The North brand GX-8 series of safety eyewear is semi-frameless and features sleek, nickel-free, brushed steel frames for a sophisticated look and 8-base wraparound lenses for optimum coverage and protection.

PANOS brands, LLC, a provider of branded consumer foods, announced that it has acquired certain assets of Tessemae's LLC, including the Salad Dressings & Condiments Business. Tessemae's is a leading brand in refrigerated and shelf stable organic salad dressings.

Consumers have long shown a reluctance to purchase food containing artificial preservatives, with research finding that 57% globally prefer products that are free from additives and 62% are concerned about ingredients that sound chemical.  

The SmartLoad FramePro 751XP clipped head framing nailer, SmartLoad FramePro 752XP full round head framing nailer, and SmartLoad SCN65XP coil nailer mount easily to most popular bridge systems, providing dependable fastening performance for machine- driven, high-volume assembly of walls, floors, roofs and other wood construction.

Preferred Flooring President Daniel Gonzalez urges the flooring installation community to follow the right guidelines for semi-wet-setting luxury vinyl.

This is a question for the experienced cruisers. My wife and I have taken many cruises out of San Juan and are planning another on RC this January. Flight options on arrival to the port after the cruise are limited to either early morning (8 am...

TCAA and IMI held the first of the six-event Ceramic Tile Seminar series in New Berlin, Wis.

Children's Geographies; 12/01/2021
(AN 153655055); ISSN: 14733285
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Children's Geographies; 06/01/2022
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Children's Geographies; 05/15/2024
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The post An Introduction to Metascience The Discipline of Evaluating the Creation and Dissemination of Research was curated by information for practice.

Ford-Crawford Hall, Simon Music Center
Thursday, December 5, 2024, 8:30 – 10pm

More info: events.iu.edu…

Auer Hall, Simon Music Center
Thursday, December 5, 2024, 8 – 10pm

Repertoire
Mason Bates: The Rise of Exotic Computing (2013)
Corey Chang: What’s Next? (2024, premiere)*
Sean Shepherd: Simple Machines (2024)

*New Music Ensemble Commission

More info: events.iu.edu…

Buskirk-Chumley Theater
Monday, November 11, 2024, 7:30 – 9:30pm

The Natalie Boeyink Jazz Ensemble will commemorate Veteran’s Day with compositions by those who served. Selections include works by Glenn Miller, John Coltrane, Clark Terry, Wayne Shorter, Horace Silver and more.

Presenter: Indiana University Jacobs School of Music Jazz Studies Department
Contact: BCT Box Office, boxoffice@buskirkchumley.org
Cost: Free!
Ticket Phone: 812-323-3020
Communities: Bloomington
More info: buskirkchumley.org…

Buskirk-Chumley Theater
Monday, November 11, 2024, 7:30 – 9:30pm

More info: events.iu.edu…

Auer Hall, Simon Music Center
Sunday, November 10, 2024, 11am – 12pm

More info: events.iu.edu…

While conducting research at the Auschwitz-Birkenau Memorial and Museum, a music theory professor discovered manuscripts of music that haven't been heard since World War II.

Over 200,000 people canceled their subscriptions in the first few days following news that The Washington Post would not endorse any presidential candidate.

After a recent shooting of a Jewish man on his way to synagogue in Chicago and a surge in antisemitic incidents, a ministry focused on sharing the Gospel with Jewish communities is stepping up to equip Christians with tools to support God’s chosen people.

