Two Cuban crocodiles were born at the Smithsonian’s National Zoo on July 6 and 14 and they are among the most genetically valuable in the […]

The post Two rare Cuban crocodiles born at the National Zoo appeared first on Smithsonian Insider.

The discovery of the first transiting circumbinary multi-planet system: two planets orbiting around a pair of stars, is announced by astronomers.

The post Planetary system orbiting two suns discovered by astronomers appeared first on Smithsonian Insider.

Two Andean bear cubs born at the National Zoo in the early morning of Dec. 13 to 6-year-old Billie Jean.

The post Two Andean bear cubs born Dec. 13 at National Zoo appeared first on Smithsonian Insider.

In our solar system, only one planet is blessed with an ocean: Earth. Our home world is a rare, blue jewel compared to the deserts […]

The post Astronomers discover two water worlds orbiting star Kepler-62 appeared first on Smithsonian Insider.

Emmett Duffy, currently the Gluckman Professor of Marine Science at the College of William & Mary in Virginia, has been appointed director of the Smithsonian’s […]

The post Emmett Duffy named director of Smithsonian’s Tennenbaum Marine Observatories Network appeared first on Smithsonian Insider.

A newly released study focusing on an extinct species, the Caribbean monk seal (Monachus tropicalis), has revealed just how evolutionarily unique its only two living […]

The post Too valuable to lose: Extinct relative reveals rarity of last two remaining monk seal species appeared first on Smithsonian Insider.

Two worlds orbiting a distant star are about to become a snack of cosmic proportions. Astronomers have announced that the planets Kepler-56b and Kepler-56c will […]

The post Star set to swallow two planets appeared first on Smithsonian Insider.

The odds of being attacked and castrated by a variety of parasitic flatworms increases for marine horn snails the farther they are found from the […]

The post Parasitic flatworms flout global biodiversity patterns appeared first on Smithsonian Insider.

Fat, toxic and nocturnal, cane toads (Rhinella marina) are abundant today in Hawaii, even though they are South American natives. Released on the Hawaiian Islands […]

The post Two invasive species have Hawaiian reunion after 80-year separation appeared first on Smithsonian Insider.

Chances are, if you’ve been stung by a jellyfish along the Chesapeake Bay it was by a sea nettle jellyfish–one of the most common and […]

The post Scientists discover common sea nettle jellyfish is actually two distinct species appeared first on Smithsonian Insider.

Flitting swiftly through the darkness above the tropical forest canopy in Central and South America, a group of cute little bats with dog-like faces have […]

The post More sky puppies! Scientists discover two new species of dog-faced bat appeared first on Smithsonian Insider.

Archan Chakraborty, Wei-Cheng Lin, Yu-Tsun Lin, Kuang-Jing Huang, Pei-Yu Wang, Yi-Feng Chang, Hsiang-Iu Wang, Kung-Ting Ma, Chun-Yen Wang, Xuan-Rong Huang, Yen-Hsien Lee, Bi-Chang Chen, Ya-Ju Hsieh, Kun-Yi Chien, Tzu-Yang Lin, Ji-Long Liu, Li-Ying Sung, Jau-Song Yu, Yu-Sun Chang, and Li-Mei Pai

Under metabolic stress, cellular components can assemble into distinct membraneless organelles for adaptation. One such example is cytidine 5'-triphosphate synthase (CTPS), which forms filamentous structures under glutamine deprivation. We have previously demonstrated that histidine (His)-mediated methylation regulates the formation of CTPS filaments to suppress enzymatic activity and preserve the CTPS protein under Gln deprivation, which promotes cancer cell growth after stress alleviation. However, it remains unclear where and how these enigmatic structures are assembled. Using CTPS-APEX2-mediated in vivo proximity labeling, we found that SNAP29 regulates the spatiotemporal filament assembly of CTPS along the cytokeratin network in a keratin 8 (KRT8)-dependent manner. Knockdown of synaptosome-associated protein 29 (SNAP29) interfered with assembly and relaxed the filament-induced suppression of CTPS enzymatic activity. Furthermore, APEX2 proximity labeling of keratin 18 (KRT18) revealed a spatiotemporal association of SNAP29 with cytokeratin in response to stress. Super-resolution imaging suggests that during CTPS filament formation, SNAP29 interacts with CTPS along the cytokeratin network. This study links the cytokeratin network to the regulation of metabolism by compartmentalization of metabolic enzymes during nutrient deprivation.

Recent developments of two-color operation modes at X-ray free-electron laser facilities provide new research opportunities, such as X-ray pump/X-ray probe experiments and multiple-wavelength anomalous dispersion phasing methods. However, most existing indexing methods were developed for indexing diffraction data from monochromatic X-ray beams. Here, a new algorithm is presented for indexing two-color diffraction data, as an extension of the sparse-pattern indexing algorithm SPIND, which has been demonstrated to be capable of indexing diffraction patterns with as few as five peaks. The principle and implementation of the two-color indexing method, SPIND-TC, are reported in this paper. The algorithm was tested on both simulated and experimental data of protein crystals. The results show that the diffraction data can be accurately indexed in both cases. Source codes are publicly available at https://github.com/lixx11/SPIND-TC.

