Boyne Capital, a Miami-based private equity firm, said an affiliate invested in Premier Building Associates, a top commercial roofing firm in New England and No. 100 on RC's 2024 Top 150 list; this is Boyne's second investment in the roofing sector.

This column from Josh Sparks, CEO of Infinity Home Services, is a must-read if you are interested in partnering with a private equity firm to grow your roofing company.

El técnico de Osasuna, tras una semana en Massanassa ayudando a las víctimas de la DANA, regresa a su trabajo para enfrentarse al Real Madrid. Leer

Un comité gestionado por ambas compañías regulará el desarrollo de la arquitectura de los procesadores, la más usada, de momento, en informática. Leer

Coloca de embajadora en la ONU a Elise Stefanik, aliada cercana en el Congreso sin ninguna experiencia en Política Exterior Leer

La víctima es una mujer rusa de 33 años y el presunto autor del crimen es un español de 36 años Leer

Iba para bailarina, pero eligió la arquitectura. Hoy, Lourdes Treviño es una autoridad en la creación de viviendas de alta gama PassivHaus, un sistema de construcción que garantiza un drástico ahorro de energía. Las que ella crea, además, no sacrifican el diseño. La casa de tus sueños sin necesidad de calefacción ni aire acondicionado. Ahí es nada. Leer

El padre aguantó cinco horas agarrado a un árbol hasta que pudieron rescatarle Leer

In a move set to transform the landscape of voice analytics and recording, Micro Plus Software Ltd, operating as Tollring, has entered a strategic equity alliance with Amity Solutions. 

Humans aren’t quite ready for a chatbot takeover, according to a new study

The extent of Arctic sea ice has shriveled to its lowest extent for the year, heralding the end of summer. The ice covers about 750,000 fewer square miles of ocean than average — a testament to continuing climate change.

Location: Electronic Resource- 

Location: Electronic Resource- 

Antiquities under Siege: Cultural Heritage Protection after the Iraq War [Hardcover]

Sarah Borghi women ultra sheer pantyhose. Lycra 6 denier. Treated with natural essences BIO-FRESH, keeping away mosquito and insects with refreshing effects. Includes Hipoallergenic certificate from the Pharmacology Institute of the University of Pavia. Almost transparent ultra sheer for evening wear. Meryl labelled. Cotton gusset. Flat seams. Nude toe. Made in Italy. Colors Naturel,Trianon,Playa,Chiaro,Nero. Sizes 1,2,3. See Sizechart. Price: USD7.47

Krafty Entertainment has acquired a minority equity stake in Sports First TV, the world's first global sports news TV channel. Sports First TV, which launched in March on FAST platforms in North America, was founded by Frank Brown, the former CEO of Viacom International Media/MTV Networks, where he served for 11 years. The channel is based in Sydney, Australia.

Updated at 9:35 p.m. ET Monday The revelation that Fox News prime-time star Tucker Carlson's top writer had posted racist, sexist and homophobic sentiments online for years under a pseudonym has led to renewed scrutiny of Carlson's own commentaries, which have inspired a series of advertising boycotts. The writer, Blake Neff, resigned on Friday after questions raised by CNN's Oliver Darcy led to the posts becoming public. Carlson addressed the controversy on the air Monday night, saying Neff's comments were wrong and "have no connection to the show." After noting Neff had paid the price for his actions, Carlson also spoke about what he called the costs of self-righteousness. "When we pretend we are holy, we are lying," he said. "When we pose as blameless in order to hurt other people, we are committing the gravest sin of all, and we will be punished for it, no question." In an internal memo, Fox News CEO Suzanne Scott and President and Executive Editor Jay Wallace called the postings

Los artistas se presentarán en Bogotá el próximo 13 de septiembre.

Jerome Sanabria, joven de 17 años, habló en Caracol Radio sobre cómo se ha viralizado en redes sociales por su oposición a las reformas del Gobierno

Varios ciclistas del team “Colombia potencia de vida” aseguraron en 6AM que el gobierno Petro los dejó desamparados, les quitaron hasta las bicicletas, y no les pagan desde diciembre, cuando venció el último contrato.

Gabriela Valentín, abogada de Earth-Rights International, explicó a 6AM cuáles son las consecuencias reales ante la decisión del tribunal de EEUU de declarar culpable a la empresa estadounidense por sus nexos con el paramilitarismo.

Luis Eduardo López Rosero, el dueño de la empresa Impoamericana Roger, contratista de los carrotanques de la Guajira, intentó atentar contra su vida.

Deborah Kimmett and Myles Anderson make waves when they discuss if there’s no better day than a day at the beach. Then, are mosquitoes the most annoying insect? Pete Zedlacher and Rob Bebenek get under each other’s skin when they take on these bothersome bugs.

There are many reasons why you might leave your job. You could be bored, not feeling challenged, or perhaps working for a company that no longer aligns with your values. Whether you're considering it, or have already made "the big leap"...what's your story?

