live System and method for content-based navigation of live and recorded TV and video programs By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system, method and computer-readable medium are presented for providing real-time content-based navigation of live video programming. The video programming is received and a searchable database is generated. The method aspect of the invention comprises receiving a live video program, generating an index to the received live video program by extracting images and/or text from the video program, recording the live video program, presenting at least a portion of data associated with the generated index to a user, receiving user input regarding a search to a portion of the recorded video program to which the user desires to navigate and playing back the recorded video program starting at the searched portion identified by the user input. The search may be of an image and/or text portion of the presentation. Full Article
live Device and method for delivering shape-memory staples By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT An apparatus comprising a plurality of chambers for receiving an associated plurality of staples, each formed with a shape memory that allows the staple to adopt a straightened configuration, when placed in a stapler, and a deployed configuration for suturing when released from the stapler; and a sleeve moveable relative to the chambers between a first position, in which the staples are trapped by the sleeve within the chambers in the straightened configuration, and a second position, whereby the staples are freed to adopt the deployed configuration, wherein the sleeve is adapted to move between the first and second positions by rotating relative to the chambers. Full Article
live Methods and apparatus having bowstring-like staple delivery to a target tissue By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT Devices for attaching a sheet-like implant to a target tissue include a sheath and a staple push rod. The sheath has a distal end configured to be pressed against the target tissue. The staple push rod is disposed within at least a portion of the sheath and is slidable relative thereto. The staple push rod includes a pair of stakes. Each stake is dimensioned to abut a surface of a staple to apply pushing forces thereto. The stakes are biased to assume a bow-like shape such that an intermediate portion of a staple extends tautly between the first stake and the second stake when the stakes are extending beyond the distal end of the tubular member. Methods for attaching a sheet-like implant to a target tissue are also disclosed. Full Article
live Drug-transfer device, drug-delivery system incorporating the same, methods of fabricating the same, and methods of enabling administration of a drug By www.freepatentsonline.com Published On :: Tue, 20 Nov 2012 08:00:00 EST Devices capable of deterring or preventing bulk extraction of drugs from, for example, drug-delivery systems are exemplarily disclosed. In one embodiment, such a device may include a package releasably retaining a drug and an agent. The agent is configured to suppress a physiological effect of the drug when the agent contacts the drug or is coadministered with the drug. The cell package is configured such that an amount of the drug is selectively releasable with respect to the agent when the package is operably proximate to an encoded key. The package, however, may be configured to impose a relatively high likelihood that either the drug will not be accessed or the drug will be contaminated by the agent if access to the contents of the package is sought without the use of an encoded key. Full Article
live Drug-transfer device, drug-delivery system incorporating the same, methods of fabricating the same, and methods of enabling administration of a drug By www.freepatentsonline.com Published On :: Tue, 27 Nov 2012 08:00:00 EST A method of enabling administration of a drug includes determining, within a drug-transfer device including cells, a location of at least one cell and generating information identifying the determined location. A user may be provided with the drug-transfer device. The drug is retained within the at least one cell when the user is provided with the drug-transfer device. The method also includes encoding a key with the information and providing the user with the key before, after or when the user is provided with the drug-transfer device. Drug retained within the at least one cell is selectively releasable when the key is operably proximate to the drug-transfer device and is encoded with the information. The key can be encoded with the information before and/or after being provided to the user. In some embodiments, the key is encoded based on instructions transmitted over a network. Full Article
live Dry food product containing live probiotic By www.freepatentsonline.com Published On :: Tue, 07 Jul 2015 08:00:00 EDT The disclosure relates to a probiotic delivery system that can be consumed as a snack-food or added to a food product. In particular, the disclosure describes a crisp and tasty treat that comprises viable probiotic microorganisms preserved in a vacuum dried matrix of sugars, proteins, and polysaccharides. The probiotic remain viable within the treat for a longer time without the need for additional moisture barrier coating. The probiotic also remain viable in the animal gastrointestinal tract. Full Article
