When NASA’s Voyager 2 spacecraft flew by Uranus in 1986, it provided scientists’ first close glimpse of this ice-giant planet.

The post Voyager 2’s Flyby of Uranus in 1986 was During Anomalous Solar Event, New Study Suggests appeared first on Sci.News: Breaking Science News.

People report greater life satisfaction six months after starting Parkrun events, which could partly be due to the supportive environment

“Cover, bring to a boil, then reduce heat. Simmer for 20 minutes.” These directions seem simple enough, and yet I have messed up many, many pots of rice over the years. My sympathies to anyone who’s ever had to boil rice on a stovetop, cook it in a clay pot over a kerosene or charcoal burner, or prepare it in a cast-iron cauldron. All hail the 1955 invention of the automatic rice cooker!

How the automatic rice cooker was invented

It isn’t often that housewives get credit in the annals of invention, but in the story of the automatic rice cooker, a woman takes center stage. That happened only after the first attempts at electrifying rice cooking, starting in the 1920s, turned out to be utter failures. Matsushita, Mitsubishi, and Sony all experimented with variations of placing electric heating coils inside wooden tubs or aluminum pots, but none of these cookers automatically switched off when the rice was done. The human cook—almost always a wife or daughter—still had to pay attention to avoid burning the rice. These electric rice cookers didn’t save any real time or effort, and they sold poorly.

But Shogo Yamada, the energetic development manager of the electric appliance division for Toshiba, became convinced that his company could do better. In post–World War II Japan, he was demonstrating and selling electric washing machines all over the country. When he took a break from his sales pitch and actually talked to women about their daily household labors, he discovered that cooking rice—not laundry—was their most challenging chore. Rice was a mainstay of the Japanese diet, and women had to prepare it up to three times a day. It took hours of work, starting with getting up by 5:00 am to fan the flames of a kamado, a traditional earthenware stove fueled by charcoal or wood on which the rice pot was heated. The inability to properly mind the flame could earn a woman the label of “failed housewife.”

In 1951, Yamada became the cheerleader of the rice cooker within Toshiba, which was understandably skittish given the past failures of other companies. To develop the product, he turned to Yoshitada Minami, the manager of a small family factory that produced electric water heaters for Toshiba. The water-heater business wasn’t great, and the factory was on the brink of bankruptcy.

How Sources Influence the Telling of History

As someone who does a lot of research online, I often come across websites that tell very interesting histories, but without any citations. It takes only a little bit of digging before I find entire passages copied and pasted from one site to another, and so I spend a tremendous amount of time trying to track down the original source. Accounts of popular consumer products, such as the rice cooker, are particularly prone to this problem. That’s not to say that popular accounts are necessarily wrong; plus they are often much more engaging than boring academic pieces. This is just me offering a note of caution because every story offers a different perspective depending on its sources.

For example, many popular blogs sing the praises of Fumiko Minami and her tireless contributions to the development of the rice maker. But in my research, I found no mention of Minami before Helen Macnaughtan’s 2012 book chapter, “Building up Steam as Consumers: Women, Rice Cookers and the Consumption of Everyday Household Goods in Japan,” which itself was based on episode 42 of the Project X: Challengers documentary series that was produced by NHK and aired in 2002.

If instead I had relied solely on the description of the rice cooker’s early development provided by the Toshiba Science Museum (here’s an archived page from 2007), this month’s column would have offered a detailed technical description of how uncooked rice has a crystalline structure, but as it cooks, it becomes a gelatinized starch. The museum’s website notes that few engineers had ever considered the nature of cooking rice before the rice-cooker project, and it refers simply to the “project team” that discovered the process. There’s no mention of Fumiko.

Both stories are factually correct, but they emphasize different details. Sometimes it’s worth asking who is part of the “project team” because the answer might surprise you. —A.M.

Although Minami understood the basic technical principles for an electric rice cooker, he didn’t know or appreciate the finer details of preparing perfect rice. And so Minami turned to his wife, Fumiko.

Fumiko, the mother of six children, spent five years researching and testing to document the ideal recipe. She continued to make rice three times a day, carefully measuring water-to-rice ratios, noting temperatures and timings, and prototyping rice-cooker designs. Conventional wisdom was that the heat source needed to be adjusted continuously to guarantee fluffy rice, but Fumiko found that heating the water and rice to a boil and then cooking for exactly 20 minutes produced consistently good results.

But how would an automatic rice cooker know when the 20 minutes was up? A suggestion came from Toshiba engineers. A working model based on a double boiler (a pot within a pot for indirect heating) used evaporation to mark time. While the rice cooked in the inset pot, a bimetallic switch measured the temperature in the external pot. Boiling water would hold at a constant 100 °C, but once it had evaporated, the temperature would soar. When the internal temperature of the double boiler surpassed 100 °C, the switch would bend and cut the circuit. One cup of boiling water in the external pot took 20 minutes to evaporate. The same basic principle is still used in modern cookers.

