"The Commission is of the view that evidence provided by JSW Paints is prima-facie sufficient to indicate that Asian Paints has denied access to the distribution channels in the relevant market to JSW Paints by threatening and coercing such dealers through various means," the fair trade regulator said.

The Ikea compliance team last week visited Vadodara-based Shaily Engineering, the company that had supplied the mugs, as part of the investigation, a source said. Ikea was prompted to recall the mugs after tests found excessive level of dibutyl phthalate (DBP), a substance that is used as plasticisers.

Attorneys for Rick Bright, the government scientist who said he had been reassigned and subsequently filed a whistleblower complaint , say a government watchdog agrees that he should be reinstated to his post. Bright was serving as director of the Biomedical Advanced Research and Development Authority, which is working on a vaccine to combat the coronavirus. He said he was ousted from the position last month because he wanted to spend money on safe and vetted treatments for COVID-19 — not on ones without "scientific merit," such as hydroxychloroquine, the anti-malarial drug that President Trump and others had been touting. Trump on Wednesday called Bright "a disgruntled employee who's trying to help the Democrats win an election." Bright's attorneys say that the Office of Special Counsel, which hears whistleblower cases, determined there were "reasonable grounds" to believe that his removal was retaliatory and therefore prohibited. Bright's attorneys say OSC plans to contact the

ROME, April 26 -- Prime Minister Silvio Berlusconi fended off opposition attacks Tuesday over reports that the U.S. military had absolved its soldiers of any blame in killing an Italian intelligence agent who had just rescued a hostage in Iraq.

ROME, April 27 -- Dissatisfied with the results of a joint investigation with the United States, Italy on Wednesday began its own probe into the March 4 killing of one of its intelligence agents by U.S. troops in Baghdad.

The 317-page report by the inspector general also found that giving the contract to a single company — Microsoft — rather than dividing it among competitors was "consistent with applicable acquisition standards."

WASHINGTON (AP) — House lawmakers investigating the market dominance of Big Tech are asking Amazon CEO Jeff Bezos to testify to address possible misleading statements by the company on its competition practices. In a letter to Bezos on Friday, leaders of the House Judiciary Committee from both parties are holding out the threat of a […]

A federal investigation into where the U.S. failed to prepare for the current pandemic is a good idea.

A team of WA Police officers will be deployed to Japan as part of a revived investigation into former trade commissioner Craig Peacock, accused of misusing his position to pocket $540,000 in taxpayer funds.

A senior Corrections executive and a plasterer appear in court following an ICAC investigation, with the pair accused of corruption offences relating to a planned $150 million upgrade of South Australia's biggest prison.

A local politician's stab at finding romance on reality television could backfire, as the Noosa Mayor considers a code of conduct probe into Councillor Jess Glasgow.

The Fair Work Ombudsman will be auditing retailers across Perth and regional Western Australia, in response to a spike in complaints.

Police are investigating a spate of bushfires in Albany over the weekend, which it is suspected may have been deliberately lit.

Investigations are continuing into the cause of a blaze in the Western Australian Wheatbelt town of Corrigin.

MORNING BRIEFING: An aged care operator at the centre of Australia's second biggest coronavirus cluster has requested a worker be stood down after alleged breaches of infection control.

Health authorities in NSW investigate the source of five mystery coronavirus infections discovered yesterday, as the total number of cases rises by nine to 3,042.

A new coronavirus case diagnosed overnight takes Tasmania's tally to 72, as authorities release a list of destinations visited by two interstate travellers who later tested positive for COVID-19.

An investigation into a coronavirus cluster in north-west Tasmania finds some staff worked in local hospitals for several days while experiencing symptoms, but the Premier stresses no-one is to blame.

News Corp Australia claimed CSIRO's Australian Centre for Disease Preparedness in Geelong Victoria has been collaborating with the Wuhan Institute of Virology.

The family of a man who went missing in Victoria's Latrobe Valley last month say they "fear the worst" and are urging anyone who has seen him to contact police.

Two more Victorian police officers are suspended over the leak of unauthorised photos of former AFL coach and player Dean Laidley in a police station, as the state's corruption watchdog says it will oversee the investigation into the leak.