live System and methods for detecting liver disease By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A noninvasive, quantitative imaging technique is presented for detecting and diagnosing liver disease, such as cirrhosis. The technique includes: capturing scan data from a subject using computed tomography or another type of imaging method and extracting image data representing the liver from the scan data. Various measures of the liver may be obtained from image data and then used to compute random variables of a statistical model, where the model is predictive of a medical condition of the liver and comprised of random variables that are indicative of at least one of a shape or texture of the liver. Output from the statistical model provides an indication of an undesirable condition of the liver. Full Article
live Computing cloud system for object selection, object picking by line, object loading and object delivery using an object location identification trigger By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A cloud computing system for object location, object identification, object picking, object picking by line, object loading onto one or more transport devices, or object delivery that can include using a cloud based server comprising a cloud based processor in communication with a cloud based data storage. The cloud based server can be in communication with at least one mobile processor in communication with a mobile data storage and a display. The method can also include sending instructions to an operator from the cloud based computer to a mobile processor associated with an operator to instruct the operator to perform a logistics operation. The logistic operation can include one or more of object location, object identification, object picking, object picking by line, object loading onto one or more transport devices, and object delivery. Full Article
live Battery power delivery module By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A system and method for digital management and control of power conversion from battery cells. The system utilizes a power management and conversion module that uses a CPU to maintain a high power conversion efficiency over a wide range of loads and to manage charge and discharge operation of the battery cells. The power management and conversion module includes the CPU, a current sense unit, a charge/discharge unit, a DC-to-DC conversion unit, a battery protection unit, a fuel gauge and an internal DC regulation unit. Through intelligent power conversion and charge/discharge operations, a given battery type is given the ability to emulate other battery types by conversion of the output voltage of the battery and adaptation of the charging scheme to suit the battery. Full Article
live Water delivery system and method for making hot water available in a domestic hot water installation By www.freepatentsonline.com Published On :: Tue, 13 Jan 2015 08:00:00 EST A water delivery system is provided, comprising at least one faucet device with a cold water faucet part and a hot water faucet part, a cold water line to the at least one faucet device, a tankless heater device for heating water, a hot water line having a first portion running from an outlet of the tankless heater device to the at least one faucet device and having a second portion running from the at least one faucet device to an inlet of the tankless heater device, and a circulatory pump arranged in the second portion of the hot water line, wherein the circulatory pump has a prefixed first performance level and a prefixed second performance level, wherein the first performance level causes a finite water flow in the hot water line which is below an operation threshold value of the tankless heater device. Full Article
live Livestock guide and manipulator By www.freepatentsonline.com Published On :: Tue, 05 Dec 1978 08:00:00 EST A livestock guide and manipulator panel prod is disclosed by this invention wherein electronic shocking circuitry is provided in combination with a hand-held livestock guiding and directing panel having electronic prods of said circuitry arranged on the surface of the panel. Full Article
live Electrified livestock controller By www.freepatentsonline.com Published On :: Tue, 05 Mar 1991 08:00:00 EST An electrified livestock controller for guiding animals, preferably pigs, doubles as a gate and a prod. The controller comprises a central panel of generally planar dimensions, comprising a plurality of central, vertically disposed ribs separated from one another by elongated slots. One or more similar accessory panels are hingedly connected to each side of the central panel. The hinge structure facilitates adjustment of the controller for deployment in a variety of configurations. The hinge structure comprises a detent system having a plurality of indexing disks which, when yieldably mated together, facilitate positioning of the panels in a custom configuration. Suitable flush mounted electric strips are defined on all of the ribs, to provide a shocking effect without tissue damage. The system includes a removable cattle prod which, besides functioning as a handle, can be withdrawn from the handle to separately prod animals. Either concurrently with or independently of rib electrification, audio and/or visual effects may be generated to cause Pavlovian conditioning in the animals. A preferred visual effect of ascending motion, which may be induced by a revolving curtain displaying a spiral image, motivates the animals like a prod. The curtain is best operatively disposed behind the vertical ribs of at least one of the panels. Full Article
live Device for handling livestock using vibration and noise as a stimulation on external portions of the body By www.freepatentsonline.com Published On :: Tue, 08 Oct 2002 08:00:00 EDT A battery operated hand held device for use in handling or controlling livestock, particularly cattle, swine, sheep and horses. This invention provides a novel alternative to conventional electric livestock prods, which deliver an electric shock to the animal. While operating on the principle of external stimulus to invoke a flight response, this invention relies on vibration and/or sound rather than painful electric shock. This unique mode of action satisfies the needs in the livestock industry for low stress handling equipment and techniques with the welfare of the animal as a priority. Full Article