Black holes sound wildly complicated. After all, there are all sorts of bizarre things going on: intense gravity, the warping of the fabric of space, the distortion of time itself. But when it comes to describing black holes, it comes down to just two numbers: the mass of the black hole and its spin. That’s right. Everything you physically need to describe a black hole is found in just these two numbers.

The post Black Holes, just two numbers is all you need… appeared first on Smithsonian Insider.

The post Conservators challenged by contemporary artworks at the Hirshhorn Museum appeared first on Smithsonian Insider.

Keeper Tracey Barnes talks about Billie Jean, an Andean bear, and her two new cubs at the Smithsonian's National Zoo.

The post Keeper Tracey Barnes talks about the National Zoo’s Andean bear, Billie Jean, and her two new cubs appeared first on Smithsonian Insider.

The post Many years of research are celebrated in the December 2010 birth of two cheetah cubs at the Smithsonian Conservation Biology Institute appeared first on Smithsonian Insider.

The post With the recent hatching of two Cuban crocodiles, the National Zoo just got a little snappier! appeared first on Smithsonian Insider.

More than 154 million treasures fill the Smithsonian’s vaults, but where public view ends, Sidedoor begins. With the help of biologists, artists, historians, archaeologists, zookeepers […]

The post Sidedoor Season Two appeared first on Smithsonian Insider.

Smithsonian plant physiologist Bert Drake has studied one wetland's response to climate change for more than two decades. He gives a tour of the field experiment and explains some of the findings.

The post On the Chesapeake Bay, Smithsonian plant physiologist Bert Drake has been studying one wetland’s response to climate change for more than two decades. appeared first on Smithsonian Insider.

Going for the gut will soon become standard protocol for scientists working to unravel the complex living web of interactions between plants and animals on […]

The post Going for the gut: DNA from beetle stomachs reveals complex network appeared first on Smithsonian Insider.

A 57-acre research plot at a University of Michigan forest preserve northwest of Ann Arbor has been added to a Smithsonian Institution global network used […]

The post University of Michigan forest preserve joins Smithsonian global network appeared first on Smithsonian Insider.

Smithsonian scientists have discovered two new gecko species—the Lenya banded bent-toed gecko (Cyrtodactylus lenya) and Tenasserim Mountain bent-toed gecko (C. payarhtanesnsis)—in the little-studied lowland forests […]

The post Smithsonian Scientists Discover Two New Gecko Species in Vanishing Myanmar Rainforest appeared first on Smithsonian Insider.

The post Global forest network cracks the case of tropical biodiversity appeared first on Smithsonian Insider.

The addition of tert-butyl hydro­peroxide (tBuOOH) to two MnII complexes, differing by a small synthetic alteration from an ethyl to a propyl linker in the ligand scaffold, results in the formation of the high-valent bis-oxo complexes, {[MnIV{N4(6-Me-DPEN)}]2(μ-O)2}2+ (1) and {[MnIV{N4(6-Me-DPPN)}]2(μ-O)2}2+ (2).

One of the essential components of molecular electronic circuits are switching elements that are stable in two different states and can ideally be switched on and off many times. Here, distinct buckminsterfullerenes within a self-assembled monolayer, forming a two-dimensional dodecagonal quasicrystal on a Pt-terminated Pt3Ti(111) surface, are identified to form well separated molecular rotational switching elements. Employing scanning tunneling microscopy, the molecular-orbital appearance of the fullerenes in the quasicrystalline monolayer is resolved. Thus, fullerenes adsorbed on the 36 vertex configuration are identified to exhibit a distinctly increased mobility. In addition, this finding is verified by differential conductance measurements. The rotation of these mobile fullerenes can be triggered frequently by applied voltage pulses, while keeping the neighboring molecules immobile. An extensive analysis reveals that crystallographic and energetic constraints at the molecule/metal interface induce an inequality of the local potentials for the 36 and 32.4.3.4 vertex sites and this accounts for the switching ability of fullerenes on the 36 vertex sites. Consequently, a local area of the 8/3 approximant in the two-dimensional fullerene quasicrystal consists of single rotational switching fullerenes embedded in a matrix of inert molecules. Furthermore, it is deduced that optimization of the intermolecular interactions between neighboring fullerenes hinders the realization of translational periodicity in the fullerene monolayer on the Pt-terminated Pt3Ti(111) surface.

