motor to wire multiple horsepower motor By english.al-akhbar.com Published On :: to wire multiple horsepower motor Full Article
motor to wire a motorcycle headlight By english.al-akhbar.com Published On :: to wire a motorcycle headlight Full Article
motor Climate-Resilient Connectivity for the Eastern Economic Corridor Project: The Intercity Motorway No. 7 (Extension to Link with U-Tapao International Airport) By www.adb.org Published On :: 2024-11-06 The U-Tapao International Airport is the core infrastructure of the EEC and its expansion project is to be implemented via Public-Private Partnership modality. Land transport network connecting the U-Tapao International Airport in the Eastern Economic Corridor (EEC) to the rest of the Pattaya City and country cannot adapt to changing needs as a result of the expansion plan of the airport due to the limitations of the existing land transport network to cope with traffic increase. Full Article
motor Paramotorists collect rare plant species from Peruvian desert oases By www.newscientist.com Published On :: Wed, 09 Oct 2024 09:00:47 +0100 Kew scientists use paramotorists to collect rare plant species from Peruvian desert oases Full Article
motor Motor made from bacteria parts is one of the smallest ever built By www.newscientist.com Published On :: Thu, 17 Oct 2024 13:00:11 +0100 The natural motors that power tail-like appendages in bacteria seem to have a single evolutionary origin, allowing parts from different species to be combined to create a tiny new engine Full Article
motor Sensory-Motor Neuropathy in Mfn2 T105M Knock-in Mice and Its Reversal by a Novel Piperine-Derived Mitofusin Activator [Neuropharmacology] By jpet.aspetjournals.org Published On :: 2024-10-18T07:04:15-07:00 Mitochondrial dysfunction is a hallmark of many genetic neurodegenerative diseases, but therapeutic options to reverse mitochondrial dysfunction are limited. While recent studies support the possibility of improving mitochondrial fusion/fission dynamics and motility to correct mitochondrial dysfunction and resulting neurodegeneration in Charcot-Marie-Tooth disease (CMT) and other neuropathies, the clinical utility of reported compounds and relevance of preclinical models are uncertain. Here, we describe motor and sensory neuron dysfunction characteristic of clinical CMT type 2 A in a CRISPR/Casp-engineered Mfn2 Thr105Met (T105M) mutant knock-in mouse. We further demonstrate that daily oral treatment with a novel mitofusin activator derived from the natural product piperine can reverse these neurologic phenotypes. Piperine derivative 8015 promoted mitochondrial fusion and motility in Mfn2-deficient cells in a mitofusin-dependent manner and reversed mitochondrial dysfunction in cultured fibroblasts and reprogrammed motor neurons from a human CMT2A patient carrying the MFN2 T105M mutation. Like previous mitofusin activators, 8015 exhibited stereospecific functionality, but the more active stereoisomer, 8015-P2, is unique in that it has subnanomolar potency and undergoes entero-hepatic recirculation which extends its in vivo half-life. Daily administration of 8015-P2 to Mfn2 T105M knock-in mice for 6 weeks normalized neuromuscular and sensory dysfunction and corrected histological/ultrastructural neurodegeneration and neurogenic myoatrophy. These studies describe a more clinically relevant mouse model of CMT2A and an improved mitofusin activator derived from piperine. We posit that 8015-P2 and other piperine derivatives may benefit CMT2A or other neurodegenerative conditions wherein mitochondrial dysdynamism plays a contributory role. SIGNIFICANCE STATEMENT Mitochondrial dysfunction is widespread and broadly contributory in neurodegeneration, but difficult to target therapeutically. Here, we describe 8015-P2, a new small molecule mitofusin activator with ~10-fold greater potency and improved in vivo pharmacokinetics versus comparators, and demonstrate its rapid reversal of sensory and motor neuron dysfunction in an Mfn2 T105M knock-in mouse model of Charcot-Marie-Tooth disease type 2 A. These findings further support the therapeutic approach of targeting mitochondrial dysdynamism in neurodegeneration. Full Article
