024, Advance Article
DOI: 10.1039/D4CE00044G, Paper
Junwei Xu, Chengxin Lu, Xianfeng Zhang, Rumeng Ouyang, Xiuzhong Fang, Xianglan Xu, Xiang Wang
We synthesized two paramorphs of Ca2Nb2O7 for visible light degradation of tetracycline, and found that pyrochlore phase has better reactivity compared to perovskite phase, which is attributed to the intrinsic oxygen vacancies and lattice disorder of pyrochlore phase.
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Centre extends deadline for Telangana millers for supply of rice to FCI

Asks State government to adhere to quality norms




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Outstanding power sector dues of States decline by ₹24,680 crore

It is expected that strict implementation of the LPS rules will bring back financial viability of the power sector in the country and would attract investment to ensure reliable 24x7 electricity to the consumers




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Civil Aviation Ministry notifies operational guidelines for drone PLI scheme

The PLI scheme will be only for the companies that are involved in the manufacture of drone and drone components in India




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Government amends rules to place online gaming under MeitY

The appointment of MeitY as the central regulatory authority will provide clarity and certainty to investors, industry and consumers, says Federation of Indian Fantasy Sports




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Car sales declined by 7% in December

But utility vehicle segment grew 23% year-on-year: SIAM data




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Global steel output declines 2.4% in April as China disappoints

Indian steel production up a notch year-on-year but lower than March output




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Wholesale inflation declines to 90-month low of -3.48% in May

WPI inflation trend to help retail inflation nearing RBI MPC’s target of 4%




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At the end of the line

The women of Nochi Kuppam more than add to the character of this coastal stretch. They keep the home fires burning




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FSSAI looking to develop SOP for online food deliveries for quick commerce, e-commerce platforms

The SOP will look at elaborating on parameters to ensure compliance with food safety norms across the entire supply chain of online food delievery ecosystem




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Salman Khan gets another threat; message sent to Mumbai traffic police helpline

In the past few weeks, the traffic police helpline has received many threat messages for Salman Khan.




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Jacqueline's Dreamy Beach Vacation

What's a vacation if you don't post some super hot pictures on your social media feed soon after?





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EndNote Parts 1 & 2 (Combined) Workshop Online | Nov. 13

Link to Notice




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Gujarat CM Patel calls on citizens to ensure Vadodara leads in cleanliness




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How to Set Date Time from Mac Command Line

Working on a web extension that ships to an app store and isn’t immediately modifiable, like a website, can be difficult. Since you cannot immediately deploy updates, you sometimes need to bake in hardcoded date-based logic. Testing future dates can be difficult if you don’t know how to quickly change the date on your local […]

The post How to Set Date Time from Mac Command Line appeared first on David Walsh Blog.




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Indian online gaming sector faces money laundering threat, warns report

The sector employs around one lakh people and has the potential to to create 2,50,000 jobs by 2025




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Making a beeline

Does a beeline refer to a formation of bees? Or is there more to it?




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Coumarin–azasugar–benzyl conjugates as non-neurotoxic dual inhibitors of butyrylcholinesterase and cancer cell growth

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00312H, Paper
I. Caroline Vaaland Holmgard, Aday González-Bakker, Eleonora Poeta, Adrián Puerta, Miguel X. Fernandes, Barbara Monti, José G. Fernández-Bolaños, José M. Padrón, Óscar López, Emil Lindbäck
Coumarin–azasugar–benzyl conjugates were obtained through the CuAAC reaction, displaying dual anti-Alzheimer and anti-cancer activity in vitro and no neurotoxicity.
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Diastereoselective synthesis of functionalized spiroindolines via intramolecular ipso-iodocyclization/nucleophile addition cascade reactions of indole-tethered ynones

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00112E, Paper
Debojyoti Bag, Sanghapal D. Sawant
Herein, we describe a highly diastereoselective approach for synthesizing polyfunctionalized spiroindolines from indolyl-ynones involving an ipso-iodocyclization/nucleophile addition cascade.
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HFIP-mediated C-3-alkylation of indoles and synthesis of indolo[2,3-b]quinolines & related natural products

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00414K, Paper
Auqib Rashid, Waseem I. Lone, Preeti Dogra, Showkat Rashid, Bilal A. Bhat
An expeditious metal free C-3 alkylation of indoles and its NIS-mediated deviation to indolo[2,3-b]quinolines is reported. Applications of these strategies in accessing bioactive natural products have also been demonstrated.
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Design, synthesis, biological evaluation and molecular docking studies of quinoline-anthranilic acid hybrids as potent anti-inflammatory drugs

Org. Biomol. Chem., 2024, Advance Article
DOI: 10.1039/D4OB00040D, Paper
Sidra Siddique, Khalid Hussain, Naureen Shehzadi, Muhammad Arshad, Muhammad Nadeem Arshad, Sadaf Iftikhar, Farhat Saghir, Ayisha Shaukat, Muhammad Sarfraz, Nisar Ahmed
Despite the high global prevalence, rheumatoid arthritis lacks a satisfactory treatment.
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Facile synthesis of tetrahydroquinoline containing dithiocarbamate derivatives via one-pot sequential multicomponent reaction

Org. Biomol. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4OB00490F, Communication
SIDDHARTHA KUMAR SENAPATI, Anit Pal, Animesh Das
An efficient sequential multi-component method for the synthesis of tertrahydroquinoline containing dithiocarbamate has been developed. This reaction involved a boronic acid-catalyzed reduction of quinoline to tertrahydroquinoline, followed by nucleophilic addition...
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Wanted: A booster dose for airlines

As vaccination numbers increase, airlines and the government look for the middle path to revive the beleagured travel sector




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Year-end blues for beleagued airlines

The results of IndiGo and SpiceJet hold clues to the mid-term future of the country’s airline industry




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As the price of aviation turbine fuel soars, airlines’ finances spin out of control




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Regional airlines fly into rough weather

From poor applicability of policy to lack of quality manpower and capital, problems plaguing them are manifold




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The making of ‘agile’ airlines

How adoption of AI, ML can empower flying




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Domestic air travel leads airline recovery: Boeing

Low-cost carriers aid market with point-to-point structure and affordable rates




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Reskilling of airline workforce needed

Industry grapples with skilling/reskilling employees right from pilots to ground handling staff whose skills may be redundant




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Omicron: Airlines on a wing and prayer

Over 3,000 flights were cancelled on the eve of Christmas and cancellations are expected to double as New Year approaches




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2022 holds promise for the airline sector

Omicron might dent growth, but the long-term outlook seems promising




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Robust flight plans can keep airlines afloat




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Deep tech is helping airlines sustain operations during Covid

Integrated biometric-enabled frameworks for real-time test results, travel details and vaccine status are key to making air travel safe




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Breaking down airline engineering and maintenance

An aircraft has three critical phases; induction, in-service and redelivery




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Another tough year for airlines

Ukraine-Russia conflict to result in the steep escalation of aircraft leasing charges