As the price of Bitcoin (BTC) recorded a new all-time high of $80,137, the overall cryptocurrency market experienced a massive inflow. The buying pressure was key to the recovery trend witnessed by most altcoins, including Shiba Inu (SHIB), which saw its burn rate surge remarkably.  Shiba Inu Burns Nearly 500M SHIB Coins As Memecoin Surges [...]

U.S. President-elect Donald Trump has named Tesla CEO Elon Musk and former Republican presidential candidate Vivek Ramaswamy to lead the newly formed Department of Government Efficiency (D.O.G.E). The initiative aims to streamline government operations and cut wasteful government spending.  Trump Appoints Elon Musk And Vivek Ramaswamy To Head D.O.G.E And Cut $2 Trillion In Government [...]

Collision avoidance technologies need beefing up to cope with solar storms, says astronomers.

A new brightness forecast for Comet Tsuchinshan-ATLAS whets our hopes for a fine appearance in late September and early October.

The post Update: Comet Tsuchinshan-ATLAS Might Outshine Predictions appeared first on Sky & Telescope.

Location: Electronic Resource- 

(The Center Square) – What is in store for the Illinois housing market in 2024 is uncertain, but inventories and interest rates are expected to be a major factor.

In this episode, Thomas Domville demonstrates how to enable or disable predictive text and inline predictive text on iOS. Predictive text allows you to write entire sentences with just a few taps. As you type, suggested words, emoji, and information appear above the onscreen keyboard. You can double tap a suggestion to apply it. Inline predictions complete the word or phrase you’re currently typing, appearing in gray text. To accept an inline prediction, double tap the Space bar; to reject it, keep typing. You can manage predictive text settings in Keyboard settings on your iPhone 12 or newer models running iOS 17 or later versions.

Open Settings on your iPhone.
Scroll down and double tap on General.
Double tap Keyboard.
Double tap the Predictive switch to enable or disable predictive text.
To manage inline predictive text, ensure that the Predictive switch is enabled or disabled.
While typing, you’ll see inline predictions. To accept a suggestion, double tap the Space bar; to reject it, keep typing.

transcription:
Disclaimer: This transcript is generated by AIKO, an automated transcription service. It is not edited or formatted, and it may not accurately capture the speakers’ names, voices, or content.

Hello and welcome.

My name is Thomas Donville also known as AnonyMouse.

Now every so often when I am composing an email or I'm trying to send off a text to a friend or family whatever that might be and I'm using the keyboard as I'm typing there is something called predictive text that will pop up so it tries to predict what you are going to spell out and this feature what this does it tries to help you shorten your typing that you have to do so you just find the various words on top of your keyboard tap on that and it selects that then they have this inline predictive text now which is a newer feature which takes it a next step that allows you to highlight within the text itself and allows you to choose those words but for me those are distracting I am trying to focus and I am NOT a multitasker as I would love to be but as I'm typing along I it just bothers me hearing these words pop up and they don't help me at all I want to kind of stay focused and type in what I want so I'm going to show you how you can turn those features off if you are interested in doing so and if you are distracted like I am when those things come up I'm also going to show you some pointers and advice some other things you can turn off as well what they call features and for some may be distracting to you as well or something that drives you bonkers so do in order to go and change this settings we are going to head over to the native settings itself settings double tap to open now that you located the settings let's do one finger double tap to open this up settings now you are going to need to swipe to the right until we get to something called general general button and we are going to do one finger double tap here about button and now we are looking for something called keyboard so swipe to the right until you get to keyboard keyboard button and at last we are here one finger double tap on keyboard keyboards to button now the easiest way to get to the area that we need to do is set your rotor to headings and go to the first heading all keyboards heading and now what we're looking for is predictive text so swipe to the right a couple times and…

In this episode, Tyler demonstrates how to disable predictive text suggestions on macOS.

