RSI said single-player Star Citizen campaign was "feature complete" a year ago.

Starring Ashika Ranganath as the female lead, the film is directed by N Rajasekar of ‘Maapla Singam’ and ‘Kalathil Sandhippom’ fame

This follow-up to last year’s ‘Mission: Impossible — Dead Reckoning Part One’, which earned over $571 million globally, is expected to draw blockbuster attention as one of the summer’s biggest releases

Although Avneet hasn’t confirmed any involvement in the film, fans are hopeful this could mark her Hollywood debut, following in the footsteps of Anil Kapoor, who appeared in ‘Mission: Impossible — Ghost Protocol’ in 2011

Canada will be without captain Alphonso Davies for its upcoming CONCACAF Nations League quarterfinal against Suriname. Canada Soccer says the Bayern Munich star has withdrawn as a "precautionary measure due to physical fatigue."

Mark Cohon, who brought the CFL back to Ottawa with the Redblacks as CFL commissioner, is joining the new Northern Super League as chair of its board of directors.

Reigning Professional Women's Hockey League MVP and scoring champion Natalie Spooner will miss the start of the regular season for the Toronto Sceptres, GM Gina Kingsbury announced Tuesday on Day 1 of training camp.

CFL commissioner Randy Ambrosie has some friendly advice for his successor: Surround yourself with good people and be open-minded.

Earlier this year, Feral Interactive’s superb iOS version of Alien: Isolation (Free) was updated to change the game’s business model …

Continue reading "‘Alien: Isolation’ for Android Is Now a Free To Start Release Just Like iOS Letting Everyone Try Two Missions for Free"

President-elect Trump has promised mass deportations, including workplace raids like those that took place during his first term at chicken processing plants in rural Mississippi.

Every county in Georgia has certified its general election results. There had been concerns about election certification, but with Donald Trump's victory, those worries have largely gone away.

NPD “restatement” shows consistent spending growth as digital sales dominate.

Gary Lineker is leaving ‘MOTD’ at the end of this season, after a glittering 25-year tenure as the host of the BBC’s flagship football show. Nick Hilton looks back at the pundit’s highs and lows, from predatory striker to top broadcaster and media mogul

J’ai beaucoup de mal à comprendre ce qu’il y a d’étonnant dans le fait que le Canadien soit dernier au classement.

Paris, France (SPX) Nov 03, 2024
ESA's Proba-3 mission, designed to create a solar eclipse in space, is leaving Europe to head to its Indian launch site. The mission's two spacecraft, designed to align precisely in orbit so one will block the Sun for the other, have departed from Redwire Space's facilities in Kruibeke, Belgium. The pair will be transported to the Satish Dhawan Space Centre near Chennai, India, to prepare for th

Depuis quelques années, et avec une plus grande intensité au cours des derniers jours, plusieurs proposent la création d’une commission Parent 2.0.

Des voleurs ont réussi à dérober un guichet automatique en le tirant à travers la devanture vitrée de l’immeuble à l’aide d’un camion.

L’ex-maire, qui a passé cette année le cap des cinq ans depuis son diagnostic, continue de s’impliquer pour sensibiliser les hommes à ce fléau.

Laissez les beaux-pères au chalet et vos candidats libres de vous étonner. S’ils en sont capables, ils le feront.

On apprend aujourd’hui que certains CPE, subventionnés avec votre argent, pratiquent une discrimination scandaleuse dans l’accueil des enfants.

Total greenhouse gas emissions from Alberta's oilsands have remained relatively flat for the last few years but could climb yet again in 2024 as the industry ratchets up oil production, according to a new report released Thursday.

Canada’s privacy commissioner has launched an investigation into the World Anti-Doping Agency (WADA) and “its handling of biological samples collected from athletes.”

Technology differences mean meters in northern England and Scotland may not work properly, energy firm body admits.

Dans une étude, on rapporte qu’un médicament antidiabétique très utilisé retarde les effets négatifs du vieillissement sur les fonctions cognitives.

