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India IT spending to reach USD 160 billion in 2025 fueled by application and infrastructure software market growth: Gartner




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Google.org awards USD 1 mn grant to Karya to boost ai-based economic opportunities for low-income communities




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Rajnath Singh stresses on adaptive defence to cope with Age of Grey Zone, hybrid warfare




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‘Anti-war’ comedy play riles Bulgarian nationalists

Last week’s premiere of Arms and the Man by renowned Irish-born playwright George Bernard Shaw sparked raucous protests by nationalist groups




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Cold War-era H-6 bomber enhances China’s ability to strike U.S. bases

The H-6 long-range bomber was used in China’s October war games around Taiwan; it flew close to the U.S. mainland for first time in June




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Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery

RSC Med. Chem., 2024, 15,3695-3703
DOI: 10.1039/D4MD00546E, Research Article
Miyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke Demizu
A novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.
The content of this RSS Feed (c) The Royal Society of Chemistry




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SEIL Energy bags seven awards from QCFI




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Devotees offer special prayers at Sri Kalyana Venkateswara Swamy temple in Srikakulam




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Uncontrolled diabetes increases risk of hearing loss; doctors call for more awareness, screening

Hearing loss occurs twice as frequently in patients with uncontrolled diabetes as compared to the non-diabetic population, doctors say, calling for screening to be included in routine diabetes care




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Watch | War over Waqf: Busting myth and misinformation

How did an incident in a small village in Vijayapura snowball into an issue of national interest?




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Pro Kabaddi League: Gujarat Giants return to winning ways with big win over Bengal Warriorz

In the second match of the night, Haryana Steelers moved to the top of the table and extended their winning run to four games after defeating the Patna Pirates 37-32




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Photographer from Gaza Strip among winners at top photography award in UAE

The Hamdan bin Mohammed bin Rashid Al Maktoum International Photography Award (HIPA) is the richest photography competition in the world.




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Co-Founder of The Banyan bags Sat Paul Mittal National Award




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MRPL gets special award for innovation by Petroleum Ministry




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Android Malware Hidden For Years

Five rogue Android apps remained in the Google Play store for more than two years. They hosted notorious malware called Mandrake that was hidden through some creative means. According to SecureList, the apps were titled AirFS, Amber, Astro Explorer, Brain Matrix and CryptoPulsing. The good news is that the apps had hardly any downloads, one of the reasons they attracted little attention. The real concern is whether malware distributors are using the same tactics with other apps. (Source: securelist.com ) Mandrake has been known about since 2020, though appears to have been in circulation ... (view more)




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Google Warns of 2G SMS Scam

Google has warned Android users to disable 2G connectivity. It says scammers are taking advantage of the outdated tech to send phishing messages and other spam that gets past all filters. 2G cellphone service was commonplace in the 1990s before being followed by 3G in the 2000s. 2G was the beginning of digital mobile phone connections and allowed for SMS text messaging, though it wasn't fast enough to support reliable mobile Internet services. While most US carriers have disabled their 2G networks, many handsets still support it. It can be useful as a last resort in places with either limited ... (view more)




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Ransomware Turns to Triple Threat

A notorious ransomware group has engaged in a "triple threat" attack. As well as locking files and threatening to expose data, the Qilin group has been spotted trying to steal saved passwords from Chrome. The Qilin group appears to have been operating for at least two years but came to wider attention in 2022 when it attacked British hospitals. The group's origins and membership aren't known for certain, but it has communicated in Russian. As is becoming more common, Qilin doesn't simply restrict itself to encrypting files and systems and then demanding a ransom payment to restore access. It ... (view more)




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Necro Malware Infects 'Modified' Spotify, WhatsApp

"Modified" versions of popular apps have helped distribute a nasty piece of Android malware. The tactic expanded the reach of the Necro Trojan despite Google's security checks. Necro was able to survive for some time before discovery, largely because the infection wasn't obvious to users. Its main purpose was to hijack phones and use them to make money for the people behind the malware. This included displaying paid ads in the background so that users didn't see them, but the scammers were able to claim revenue from advertisers. The malware would also install apps on the phone to earn ... (view more)




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A Good And Faithful Steward

Fr. Barnabas welcomes Bill Marianes, Orthodox attorney and stewardship consultant to talk about the stewardship of our personal resources. Bill founded the Stewardship Calling ministry.




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Parenting Toward The Kingdom

Fr. Barnabas welomes Dr. Philip Mamalakis about his new book Parenting Toward The Kingdom, published by Ancient Faith.




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The War on the Hippocratic Oath

Bioethicist and Orthodox Christian Wesley J. Smith joins Fr. Barnabas to discuss medical ethics, end of life issues, and societal trending in the world of bioethics.