live Audible prod for livestock By www.freepatentsonline.com Published On :: Tue, 03 Jul 2012 08:00:00 EDT A device designed to prod livestock is intended to create an audible sound to aid in the controlled movement of animals. The device takes the form of a long pole comprising an upper end provided with a comfortable handle and a wrist strap and a lower end provided with a whistle. To use, the user would hold the device by the handle in one hand and whip it in a fast, circular motion, causing the whistle to make a sound. When done near an animal, the sound will cause the animal to move away, thus allowing the user to control the movement of the animal. The device is suitable for use by farmers, ranchers, auctioneers, herdsmen, or anyone who loads or moves livestock. Full Article
live Automated lumber retrieval and delivery By www.freepatentsonline.com Published On :: Tue, 24 Feb 2015 08:00:00 EST An automated lumber handling system laser-scans the top profile of multiple stacks of lumber, each of which contain boards of a unique size. Based on the scanned profiles, the system determines the order in which individual boards from a chosen stack should be transferred to a numerically controlled saw. The saw cuts the boards to proper size, and in the proper sequence to facilitate orderly assembly of a roof truss or prefabricated wall. In some examples, the system lifts individual boards by driving two retractable screws, or some other piercing tool, down into the upward facing surface of the board. A track mounted cantilever, holding the screws and a laser unit, translates over the lumber stacks to retrieve and deliver individual boards and, while doing so, the laser repeatedly scans the stacked lumber profiles on-the-fly to continuously update the profiles. The open cantilever design facilitates replenishing the stacks of lumber. Full Article
live System and method for coordinating product delivery with ground engaging tool position By www.freepatentsonline.com Published On :: Tue, 25 Nov 2014 08:00:00 EST An agricultural implement system that includes a control system configured to receive a first signal to initiate seeding operations, to transition a ground engaging tool toward a working position at a first time after receiving the first signal, and to activate a product delivery system at a second time, different from the first time, after receiving the first signal. Full Article
live Central product delivery system By www.freepatentsonline.com Published On :: Tue, 25 Nov 2014 08:00:00 EST A stack-fold implement having a central bulk fill hopper assembly is provided. The bulk fill hopper assembly is mounted to the center frame section of the stack-told implement and does not affect the narrowness of the stack-fold implement when it's in a stacked, transport position, The hopper assembly includes a pair of bulk fill hoppers or tanks supported by cradle that is in turn supported by a pair of wheels. The cradle is removably coupled to the center frame section by a plurality of rigid frame members. Full Article
live Seed delivery apparatus for a farm implement By www.freepatentsonline.com Published On :: Tue, 13 Jan 2015 08:00:00 EST A seed metering assembly for a farm implement has a meter roller that can be accessed and removed in a relatively quick manner. The seed metering assembly includes a fluted meter roller that is segmented into a number of discrete fluted sections. Each fluted section has an associated flow control member that is selectively operable to impede the flow of granular material from a seed hopper to its corresponding section of the fluted meter roller. Full Article
live Seed delivery apparatus, systems, and methods By www.freepatentsonline.com Published On :: Tue, 24 Mar 2015 08:00:00 EDT Referring to the drawings, wherein like reference numerals designate identical or corresponding parts throughout the several views, FIG. 1 illustrates a side elevation view of a single row unit (10) of a conventional row crop planter such as the type disclosed in U.S. Pat. No. 7,438,006, the disclosure of which is hereby incorporated herein in its entirety by reference. As is well known in the art, the row units (10) are mounted in spaced relation along the length of a transverse toolbar (12) by a parallel linkage (14), comprised of upper and lower parallel arms (16, 18) pivotally mounted at their forward ends to the transverse toolbar (12) and at their rearward end to the row unit frame (20). Full Article
live Fluid delivery system for an agricultural implement By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT An agricultural implement is provided that includes a first tool bar and a second tool bar each supporting respective ground engaging tools and fluid dispersal components. The second tool bar is pivotally coupled to the first tool bar. The agricultural implement further includes fluid conduits coupled to respective tool bars for conveying fluid to the respective fluid dispersal components. Additionally, each of the conduits has a flexible end adjacent to the other tool bar. Furthermore, the agricultural implement includes a fluid joint coupled between the first and second flexible ends and configured to provide a sealed connection between the first and second flexible ends during relative pivotal movement of the first and second tool bars in operation but to allow for uncoupling of the first and second flexible ends for servicing of the implement. Full Article