As you type on your Mac, macOS by default attempts to finish words and phrases it thinks you're trying to type. If you find that hearing these suggestions spoken by VoiceOver is more distracting than helpful, you can turn them off by going to System Settings > Keyboard, clicking the Edit button under the "Text input" heading, and toggling the "show inline predictive text" switch off.

transcription:

Disclaimer: This transcript is generated by AIKO, an automated transcription service. It is not edited or formatted, and it may not accurately capture the speakers’ names, voices, or content.

Hey, Apple vissers, Tyler here, with a quick tip for how to disable predictive text suggestions on macOS.

By default, as you type on your Mac, macOS attempts to finish words and phrases that it thinks you're trying to type.

While this may increase the speed of text entry for some, if you're a voiceover user, you may find that hearing these suggestions spoken while you're trying to type is more distracting than helpful, in which case you can turn them off.

To do that, go into system settings, keyboard, hit the edit button under the text input heading, and turn the show inline predictive text switch off.

And I'm going to demonstrate that now, I'm going to system settings on my Mac, k for keyboard, vio command h to get to the text input heading, vio right, edit, and at the leftmost of this dialog, k, that's what we want, vio right, scroll area, interact with vio shift down arrow, and vio right until I find the setting I want, show inline predictive text, if I vio right once more, show inline predictive text off switch, it's off for me because I turned it off.

If it's on for you and you want to turn it off, just press vio space, then stop interacting with the scroll area, with vio shift up arrow, and vio right to done, hit it, and here we are back in keyboard settings.

So now as you type, you will not hear text suggestions predicted by macOS, which could almost ironically increase your speed of text entry because this feature is off and is no longer giving you distracting or potentially distracting feedback.

So that's a tip for how to disable predictive text suggestions on macOS, I hope you found it helpful.

Peace.

Thank you.

President-elect Donald Trump has gone against media expectations by tapping Marco Rubio, Kristi Noem and a number of other Capitol Hill veterans to fill posts in his second administration.

NPR's Scott Simon speaks to Sunmin Kim, an assistant professor in Dartmouth College's sociology department, about the reliability of political polling leading up to elections.

BETTING agency Sportsbet has predicted Macarthur to be the only western Sydney seat expected to change hands after Saturday’s Federal Election.

Over the past two decades, Google has hosted two different internal platforms for predictions. Why did the first one fail — and will the other endure?

On any given night, Nuggets center Nikola Jokic or Avalanche center Nathan MacKinnon can be a whole flight of stairs above any competitor on the court or in the rink.

Bermuda triple jumper Jah-Nhai Perinchief was always confident he would one day represent the island at the Olympic Games. Perinchief, who is making his Olympic debut in Paris, gets his campaign underway today [August 7] in the men’s triple jump qualifiers at the Stade de France. In a YouTube video from the Youth Olympic Games […]

1. New Model Predicts Intelligent Life Odds in Universe  Mirage News
2. Formula for alien life: Drake Equation gets a dark energy update  Cosmos

1. Right now, the Sun is far more active than predicted – and small satellites are paying the price  The Conversation
2. Unpredictable Solar Activity Sends Satellites Plummeting to Earth  ScienceAlert

Despicable Me 4 tie-in smells more like popcorn while a waddling duck and an interactive pet monkey also feature A “fart blaster” with a repertoire of 15 sounds that blasts “fog fart rings” and a waddling mother duck are among the toys destined to appear on Christmas lists as experts predict a…

The dust is settling on this year’s Premier League season, and Blues fans are both satisfied and, have a right..

The post Early Prediction: Chelsea’s Chances in the 2024/25 Premier League appeared first on Chelsea FC Blog.

Two hours before asteroid 2022 EB5 entered Earth’s atmosphere, scientists knew exactly when and where the space rock would strike.

Texts classified according to guided reading levels (GRL) are ubiquitous in U.S. beginning reading classrooms. This study examined features of texts across three grade bands (kindergarten, early first grade, final first grade) and the 10 GRLs within these bands. The 510 texts came from three programs with different functions in beginning reading instruction: core, intervention, and content areas.

Continuing to set records, Pepe Unchained recently achieved a new milestone after reaching $26 million. The project’s presale has now… Continue reading As Pepe Unchained Launch Date Nears, Analyst Makes ‘Massive’ Prediction For PEPU

The post As Pepe Unchained Launch Date Nears, Analyst Makes ‘Massive’ Prediction For PEPU appeared first on ReadWrite.

