sf Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion By www.jci.org Published On :: BACKGROUND Glucose-6-phosphate dehydrogenase (G6PD) deficiency decreases the ability of red blood cells (RBCs) to withstand oxidative stress. Refrigerated storage of RBCs induces oxidative stress. We hypothesized that G6PD-deficient donor RBCs would have inferior storage quality for transfusion as compared with G6PD-normal RBCs.METHODS Male volunteers were screened for G6PD deficiency; 27 control and 10 G6PD-deficient volunteers each donated 1 RBC unit. After 42 days of refrigerated storage, autologous 51-chromium 24-hour posttransfusion RBC recovery (PTR) studies were performed. Metabolomics analyses of these RBC units were also performed.RESULTS The mean 24-hour PTR for G6PD-deficient subjects was 78.5% ± 8.4% (mean ± SD), which was significantly lower than that for G6PD-normal RBCs (85.3% ± 3.2%; P = 0.0009). None of the G6PD-normal volunteers (0/27) and 3 G6PD-deficient volunteers (3/10) had PTR results below 75%, a key FDA acceptability criterion for stored donor RBCs. As expected, fresh G6PD-deficient RBCs demonstrated defects in the oxidative phase of the pentose phosphate pathway. During refrigerated storage, G6PD-deficient RBCs demonstrated increased glycolysis, impaired glutathione homeostasis, and increased purine oxidation, as compared with G6PD-normal RBCs. In addition, there were significant correlations between PTR and specific metabolites in these pathways.CONCLUSION Based on current FDA criteria, RBCs from G6PD-deficient donors would not meet the requirements for storage quality. Metabolomics assessment identified markers of PTR and G6PD deficiency (e.g., pyruvate/lactate ratios), along with potential compensatory pathways that could be leveraged to ameliorate the metabolic needs of G6PD-deficient RBCs.TRIAL REGISTRATION ClinicalTrials.gov NCT04081272.FUNDING The Harold Amos Medical Faculty Development Program, Robert Wood Johnson Foundation grant 71590, the National Blood Foundation, NIH grant UL1 TR000040, the Webb-Waring Early Career Award 2017 by the Boettcher Foundation, and National Heart, Lung, and Blood Institute grants R01HL14644 and R01HL148151. Full Article
sf IBM & Apple Expand Partnership to Help Transform Medical Research By www.ibm.com Published On :: Mon, 13 Apr 2015 09:02:06 GMT IBM today announced its Health Cloud and Watson cognitive computing capabilities will support health data entered by customers in iOS apps using Apple's ResearchKit and HealthKit frameworks. The move, which complements IBM’s new Watson Health business unit, will arm medical researchers with a secure, open data storage solution, as well as access to IBM’s most sophisticated data analytics capabilities. Full Article Smarter Cities
sf ISS Turns to IBM Watson IoT to Transform Management of 25,000 Buildings Worldwide By www.ibm.com Published On :: Thu, 30 Jun 2016 11:26:52 GMT ISS, ISS A/S, a leading global provider of facility services, has signed a commercial agreement with IBM to use the power of Watson IoT to transform the management of over 25,000 buildings around the world. Full Article Smarter Cities
sf Faurecia Drives Digital Transformation with IBM Cloud By www.ibm.com Published On :: Tue, 12 Sep 2017 10:02:29 GMT IBM today announced that Faurecia, one of the world’s leading automotive suppliers, has selected IBM Cloud as a support of a major business transformation designed to accelerate digital manufacturing. Full Article IBM Analytics
sf IBM Expands Mobile-led Transformation for Enterprises By www.ibm.com Published On :: Thu, 15 Jun 2017 04:01:40 GMT IBM today announced an expansion of its mobile portfolio for enterprises as it continues to create analytics-driven and cognitive enabled enterprise iOS apps that enable organizations to accelerate digital reinvention and transform how businesses engage across industries. Full Article IBM MobileFirst
sf IBM Announces Planned Acquisition of Promontory to Transform Regulatory Compliance with Watson By www.ibm.com Published On :: Thu, 29 Sep 2016 03:01:01 GMT IBM today announced plans to acquire Promontory Financial Group, a global market-leading risk management and regulatory compliance consulting firm. Upon close, the capabilities of Promontory combined with IBM's deep industry expertise and Watson’s cognitive capabilities will directly address the massive operational effort and manual cost of escalating regulation and risk management requirements. Full Article Global Financing