live Reciprocating piston compressor with delivery rate control By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT In a reciprocating piston compressor with delivery rate control, the electromagnetic actuating device (3) of the valve lifter (2) has a separate positioning drive (10) for adjusting the working stroke range of the magnetic actuator (5) used, whereby this can be chosen to be small and highly dynamic and only low power losses occur. Full Article
live Piston ring with improved lubrication delivery By www.freepatentsonline.com Published On :: Tue, 12 May 2015 08:00:00 EDT A piston ring has a body member for sitting in a ring groove of a piston. The body member has an inner periphery, upper wall, lower wall and an outer periphery. The outer periphery has a concavity therein for storing lubricant therein. The upper wall has an outer section proximate to the outer periphery is constructed to be resiliently flexible between a flexed and unflexed position such during a portion of a power stroke, the volume of the concavity to store the lubricant is decreased by the flexing of the upper wall to the flexed position for expelling lubricant therefrom to a wall of the cylinder. The wall resiliently returns to the unflexed position during other times to allow excess lubricant from the wall of the cylinder to pass into the concavity. Full Article
live Chemical delivery system By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT Embodiments of chemical delivery systems disclosed herein may include an enclosure; a first compartment disposed within the enclosure and having a plurality of first conduits to carry a first set of chemical species, the first compartment further having a first draw opening and a first exhaust opening to facilitate flow of a purge gas through the first compartment; and a second compartment disposed within the enclosure and having a plurality of second conduits to carry a second set of chemical species, the second compartment further having a second draw opening and a second exhaust opening to facilitate flow of the purge gas through the second compartment, wherein the first set of chemical species is different than the second set of chemical species, and wherein a draw velocity of the purge gas through the second compartment is higher than the draw velocity of the purge gas through the first compartment. Full Article
live Target delivery device By www.freepatentsonline.com Published On :: Tue, 14 Apr 2015 08:00:00 EDT The present invention relates to a device for delivering targets (2) comprising at least one column (4) for storing targets (2) capable of receiving a first target (11) at the lowest point of the column (4) and at least a second target (12) stacked on the first target (11), means for delivering the first target (11), and retention means for retaining the second target (12) in the column (4), characterized in that the retention means for retaining comprise a ramp (21) configured to exert a bearing force on the lower face of the second target (12) during the delivery of the first target (11). This invention also relates to a machine for launching targets (2) equipped with a device and a method for distributing the targets (2). Full Article
live Method of conditioning a body of water by delivering different dispersant combinations through a floating generally spherical dispenser system By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A dispenser system for delivering various combinations of dispersants to a body of water with the various combinations of dispersants supplied to the body of water through the interchanging of dispensing cartridges which are attachable to a main dispensing cartridge where a condition for interchanging of dispensing cartridges may be triggered by an event. Full Article
live Fluid delivery system and method By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A method of controlling a fluid delivery machine configured to deliver fluid on a worksite is disclosed. In the method, operation of a power source of the fluid delivery machine is controlled with a control module. Fluid delivery on the worksite is also controlled by the control module. Full Article
live Reductant delivery unit for automotive selective catalytic reduction with gasket anti-deposit shielding structure By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT A reductant delivery unit (10) includes a fluid injector (12) and a flange (20) coupled with the fluid injector. An exhaust boss (28) has a surface (39) defining a through-hole (40) that communicates with a vehicle's exhaust flow path. The flange is coupled to a mounting surface such that the outlet of the fluid injector communicates with the exhaust flow path so as to control injection of urea solution into the exhaust gas flow path. A gasket (32) is sandwiched between the flange and the mounting surface. The gasket has a surface (37) defining a through-hole (38) therein that communicates with the through-hole in the exhaust boss to permit the urea solution to pass from the fluid outlet to the exhaust flow path. Gasket shielding structure (44) covers the surface defining the through-hole in the gasket to prevent the urea solution from contacting the gasket. Full Article
live MAINTAINING DEPLOYMENT PIPELINES FOR A PRODUCTION COMPUTING SERVICE USING LIVE PIPELINE TEMPLATES By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT Techniques are presented for managing a deployment pipeline using an inheritable and extensible source code template—generally referred to as a live pipeline template (LPT). As described, live pipeline templates may be used to manage deployment pipelines which, in turn, are used to launch, maintain, and update the services and systems used to host and provide computing services. Full Article