The country is set to experience varied weather conditions, with several impact-based warnings issued across various provinces, according to the South African Weather Service.

China Needs to Make the Belt and Road Initiative More Transparent and Predictable Expert comment sysadmin 29 April 2019

The global infrastructure project must move beyond mish-mash of opaque bilateral deals

As China welcomes dozens of world leaders to Beijing for its second Belt and Road forum, it has one simple aim: relaunching President Xi Jinping’s controversial global infrastructure drive.

Since it began five years ago, the Belt and Road Initiative (BRI) has sunk hundreds of billions into port, railway and power projects stretching from south-east Asia to central Europe. But its path has been bumpy, drawing sharp criticism over the ruinous debts that some countries have racked up amid Chinese largesse.

Xi will stress sustainable financing and transparency this week, amid the usual talk of ‘win win’ cooperation. Yet BRI’s problems are structural, not presentational. For any pledges to be meaningful, China must move beyond its present mish-mash of opaque, bilateral deals.

After bad headlines last year, BRI has in fact enjoyed a good run in recent weeks. Malaysia announced it would resume a previously cancelled high-speed rail project, while Italy’s decision to join up last month marked a further European incursion. Indeed, if attendance is any guide to success, BRI looks in fine fettle. The first forum in 2017 attracted 29 world leaders. China says 37 will turn up this week. Phillip Hammond, UK chancellor, arrives hunting deals too, just a day after news that Chinese technology group Huawei will be allowed to help build 5G networks in Britain.

Even so, three interlinked problems remain at the heart of President Xi’s pet project, all of which must be addressed if BRI is to move beyond the pitfalls that have damaged its reputation.

The first and most obvious is debt. Critics allege that China ‘traps’ its BRI partners financially, often pointing to a debt-for-equity deal that handed China control of a port in Sri Lanka. These claims are exaggerated — few other projects have ended up this way. Yet poorer nations from Laos to Tajikistan are still signing up to vastly expensive Chinese schemes that offer poor value for money while straining their public finances.

The second problem is transparency. Despite its grand scale there is still no reliable list of BRI projects, no disclosure of the lending standards China follows, nor even the amount China has invested. Beijing claims more than $1 trillion; independent estimates suggest perhaps a few hundred billion. Either way, it will be hard for China to convince doubters on debts until it is open about the criteria it uses in deciding who to lend to and why.

BRI’s third and most important challenge is its muddled organization. Despite BRI’s image as a centrally run mega-project, China has allowed many deals to be struck locally, via a mix of state-backed companies, public sector banks and freewheeling regional governments. And it is here that the problems began.

Infrastructure deals are notoriously complex, especially for transnational projects like high-speed rail. Renegotiations are common, even for experienced bodies like the World Bank. Yet BRI has repeatedly seen terms negotiated behind closed doors, in countries such as Malaysia and Pakistan, come unstuck in the face of public outcry.

Rather than seeking to trap others with debt, China’s central government more often has to step in to fix dubious projects agreed by underlings lower down the chain.

These negotiations go one of two ways. Either China’s partners complain and win terms, as was true in Malaysia and in Myanmar over a multibillion-dollar deep-sea port. Or, as in the case of Sri Lanka, the renegotiations go in China’s favour, but at the cost of accusations of debt trickery. In both cases China looks bad.

Speaking last year, Xi responded to criticism of BRI by describing it as ‘an open platform for cooperation’. Yet, so far, he has proved resistant to the step that would deliver on that vision — namely turning BRI into an institution with open standards and international partners.

The reasons for his reluctance are obvious. Ending BRI’s reliance on loose bilateral deals would limit Beijing’s room for geopolitical manoeuvre. Yet what might be lost in political flexibility could easily be gained in economic credibility, while avoiding some of the painful renegotiations that have dogged many BRI projects.