sf IBM and Box Forge Global Partnership to Transform Work in the Cloud By www.ibm.com Published On :: Wed, 24 Jun 2015 04:01:38 GMT IBM and Box today announced a global partnership that will combine the best-in-class technologies and resources of both companies to transform work in the cloud. Together, the companies plan to integrate their existing products and services and develop new, innovative solutions targeted across industries and professions ranging from medical teams working on complex cases to individuals negotiating consumer loans by mobile phone to engineers and researchers identifying patterns in patents, reports and academic journals. Full Article IBM Social Business
sf M-Industry Transforms Its Mobile Workforce with IBM MobileFirst for iOS By www.ibm.com Published On :: Thu, 07 Sep 2017 12:03:48 GMT IBM today announced that M-Industry, one of the world’s largest private label consumer goods company and subsidiary of Switzerland’s largest retailer and supermarket chain, Migros Group, has launched a new IBM designed mobile offering to transform how product promoters work. Full Article Services and solutions
sf IBM and Salesforce Strengthen Strategic Partnership By www.ibm.com Published On :: Fri, 19 Jan 2018 12:27:48 GMT f Full Article All Topics
sf IBM Transforms FlashSystem to Help Drive Down the Cost of Data By www.ibm.com Published On :: Thu, 26 Oct 2017 12:01:44 GMT IBM today announced sweeping advances in its all-flash storage solutions and software to significantly drive down the costs of data and extend its solutions for hybrid and private cloud environments. Full Article Education
sf Twitter and IBM Form Global Partnership to Transform Enterprise Decisions By www.ibm.com Published On :: Sun, 14 Dec 2014 09:18:40 GMT Twitter and IBM today announced a landmark partnership that will help transform how businesses and institutions understand their customers, markets and trends – and inform every business decision. The alliance brings together Twitter data that distinctively represents the public pulse of the planet with IBM’s industry-leading cloud-based analytics, customer engagement platforms, and consulting services. Full Article Investors
sf GRUPO FAMSA coloca al cliente en el centro del negocio para impulsar su transformación digital con IBM By www.ibm.com Published On :: lun, 29 may 2017 05:13:54 GMT El actual entorno tecnológico impulsa a las empresas a transformar sus modelos de negocio en un escenario en donde, según la Organización para la Cooperación y el Desarrollo Económicos (OCDE), el 25% de la economía mundial será digital en los próximos cinco años. De esta forma, el uso de nuevas tecnologías se vuelve la pieza clave para asegurar tanto competitividad, como su alto desempeño. Full Article Global Technology Services
sf IBM lanza la primera plataforma cognitiva de servicios para transformar las operaciones de negocios By www.ibm.com Published On :: mié, 12 jul 2017 02:19:24 GMT IBM anunció hoy la primera plataforma de servicios basada en IBM Watson y construida en IBM Cloud para aumentar la inteligencia humana y ayudar a mejorar las operaciones de los proveedores de servicios a través de tecnologías cognitivas. Full Article Global Technology Services
sf BBVA lidera la transformación tecnológica de la banca en Latinoamérica y EE.UU. de la mano de IBM By www.ibm.com Published On :: vie, 09 mar 2018 11:00:33 GMT El Grupo BBVA acaba de formalizar un acuerdo con IBM para que esta firma asuma la operación y transformación de la infraestructura tecnológica actual de BBVA y el procesamiento de datos en América Latina y EE.UU., actualmente gestionada por su filial ATA en México. Full Article Global Technology Services
sf IBM y Universidad de Guadalajara, Acortan Brecha en Habilidades que Demanda a Profesionales, la Transformación Digital By www.ibm.com Published On :: vie, 08 sep 2017 12:14:35 GMT Como parte de su compromiso por contribuir con la tecnología más innovadora a la resolución de los desafíos y retos que enfrenta el mundo, IBM dio a conocer que seleccionó a CUCEA (Centro Universitario de Ciencias Económico y Administrativas) de la Universidad de Guadalajara (UdeG); a fin de poner en marcha en México la implementación del Programa IBM Skills Academy, con foco en competencias de tecnología de Nube. Full Article Cloud Computing
