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Smithsonian anthropologist Rick Potts answers questions about the Anthropocene

There is little doubt that human activity is affecting planet Earth, but just how much? And is it all negative? Rick Potts is the director […]

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Prehistoric mouthparts

These striking images of six insect heads and mouthparts were drawn from fossils by Conrad Labandeira, Curator of Fossil Arthropods (insects and related animals) at […]

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First wild horse species born from artificial insemination at Smithsonian Conservation Biology Institute

Scientists at the Smithsonian Conservation Biology Institute are celebrating the birth of a female Przewalski’s (Cha-VAL-skee) horse—the first to be born via artificial insemination. The […]

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Smithsonian secretary on the future of museums, libraries and archives

To download the free e-book Best of Both Worlds: Museums, Libraries, and Archives in a Digital Age, by G. Wayne Clough, Secretary of the Smithsonian, […]

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Newfound planet is Earth-mass but gassy

An international team of astronomers has discovered the first Earth-mass planet that transits, or crosses in front of, its host star. KOI-314c is the lightest […]

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Smithsonian scientist confirms missing link in big cat evolution

After years of sleuthing for clues about where and when pantherine felids (“big cats”) originated, a Smithsonian scientist and an international team of researchers are […]

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Micronesian kingfisher chick hatches at the National Zoo’s Conservation Biology Institute

The Smithsonian Conservation Biology Institute rung in 2014 with the hatching of the most endangered species in its collection—a Micronesian kingfisher—Jan. 1. The chick, whose […]

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Star cluster thrown out of its galaxy

The galaxy known as M87 has a fastball that would be the envy of any baseball pitcher. It has thrown an entire star cluster toward […]

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With too few males, blue crab population may be put at risk

The practice of selectively fishing male blue crabs in the Chesapeake—intended to give females a chance to reproduce—may have a hidden cost. A Bay without […]

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Finding ET by searching for alien air pollution

Humanity is on the threshold of being able to detect signs of alien life on other worlds. By studying exoplanet atmospheres, we can look for […]

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Biological fallout of shale-gas production still largely unknown

In the United States, natural-gas production from shale rock has increased by more than 700 percent since 2007. Yet scientists still do not fully understand […]

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Nautilus shell deformity puzzles scientists

In the wild, wide milk chocolate-brown stripes adorn the beautiful smooth, white shells of the chambered nautilus, a deep-diving mollusk from the Indo-Pacific Ocean. But […]

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International team maps ‘big bang’ of bird evolution

The genomes of modern birds tell a story of how they emerged and evolved after the mass extinction that wiped out dinosaurs 66 million years […]

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Swarms of Pluto-size objects kick up dust around adolescent star

Astronomers using the Atacama Large Millimeter/submillimeter Array (ALMA) may have detected the dusty hallmarks of an entire family of Pluto-size objects swarming around an adolescent […]

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Desire for Pacific bluefin puts fish on red list of threatened species

Eaten raw and thinly sliced, the dark-red belly meat of the Pacific bluefin tuna is highly prized—and priced—for its rich oily flavor by sashimi and […]

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Corn entered Southwest U.S. first along highland route, DNA shows

A new DNA study of ancient corn kernels and cobs from archaeological sites across North America has settled a long debate as to exactly where […]

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6 Things You Probably Didn’t Know About Andean Bears

Giant pandas. Grizzlies. Polar bears. You’ve probably heard a lot about these bear species, but what about Andean bears? To the Quechua and Aymara, the […]

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Key Link in Turtle Evolution discovered

An international team of researchers from the United States and Germany have discovered a key missing link in the evolutionary history of turtles. The new […]

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Study reveals more Pygmy Sloths, But There Still Aren’t Many

Size isn’t the only thing that’s small about the pygmy sloth―its population is too. But scientists at the Smithsonian say things may be looking up […]

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Parasitic flatworms flout global biodiversity patterns

The odds of being attacked and castrated by a variety of parasitic flatworms increases for marine horn snails the farther they are found from the […]

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Remarkable butterfly look-alike lived 50 million years before butterflies appeared

New fossils found in Northeastern China have revealed a remarkable evolutionary coincidence: an extinct group of insects known as Kalligrammatid lacewings (Order Neuroptera) share an […]

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Ghost octopod shows how little we know about deep-sea life

A social media celebrity was born last week when the bright lights and camera of NOAA’s remotely operated vehicle Deep Discoverer zoomed in on a […]

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Sacred shrew mummies reveal species distribution in ancient Egypt

Nocturnal, solitary and fiercely territorial the adult Egyptian pigmy shrew—one of the smallest mammals on earth—weighs just 7 grams. French zoologist Isidore Geoffroy Saint-Hilaire first […]

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Smithsonian Expert Urges Caution, Patience on Blue Crab Recovery

The results are in, 2016 is going to be a good year for blue crabs in the Chesapeake Bay. An iconic figure embedded in the […]

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Five things only a conservator would know about the USS Enterprise

Space: the final frontier. These are the voyages of the Starship Enterprise…and you know the rest, probably even if you’re not a huge fan of […]

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The Milky Way’s blowout bash 6 million years ago!