“In spite of cold weather”: music for winter17th- and 18th-century music for the winter season from England, France, and ItalyDavid H. Miller, directorSafety The UC Berkeley Department of Music is committed to the health and safety of our students, staff, and patrons. Measures to protect concertgoers and musicians will be informed by state, local, and UC Berkeley Public Health policies and are subject to change. Social distancing, masks, and proof of COVID 19 vaccination may be required.Purchasing tickets in advance is highly recommended Social Media Facebook: @ucbmusicdept Instagram: @ucberkeleymusic  Twitter: @ucbmusicdept Youtube: Berkeley Music channel Accessibility If you require an accommodation for effective communication (ASL interpreting/CART captioning, alternative media formats, etc.) or information about campus mobility access features in order to fully participate in this event, please contact the Hertz Hall Manager at 510.642.4864 or hertzhallmgr@berkeley.edu with as much advance notice as possible and at least 7-10 days in advance of the event. PERFORMANCES ARE SUBJECT TO CHANGE WITHOUT NOTICE

Matthew Sadowski, conductorSafety The UC Berkeley Department of Music is committed to the health and safety of our students, staff, and patrons. Measures to protect concertgoers and musicians will be informed by state, local, and UC Berkeley Public Health policies and are subject to change. Social distancing, masks, and proof of COVID 19 vaccination may be required. UC Berkeley does not promise or guarantee that all patrons or employees on site are vaccinated. Unvaccinated individuals may be present as a result of exemptions, exceptions, fraudulent verification, or checker error. None of these precautions eliminate the risk of exposure to COVID-19. Accessibility If you require an accommodation for effective communication (ASL interpreting/CART captioning, alternative media formats, etc.) or information about campus mobility access features in order to fully participate in this event, please contact the Hertz Hall Manager at 510.642.4864 or hertzhallmgr@berkeley.edu. with as much advance notice as possible and at least 7-10 days in advance of the event. Facebook: @ucbmusicdept Instagram: @ucberkeleymusic Twitter @ucbmusicdept Youtube: Berkeley Music YouTube channel

Putin's Annual Address to the Federal Assembly is scheduled for September 30. Kremlin sources say it will become even more historic and globally important than the 2014 address for the return of Crimea. Mass media and experts make their own suggestions about the content of Putin's speech that he is going to deliver to the Federal Assembly on September 30. There are a number of versions:

On Thursday, February 29, Russian President Vladimir Putin delivered his annual Address to the Federal Assembly. In the beginning of the speech, he touched on the topics of the special military operation in Ukraine, relations with the West, strategic stability, and later proceeded to announce a number of new national projects, changes in economic and social sphere. About special military operation Putin recalled that 2024 marks the tenth anniversary of the "legendary Russian Spring.” "The love that the people living in Crimea and new regions share for their homeland evokes pride," Vladimir Putin said.

Health Care Provider Boot Camp Day 8: Billing and Reimbursement Training for Designated Doctor and Other Certifying Doctor Exams

Texas Workers’ Compensation 2025 Professional and Workers’ Compensation Specific Exams Reimbursement Rates

Looking for medical experts to comment on the findings of the following embargoed study: Vitamin D Supplements May Lower Blood Pressure in Older People with Obesity

Looking for medical experts to comment on the findings of the following embargoed study: Vitamin D Supplements May Lower Blood Pressure in Older People with Obesity

[Inter-Korea] :
North Korean troops have reportedly arrived in Russia's Kursk region amid speculations that they are expected to participate in combat against Ukrainian troops, who have occupied a portion of the region since August. Citing one Ukrainian and two American officials, The New York Times said on Friday ...

[more...]

A novel approach to computationally enhance the sampling of molecular crystal structures is proposed and tested. This method is based on the use of extended variables coupled to a Monte Carlo based crystal polymorph generator. Inspired by the established technique of quasi-random sampling of polymorphs using the rigid molecule constraint, this approach represents molecular clusters as extended variables within a thermal reservoir. Polymorph unit-cell variables are generated using pseudo-random sampling. Within this framework, a harmonic coupling between the extended variables and polymorph configurations is established. The extended variables remain fixed during the inner loop dedicated to polymorph sampling, enforcing a stepwise propagation of the extended variables to maintain system exploration. The final processing step results in a polymorph energy landscape, where the raw structures sampled to create the extended variable trajectory are re-optimized without the thermal coupling term. The foundational principles of this approach are described and its effectiveness using both a Metropolis Monte Carlo type algorithm and modifications that incorporate replica exchange is demonstrated. A comparison is provided with pseudo-random sampling of polymorphs for the molecule coumarin. The choice to test a design of this algorithm as relevant for enhanced sampling of crystal structures was due to the obvious relation between molecular structure variables and corresponding crystal polymorphs as representative of the inherent vapor to crystal transitions that exist in nature. Additionally, it is shown that the trajectories of extended variables can be harnessed to extract fluctuation properties that can lead to valuable insights. A novel thermodynamic variable is introduced: the free energy difference between ensembles of Z' = 1 and Z' = 2 crystal polymorphs.