sf IBM presenta nuevo servicio de nube que da a los negocios la flexibilidad que requiere su transformación By www.ibm.com Published On :: mié, 08 nov 2017 07:57:08 GMT IBM anuncia el lanzamiento de IBM Cloud Private, una plataforma de software creada para los clientes que requieren la flexibilidad y capacidad de una nube pública en un ambiente privado. IBM Cloud Private transforma los sistemas de TI (Tecnologías de la Información) en un ambiente de nube flexible para crear un puente hasta las nubes públicas y acelerar el desarrollo de aplicativos. Full Article Cloud Computing
sf IBM Verse, el mail social, combina tecnologías Cloud, Social, Analytics e innovación en diseño para transformar la forma en que trabajamos By www.ibm.com Published On :: vie, 21 nov 2014 03:58:49 GMT IBM (NYSE: IBM) reinventa hoy el correo electrónico empresarial con una nueva oferta de colaboración social freemium que utiliza la tecnología de analítica integrada para dar a los empleados una nueva forma de conversar, encontrar a las personas y la información correcta rápidamente, y hacer su trabajo de manera eficiente. IBM Verse es el resultado de una inversión de US$100 millones en diseño e innovación, y reúne las plataformas líderes cloud, analytics, social y de seguridad de la compañía para transformar el futuro del trabajo. Full Article Mobile
sf Westpac NZ Selects IBM to Support Transformation to NZ's Leading Digital Bank By www.ibm.com Published On :: Sun, 14 Dec 2014 09:22:55 GMT IBM today announced that Westpac New Zealand, part of one of the world’s largest financial services institutions, has selected IBM’s private cloud technology to support its goal to be New Zealand’s leading digital bank. The new five year agreement is part of an extensive services and technology contract which includes Westpac migrating some of its business critical IT systems into IBM’s state-of-the-art Auckland data centre, enabling enhanced customer service. Full Article Mobile
sf El Tecnológico de Monterrey transforma gestión de talento con solución de tecnología social By www.ibm.com Published On :: lun, 27 ago 2018 05:43:49 GMT IBM dio a conocer que el Tecnológico de Monterrey está transformando la gestión del entorno laboral de todas sus unidades de negocios con su solución de gestión de talento, Kenexa. La solución permite a los profesionales de Talento y Cultura (Recursos Humanos) del Tecnológico de Monterrey, tomar decisiones estratégicas a fin de impulsar los resultados de negocio basadas en hechos, es decir, sobre la base del análisis de talento (reporteadores) de su tradicional encuesta de clima organizacional. Full Article All Topics
sf Ilusión, Fiorentina y David's Bridal abren la puerta a la transformación digital en la moda con IBM By www.ibm.com Published On :: jue, 15 nov 2018 04:15:52 GMT Diltex -empresa mexicana propietaria de las marcas Ilusión y Fiorentina, socios de Vanity Fair Brands y franquiciatarios de David's Bridal en México- e IBM, anunciaron que la compañía dedicada a la industria de la moda está mejorando la experiencia del cliente y fortaleciendo su producción, distribución y comercialización a través de su transformación digital. Full Article All Topics
sf CEMEX Transformará Digitalmente la Experiencia de sus Clientes a través de Colaboración con IBM By www.ibm.com Published On :: vie, 18 nov 2016 07:01:41 GMT CEMEX, S.A.B. de C.V. (BMV: CEMEXCPO), una de las compañías de materiales para la industria de la construcción líder en el mundo, e IBM (NYSE: IBM) anunciaron hoy que CEMEX llevará a cabo una importante transformación tecnológica diseñada para optimizar sus operaciones, mejorar notablemente la experiencia de sus clientes y aumentar la eficiencia del negocio. Full Article Business partners
sf Presenta Foro Soluciones para Habilitar la Transformación de la Empresa Digital en la Era Cognitiva By www.ibm.com Published On :: jue, 02 mar 2017 10:48:15 GMT Durante la cumbre Business Connect 2017 en la Ciudad de México, IBM presentó a la Transformación Digital como una de las áreas de mayor crecimiento para los negocios en 2017 y mostró cómo las soluciones cognitivas (de analítica avanzada, de nube, de engagement), están transformando la forma en la que trabajamos y vivimos. Full Article Services and solutions