live MANAGING CHANGE-SET DELIVERY By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT An approach that analyzes and manages unresolved (i.e., pending, outgoing) change-sets is provided. Specifically, this approach parses the change-set into a plurality (i.e., one or more) of changes having interdependencies within a java class file to determine the impact each change may have. More specifically, a change-set management tool provides this capability. The change-set management tool includes a parsing module configured to receive an outgoing change-set and to parse the change-set into a plurality of changes having interdependencies within a java class file. The change-set management tool further comprises an evaluation module configured to evaluate an impact that each of the plurality of changes within the change-set has on source code external to the change-set in the java class file based on the interdependencies. Full Article
live ANALYZING DEPLOYMENT PIPELINES USED TO UPDATE PRODUCTION COMPUTING SERVICES USING A LIVE PIPELINE TEMPLATE PROCESS By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT Techniques are presented for managing a deployment pipeline using an inheritable and extensible source code template—generally referred to as a live pipeline template (LPT). As described, live pipeline templates may be used to manage deployment pipelines which, in turn, are used to launch, maintain, and update the services and systems used to host and provide computing services. Full Article
live DEVELOPMENT, DELIVERY, DEPLOYMENT AND OPERATION OF AN APPLICATION By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A system for development, deliver, deployment and operation of an application includes at least one memory including instructions on a computing device and at least one processor on the computing device. The processor is operably coupled to the at least one memory and is arranged and configured to execute the instructions that, when executed, cause the processor to implement an application within a platform associated with a namespace for the platform, where the platform is one platform of a plurality of platforms. The processor implements a descriptor having an identifier that uniquely associates the descriptor with the application, where the descriptor comprises a single file that is platform independent and that includes a plurality of namespaces and application-specific attributes for each of the namespaces to enable the application to operate on multiple different platforms using the same descriptor. Full Article
live Turbomachine fluid delivery system By www.freepatentsonline.com Published On :: Tue, 17 Mar 2015 08:00:00 EDT An exemplary system for delivering a turbomachine fluid to a supplied area is a pump configured to draw fluid from both a first container and a second container when operating in both a positive g-force environment and a negative g-force environment. The fluid from the first container in a positive g-force environment is a mixture of air and oil, and the fluid from the first container in a negative g-force environment is primarily oil. Full Article
live Method and Apparatus for Tuning USB Power Delivery Signals By www.freepatentsonline.com Published On :: Thu, 22 Jun 2017 08:00:00 EDT A USB interface to provide power delivery negotiated through a dedicated transmission channel includes a transmitter circuit including a digital-to-analog converter having an output coupled with an input of a transmission filter, a receiver circuit including an analog-to-digital converter having an input coupled with an output of a receiving filter, and a switching circuit configured in an operating mode of the USB interface to connect an output of the transmission filter and an input of the receiving filter to a connection node of the dedicated transmission channel. Full Article
live Precision water jet disruptor delivery system By www.freepatentsonline.com Published On :: Tue, 25 Mar 2014 08:00:00 EDT A precision coaxial water jet disruption explosive device system that holds a blasting cap precisely to the surface of a cylindrically cut positioned plastic explosive that couples a detonation shock wave into water surrounding a hollow forming cavity. A pressure relief vent enables the water filled system to be assembled without deforming the thin walled hollow jet forming cavity, enabling forming repeatable supersonic jets on centerline axis. This system is positioned with two triangular pivot legs and aligned with two fan light beams or a line sight to define a projected jet route to deliver a water jet that can cut through over 1 inch of steel and disrupt target objects more than 9 feet away. This system is used to disable improvised explosive devices, and other dangerous objects, without detonating the targeted explosives and electronic devices such that the contents are destroyed without explosion sequences occurring. Full Article