An innovative dual-thickness semi-transparent beamstop designed to enhance the performance of small-angle X-ray scattering (SAXS) experiments is introduced. This design integrates two absorbers of differing thicknesses side by side into a single attenuator, known as a beamstop. Instead of completely stopping the direct beam, it attenuates it, allowing the SAXS detector to measure the transmitted beam through the sample. This approach achieves true synchronization in measuring both scattered and transmitted signals and effectively eliminates higher-order harmonic contributions when determining the transmission light intensity through the sample. This facilitates and optimizes signal detection and background subtraction. This contribution details the theoretical basis and practical implementation of this solution at the SAXS station on the 1W2A beamline at the Beijing Synchrotron Radiation Facility. It also anticipates its application at other SAXS stations, including that at the forthcoming High Energy Photon Source, providing an effective solution for high-precision SAXS experiments.

In the title compound, [Ni(C13H13N4S)2]·0.33CH3OH·0.67H2O, the NiII atom is coordinated by two tridentate quinoline-2-carboxaldehyde 4-ethyl­thio­semi­car­ba­zonate ligands in a distorted octa­hedral shape. At 100 K, the crystal symmetry is monoclinic (space group P21/n). A mixture of water and methanol crystallizes with the title complex, and one of the ethyl groups in the coordinating ligands is disordered over two positions, with an occupancy ratio of 58:42. There is inter­molecular hydrogen bonding between the solvent mol­ecules and the amine and thiol­ate groups in the ligands. No other significant inter­actions are present in the crystal packing.

Complex I (proton-pumping NADH:ubiquinone oxidoreductase) is the first component of the mitochondrial respiratory chain. In recent years, high-resolution cryo-EM studies of complex I from various species have greatly enhanced the understanding of the structure and function of this important membrane-protein complex. Less well studied is the structural basis of complex I biogenesis. The assembly of this complex of more than 40 subunits, encoded by nuclear or mitochondrial DNA, is an intricate process that requires at least 20 different assembly factors in humans. These are proteins that are transiently associated with building blocks of the complex and are involved in the assembly process, but are not part of mature complex I. Although the assembly pathways have been studied extensively, there is limited information on the structure and molecular function of the assembly factors. Here, the insights that have been gained into the assembly process using cryo-EM are reviewed.

Eukaryotic TIR (Toll/interleukin-1 receptor protein) domains signal via TIR–TIR interactions, either by self-association or by interaction with other TIR domains. In mammals, TIR domains are found in Toll-like receptors (TLRs) and cytoplasmic adaptor proteins involved in pro-inflammatory signaling. Previous work revealed that the MAL TIR domain (MALTIR) nucleates the assembly of MyD88TIR into crystalline arrays in vitro. A microcrystal electron diffraction (MicroED) structure of the MyD88TIR assembly has previously been solved, revealing a two-stranded higher-order assembly of TIR domains. In this work, it is demonstrated that the TIR domain of TLR2, which is reported to signal as a heterodimer with either TLR1 or TLR6, induces the formation of crystalline higher-order assemblies of MyD88TIR in vitro, whereas TLR1TIR and TLR6TIR do not. Using an improved data-collection protocol, the MicroED structure of TLR2TIR-induced MyD88TIR microcrystals was determined at a higher resolution (2.85 Å) and with higher completeness (89%) compared with the previous structure of the MALTIR-induced MyD88TIR assembly. Both assemblies exhibit conformational differences in several areas that are important for signaling (for example the BB loop and CD loop) compared with their monomeric structures. These data suggest that TLR2TIR and MALTIR interact with MyD88 in an analogous manner during signaling, nucleating MyD88TIR assemblies uni­directionally.