sf Impulsa IBM ejes de cambio para la transformación de las empresas: datos, interacción y nube By www.ibm.com Published On :: mar, 16 jun 2015 02:52:55 GMT Las estrategias de negocio con las que organizaciones líderes están transformando su negocio para obtener mayores eficiencias se basan en tecnologías para mejorar el manejo de la información, la interacción con clientes y modelos de negocio en la nube. Estas tecnologías son impulsadas por IBM, reconociendo las necesidades de las compañías mexicanas. Full Article Software
sf Premian Banorte e IBM apps de estudiantes del Tec de Monterrey que transforman servicios bancarios dirigidos a los jóvenes By www.ibm.com Published On :: mar, 29 sep 2015 04:33:08 GMT Tres proyectos que proponen mejorar la interacción y la experiencia de los jóvenes usuarios con servicios bancarios móviles, fueron reconocidos hoy por Banorte, IBM y el Tec de Monterrey como resultado del Reto Banorte en el marco de la Semana i, que la institución educativa llevó a cabo del 21 al 25 de septiembre en todo el país. Full Article Analytics
sf GIG construye con Analítica de IBM la transformación de su negocio By www.ibm.com Published On :: lun, 02 may 2016 09:33:10 GMT GIG Desarrollos Inmobiliarios dio a conocer que está utilizando una solución de analítica de datos de IBM para transformar el área de ventas inmobiliarias. La herramienta les ha permitido acelarar hasta 6 veces el tiempo dedicado al procesamiento de datos para el cálculo de comisiones. Full Article Analytics
sf IBM y VON DER HEIDE unen esfuerzos para transformar las iniciativas de recursos humanos en resultados de negocio By www.ibm.com Published On :: jue, 21 jul 2016 05:22:52 GMT IBM y VON DER HEIDE, compañía especializada en servicios de consultoría de Recursos Humanos, informan que han firmado una importante alianza para expandir su oferta de servicios de Employee Engagement y HR Analytics en toda América Latina. Por medio de las tecnologías de IBM, esta alianza le permitirá a VON DER HEIDE brindar a sus clientes una oferta de consultoría única en el mercado, para transformar estrategias de talento en resultados de negocio. Full Article Analytics
sf Vodafone New Zealand launches Digital Vodafone 2021 transformation program in collaboration with IBM iX By www.ibm.com Published On :: Thu, 19 Jul 2018 06:10:56 GMT Vodafone New Zealand, a leading telecommunications services provider, and IBM (NYSE: IBM) today announced a partnership to deliver the Digital Vodafone 2021 program in New Zealand. The vision for Digital Vodafone 2021 is to create the most engaging digital customer experience by adopting agile as a way of working, embracing new technologies and simplifying business models. The program is supported by IBM iX, one of the world’s largest digital agencies and global business design partners. Full Article Cloud Computing
sf IBM et SAP annoncent des projets d’investissements majeurs pour accompagner les clients dans leur transformation numérique By www.ibm.com Published On :: jeu., 07 avr. 2016 10:02:02 GMT IBM (NYSE: IBM) et SAP SE (NYSE: SAP) annoncent aujourd’hui des projets communs pour accompagner leurs clients dans la modernisation de leurs systèmes et processus afin d’accélérer leur présence dans l’économie numérique. Les deux compagnies envisagent particulièrement d’innover ensemble pour créer de nouvelles solutions qui augmentent la valeur ajoutée du client en s’appuyant sur des extensions cognitives, des expériences client et utilisateur renforcées ainsi que des fonctionnalités sectorielles. Tout ceci doté de la SAP® Business Suite, du logiciel 4 SAP HANA® (SAP S/4HANA) et disponible sur site et dans le Cloud. Full Article Commerce
sf IBM et Cisco misent sur la puissance d'IBM Watson et de Cisco Spark pour transformer la façon de travailler By www.ibm.com Published On :: jeu., 30 juin 2016 03:53:48 GMT Les deux sociétés s'unissent afin de redéfinir le travail quotidien de millions de personnes Full Article Business partners
sf IBM et Hardis Group signent un accord mondial pour transformer la chaîne logistique à l'heure du client connecté By www.ibm.com Published On :: ven., 10 oct. 2014 12:43:06 GMT @IBM et Hardis Group signent un accord mondial pour transformer la chaîne logistique à l'heure du #client connecté #smartercommerce Full Article Global Business Solutions