The Directorate General of Trade Remedies (DGTR), under the Ministry of Commerce and Industry, has issued a notice to all interested parties involved in the sunset review of the anti─dumping investigation

FDA’s mission is “at risk” because of inadequate funding. So says Alliance for a Stronger FDA President Diane Dorman, testifying before the FDA Science Board. Her remarks come 5 years after the Science Board made a similar declaration, concluding that decades of underfunding had left FDA without the resources to fulfill its mandate and make science-based decisions. Congress responded with more monies for the agency, but since then the FDA’s workload has increased even faster. The current threat to FDA comes from two sources: four major new laws to implement since 2009; and changes in the environment in which FDA operates, notably acceleration of globalization and increasing scientific complexity. Ms. Dorman’s remarks are reprinted below. If you care about FDA, FDA Matters urges you to read her testimony, go to the Alliance’s site (www.StrengthenFDA.org) and join.

Starting COVID-19 patients on prophylactic anticoagulation within 24 hours of being admitted to hospital has been linked to a reduced risk of mortality.

When university and hospital trusts were called to the UK parliament last year to answer questions on why they were not following the rules on reporting results, we saw how effective the questioning from politicians was. Those of you who watched the parliamentary session saw the pressure the university representatives were put under. Because the politicians asked […]

In the United States alone, more than 100,000 people currently need a lifesaving organ transplant. Instead of waiting for donors, one way to solve this crisis in the future is to assemble replacement organs with bio-printing—3D printing that uses inks containing living cells. Scientists in Israel have found that origami techniques could help fold sensors into bio-printed materials to help determine whether they are behaving safely and properly.

Although bio-printing something as complex as a human organ is still a distant possibility, there are a host of near-term applications for the technique. For example, in drug research, scientists can bio-print living, three-dimensional tissues with which to examine the effects of various compounds.

Ideally, researchers would like to embed sensors within bio-printed items to keep track of how well they are behaving. However, the three-dimensional nature of bio-printed objects makes it difficult to lodge sensors within them in a way that can monitor every part of the structures.

“It will, hopefully in the future, allow us to monitor and assess 3D biostructures before we would like to transplant them.” —Ben Maoz, Tel Aviv University

Now scientists have developed a 3D platform inspired by origami that can help embed sensors in bio-printed objects in precise locations. “It will, hopefully in the future, allow us to monitor and assess 3D biostructures before we would like to transplant them,” says Ben Maoz, a professor of biomedical engineering at Tel Aviv University in Israel.

The new platform is a silicone rubber device that can fold around a bio-printed structure. The prototype holds a commercial array of 3D electrodes to capture electrical signals. It also possesses other electrodes that can measure electrical resistance, which can reveal how permeable cells are to various medications. A custom 3D software model can tailor the design of the origami and all the electrodes so that the sensors can be placed in specific locations in the bio-printed object.

The scientists tested their device on bio-printed clumps of brain cells. The research team also grew a layer of cells onto the origami that mimicked the blood-brain barrier, a cell layer that protects the brain from undesirable substances that the body’s blood might be carrying. By folding this combination of origami and cells onto the bio-printed structures, Maoz and his colleagues were able to monitor neural activity within the brain cells and see how their synthetic blood-brain barrier might interfere with medications intended to treat brain diseases.

Maoz says the new device can incorporate many types of sensors beyond electrodes, such as temperature or acidity sensors. It can also incorporate flowing liquid to supply oxygen and nutrients to cells, the researchers note.

Currently, this device “will mainly be used for research and not for clinical use,” Maoz says. Still, it could “significantly contribute to drug development—assessing drugs that are relevant to the brain.”

The researchers say they can use their origami device with any type of 3D tissue. For example, Maoz says they can use it on bio-printed structures made from patient cells “to help with personalized medicine and drug development.”

The origami platform could also help embed devices that can modify bio-printed objects. For instance, many artificially grown tissues function better if they are placed under the kinds of physical stresses they might normally experience within the body, and the origami platform could integrate gadgets that can exert such mechanical forces on bio-printed structures. “This can assist in accelerating tissue maturation, which might be relevant to clinical applications,” Maoz says.

The scientists detailed their findings in the 26 June issue of Advanced Science.