For several versions of Windows

The com­pound poly[2-hy­droxy-N-methyl­ethan-1-aminium [μ3-cyanido-κ3C:C:N-di-μ-cyanido-κ4C:N-dicuprate(I)]], {(C3H10NO)[Cu2(CN)3]}n or [meoenH]Cu2(CN)3, crystallizes in the tetra­gonal space group P43. The structure consists of a three-dimensional (3D) anionic CuICN network with noncoordinated protonated N-methyl­ethano­lamine cations providing charge neutrality. Pairs of cuprophilic Cu atoms are bridged by the C atoms of μ3-cyanide ligands, which link these units into a 43 spiral along the c axis. The spirals are linked together into a 3D anionic network by the two other cyanide groups. The cationic moieties are linked into their own 43 spiral via N—H⋯O and O—H⋯O hydrogen bonds, and the cations inter­act with the 3D network via an unusual pair of N—H⋯N hydrogen bonds to one of the μ2-cyanide groups. Thermogravimetric analysis indicates an initial loss of the base cation and one cyanide as HCN at temperatures in the range 130–250 °C to form CuCN. We show how loss of a specific cyanide group from the 3D CuCN structure could form the linear CuCN structure. Further heating leaves a residue of elemental copper, isolated as the oxide.

A new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of disease and ultimately enhance diagnosis and treatment, says a new report from the National Research Council.

Renewed interest in exploration of the moon has the potential to benefit lunar science greatly and could evolve into a program facilitated by partnerships between commercial companies and NASA’s Science Mission Directorate (SMD), say companion reports by the National Academies of Sciences, Engineering, and Medicine.

The National Academies of Sciences, Engineering, and Medicine and the National Science Foundation announced today the formation of a Societal Experts Action Network (SEAN) to connect social and behavioral science researchers with decision-makers who are leading the response to COVID-19. SEAN will respond to the most pressing social, behavioral, and economic questions that are being asked by federal, state, and local officials by working with appropriate experts to quickly provide actionable answers.

A little girl licking a spoon after stirring the cake mixture in 1935. ; Credit: Fox Photos/Getty Images

“How in the world am I going to come up with something to make dinner tonight?”

If you’ve found yourself asking this question repeatedly during the pandemic, you’re not alone. Grocery shopping complicated by COVID-19 and shortages of certain staples has meant that many who might not usually consider themselves home chefs have had no choice but to throw an apron on and do some culinary experimentation with whatever they already have in their kitchen and pantry. 

Last month on AirTalk, we tackled this issue by calling up pro chef Noelle Carter and food writer Russ Parson, both of whom are former members of the L.A. Times’ Food team, to answer your questions about how to cook with what you already have, recycle  certain foods, and even make staples that you might not be able to find in abundance right now. If you tuned in last time, you learned how to make your own pasta, how to regrow vegetables like green onions and romaine lettuce, and even what you can use as a substitute for all-purpose flour if you can’t find any at the store.

Today on AirTalk, we’re bringing Noelle and Russ back to help you out in the kitchen! If you’ve got questions about things like making or substituting ingredients, or need some ideas for what to make out of random ingredients in your fridge, join our live conversation by calling 866-893-5722.

Guests:

Noelle Carter, chef, food writer and culinary consultant for Noelle Carter Food, a website sharing recipes, cooking techniques and helpful kitchen tips for the home cook; she is the former director of the Los Angeles Times Test Kitchen; she tweets @noellecarter

Russ Parsons, former food editor and columnist for The Los Angeles Times for more than 20 years; he is the author of two cookbooks: “How To Pick A Peach” and “How To Read A French Fry”; he tweets @Russ_Parsons1

This content is from Southern California Public Radio. View the original story at SCPR.org.

Amoeba Music store, a Hollywood landmark is closed amid the COVID- 19 pandemic, on May 7, 2020, in Hollywood, California. ; Credit: VALERIE MACON/AFP via Getty Images

The City and County of Los Angeles began the process today of reopening some parts of the economy that had been shuttered due to COVID-19. 

Starting today, businesses including book stores, toy stores, sporting goods stores, florists and other “low-risk” retailers will be allowed to reopen for curbside service only. All other shopping will still need to be done over the phone or online. Businesses will also have to have strategies in place for stemming the spread of COVID-19 on site, which will need to include employee training, sanitation protocols and even screening measures. Offices, dine-in restaurants and shopping malls remain closed, as do beauty salons, barbershops, live event venues and other places where people might be in close proximity. Meanwhile, in Orange County, the final stretches of coastline were approved to reopen on Thursday, though they are under the same “active use” rules that the other beaches in OC have implemented in order to prevent people from congregating on beaches and in parking lots.

Today on AirTalk, we’ll talk about the specifics of what is and is not reopening today in L.A. City and County, get an update from the Los Angeles Flower Market in downtown, and find out about the latest on Orange County Beaches.

Guests:

Emily Guerin, reporter for KPCC covering small businesses; she tweets @guerinemily

Lisa Brenner, associate editor at LAist; she tweets @lisa_brenner

Laylan Connelly, beaches reporter for The Orange County Register; she tweets @ocbeaches

Candice Kim, whose parents owns a flower shop in Downtown LA that reopened today.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Updates for the critical-rated vulnerabilities, which are being actively exploited in the wild, are still weeks away

The post Microsoft warns of two Windows zero‑day flaws appeared first on WeLiveSecurity

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