motor Motorists urged to plan ahead with Kincardine Bridge due to close By www.heraldscotland.com Published On :: Tue, 12 Nov 2024 11:00:12 +0000 Motorists have been urged to plan ahead with a major bridge due to close for work is carried out. Full Article
motor Exclusive: Dinosaur Polo Club Interview – CEO Amie Wolken on Mini Metro, Mini Motorways, the Team, Free DLC, Working With Apple, Ports, and More By toucharcade.com Published On :: Tue, 20 Aug 2024 17:17:47 +0000 When thinking about the classics or games I’d recommend people play on mobile, Mini Metro is one of the best … Continue reading "Exclusive: Dinosaur Polo Club Interview – CEO Amie Wolken on Mini Metro, Mini Motorways, the Team, Free DLC, Working With Apple, Ports, and More" Full Article Android Apple Arcade Featured Games Interview Interviews iPad Games iPhone games News Universal
motor F1: Mercedes motorisera Alpine à partir de 2026 By www.journaldemontreal.com Published On :: Tue, 12 Nov 2024 09:19:36 EST C'était une nouvelle attendue. Full Article
motor Motorists who bought cars on finance could share in billions By www.bbc.com Published On :: Tue, 12 Nov 2024 09:27:29 GMT The car finance industry is setting aside billions to pay for potential claims after a test case. Full Article
motor A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech By www.medgadget.com Published On :: Tue, 07 Nov 2023 20:46:05 +0000 Charco Neurotech, a medtech company based in the United Kingdom, has developed CUE1, a non-invasive wearable that is intended to assist those with Parkinson’s disease to manage their motor symptoms. The device is typically affixed to the sternum, and provides vibratory action in a focused region of the body. The technology is based on the […] Full Article Exclusive Neurology Rehab CharcoLtd parkinson's
motor Discovery en Español aumenta la velocidad de sus 'Lunes De Motores' con transformaciones extremas de camiones - Texas Trocas Promo Clip By www.multivu.com Published On :: 02 Sep 2014 17:00:00 EDT Conoce a la familia Méndez, pionera en la transformación extrema de camiones. Texas Trocas, nueva serie de Discovery en Español. Estreno 15 de septiembre a las 10PM E/P. Full Article Entretenimiento Televisión Aviso de Contenido para Radio TV Noticias para la comunidad hispana Nuevos productos servicios Florida
motor Assessee can avail ITC only on tax paid on services for leasing/ renting/ hiring of motor vehicles for women's safety By www.caclubindia.com Published On :: Wed, 23 Oct 2024 14:30:30 GMT The AAR, Tamil Nadu in the case of M/s. CMA CGM Global Business Services (India) (P.) Ltd., In Re [Order No. 15/ARA/2024 dated July 15, 2024] ruled that an Assessee is eligible to avail input services in respect of leasing/ renting/ hiring of motor vehicles of motor vehicles to provide transportatio Full Article
motor Go Motorsport By www.gomotorsport.net Published On :: Wed, 11 Mar 2009 09:14:36 GMT Full Article Motorsport