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Halloween and Spiritual Warfare

On this episode, Fr. Barnabas welcomes Fr. Lawrence Farley, author of the Bible Study Companion series and teacher on the Coffee Cup Commentaries. They discuss demons, demonology, and Halloween.




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FBI offers $25,000 reward for information on suspect in ballot box fires

The FBI said Wednesday it is offering up to $25,000 as a reward for information about the suspect behind recent ballot box fires in Oregon and Washington state.




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"We Need Everyone": New Award Recognizes the Importance of Scientific Community

In the lab of Minna Roh-Johnson, PhD, great science and great mentorship are inextricable. Now, up to $250,000 in federal funding from the National Cancer Institute has made that philosophy concrete by advancing cancer research and building scientific community.




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Center of the Storm From Lucas Films Star Wars

Center of the Storm From Lucas Films Star Wars by Raymond Swanland is a(n) Limited Edition. The Edition is Limited to Limited Edition Of 10 pcs




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Through the Fire From Lucas Films Star War

Through the Fire From Lucas Films Star War by Raymond Swanland is a(n) Limited Edition. The Edition is Limited to Limited Edition Of 10 pcs




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Stuff That Dreams From Lucas Films Star Wars

Stuff That Dreams From Lucas Films Star Wars by Peter Ferk is a(n) Limited Edition. The Edition is Limited to Limited Edition Of 195 pcs




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Stuff That Dreams From Lucas Films Star Wars

Stuff That Dreams From Lucas Films Star Wars by Peter Ferk is a(n) Limited Edition. The Edition is Limited to Limited Edition Of 245 pcs




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Daily Warm-Up 4 for Gr. 3 & 4: Numbers and Numeration

Use this printable math daily warm-up to reinforce your students' number and numeration skills.




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Daily Warm-Up 4 for Gr. 1 & 2: Numbers and Numeration

Use this printable math daily warm-up to reinforce your students' number and numeration skills.





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Late Ordovician mass extinction caused by volcanism, warming, and anoxia, not cooling and glaciation

Bond, D; Grasby, S E. Geology vol. 48, 2020 p. 1-5, https://doi.org/10.1130/G47377.1
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20200056.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20200056.jpg" title="Geology vol. 48, 2020 p. 1-5, https://doi.org/10.1130/G47377.1" height="150" border="1" /></a>




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CO2 buildup drove global warming, the Marinoan deglaciation, and the genesis of the Ediacaran cap carbonates

Sun, R; Shen, J; Grasby, S E; Zhang, J; Chen, J; Chuang, Y; Yin, R. Precambrian Research vol. 383, 106891, 2022 p. 1-9, https://doi.org/10.1016/j.precamres.2022.106891
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20220487.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20220487.jpg" title="Precambrian Research vol. 383, 106891, 2022 p. 1-9, https://doi.org/10.1016/j.precamres.2022.106891" height="150" border="1" /></a>




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Mercury evidence of Deccan volcanism driving the Latest Maastrichtian warming event

Li, S; Grasby, S E; Zhao, X; Chen, J; Zheng, D; Wang, H; Fang, Y; Zhang, Q; Yu, T; Tian, J; Du, S; Jarzembowski, E A; Wang, Q; Zhang, H; Wan, X; Wang, B. Geology vol. 50, no. 10, 2022 p. 1140-1144, https://doi.org/10.1130/G50016.1
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20220394.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20220394.jpg" title="Geology vol. 50, no. 10, 2022 p. 1140-1144, https://doi.org/10.1130/G50016.1" height="150" border="1" /></a>




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Magma-shale interaction in large igneous provinces: implications for climate warming and sulphide genesis

Deegan, F M; Bédard, J H; Grasby, S E; Dewing, K; Geiger, H; Misiti, V; Capriolo, M; Callegaro, S; Svensen, H H; Yakymchuk, C; Aradi, L E; Freda, C; Troll, V R. Journal of Petrology vol. 63, 2022 p. 1-10, https://doi.org/10.1093/petrology/egac094
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20220242.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20220242.jpg" title="Journal of Petrology vol. 63, 2022 p. 1-10, https://doi.org/10.1093/petrology/egac094" height="150" border="1" /></a>




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Paleoproterozoic dyke swarms and large igneous provinces of northern Canada and their use in understanding extension, rifting, and paleocontinental reconstructions

Buchan, K L; Ernst, R E. Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 375-410, https://doi.org/10.4095/332506
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332506.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_332506.jpg" title="Canada's northern Shield: new perspectives from the Geoscience for Energy and Minerals Program; Geological Survey of Canada, Bulletin 612, 2024 p. 375-410, https://doi.org/10.4095/332506" height="150" border="1" /></a>




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Austrian Post: This partnership is an important step towards improving security

Österreichische Post AG and the Federal Ministry of the Interior (BMI) have launched the strategic security partnership under the title "TOGETHER. SICHER mit der Post".