The Liberals' plan to open up World Heritage Area and national parks to more tourism developments has been contentious from day one now, it has attracted the attention of Tasmania's auditor-general.

Almost six years after her father died in a mining accident on Tasmania's west coast, Tameka Sylvester is still waiting for answers with the family learning of inquest news via social media.

A mansion in Melbourne's east, newly constructed units and more than 3,000 acres of Tasmanian farmland are among the assets seized by Australian Federal Police as part of a two-year investigation into alleged money laundering by Chinese nationals.

GRAPHIC WARNING: The Department of Agriculture is investigating the alleged inhumane killing of Australian cattle at the Festival of Sacrifice in Indonesia.

A Federal Court judge finds the Registered Organisations Commission's investigation into donations made to the activist group in 2006 when former opposition leader Bill Shorten was leading the union was not politically motivated, but it was launched on a "flawed"basis.

A day after the discovery of a body, confirmed as Comancheros bikie Shane Ross, police divers search for a gun and declare a double homicide investigation linked to another man's death on Friday night.

RT @mrbromwich: I have been in and around DOJ since 1983. I have never seen a case dropped after someone has pled guilty and the underlying facts demonstrate beyond any shadow of a doubt he is guilty. This is simply a pardon by another name. A black day in DOJ history.

Outrage is spreading over a shooting of a black man that led to murder charges more than two months later against a white father and son, but "all that matters is what the facts tell us,” Georgia Bureau of Investigation Director Vic Reynolds said Friday.

The message came after her comments on reopening businesses

'B' is for basic controls that up and disappeared

A study of the UK online advertising market, conducted by global accounting firm PwC, has found that publishers get just half of what advertisers spend, with the other half siphoned off by ad-supply chain intermediaries.…

Hayabusa 2 expected to return with out-of-this-world material in December

Video Close-up footage of asteroid Ryugu, taken by the Hayabusa 2 spacecraft as it touched down to retrieve a sample, reveals the near-Earth object’s surface may have been torched by the Sun as its orbit changed over time.…

Opposition spokesman on tourism, Dr Wykeham McNeill, is calling for an investigation into allegations that some employers of tourism workers have not been turning over income tax deductions to government.  The situation has resulted in...

IBM (NYSE: IBM) announced today that the Victoria University of Wellington, on behalf of the Murchison Widefield Array (MWA) Consortium, has selected IBM systems technology to help scientists probe the origins of the universe.

New York Attorney General Letitia James is investigating allegations of racially discriminatory tactics by Long Island real estate agents as described in a sweeping Newsday report.

Shirr Teved was inside her home near Foster Ave. in Flatbush when a fire broke out about 10:30 p.m. Monday.

Marty Blazer, an informant in the federal investigation into college basketball corruption that ensnared USC, is assisting the NCAA in its probe.

Tesla limited the range for Model S and Model X charging after fires. The National Highway Traffic Safety Administration wants to know why.

The Defense Department's Inspector General has opened an investigation into whether U.S. troops were discouraged from reporting the rape and sexual abuse of children by their Afghan allies.

Police in Haiti are investigating allegations that the president of the national football federation raped teenage girls.

The following article, ‘Schiff in Panic Mode’: Sources Say Russia Probe Transcripts Affirm Officials Found Nothing on Collusion, was first published on 100PercentFedUp.com.

Transcripts of House Intelligence Committee interviews have been cleared for release, and Adam Schiff is reportedly in panic mode. Unfortunately for Schiff, top law enforcement and intel officials said they saw no evidence of collusion between the Trump campaign and Russia in the transcripts. Republicans sought and got approval for the release of the transcripts […]

Continue reading: ‘Schiff in Panic Mode’: Sources Say Russia Probe Transcripts Affirm Officials Found Nothing on Collusion ...