During the automatic processing of crystallographic diffraction experiments, beamstop shadows are often unaccounted for or only partially masked. As a result of this, outlier reflection intensities are integrated, which is a known issue. Traditional statistical diagnostics have only limited effectiveness in identifying these outliers, here termed Not-Excluded-unMasked-Outliers (NEMOs). The diagnostic tool AUSPEX allows visual inspection of NEMOs, where they form a typical pattern: clusters at the low-resolution end of the AUSPEX plots of intensities or amplitudes versus resolution. To automate NEMO detection, a new algorithm was developed by combining data statistics with a density-based clustering method. This approach demonstrates a promising performance in detecting NEMOs in merged data sets without disrupting existing data-reduction pipelines. Re-refinement results indicate that excluding the identified NEMOs can effectively enhance the quality of subsequent structure-determination steps. This method offers a prospective automated means to assess the efficacy of a beamstop mask, as well as highlighting the potential of modern pattern-recognition techniques for automating outlier exclusion during data processing, facilitating future adaptation to evolving experimental strategies.

The orientation ordering and assembly behavior of silica–nickel Janus particles in a static external magnetic field were probed by ultra small-angle X-ray scattering (USAXS). Even in a weak applied field, the net magnetic moments of the individual particles aligned in the direction of the field, as indicated by the anisotropy in the recorded USAXS patterns. X-ray photon correlation spectroscopy (XPCS) measurements on these suspensions revealed that the corresponding particle dynamics are primarily Brownian diffusion [Zinn, Sharpnack & Narayanan (2023). Soft Matter, 19, 2311–2318]. At higher fields, the magnetic forces led to chain-like configurations of particles, as indicated by an additional feature in the USAXS pattern. A theoretical framework is provided for the quantitative interpretation of the observed anisotropic scattering diagrams and the corresponding degree of orientation. No anisotropy was detected when the magnetic field was applied along the beam direction, which is also replicated by the model. The method presented here could be useful for the interpretation of oriented scattering patterns from a wide variety of particulate systems. The combination of USAXS and XPCS is a powerful approach for investigating asymmetric colloidal particles in external fields.

In the folded state, biomolecules exchange between multiple conformational states crucial for their function. However, most structural models derived from experiments and computational predictions only encode a single state. To represent biomolecules accurately, we must move towards modeling and predicting structural ensembles. Information about structural ensembles exists within experimental data from X-ray crystallography and cryo-electron microscopy. Although new tools are available to detect conformational and compositional heterogeneity within these ensembles, the legacy PDB data structure does not robustly encapsulate this complexity. We propose modifications to the macromolecular crystallographic information file (mmCIF) to improve the representation and interrelation of conformational and compositional heterogeneity. These modifications will enable the capture of macromolecular ensembles in a human and machine-interpretable way, potentially catalyzing breakthroughs for ensemble–function predictions, analogous to the achievements of AlphaFold with single-structure prediction.

X-ray scattering has become a major tool in the structural characterization of nanoscale materials. Thanks to the widely available experimental and computational atomic models, coordinate-based X-ray scattering simulation has played a crucial role in data interpretation in the past two decades. However, simulation of real-space pair distance distribution functions (PDDFs) from small- and wide-angle X-ray scattering, SAXS/WAXS, has been relatively less exploited. This study presents a comparison of PDDF simulation methods, which are applied to molecular structures that range in size from β-cyclo­dextrin [1 kDa molecular weight (MW), 66 non-hydrogen atoms] to the satellite tobacco mosaic virus capsid (1.1 MDa MW, 81 960 non-hydrogen atoms). The results demonstrate the power of interpretation of experimental SAXS/WAXS from the real-space view, particularly by providing a more intuitive method for understanding of partial structure contributions. Furthermore, the computational efficiency of PDDF simulation algorithms makes them attractive as approaches for the analysis of large nanoscale materials and biological assemblies. The simulation methods demonstrated in this article have been implemented in stand-alone software, SolX 3.0, which is available to download from https://12idb.xray.aps.anl.gov/solx.html.