live Mobile platform for the delivery of bulk explosive By www.freepatentsonline.com Published On :: Tue, 10 Feb 2015 08:00:00 EST The present invention is directed to a mobile platform for the delivery of bulk explosives to a blast hole. One embodiment of the platform provides the ability to obtain weight information relating to the contents of a tank that is associated with the platform and that, in operation, contains either the bulk explosive or a constituent of the explosive. The platform comprises a vehicle with a frame, a tank, a load cell structure for connecting the frame and the tank and providing weight data relating to the contents of the tank, and a suspension system that prevents relative movement of the frame and the tank that could compromise the load cell structure. Another embodiment of the platform provides a tank for holding an explosive composition and a rotary shaft that supports a mixing blade that mixes the explosive composition within the tank. The platform further comprises bearing structure for supporting the rotary shaft that is located to deter any of the explosive composition from entering the bearing. A further embodiment of the platform comprises a conduit structure for discharging a bulk explosive into a blast hole that includes a substantially rigid tube with an outlet port for discharging a bulk explosive into the blast hole. The tube is adapted to rotate about a vertical axis such that the outlet port can be moved towards and away from the vehicle along an arc of less than 180°. In one embodiment, the outlet port can be positioned substantially adjacent to an operator's station to allow an operator to readily view the loading of the explosive into the blast hole. Full Article
live Pump for delivering flux to molten metal through a shaft sleeve By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT A pump for pumping molten metal and delivering flux includes a refractory base that can be submerged in molten metal including an impeller chamber, an inlet and an outlet. A refractory shaft sleeve has upper and lower end portions and is fastened to the base at the lower end portion. A motor is disposed near the upper end portion of the shaft sleeve. A refractory shaft extends in the shaft sleeve and is connected to the motor near the upper end portion of the shaft sleeve. A refractory impeller is connected to the shaft and is rotatable in the impeller chamber. A flux feeding device feeds flux into the shaft sleeve. Also featured is a method for delivering flux in the shaft sleeve of the pump and a method for cleaning flux accretions in the shaft sleeve. Full Article
live Flavored straw with a flavor delivery system By www.freepatentsonline.com Published On :: Tue, 28 Apr 2015 08:00:00 EDT A beverage flavoring apparatus comprising of an elongated tubular body, having at least three elongated hollow sections and a container for holding liquid flavor. The top hollow section is for suction and at least one of the hollow sections is adapted to receive liquid flavor and it has a smaller cross sectional area and shorter length which enables the flavoring liquid to be introduced into the beverage stream in minute quantity. The other hollow section is adapted to receive beverage. The container is mounted or loaded on the elongated tubular body so that the section adapted to receive liquid flavor is immersed in the liquid flavor while the other hollow section is dipped in a beverage. As oral suction is being applied, both the liquid flavor and the beverage are drawn up the tubular body and mixes at the hollow suction end before ingestion. Full Article
live Novel method for preparing pH dependent Ultra Small Polymeric Nanoparticles for topical and/or Transdermal delivery By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT The invention provides a new method for preparing ultra-small polymeric-lipidic delivery nanoparticles (USDNs) that were synthesized by a nanoprecipitation method followed by a layer-by-layer nanodeposition. The USDNs particle size can be controlled between 5-25 mn and provides loading capacities of 22.12% to 72.08%. Moreover, the USDNs platform provides pH controlled drug release, within a terminal release ratio of 68% at pH 5.0 and almost no release to pH of 7.5. Furthermore, based on their small sizes (5-25 nm) and unique composition, the USDNs penetrates the skin strata efficiently, release the payload at the target site as topical or transdermal treatment of a variety of skin disorders. Additionally the USDNs system can be used to treat and diagnoses other crucial diseases (Cancer, Alzheimer, etc) can be combined with various micro-needles or needles free array technologies for special application. Full Article
live Drug Delivery Enhancement Agents By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A peptide comprising a sequence for opening a tight junction of an epithelial surface and optionally a cell penetrating sequence; and related compositions, optionally comprising further pharmaceutical agents; and related methods. Full Article
live MOLECULAR SIGNATURES FOR DISTINGUISHING LIVER TRANSPLANT REJECTIONS OR INJURIES By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT By a genome-wide gene analysis of expression profiles of known or putative gene sequences in peripheral blood and biopsy samples, the present inventors have identified a consensus set of gene expression-based molecular biomarkers for distinguishing liver transplantation patients who have Acute Rejection (AR), Hepatitis C Virus Recurrence (HCV-R), both AR/HCV-R, or Acute Dysfunction No Rejection (ADNR). These molecular biomarkers are useful for diagnosis, prognosis and monitoring of liver transplantation patients. Full Article
live NUTRIENT DELIVERY SYSTEM COMPRISING NUTRITIONAL POWDER COMPRISING PHOSPHOLIPIDS TO IMPROVE WETTABILITY By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Disclosed herein is a nutrient delivery system that provides a nutritional formula for consumption. The nutrient delivery system includes a pod and a nutritional powder comprising at least one phospholipid. The nutritional formula has improved characteristics, such as decreased foaming. Full Article
live Method, baffle free angle adjustable apparatus and system for delivering dry bulk-free flowing material into a container By www.freepatentsonline.com Published On :: Tue, 21 Oct 2014 08:00:00 EDT A system and method for changing a flow rate and direction of dry bulk material supplied from an elevated source, via an angled spout to an adjustable spout end having no internal baffles therein and having readily interchangeable wear pads therein which are accessible through an access door. Full Article