motor Bentley Motors amână planul pentru producția de vehicule electrice By www.forbes.ro Published On :: Tue, 12 Nov 2024 11:07:29 +0000 Bentley Motors Ltd. amână planul de a oferi doar vehicule complet electrice (EV – electric vehicles) până în 2030, pentru că vânzările de EV-uri continuă să dezamăgească la nivel de industrie. Compania va extinde termenul pentru strategia de afaceri „Beyond100” – acum denumită „Beyond100+” – cu cinci ani, până în 2035, a declarat președintele și ... The post Bentley Motors amână planul pentru producția de vehicule electrice appeared first on Forbes Romania. Full Article Actualitate Afaceri Auto Bani și Investiţii
motor 4000 ಕುಸಿತ! 50MP ಸೆಲ್ಫಿ ಕ್ಯಾಮೆರಾ.. 125W ಚಾರ್ಜಿಂಗ್.. ಕಡಿಮೆ ಬೆಲೆಗೆ Motorola 5G ಫೋನ್ ಸೇಲ್ By kannada.gizbot.com Published On :: Mon, 11 Nov 2024 20:56:32 +0530 ಮೊಟೊರೊಲಾ ಕಂಪನಿಯ ಮೊಬೈಲ್ಗಳಿಗೆ ಮಾರುಕಟ್ಟೆಯಲ್ಲಿ ಭಾರೀ ಬೇಡಿಕೆಯಿದೆ. ಸ್ಮಾರ್ಟ್ಫೋನ್ ಪ್ರಿಯರು ಸಹ ಈ ಫೋನ್ಗಳನ್ನು ಇಷ್ಟಪಟ್ಟು ಖರೀದಿಸುತ್ತಾರೆ. ಅದರಂತೆ, ಕಂಪನಿಯು ಆಗಾಗ್ಗೆ ತನ್ನ ಅಭಿಮಾನಿಗಳಿಗೆ ಬೊಂಬಾಟ್ ಆಫರ್ಗಳನ್ನು ನೀಡುತ್ತದೆ. ಇದೀಗ, ಮೊಟೊರೊಲಾ ಎಡ್ಜ್ 50 ಪ್ರೊ 5G (Motorola Edge 50 Pro 5G) ಫೋನಿನ ಬೆಲೆ ಇಳಿಕೆ ಮಾಡಿದೆ. ನೀವು, 4 ಸಾವಿರ ರೂ. ರಿಯಾಯಿತಿಯೊಂದಿಗೆ Full Article
motor Hyundai Motor India Q2 Results: लिस्टिंग के बाद पहली बार आए रिजल्ट्स! मुनाफा घटा, शेयर भी 2% टूटा By hindi.goodreturns.in Published On :: Tue, 12 Nov 2024 14:27:19 +0530 Hyundai Motor India Q2 Results: शेयर बाजार में लिस्टेड कंपनियां तिमाही नतीजे जारी कर रही. इस कड़ी में ऑटो सेक्टर की कंपनी हुंडई मोटर इंडिया ने भी सितंबर तिमाही के नतीजे जारी कर दिए हैं. हाल ही में लिस्ट शेयर नतीजों Full Article
motor BMW Motorrad Unveils Concept F 450 GS Adventure Motorcycle: All Details Here By www.drivespark.com Published On :: Fri, 08 Nov 2024 10:53:33 +0530 BMW Motorrad has unveiled the Concept F 450 GS, a new addition to its motorcycle lineup. This concept bike is built on a fresh 450cc platform and features a twin-cylinder engine producing 48 bhp. The design draws inspiration from BMW's larger Full Article
motor Rolex Monterey Motorsports Reunion 2025 To Feature Historic Race Groups And Formula One Exhibition By www.drivespark.com Published On :: Wed, 13 Nov 2024 03:51:05 +0530 Discover the exciting race groups and exhibitions at the Rolex Monterey Motorsports Reunion 2025, celebrating Formula One's 75th Anniversary. Full Article
motor Hyundai Motor America Secures 2024 Great Place To Work Certification For Employee Satisfaction By www.drivespark.com Published On :: Wed, 13 Nov 2024 04:03:08 +0530 Hyundai Motor America earns the Great Place To Work certification for the second consecutive year, reflecting employee satisfaction and workplace culture. Full Article
motor Motorsport FMSCI | Triple delight for Jaden and Abhay By www.thehindu.com Published On :: Sun, 25 Feb 2024 18:28:59 +0530 Full Article Motorsport
motor MOTORSPORTS | Aditya, Virender seize overall lead in MMSC South India Rally By www.thehindu.com Published On :: Sat, 16 Mar 2024 21:16:40 +0530 Full Article Motorsport
motor Motor racing | Verstappen wants more focus on car, not Red Bull drama By www.thehindu.com Published On :: Fri, 22 Mar 2024 04:01:00 +0530 Verstappen, who has won the last three world championships with Red Bull, said the internal strife had no impact on his performance or comfort within the team. Full Article Motorsport
motor MOTORSPORTS | Young Indian racers excited for Formula 4 Indian championship By www.thehindu.com Published On :: Tue, 20 Aug 2024 19:30:37 +0530 Full Article Motorsport
motor Chennai’s night street race a shot in the arm for Indian motorsports By www.thehindu.com Published On :: Sat, 31 Aug 2024 07:25:47 +0530 The initiative reflects Tamil Nadu’s commitment to cultivate a vibrant racing culture and inspire the NextGen racing drivers, engineers and race mechanics Full Article Motorsport