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How do galaxies such as our Milky Way come into existence? How do they grow and change over time? The science behind galaxy formation has long been a puzzle, but a University of Arizona-led team of scientists is one step closer to finding answers, thanks to supercomputer simulations. Observing real galaxies in space can only provide snapshots in time, so researchers who study how galaxies evolve over billions of years need to use computer simulations. Traditionally, astronomers have used simulations to invent theories of galaxy formation and test them, but they have had to proceed one galaxy at a time. Peter Behroozi of the university's Steward Observatory and colleagues overcame this hurdle by generating millions of different universes on a supercomputer, each according to different physical theories for how galaxies form. The findings challenge fundamental ideas about the role dark matter plays in galaxy formation, the evolution of galaxies over time and the birth of stars. The study is the first to create self-consistent universes that are exact replicas of the real ones -- computer simulations that each represent a sizeable chunk of the actual cosmos, containing 12 million galaxies and spanning the time from 400 million years after the Big Bang to the present day. The results from the "UniverseMachine," as the authors call their approach, have helped resolve the long-standing paradox of why galaxies cease to form new stars even when they retain plenty of hydrogen gas, the raw material from which stars are forged. The research is partially funded by NSF's Division of Physics through grants to UC Santa Barbara's Kavli Institute for Theoretical Physics and the Aspen Center for Physics.

Image credit: NASA/ESA/J. Lotz and the HFF Team/STScI

As immigrants and their descendants become integrated into U.S. society, many aspects of their lives improve, including measurable outcomes such as educational attainment, occupational distribution, income, and language ability, but their well-being declines in the areas of health, crime, and family patterns, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Two new rapid expert consultations from the National Academies of Sciences, Engineering, and Medicine offer lessons learned from the 2020 fall semester regarding COVID-19 testing and guidance on student behavior, as college administrators plan for the 2021 spring semester.

Decision-makers leading COVID-19 vaccine rollouts need to begin communicating with the public immediately if they have not already — emphasizing public support for vaccinations, leveraging celebrity and community champion endorsements, and focusing on those who are skeptical or hesitant of the vaccines rather than firmly opposed — to ensure demand and promote uptake, says a new rapid expert consultation from the National Academies of Sciences, Engineering, and Medicine.

Scientists at Iowa State University have developed a new formulation that helps to explain the self-assembly of atoms into nanoclusters and to advance the scientific understanding of related nanotechnologies. Their research offers a theoretical framework to explain the relationship between the distribution of "capture zones," the regions that surround the nanoscale "islands" formed by deposition on surfaces, and the underlying nucleation or formation process.

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Krishnan will be overseeing the rollout of the recently enacted Digital Personal Data Protection (DPDP) Act, 2023, which is the outcome of almost five years of five years of drafts and consultations. From a digital economy perspective, there are some good features in the DPDP act but it also has some gaps which have been identified by several legal experts.

When it comes to water, some materials have a split personality - and some of these materials could hold the key to new ways of harnessing solar energy.

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Semiconductor design global capability centres (GCC) account for approximately 4 per cent of India's total GCCs, with a growth rate of about 7 per cent in the last two decades.

Grey has created a strict file workflow, Myke had to cross his fingers, and they both divulge their Screen Crimes.

The supplier intends to help producers eliminate artificial preservatives with naturally derived options.

The design is intended to offer bakery customers faster installation.

Point Five Packaging, a supplier of modified atmosphere packaging (MAP) equipment and packaging solutions for various food industry sectors, has introduced the P5-RM Semi-Automatic Seal System.