sf Alior Bank transforme l’expérience bancaire pour ses clients grâce à une application IBM pour iPad tirant parti de l'analytique By www.ibm.com Published On :: ven., 18 sept. 2015 03:09:58 GMT lior Banque annonce aujourd’hui avoir choisi l’application IBM MobileFirst sur iOS pour apporter une transformation fondamentale à la façon dont les clients en Pologne interagissent avec leur banque. A l’aide d’un iPad, les professionnels des services bancaires pourront fournir une expérience plus dynamique et personnalisée aux clients en tirant avantage de la puissance de l’analyse prédictive, et ce de façon sécurisée, facile, rapide et disponible 24h/24. Full Article Mobile
sf ANZ, Commonwealth Bank, IBM, Scentre Group and Westpac Commence Live Pilot for Lygon, A Blockchain-based Platform to Transform the Bank Guarantee Process By www.ibm.com Published On :: Fri, 25 Oct 2019 04:29:32 GMT ANZ, Commonwealth Bank, IBM Scentre Group and Westpac have jointly launched a live pilot for Lygon, a new digital platform using blockchain technology to transform the way businesses obtain and manage bank guarantees that are often required as part of a retail property lease. Full Article All Topics
sf Successful blockchain trial for bank guarantees By www.ibm.com Published On :: Wed, 11 Oct 2017 05:28:32 GMT ANZ and Westpac have teamed with IBM (NYSE:IBM) and shopping centre operator Scentre Group and have now successfully digitised the bank guarantee process used for commercial property leasing. Full Article Banking and Financial Services
sf IBM Watson Health announces Australian-first collaboration with Icon Group to transform oncology care. By www.ibm.com Published On :: Wed, 11 Oct 2017 05:25:03 GMT Icon Group first in Australia to adopt world-leading technology as part of its comprehensive cancer care offering Full Article IBM Watson
sf satisfied with swamp By www.marriedtothesea.com Published On :: Tue, 24 Dec 2019 04:00:00 EST Today on Married To The Sea: satisfied with swampThe Worst Things For Sale is Drew's blog. It updates every day. Subscribe to the Worst Things For Sale RSS! Full Article autogen_comic
sf 5 B2B Marketing Plan Elements for A Successful Campaign By feedproxy.google.com Published On :: Tue, 12 Sep 2017 12:33:20 +0000 A marketing plan should be designed to suit the needs of a business and its external environment. If you are selling products or services to ... The post 5 B2B Marketing Plan Elements for A Successful Campaign appeared first on Saleschase Stories. Full Article Marketing B2B Marketing Plan
sf Transfer of pywer By lambda-the-ultimate.org Published On :: Thu, 12 Jul 2018 17:15:46 +0000 Guido van Rossum is "resigning" from being the Python BDFL: "I'm basically giving myself a permanent vacation from being BDFL, and you all will be on your own." Apparently running a language can be tiring... It will be interesting to see what happens next. Full Article Python
sf 7 Tips To Be A Successful Guest Blogger By feedproxy.google.com Published On :: Sat, 09 Jul 2011 14:56:00 EST Guest blogging or guest posting depending on how you call it is another way you can spread the word about your site by attracting visitors you might not normally get. If done right it’ll not only build good relationships with other sites but can drive that every so sought after targeted traffic to your site. The problem is getting it right, all too often guest posts are nothing but a long winded advertisement for their site that offers nothing of any real value. A spammy guest post won’t do you any good other then give your site a bad reputation. Here are some tips to be a successful guest blogger............ Full Article
sf Analysis of Einstein’s derivation of the Lorentz Transformation By feedproxy.google.com Published On :: Thu, 23 Jan 2020 14:48:07 +0000 Einstein’s derivation of the Lorentz Transformation is purely theoretical. This study shows how it is related to the physical phenomenon of time dilation and length contraction. The Lorentz Transformation was first derived using the conditions of time dilation and length contraction. Later, Albert Einstein has given a different derivation of the Lorentz Transformation by using... Full Article SFN Blogs Uncategorized
sf Time relativity transformation of coordinates By feedproxy.google.com Published On :: Tue, 03 Mar 2020 21:50:36 +0000 Without length contraction, time relativity transformation solves paradoxes and explains incongruent relativistic experiments, which allows us to build a transformation of coordinates without length contraction. For abscissa transformation, Figure 1 shows a spaceship in the frame of O1, its backend is at O1 and frontend at A1. At time zero the spaceship is stationary, from... Full Article SFN Blogs Uncategorized