motor A humdinger looms in the three-day Indian National Motorcycle Racing Championship By www.thehindu.com Published On :: Thu, 05 Sep 2024 20:08:39 +0530 The contenders across all categories are closely bunched as the fourth round of the INMRC gets under way on September 6 Full Article Motorsport
motor Indian National Motorcycle Racing Championship | Chiranth Vishwanath secures two pole positions By www.thehindu.com Published On :: Fri, 06 Sep 2024 19:12:30 +0530 Full Article Motorsport
motor A unique approach to nurturing Indian motorsport engineers — the L.I.M.E. way By www.thehindu.com Published On :: Tue, 17 Sep 2024 06:19:00 +0530 United Motorsports Academy — founded by former Red Bull engineer Sangodkar, and Rane — provides a two-week course to qualify for an internship in the IRL and F4 series as part of a scholarship called Launchpad for Indian Motorsports Engineers; students learn about the basics and intricacies of the sport which gives them an opening into the world of fast-paced action Full Article Motorsport
motor National Motorcycle Racing Championship set for grand climax at MIC By www.thehindu.com Published On :: Thu, 03 Oct 2024 15:14:10 +0530 Over 100 entrants, representing 19 teams, will vie for top honours across 19 races at MRF MMSC FMSCI Indian National Motorcycle Racing Championship in Chennai on October 4 Full Article Motorsport
motor Everything you need to know about India’s first high-voltage e-motorcycle Raptee.HV T30 By www.thehindu.com Published On :: Mon, 21 Oct 2024 15:30:52 +0530 This Chennai-based startup has introduced the country’s first high-voltage electric two-wheeler, a machine that merges electric car technology with motorcycle performance Full Article Motoring
motor Honda Motorcycle and Scooter India unveils India’s first 300cc flex-fuel bike By www.thehindu.com Published On :: Tue, 29 Oct 2024 15:45:29 +0530 Honda Motorcycle &and Scooter India has launched the new CB300F Flex-Fuel, marking a notable step towards environmentally friendly mobility solutions in India. The motorcycle is India’s first 300cc flex-fuel vehicle and aligns with the country’s broader goals of promoting greener technologies. Full Article Motoring
motor A motor that cuts import of Chinese raw material By www.thehindubusinessline.com Published On :: Sun, 25 Aug 2024 20:52:00 +0530 Chennai startup Viridian Ingni Propulsion develops low-cost motor that works with magnets free of rare earth materials Full Article Emerging Entrepreneurs
motor These motorcyclists at the India Bike Week shatter myths about ‘women bikers’ By www.thehindu.com Published On :: Mon, 28 Nov 2022 16:10:28 +0530 Maral Yazarloo-Pattrick, Sameera Dahiya, and Urvashi Patole smash stereotypes about female bikers in India Full Article Motoring
motor Tamil Nadu aims to position Chennai as the heart of motorsport, chess, and sailing By www.thehindubusinessline.com Published On :: Fri, 30 Aug 2024 20:08:04 +0530 State allocates ₹30 crore to support the IRF 2024 event, with an additional ₹12 crore dedicated to publiciszing it Full Article Variety
motor Bajaj Auto motorcycle sales marginally up in August By www.thehindu.com Published On :: Tue, 02 Sep 2014 11:42:09 +0530 Full Article Industry
motor Tata Motors to acquire Ford India's Sanand plant to expand production capacity By www.thehindu.com Published On :: Mon, 08 Aug 2022 11:08:41 +0530 Tata Motors said with its manufacturing capacity nearing saturation, the acquisition is timely and a win-win for all stakeholders Full Article Companies
motor Vauxhall Motors Ltd. MarketLine Company Profile [electronic journal]. By encore.st-andrews.ac.uk Published On :: Marketline Full Article