Ileana M. Cristea
Dec 1, 2005; 4:1933-1941
Research

Reactive oxygen and nitrogen species have been implicated in many biological processes and diseases, including immune responses, cardiovascular dysfunction, neurodegeneration, and cancer. These chemical species are short-lived in biological settings, and detecting them in these conditions and diseases requires the use of molecular probes that form stable, easily detectable, products. The chemical mechanisms and limitations of many of the currently used probes are not well-understood, hampering their effective applications. Boronates have emerged as a class of probes for the detection of nucleophilic two-electron oxidants. Here, we report the results of an oxygen-18–labeling MS study to identify the origin of oxygen atoms in the oxidation products of phenylboronate targeted to mitochondria. We demonstrate that boronate oxidation by hydrogen peroxide, peroxymonocarbonate, hypochlorite, or peroxynitrite involves the incorporation of oxygen atoms from these oxidants. We therefore conclude that boronates can be used as probes to track isotopically labeled oxidants. This suggests that the detection of specific products formed from these redox probes could enable precise identification of oxidants formed in biological systems. We discuss the implications of these results for understanding the mechanism of conversion of the boronate-based redox probes to oxidant-specific products.

The Government has mechanisms to investigate complaints against civil servants impartially, Secretary for the Civil Service Patrick Nip said today.

Mr Nip made the remarks in response to media queries on recent allegations levelled against senior police officers.

He said: “There are established mechanisms to investigate every complaint in accordance with the procedures and rules. Depending on the circumstances and the case details, some are being handled by departments and bureaus. Some may be handled by the Civil Service Bureau.

“There are established mechanisms in dealing with that. Of course we would handle each and every complaint in a very serious and impartial manner.”

(To watch the full press briefing with sign language interpretation, click here.)

Chief Executive Carrie Lam today said law enforcement agencies are investigating cases where police officers are suspected of breaching property rules and will give a full account to society.

Speaking to reporters before the Executive Council meeting this morning, Mrs Lam said nobody is above the law.

“The law will be applied in the same manner regardless of the status, the background, the political affiliation of that particular person.

“As far as I am concerned, as the Chief Executive of Hong Kong and also as an individual, no law-breaking behaviour is acceptable. But it is not for me to stand here to judge each and every case because every case or every complaint has to be investigated and analysed by the law enforcement agencies.

“I am sure that they will do it as diligently as possible and will give a full account to society, especially given the recent concerns.”

Purpose: This prospective study evaluated the imaging performance of a novel immunological pretargeting positron-emission tomorgraphy (immuno-PET) method in patients with HER2-negative, carcinoembryonic antigen (CEA)-positive, metastatic breast cancer (BC), compared to computed tomography (CT), bone magnetic resonance imaging (MRI), and ¹⁸Fluorodeoxyglucose PET (FDG-PET). Patients and Methods: Twenty-three patients underwent whole-body immuno-PET after injection of 150 MBq ⁶⁸Ga-IMP288, a histamine-succinyl-glycine peptide given following initial targeting of a trivalent anti-CEA, bispecific, anti-peptide antibody. The gold standards were histology and imaging follow-up. Tumor standard uptake values (SUV_max and SUVmean) were measured, and tumor burden analyzed using Total Tumor Volume (TTV) and Total Lesion Activity (TLA). Results: Total lesion sensitivity of immuno-PET and FDG-PET was 94.7% (1116/1178) and 89.6% (1056/1178), respectively. Immuno-PET had a somewhat higher sensitivity than CT and FDG-PET in lymph nodes (92.4% vs 69.7% and 89.4%, respectively) and liver metastases (97.3% vs 92.1% and 94.8%, respectively), whereas sensitivity was lower for lung metastases (48.3% vs 100% and 75.9%, respectively). Immuno-PET showed higher sensitivity than MRI and FDG-PET for bone lesions (95.8% vs 90.7% and 89.3%, respectively). In contrast to FDG-PET, immuno-PET disclosed brain metastases. Despite equivalent tumor SUV_max, SUVmean, and TTV, TLA was significantly higher with immuno-PET compared to FDG PET (P = 0.009). Conclusion: Immuno-PET using anti-CEA/anti-IMP288 bispecific antibody, followed by ⁶⁸Ga-IMP288, is a potentially sensitive theranostic imaging method for HER2-negative, CEA-positive, metastatic BC patients, and warrants further research.

The Trump administration failed to conduct effective screening of passengers from South Korea and Italy for the coronavirus when those countries were experiencing rapid expansion in COVID-19 cases.

The Supreme Court on Friday granted a Justice Department request to temporarily block release of secret grand jury material from special counsel Robert Mueller's probe to Congress.

The Florida supreme court has ordered a statewide grand jury with a broad mandate to investigate school safety.