At a time when China’s economy is slowing and its current account surplus is shrinking, formalising and institutionalising, BRI could also help avoid wasting scarce public resources on white elephant projects. China even has an easy template in the form of the Asian Infrastructure Investment Bank, the Beijing-based institution that has won plaudits for its project quality and openness since it started in 2016.

Whichever model is chosen, a dose of Chinese-style central planning is called for, along with more openness. Without it, the oddly chaotic and decentralised model pioneered in BRI’s first five years is unlikely to help the project thrive over the next five.

This article was originally published in the Financial Times.

Yu Xue
Sep 1, 2008; 7:1598-1608
Research

Visual Abstract

Visual Abstract

Kailun Fang
Nov 30, 2020; 0:RA120.002081v1-mcp.RA120.002081
Research

Leandro Xavier Neves
Nov 11, 2020; 0:RA120.002227v1-mcp.RA120.002227
Research

Protease activity has been associated with pathological processes that can lead to cancer development and progression. However, understanding the pathological unbalance in proteolysis is challenging since changes can occur simultaneously at protease, their inhibitor and substrate levels. Here, we present a pipeline that combines peptidomics, proteomics and peptidase predictions for studying proteolytic events in the saliva of seventy-nine patients and their association with oral squamous cell carcinoma (OSCC) prognosis. Our findings revealed differences in the saliva peptidome of patients with (pN+) or without (pN0) lymph node metastasis and delivered a panel of ten endogenous peptides correlated with poor prognostic factors plus five molecules able to classify pN0 and pN+ patients (ROC-AUC>0.85). In addition, endo- and exopeptidases putatively implicated in the processing of differential peptides were investigated using cancer tissue gene expression data from publicly repositories reinforcing their association with poorer survival rates and prognosis in oral cancer. The dynamics of the OSCC-related proteolysis was further explored via the proteomic profiling of saliva. This revealed that peptidase/endopeptidase inhibitors exhibited reduced levels in the saliva of pN+ patients, as confirmed by SRM-MS, whilst minor changes were detected in the level of saliva proteases. Taken together, our results indicated that proteolytic activity is accentuated in the saliva of OSCC patients with lymph node metastasis and, at least in part, this is modulated by reduced levels of salivary peptidase inhibitors. Therefore, this integrated pipeline provided better comprehension and discovery of molecular features with implications in the oral cancer metastasis prognosis.

The molecular mechanism associated with mammalian meiosis has yet to be fully explored, and one of the main reasons for this lack of exploration is that some meiosis-essential genes are still unknown. The profiling of gene expression during spermatogenesis has been performed in previous studies, yet few studies have aimed to find new functional genes. Since there is a huge gap between the number of genes that are able to be quantified and the number of genes that can be characterized by phenotype screening in one assay, an efficient method to rank quantified genes according to phenotypic relevance is of great importance. We proposed to rank genes by the probability of their function in mammalian meiosis based on global protein abundance using machine learning. Here, nine types of germ cells focusing on continual substages of meiosis prophase I were isolated, and the corresponding proteomes were quantified by high-resolution mass spectrometry. By combining meiotic labels annotated from the MGI mouse knockout database and the spermatogenesis proteomics dataset, a supervised machine learning package, FuncProFinder, was developed to rank meiosis-essential candidates. Of the candidates whose functions were unannotated, four of ten genes with the top prediction scores, Zcwpw1, Tesmin, 1700102P08Rik and Kctd19, were validated as meiosis-essential genes by knockout mouse models. Therefore,  mammalian meiosis-essential genes could be efficiently predicted based on the protein abundance dataset, which provides a paradigm for other functional gene mining from a related abundance dataset.

Artificial Intelligence Prediction and Counterterrorism Research paper sysadmin 6 August 2019

The use of AI in counterterrorism is not inherently wrong, and this paper suggests some necessary conditions for legitimate use of AI as part of a predictive approach to counterterrorism on the part of liberal democratic states.