BAKU — Global carbon dioxide emissions, including those from burning fossil fuels, are set to hit a record high this year, pulling the world further off course from averting more destructive climate extremes, scientists said on Wednesday (Nov 13). The Global Carbon Budget report, published during the UN's COP29 climate summit in Azerbaijan, said global CO2 emissions are set to total 41.6 billion metric tons in 2024, up from 40.6 billion tons last year. The bulk of these emissions are from burning coal, oil and gas. Those emissions would total 37.4 billion tons in 2024, up by 0.8 per cent in 2023, the report said. The rest are from land use, a category that includes deforestation and forest fires. The report by more than 80 institutions was led by the University of Exeter in UK. "We don't see a sign of fossil fuel emissions peaking in 2024," said lead author Pierre Friedlingstein, a climate scientist at the University of Exeter. Without immediate and steep emissions cuts worldwide, "we will just go straight into the 1.5C target, we'll just pass it and continue," he said.

Dec 5, 2023

David W. Kearn argues that deployment of nuclear weapons cannot rectify a perceived imbalance in conventional forces in the western Pacific.

Sep 28, 2022

As the best documented major crisis in history, in substantial part because Kennedy secretly taped the deliberations in which he and his closest advisers were weighing choices they knew could lead to a catastrophic war, the Cuban missile crisis has become the canonical case study in nuclear statecraft. Over the decades since, key lessons from the crisis have been adapted and applied by the successors of Kennedy and Khrushchev to inform fateful choices.

Oct 27, 2022

Kennedy’s statecraft in the missile crisis provides a rich source of clues that can help illuminate the challenge the United States now faces, and the choices President Joe Biden is making.

In a wide-ranging meeting with CODEL McCaskill February 17, National Security Advisor Shivshankar Menon touched on several regional security and trade-related issues.

Nov 30, 2023

Joseph S. Nye writes that evaluating ethics in international relations is difficult, and Kissinger's legacy is particularly complex. Over his long tenure in government, he had many great successes, including with China and the Soviet Union and the Middle East. Kissinger also had major failures, including in how the Vietnam War ended. But on net, his legacy is positive. In a world haunted by the specter of nuclear war, his decisions made the international order more stable and safer.

Oct 26, 2015

"African leaders would like to escape the colonial trap of being viewed simply as raw material exporters. But their efforts to add value to the materials continue to be frustrated by existing EU policies."

Jul 10, 2023

The Salata Institute for Climate and Sustainability at Harvard University launched today a major research and outreach initiative to reduce global methane emissions. The initiative seeks meaningful and sustained progress in global methane-emissions reductions through research and effective engagement with government policymakers — and with key stakeholders in business, nongovernmental organizations, and international institutions.

Nov 8, 2023

Economic historian Emma Rothschild, the Jeremy and Jane Knowles Professor of History at Harvard, lauded the efforts of young scholars to discover local solutions to mitigate the impacts of global climate change in the latest episode of “Environmental Insights: Discussions on Policy and Practice from the Harvard Environmental Economics Program.” The podcast is produced by the Harvard Environmental Economics Program.

Nov 15, 2023

Efforts around and impacts of global methane-emissions abatement will be the focus at an official side event on December 6 co-sponsored by the Harvard Project on Climate Agreements at the 28th Conference of the Parties (COP-28) of the United Nations Framework Convention on Climate Change (UNFCCC) in Dubai. Harvard Project Director Robert Stavins will also participate in a number of other events at COP-28.

Dec 13, 2023

The Harvard Project on Climate Agreements (HPCA) assembled a panel of leading academics and government officials to discuss strategies for achieving significant methane emissions reductions at relatively low costs at an official COP 28 Side Event last Wednesday (Dec. 6). The event, titled “Reducing Global Methane Emissions: Imperatives, Opportunities, and Challenges,” was moderated by HPCA Director Robert Stavins.

Mar 28, 2024

Many issues in the Arctic are transboundary in nature and cannot be solved at the national level. A study group, led by Arctic Initiative Senior Fellow Margaret Williams, examined several key Arctic issues - maritime safety and security, commercial fisheries, and climate change and energy - and the difficulties of addressing them without Russian involvement.

Feb 2, 2024

Jacqueline L. Hazelton's Bullets not Ballots: Success in Counterinsurgency Warfare (Cornell University Press, 2021) is the subject of a Roundtable Review.

Jul 11, 2024

Efforts to measure and mitigate the impact of methane emissions was the topic of discussion last Monday (June 10, 2024) at a panel convened as part of Climate Action Week in the Northwest Building, sponsored by Harvard’s Salata Institute for Climate and Sustainability and moderated by Harvard Environmental Economics Program and Harvard Project Director Robert Stavins.

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