sf Time relativity transformation of velocity By feedproxy.google.com Published On :: Thu, 19 Mar 2020 21:34:01 +0000 A discrepancy-free transformation of velocity is derived using the Time relativity transformation of coordinates because relativistic transformation of velocity creates a discrepancy. The relativistic transformation of velocity expresses the velocity u2 of an object q in frame 2 in terms of its velocity in frame 1. In frame 2 at time tq, the position of... Full Article SFN Blogs Uncategorized
sf How can we transform health and social care in Scotland? By feeds.iriss.org.uk Published On :: Wed, 31 Aug 2016 09:54:42 PDT Find out about the work Audit Scotland is doing on health and social care services.See it on Scoop.it, via Social services news Full Article
sf NFPA and ESFI work to reduce fatalities caused by electric shock drowning in pools and at marinas By feedproxy.google.com Published On :: Thu, 22 Jun 2017 12:37:24 PDT With summer in full swing, the National Fire Protection Association (NFPA) and Electrical Safety Foundation International (ESFI) are joining forces to remind people about the potential electrical hazards in swimming pools, hot tubs and spas, on board boats and in the waters surrounding boats, marinas and launch ramps. Full Article
sf Targeted Phishing Attacks Successfully Hacked Top Executives At 150+ Companies By feedproxy.google.com Published On :: Thu, 30 Apr 2020 07:33:42 PDT In the last few months, multiple groups of attackers successfully compromised corporate email accounts of at least 156 high-ranking officers at various firms based in Germany, the UK, Netherlands, Hong Kong, and Singapore. Dubbed 'PerSwaysion,' the newly spotted cyberattack campaign leveraged Microsoft file-sharing services—including Sway, SharePoint, and OneNote—to launch highly targeted Full Article
sf Sexual Dysfunction Therapeutic By calmaretherapeutics.com Published On :: Thu, 12 Oct 2017 19:57:31 -0400 This patented therapeutic compound effectively treats both male and female sexual dysfunction. Because it targets the central nervous system, it may not have the negative cardiovascular side effects of existing sexual dysfunction therapies that target the vascular system. This patented therapeutic was discovered through collaboration of a medical doctor with a research chemist, and is currently in Phase 2B clinical trials for males in order to obtain FDA approval. Full Article Life Sciences
sf Princeton offers admission to 13 transfer students in third year of reinstated program By www.princeton.edu Published On :: Wed, 06 May 2020 17:00:00 -0400 Princeton has offered admission to 13 transfer students for entry in fall 2020. Since being reinstated in 2018, the undergraduate transfer admission program has been aimed at encouraging applicants from low-income, military or community college backgrounds. Full Article
sf NSF RAPID grant awarded for study of how anxiety affects the spread of COVID-19 information By www.princeton.edu Published On :: Thu, 02 Apr 2020 13:53:28 -0400 Princeton researchers have been awarded a National Science Foundation RAPID grant to study how anxiety about COVID-19 influences how we learn and share information about the pandemic. Full Article
sf NSF RAPID grant backs Princeton research to track and contain pandemic By www.princeton.edu Published On :: Mon, 13 Apr 2020 13:06:00 -0400 The National Science Foundation has awarded emergency grants to two teams of Princeton researchers developing ways to better track and contain pandemics including COVID-19. Full Article
sf Princeton University endorses guidelines aimed at rapid transfer of COVID-19 solutions to public By www.princeton.edu Published On :: Fri, 17 Apr 2020 09:17:00 -0400 Princeton this week endorsed new guidelines aimed at accelerating the transition of the University's COVID-19 discoveries into solutions to protect health care workers and prevent, diagnose, treat and contain the pandemic. Full Article
sf EPA’s Pacific Southwest Region Transfers N-95 Masks to California Office of Emergency Services By www.epa.gov Published On :: Tue, 07 Apr 2020 00:00:00 -0400 SAN FRANCISCO -- Today, the U.S. Full Article