Summary

• The use of predictive artificial intelligence (AI) in countering terrorism is often assumed to have a deleterious effect on human rights, generating spectres of ‘pre-crime’ punishment and surveillance states. However, the well-regulated use of new capabilities may enhance states’ abilities to protect citizens’ right to life, while at the same time improving adherence to principles intended to protect other human rights, such as transparency, proportionality and freedom from unfair discrimination. The same regulatory framework could also contribute to safeguarding against broader misuse of related technologies.
• Most states focus on preventing terrorist attacks, rather than reacting to them. As such, prediction is already central to effective counterterrorism. AI allows higher volumes of data to be analysed, and may perceive patterns in those data that would, for reasons of both volume and dimensionality, otherwise be beyond the capacity of human interpretation. The impact of this is that traditional methods of investigation that work outwards from known suspects may be supplemented by methods that analyse the activity of a broad section of an entire population to identify previously unknown threats.
• Developments in AI have amplified the ability to conduct surveillance without being constrained by resources. Facial recognition technology, for instance, may enable the complete automation of surveillance using CCTV in public places in the near future.
• The current way predictive AI capabilities are used presents a number of interrelated problems from both a human rights and a practical perspective. Where limitations and regulations do exist, they may have the effect of curtailing the utility of approaches that apply AI, while not necessarily safeguarding human rights to an adequate extent.
• The infringement of privacy associated with the automated analysis of certain types of public data is not wrong in principle, but the analysis must be conducted within a robust legal and policy framework that places sensible limitations on interventions based on its results.
• In future, broader access to less intrusive aspects of public data, direct regulation of how those data are used – including oversight of activities by private-sector actors – and the imposition of technical as well as regulatory safeguards may improve both operational performance and compliance with human rights legislation. It is important that any such measures proceed in a manner that is sensitive to the impact on other rights such as freedom of expression, and freedom of association and assembly.

Phillies pitchers and catchers have their first workout Wednesday morning at Carpenter Complex. Almost anything can happen between Wednesday and Opening Day. That said, here is a very early prediction of the Phillies' Opening Day roster, knowing the Phillies remain in the hunt to sign Bryce Harper or Manny Machado.

The Angels head to Spring Training with most of their roster set, but there will be competition for a few spots. Here's a look at the projected roster for the Angels, as they begin their first campaign under manager Brad Ausmus.

Our objective is to explore quantitative imaging markers for early prediction of treatment response in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs) undergoing [¹⁷⁷Lu]Lu-DOTATATE therapy. By doing so, we aim to enable timely switching to more effective therapies in order to prevent time-resource waste and minimize toxicities. Methods: Patients diagnosed with unresectable or metastatic, progressive, well-differentiated, receptor-positive GEP-NETs who received 4 sessions of [¹⁷⁷Lu]Lu-DOTATATE were retrospectively selected. Using SPECT/CT images taken at the end of treatment sessions, we counted all visible tumors and measured their largest diameters to calculate the tumor burden score (TBS). Up to 4 target lesions were selected and semiautomatically segmented. Target lesion peak counts and spleen peak counts were measured, and normalized peak counts were calculated. Changes in TBS (TBS) and changes in normalized peak count (nPC) throughout treatment sessions in relation to the first treatment session were calculated. Treatment responses were evaluated using third-month CT and were binarized as progressive disease (PD) or non-PD. Results: Twenty-seven patients were included (7 PD, 20 non-PD). Significant differences were observed in TBS_second-first, TBS_third-first, and TBS_fourth-first (where second-first, third-first, and fourth-first denote scan number between the second and first, third and first, and fourth and first [¹⁷⁷Lu]Lu-DOTATATE treatment cycles), respectively) between the PD and non-PD groups (median, 0.043 vs. –0.049, 0.08 vs. –0.116, and 0.109 vs. –0.123 [P = 0.023, P = 0.002, and P < 0.001], respectively). nPC_second-first showed significant group differences (mean, –0.107 vs. –0.282; P = 0.033); nPC_third-first and nPC_fourth-first did not reach statistical significance (mean, –0.122 vs. –0.312 and –0.183 vs. –0.405 [P = 0.117 and 0.067], respectively). At the optimal threshold, TBS_fourth-first exhibited an area under the curve (AUC) of 0.957, achieving 100% sensitivity and 80% specificity. TBS_second-first and TBS_third-first reached AUCs of 0.793 and 0.893, sensitivities of 71.4%, and specificities of 85% and 95%, respectively. nPC_second-first, nPC_third-first, and nPC_fourth-first showed AUCs of 0.764, 0.693, and 0.679; sensitivities of 71.4%, 71.4%, and 100%; and specificities of 75%, 70%, and 35%, respectively. Conclusion: TBS and nPC can predict [¹⁷⁷Lu]Lu-DOTATATE response by the second treatment session.