Some of the most significant corporate commitments have come from JPMorgan Chase, Microsoft, AMEX, Bank of America, PayPal, Salesforce and Chase.  These large corporate commitments do not account for the other minority-focused investments, such as JP Morgan's initiative to lend more openly to minority owned businesses and black and brown home purchasers.  The corporate giving trend is fueled by changing expectations of younger employees and progressive consumers that expect corporations to become serious about corporate responsibilities to social issues and causes.  Advocates argue that these corporate commitments will not be enough to achieve racial equity in housing, employment and policing, but acknowledge that if these corporations are serious about their commitments, that it can mark an important start.  "'The world is changing, and the expectations of how companies engage are changing,' said Brandee McHale, Citi’s head of community investing and development."

ABC News reports that "[s]ince late May, Grabois said, financial commitments by companies to racial equity causes have grown 'exponentially larger' than any other cause other than COVID-19. A report by McKinsey & Company, which tracked corporate responses from May to October, found that of the top 1,000 U.S. companies, 18% made internal commitments, like diversifying their hiring, and 22% pledged to promote racial equity through donations or other means."

Whether corporate giving to racial equity causes results in systemic change and reform remains to be seen.  Holding corporations to their commitments will likely be an important undertaking.

photo courtesy of wikimedia commons

Stop your self-centered whining, and let’s get on with the job of building more badly needed housing. And thank the Kroenkes’ for investing in Denver’s housing stock.

Parents said the teacher singled Black students out.

Some students have chosen to isolate during the festivities.

The new plan will bring advances to the Black community.

“It was too much,” the gymnast said.

A Bermuda-born man has been cleared of planning a terrorist attack in the United Kingdom following a trial held at the Old Bailey, while his cousin, also born in Bermuda, was cleared of failing to disclose a plot to authorities. A BBC story said, “A former chicken shop worker has been cleared of planning a […]

When I need to replace a swing on my swing set, I don't often come to the conclusion that a helicopter chassis would be better suited for the task, but hey, I'm not everybody I guess.

Or at least switch to 12oz cans to delay the inevitable.

~NSHA

When my job announced we were returning to the office, I was able to quit and rely on my emergency fund while job searching. I still wish I had saved more.

Interactive Media Strategies released data on July 14 showing that 62% of corporations that purchased video communications technology made the decision at the President/CEO level when there was no prior investment in this kind of technology.  That number dropped to 58% when the prior year's spend was as much as $10,000.

The same data shows that when an enterprise already spends $100,000 or more annually on video, the decision-making authority is almost evenly distributed between IT (35%), functional department heads (31%), and the President/CEO level (34%).

I think the clear implication of this data is that when corporations are already committing resources to video communications and the value of video has already been established, and this kind of technology is no longer considered exotic, then decision-making authority becomes more broadly distributed to IT and the business units.

This data is interesting when paired with data released in 2010 that shows 15% of executives surveyed that do not spend money on video and are thus not using video communications believe video communications are "very effective."  58% of executives surveyed that spend $100,000 or more annual on video technology indicated they believe video communications are "very effective."

I am sure this great difference is due to several factors, including: executives who are predisposed to see value in video are those most likely to invest in it, and those that have already made a six figure investment in video will likely not be motivated to feel as if the investment was wasted.  Nonetheless, video obviously wears well because executives who are heavily invested in video believe much more in its value than executives who do not employ the technology.

The QT interval is a recording of cardiac electrical activity. Previous genome-wide association studies identified genetic variants that modify the QT interval upstream of LITAF (lipopolysaccharide-induced tumor necrosis factor-α factor), a protein encoding a regulator of endosomal trafficking. However, it was not clear how LITAF might impact cardiac excitation. We investigated the effect of LITAF on the voltage-gated sodium channel Nav1.5, which is critical for cardiac depolarization. We show that overexpressed LITAF resulted in a significant increase in the density of Nav1.5-generated voltage-gated sodium current INa and Nav1.5 surface protein levels in rabbit cardiomyocytes and in HEK cells stably expressing Nav1.5. Proximity ligation assays showed co-localization of endogenous LITAF and Nav1.5 in cardiomyocytes, whereas co-immunoprecipitations confirmed they are in the same complex when overexpressed in HEK cells. In vitro data suggest that LITAF interacts with the ubiquitin ligase NEDD4-2, a regulator of Nav1.5. LITAF overexpression down-regulated NEDD4-2 in cardiomyocytes and HEK cells. In HEK cells, LITAF increased ubiquitination and proteasomal degradation of co-expressed NEDD4-2 and significantly blunted the negative effect of NEDD4-2 on INa. We conclude that LITAF controls cardiac excitability by promoting degradation of NEDD4-2, which is essential for removal of surface Nav1.5. LITAF-knockout zebrafish showed increased variation in and a nonsignificant 15% prolongation of action potential duration. Computer simulations using a rabbit-cardiomyocyte model demonstrated that changes in Ca2+ and Na+ homeostasis are responsible for the surprisingly modest action potential duration shortening. These computational data thus corroborate findings from several genome-wide association studies that associated LITAF with QT interval variation.

Ivan Matic
Jan 1, 2008; 7:132-144
Research

Tamar Geiger
Mar 1, 2012; 11:M111.014050-M111.014050
Special Issue: Prospects in Space and Time

Sebastian A. Wagner
Oct 1, 2011; 10:M111.013284-M111.013284
Research

Christian Tagwerker
Apr 1, 2006; 5:737-748
Research