motor Frequent traffic snarls pose hardship to motorists in Tiruchi By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:45:36 +0530 It is common to see vehicles lining up for a long distance from the traffic signal near Cauvery bridge to Anna Statue. Full Article Tiruchirapalli
motor Tata Motors signs MoU with ASDC for skill development By www.thehindu.com Published On :: Wed, 01 Jun 2016 00:00:00 +0530 Full Article Mumbai Capital
motor Hyundai Motor India's ₹27,870 crore IPO subscribed 9% so far on Day 1 By www.thehindu.com Published On :: Tue, 15 Oct 2024 13:06:34 +0530 This is the largest IPO in India, surpassing LIC's initial share sale of ₹21,000 crore. Full Article Markets
motor Hyundai Motor India's record ₹27,870 crore IPO fully subscribed By www.thehindu.com Published On :: Thu, 17 Oct 2024 14:17:57 +0530 The ₹27,870 crore initial share sale got bids for 14,07,68,187 shares against 9,97,69,810 shares on offer, translating into 1.41 times the subscription, as per NSE data till 13:21 hours Full Article Markets
motor Hyundai Motor India’s IPO sees muted response from retail investors, issue subscribed 2.37 times By www.thehindu.com Published On :: Thu, 17 Oct 2024 21:39:24 +0530 The IPO received lowest retail subscription among some of the big IPOs that had hit the Indian capital markets Full Article Markets
motor Hyundai Motor India debuts at BSE at a discount of 1.48%, falls nearly 6% post listing By www.thehindu.com Published On :: Tue, 22 Oct 2024 10:15:03 +0530 This is the biggest ever IPO to have ever hit in the Indian capital markets Full Article Business
motor Hyundai Motor India shares jump 6% By www.thehindu.com Published On :: Wed, 23 Oct 2024 12:43:08 +0530 Hyundai shares climbed 5.91% to ₹1,928.15 from the previous close on the BSE. At the NSE, the stock surged 6% to ₹1,928.90 Full Article Markets
motor Individual Closed-Loop Control of Micromotors by Selective Light Actuation By pubs.rsc.org Published On :: Soft Matter, 2024, Accepted ManuscriptDOI: 10.1039/D4SM00810C, Communication Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.David Rivas, Max Sokolich, Sambeeta DasControl of individual micromotors within a group would allow for improved efficiency, greater ability to accomplish complex tasks, higher throughput, and increased adaptability. However, independent control of micromotors remains a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
motor Man arrested and 20 stolen motorcycles worth ₹15 lakh recovered in Nandyal By www.thehindu.com Published On :: Mon, 11 Nov 2024 20:52:54 +0530 Full Article Andhra Pradesh
motor Anantapur enforcement dirve: police register over 3,000 cases against violators of Motor Vehicle Act By www.thehindu.com Published On :: Tue, 12 Nov 2024 20:47:45 +0530 In the drive conducted over one week, police register 12 cases against gambling dens, arrest 59 persons and seize more than ₹1.91 lakh cash, says SP P. Jagadeesh Full Article Andhra Pradesh
motor Norton Motorcycles announces top level changes By www.thehindu.com Published On :: Mon, 11 Nov 2024 22:19:04 +0530 Full Article Business
motor Tata Motors Q2 consolidated net profit declines 11% to ₹3,343 crore By www.thehindu.com Published On :: Fri, 08 Nov 2024 16:43:46 +0530 The company had posted a consolidated net profit of ₹3,832 crore in the same quarter of the last fiscal, Tata Motors said in a regulatory filing. Full Article Industry
motor Maruti, Hyundai, Tata Motors report decline in wholesales in September By www.thehindu.com Published On :: Wed, 02 Oct 2024 02:12:00 +0530 Mahindra & Mahindra said its SUV wholesales in the domestic market increased 24% to 51,062 units in September compared to the same month of last year Full Article Economy