Unspecific bone uptake (UBU) related to [¹⁸F]PSMA-1007 PET/CT imaging represents a clinical challenge. We aimed to assess whether a combination of clinical, biochemical, and imaging parameters could predict skeletal metastases in patients with [¹⁸F]PSMA-1007 bone focal uptake, aiding in result interpretation. Methods: We retrospectively analyzed [¹⁸F]PSMA-1007 PET/CT performed in hormone-sensitive prostate cancer (PCa) patients at 3 tertiary-level cancer centers. A fourth center was involved in performing an external validation. For each, a volume of interest was drawn using a threshold method to extract SUV_max, SUV_mean, PSMA tumor volume, and total lesion PSMA. The same volume of interest was applied to CT images to calculate the mean Hounsfield units (HU_mean) and maximum Hounsfield units. Clinical and laboratory data were collected from electronic medical records. A composite reference standard, including follow-up histopathology, biochemistry, and imaging data, was used to distinguish between PCa bone metastases and UBU. PET readers with less (n = 2) or more (n = 2) experience, masked to the reference standard, were asked to visually rate a subset of focal bone uptake (n = 178) as PCa metastases or not. Results: In total, 448 bone [¹⁸F]PSMA-1007 focal uptake specimens were identified in 267 PCa patients. Of the 448 uptake samples, 188 (41.9%) corresponded to PCa metastases. Ongoing androgen deprivation therapy at PET/CT (P < 0.001) with determination of SUV_max (P < 0.001) and HU_mean (P < 0.001) independently predicted bone metastases. A composite prediction score, the bone uptake metastatic probability (BUMP) score, achieving an area under the receiver-operating-characteristic curve (AUC) of 0.87, was validated through a 10-fold internal and external validation (n = 89 bone uptake, 51% metastatic; AUC, 0.92). The BUMP score’s AUC was significantly higher than that of HU_mean (AUC, 0.62) and remained high among lesions with HU_mean in the first tertile (AUC, 0.80). A decision-curve analysis showed a higher net benefit with the score. Compared with the visual assessment, the BUMP score provided added value in terms of specificity in less-experienced PET readers (88% vs. 54%, P < 0.001). Conclusion: The BUMP score accurately distinguished UBU from bone metastases in PCa patients with [¹⁸F]PSMA-1007 focal bone uptake at PET imaging, offering additional value compared with the simple assessment of the osteoblastic CT correlate. Its use could help clinicians interpret imaging results, particularly those with less experience, potentially reducing the risk of patient overstaging.