The center of the Milky Way galaxy is currently a quiet place where a supermassive black hole slumbers, only occasionally slurping small sips of hydrogen […]

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Climate Change May Benefit Native Oysters, but There’s a Catch

Amid efforts to restore native oyster populations on the West Coast, how are oysters expected to fare under climate change in the decades and centuries […]

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Whale tagging in Southeast Pacific provides data for species protection

Whales from both poles migrate long distances to breed in tropical waters. Smithsonian scientist Hector M. Guzman and Fernando Félix at the Salinas Whale Museum […]

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New technique may help authorities quickly ID real and fake ivory products

Fetching close to $1,500 per pound, ivory ranks fourth in black-market traded items just behind illegal drugs, weapons, and humans. Governments across the globe are […]

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  • Animals
  • Art
  • History & Culture
  • Research News
  • Science & Nature
  • Smithsonian Conservation Biology Institute
  • Smithsonian's National Zoo

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Surprise: Distinctive new surgeonfish species makes an improbable debut

Sometimes there’s just no telling what will turn up at the local market. Fish biologist Jeff Williams of the Smithsonian’s National Museum of Natural History […]

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A new stellar X-ray “reality” show debuts

A new project using data from NASA’s Chandra X-ray Observatory and other telescopes allows people to navigate through real data of the remains of an […]

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  • Science & Nature
  • Space
  • Center for Astrophysics | Harvard & Smithsonian
  • Chandra X-Ray Observatory

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Underpaid women “computers” mapped the universe in the 19th century

Every day, astronomers at the Harvard-Smithsonian Center for Astrophysics depend on computers to help them solve the mysteries of the universe, just as they did […]

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  • Science & Nature
  • Space
  • astrophysics
  • Center for Astrophysics | Harvard & Smithsonian

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Study of bacteria inside guts of wild Canada geese shows greater danger than earlier studies exposed

In the early 20th century, Canada geese were considered endangered in the U.S. So in the 1950s and 1960s, birds from the Midwest were released […]

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A solar probe is on its way to touch the sun. The Smithsonian built the tool that will measure the sun without melting

Smithsonian scientists have joined NASA and other organizations this summer to do something incredible: launch a spacecraft, the Parker Solar Probe, into space and have […]

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  • Science & Nature
  • Space
  • Smithsonian Astrophysical Observatory

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Windows server 2012 r2 cant access imap server in outlook




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Windows Server 2016: Audio In/Out through Remote Desktop to Thinclients




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Windows Server 2019, autounattend install fails, No images are available..




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Windows Server 2012 outgrows C: partition




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Use GPO to Import Safe Senders & Auto Download External Email Content




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WinRM authentication error




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Crystal and solution structures of fragments of the human leucocyte common antigen-related protein

Leucocyte common antigen-related protein (LAR) is a post-synaptic type I transmembrane receptor protein that is important for neuronal functionality and is genetically coupled to neuronal disorders such as attention deficit hyperactivity disorder (ADHD). To understand the molecular function of LAR, structural and biochemical studies of protein fragments derived from the ectodomain of human LAR have been performed. The crystal structure of a fragment encompassing the first four FNIII domains (LARFN1–4) showed a characteristic L shape. SAXS data suggested limited flexibility within LARFN1–4, while rigid-body refinement of the SAXS data using the X-ray-derived atomic model showed a smaller angle between the domains defining the L shape compared with the crystal structure. The capabilities of the individual LAR fragments to interact with heparin was examined using microscale thermophoresis and heparin-affinity chromatography. The results showed that the three N-terminal immunoglobulin domains (LARIg1–3) and the four C-terminal FNIII domains (LARFN5–8) both bound heparin, while LARFN1–4 did not. The low-molecular-weight heparin drug Innohep induced a shift in hydrodynamic volume as assessed by size-exclusion chromatography of LARIg1–3 and LARFN5–8, while the chemically defined pentameric heparin drug Arixtra did not. Together, the presented results suggest the presence of an additional heparin-binding site in human LAR.




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“Falling to Earth: An Apollo 15 Astronaut’s Journey to the Moon” by Al Worden with Francis French

As command module pilot for the Apollo 15 mission to the moon in 1971, Al Worden spent six days orbiting the moon, including three days completely alone, the most isolated human in existence. In Falling to Earth, Worden tells for the first time the full story around the dramatic events that shook NASA and ended his spaceflight career.

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