live Flow-retarding chutes and spouts and method for delivering dry bulk free-flowing material to a location By www.freepatentsonline.com Published On :: Tue, 03 Mar 2015 08:00:00 EST A system and method for causing a differential flow rate to exist in a downspout so as to reduce abrasion of a bottom side of said downspout and to sort dry bulk material flowing therethrough. The present invention reduces the velocity of the mass of the dry bulk material, such as corn, thus preserving grain quality and reducing the exit velocity at the lower end of the spout. Full Article
live Device for collapsing and loading a heart valve into a minimally invasive delivery system By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT A device is provided for collapsing a stented bioprosthetic valve, including first section and second sections, each spanning between first and second ends of the device. The second section of the device is associated with the first section to at least partially enclose an internal cavity formed by the first and second sections, the internal cavity tapering from an open insertion portion at a first end of the device to an open exit portion at a second end of the device. The insertion portion has a larger dimension than the exit portion. When the first section and second section are substantially enclosing the internal cavity, a stented bioprosthetic valve may be inserted into the insertion portion and collapsed as it is moved toward and through the exit portion. The valve may then be loaded on an apparatus for insertion into the body. Full Article
live Smoking article with flavor delivery system By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT A flavor delivery release system for a cigarette or cigarette package. The system includes a cigarette, at least one capsule containing a flavorant, the capsule positioned on an external surface of the cigarette; and wherein the flavorant is released upon rupturing the capsule. Full Article
live Method for forming a smoking article capable of delivering flavorant to mainstream smoke when ignited during smoking By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT Delivery of additives in a smoking article is provided through thermally degradable, robust immobilized additive inserts. Additives can be immobilized in an elongated device or an insert, wherein the elongated device or the insert is sufficiently robust to allow the elongated device or the insert to be manually or machine inserted into a smoking article while maintaining the structure of the elongated device or the insert. By providing additives in the form of thermally degradable immobilized additive inserts, migration and/or loss of the additives in a smoking article prior to smoking can be reduced. Full Article
live Fastening structure of fuel delivery pipe and cylinder head of internal combustion engine By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A fastening structure of a fuel delivery pipe and a cylinder head of an internal combustion engine includes three or more bosses provided on each of the cylinder head and the fuel delivery pipe, and fastening portions formed by bolting the bosses on the cylinder head to the bosses on the fuel delivery pipe. The fastening portions at both end portions of the fuel delivery pipe are less rigid than one or more fastening portions in a middle between the fastening portions positioned at both end portions of the fuel delivery pipe. Full Article
live MOUTHPIECE DELIVERY APPARATUS AND METHODS OF USING THE SAME By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT A mouthpiece delivery apparatus and methods for the using the same are provided. In at least one specific embodiment, the mouthpiece delivery apparatus can include: a mouthpiece that can include a top receiving wall, a bottom receiving wall, a first side wall and a second side wall, where the bottom receiving wall can include a base member and an edge member; an adapter section, where the adapter section is configured to attach to a dispensing apparatus; and a body section, where the body section is attached to the mouthpiece at a first end and attached to the adapter section at a second end. Full Article
live Delivery particle By www.freepatentsonline.com Published On :: Tue, 10 Mar 2015 08:00:00 EDT The present application relates to encapsulated benefit agents, compositions comprising such encapsulated benefit agents and processes for making and using compositions comprising such encapsulated benefit agents that do not require or require a reduced amount of scavenger materials. Such encapsulated benefit agents, compositions comprising such encapsulated benefit agents are processed such that no or lower levels of scavenger materials are required. Full Article
live Protective garment for livestock By www.freepatentsonline.com Published On :: Tue, 27 Nov 2012 08:00:00 EST A protective garment for livestock, such as a horse, has a first portion and a second portion defining a planar sheet of material. The first portion substantially covers a left leg and shoulder of the livestock, while the second portion substantially covers a right leg and shoulder of the livestock. The garment can comprise a one-piece protective cover or a two-piece protective cover. In one embodiment, the first portion and the second portion are connected to each other by an attachment member extending across a back of the livestock. In use, the protective garment is sufficiently secured to the livestock to protect it from undesirable external elements, such as insects and sunlight, yet somewhat loose to allow the livestock to freely move while wearing the garment. Full Article