Neoadjuvant therapy in patients with locally advanced rectal cancer (LARC) has achieved good pathologic complete response (pCR) rates, potentially eliminating the need for surgical intervention. This study investigated preoperative methods for predicting pCR after neoadjuvant short-course radiotherapy (SCRT) combined with immunochemotherapy. Methods: Treatment-naïve patients with histologically confirmed LARC were enrolled from February 2023 to July 2023. Before surgery, the patients received neoadjuvant SCRT followed by 2 cycles of capecitabine and oxaliplatin plus camrelizumab. ⁶⁸Ga-labeled fibroblast activation protein inhibitor ([⁶⁸Ga]Ga-FAPI-04) PET/MRI, [¹⁸F]FDG PET/CT, and contrast-enhanced MRI were performed before treatment initiation and before surgery in each patient. PET and MRI features and the size and number of lesions were also collected from each scan. Each parameter’s sensitivity, specificity, and diagnostic cutoff were derived via receiver-operating-characteristic curve analysis. Results: Twenty eligible patients (13 men, 7 women; mean age, 60.2 y) were enrolled and completed the entire trial, and all patients had proficient mismatch repair or microsatellite-stable LARC. A postoperative pCR was achieved in 9 patients (45.0%). In the visual evaluation, both [⁶⁸Ga]Ga-FAPI-04 PET/MRI and [¹⁸F]FDG PET/CT were limited to forecasting pCR. Contrast-enhanced MRI had a low sensitivity of 55.56% to predict pCR. In the quantitative evaluation, [⁶⁸Ga]Ga-FAPI-04 change in SUL_peak percentage, where SUL_peak is SUV_peak standardized by lean body mass, had the largest area under the curve (0.929) with high specificity (sensitivity, 77.78%; specificity, 100.0%; cutoff, 63.92%). Conclusion: [⁶⁸Ga]Ga-FAPI-04 PET/MRI is a promising imaging modality for predicting pCR after SCRT combined with immunochemotherapy. The SUL_peak decrease exceeding 63.92% may provide valuable guidance in selecting patients who can forgo surgery after neoadjuvant therapy.

Nov. 8, 2024 — Barcelona Supercomputing Center‘s Innostroke project aims to transform the prevention and monitoring of stroke, one of the leading causes of death and disability worldwide, through artificial […]

The post BSC Develops AI Model to Predict Stroke Risk Using Mobile Devices appeared first on HPCwire.

SURREY, British Columbia, Nov. 12, 2024 — Today, the Quantum Algorithms Institute (QAI) announced a partnership with Canadian companies, AbaQus and InvestDEFY Technologies, to solve common challenges in training machine learning […]

The post Quantum Algorithms Institute Drives Predictive Model Accuracy with Quantum Collaboration appeared first on HPCwire.

A hole in the atmosphere's ozone layer is the seventh-smallest since recovery began in 1992, the National Oceanic and Atmospheric Administration announced Wednesday.

Research from REL Midwest examines the student characteristics associated with early college success in Indiana, with a focus on financial aid.

On Wednesday at Moody Center, a Lamar team that went 24-7 last season should provide a tougher test for the Longhorns than in their season opener.

Michele Deodato
Oct 2, 2024; 44:e2308232024-e2308232024
BehavioralSystemsCognitive

Kyle E. Mathewson
Mar 4, 2009; 29:2725-2732
BehavioralSystemsCognitive

Sleep is known to drive the consolidation of motor memories. During nonrapid eye movement (NREM) sleep, the close temporal proximity between slow oscillations (SOs) and spindles ("nesting" of SO-spindles) is known to be essential for consolidation, likely because it is closely associated with the reactivation of awake task activity. Interestingly, recent work has found that spindles can occur in temporal clusters or "trains." However, it remains unclear how spindle trains are related to the nesting phenomenon. Here, we hypothesized that spindle trains are more likely when SOs co-occur in the prefrontal and motor cortex. We conducted simultaneous neural recordings in the medial prefrontal cortex (mPFC) and primary motor cortex (M1) of male rats training on the reach-to-grasp motor task. We found that intracortically recorded M1 spindles are organized into distinct temporal clusters. Notably, the occurrence of temporally precise SOs between mPFC and M1 was a strong predictor of spindle trains. Moreover, reactivation of awake task patterns is much more persistent during spindle trains in comparison with that during isolated spindles. Together, our work suggests that the precise coupling of SOs across mPFC and M1 may be a potential driver of spindle trains and persistent reactivation of motor memory during NREM sleep.

Looking at the future of geopolitics, the author reveals the surprising results of his research. Read more at http://www.smithsonianmag.com/specialsections/40th-anniversary/George-Friedman-on-World-War-III.html

A learning simulation, combined with fMRI readings, is able to predict the visualizations seen by a dreamer in real time

Our host, Eric Schulze, explains how science is tackling this puzzling question from space.

The pivot from Apple Car set the stage for bigger investments in the smart home, and the initial products from that shift could be launching as soon as March according to a new rumor.