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DHL Global Forwarding embraces AI

At the recently held myDHLi Digital Summit 2024, DHL presented key improvements and innovations for its myDHLi customer portal along three dimensions: ease of use, resilience and sustainability.




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Bowling: Fight, Warriors, Unpredictable & Mix Win

Mixed majors bowling league action at the Warwick Lanes saw fifth placed Fight Back defeat seventh placed Activators 17 – 3, sixth placed Warriors defeat the league leaders Spare Change 12 – 8, while the eighth placed Movers “N” Shakers lost 14 – 6 to third place Unpredictable, and second placed MiniMax Forwarders went down […]




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An Advance Toward Inhalable mRNA Medications, Vaccines

A study in the Journal of the American Chemical Society reports steps toward making inhalable mRNA medicines a possibility. Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice's lungs.




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A Step Toward Safer X-Rays with New Detector Technology

Now, researchers publishing in ACS Central Science have taken a step toward safer X-rays by creating a highly sensitive and foldable detector that produces good quality images with smaller dosages of the rays.




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Ongoing Drought and Wildfires Across New Jersey and Northeast Lead To Poor Air Quality Warnings

Expert pitch on smoke dangers from wildfires




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Pioneering Research Shows Sea Life Will Struggle to Survive Future Global Warming

A new study highlights how some marine life could face extinction over the next century, if human-induced global warming worsens.




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Catch up on the Future of Warcraft with the Warcraft 30th Anniversary Direct! - Blizzard News

  1. Catch up on the Future of Warcraft with the Warcraft 30th Anniversary Direct!  Blizzard News
  2. Get the Drop on New Rewards During the Warcraft 30th Anniversary Direct  Blizzard News
  3. The Latest World Of Warcraft: Midnight Teaser Implies That Housing Is Coming To The Game  Press Start Australia
  4. All The Major Announcements From The Warcraft 30th Anniversary Direct  Press Start Australia
  5. Warcraft celebrates 30th anniversary by keeping old promises  VentureBeat






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'Warrior Board' Would Make It Easier For Trump To Fire Generals

The Trump team is considering a draft executive order that establishes a “warrior board” of retired senior military personnel *cough*Mike Flynn*cough* with the power to review three- and four-star officers and to recommend removals of any deemed unfit for leadership. What could possibly go wrong? Via the Wall St. Journal:

If Donald Trump approves the order, it could fast-track the removal of generals and admirals found to be “lacking in requisite leadership qualities,” according to a draft of the order reviewed by The Wall Street Journal. But it could also create a chilling effect on top military officers, given the president-elect’s past vow to fire “woke generals,” referring to officers seen as promoting diversity in the ranks at the expense of military readiness.

As commander in chief, Trump can fire any officer at will, but an outside board whose members he appoints would bypass the Pentagon’s regular promotion system, signaling across the military that he intends to purge a number of generals and admirals.

read more




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Chris Evans Is Engaged In Amazing Twitter War With A White Supremacist, and People Are Calling It Most 2017 Thing Ever

It's as if Evans is battling it out with the 'Red Skull' himself. A word to the wise, a Twitter Pro Tip if you will: maybe don't go after Captain America himself, unless you're ready for a solid ass-whooping. 





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Orbitofrontal Cortex Mediates Sustained Basolateral Amygdala Encoding of Cued Reward-Seeking States

Basolateral amygdala (BLA) neurons are engaged by emotionally salient stimuli. An area of increasing interest is how BLA dynamics relate to evolving reward-seeking behavior, especially under situations of uncertainty or ambiguity. Here, we recorded the activity of individual BLA neurons in male rats across the acquisition and extinction of conditioned reward seeking. We assessed ongoing neural dynamics in a task where long reward cue presentations preceded an unpredictable, variably time reward delivery. We found that, with training, BLA neurons discriminated the CS+ and CS– cues with sustained cue-evoked activity that correlated with behavior and terminated only after reward receipt. BLA neurons were bidirectionally modulated, with a majority showing prolonged inhibition during cued reward seeking. Strikingly, population-level analyses revealed that neurons showing cue-evoked inhibitions and those showing excitations similarly represented the CS+ and behavioral state. This sustained population code rapidly extinguished in parallel with conditioned behavior. We next assessed the contribution of the orbitofrontal cortex (OFC), a major reciprocal partner to the BLA. Inactivation of the OFC while simultaneously recording in the BLA revealed a blunting of sustained cue-evoked activity in the BLA that accompanied reduced reward seeking. Optogenetic disruption of BLA activity and OFC terminals in the BLA also reduced reward seeking. Our data indicate that the BLA represents reward-seeking states via sustained, bidirectional cue-driven neural encoding. This code is regulated by cortical input and is important for the maintenance of vigilant reward-seeking behavior.