Yamada wanted to ensure that the rice cooker worked in all climates, so Fumiko tested various prototypes in extreme conditions: on her rooftop in cold winters and scorching summers and near steamy bathrooms to mimic high humidity. When Fumiko became ill from testing outside, her children pitched in to help. None of the aluminum and glass prototypes, it turned out, could maintain their internal temperature in cold weather. The final design drew inspiration from the Hokkaidō region, Japan’s northernmost prefecture. Yamada had seen insulated cooking pots there, so the Minami family tried covering the rice cooker with a triple-layered iron exterior. It worked.

How Toshiba sold its automatic rice cooker

Toshiba’s automatic rice cooker went on sale on 10 December 1955, but initially, sales were slow. It didn’t help that the rice cooker was priced at 3,200 yen, about a third of the average Japanese monthly salary. It took some salesmanship to convince women they needed the new appliance. This was Yamada’s time to shine. He demonstrated using the rice cooker to prepare takikomi gohan, a rice dish seasoned with dashi, soy sauce, and a selection of meats and vegetables. When the dish was cooked in a traditional kamado, the soy sauce often burned, making the rather simple dish difficult to master. Women who saw Yamada’s demo were impressed with the ease offered by the rice cooker.

Another clever sales technique was to get electricity companies to serve as Toshiba distributors. At the time, Japan was facing a national power surplus stemming from the widespread replacement of carbon-filament lightbulbs with more efficient tungsten ones. The energy savings were so remarkable that operations at half of the country’s power plants had to be curtailed. But with utilities distributing Toshiba rice cookers, increased demand for electricity was baked in.

Within a year, Toshiba was selling more than 200,000 rice cookers a month. Many of them came from the Minamis’ factory, which was rescued from near-bankruptcy in the process.

How the automatic rice cooker conquered the world

From there, the story becomes an international one with complex localization issues. Japanese sushi rice is not the same as Thai sticky rice which is not the same as Persian tahdig, Indian basmati, Italian risotto, or Spanish paella. You see where I’m going with this. Every culture that has a unique rice dish almost always uses its own regional rice with its own preparation preferences. And so countries wanted their own type of automatic electric rice cooker (although some rejected automation in favor of traditional cooking methods).

Yoshiko Nakano, a professor at the University of Hong Kong, wrote a book in 2009 about the localized/globalized nature of rice cookers. Where There Are Asians, There Are Rice Cookers traces the popularization of the rice cooker from Japan to China and then the world by way of Hong Kong. One of the key differences between the Japanese and Chinese rice cooker is that the latter has a glass lid, which Chinese cooks demanded so they could see when to add sausage. More innovation and diversification followed. Modern rice cookers have settings to give Iranians crispy rice at the bottom of the pot, one to let Thai customers cook noodles, one for perfect rice porridge, and one for steel-cut oats.

My friend Hyungsub Choi, in his 2022 article “Before Localization: The Story of the Electric Rice Cooker in South Korea,” pushes back a bit on Nakano’s argument that countries were insistent on tailoring cookers to their tastes. From 1965, when the first domestic rice cooker appeared in South Korea, to the early 1990s, Korean manufacturers engaged in “conscious copying,” Choi argues. That is, they didn’t bother with either innovation or adaptation. As a result, most Koreans had to put up with inferior domestic models. Even after the Korean government made it a national goal to build a better rice cooker, manufacturers failed to deliver one, perhaps because none of the engineers involved knew how to cook rice. It’s a good reminder that the history of technology is not always the story of innovation and progress.

Eventually, the Asian diaspora brought the rice cooker to all parts of the globe, including South Carolina, where I now live and which coincidentally has a long history of rice cultivation. I bought my first rice cooker on a whim, but not for its rice-cooking ability. I was intrigued by the yogurt-making function. Similar to rice, yogurt requires a constant temperature over a specific length of time. Although successful, my yogurt experiment was fleeting—store-bought was just too convenient. But the rice cooking blew my mind. Perfect rice. Every. Single. Time. I am never going back to overflowing pots of starchy water.

Part of a continuing series looking at historical artifacts that embrace the boundless potential of technology.

An abridged version of this article appears in the November 2024 print issue as “The Automatic Rice Cooker’s Unlikely Inventor.”

References

Helen Macnaughtan’s 2012 book chapter, “Building up Steam as Consumers: Women, Rice Cookers and the Consumption of Everyday Household Goods in Japan,” was a great resource in understanding the development of the Toshiba ER-4. The chapter appeared in The Historical Consumer: Consumption and Everyday Life in Japan, 1850-2000, edited by Penelope Francks and Janet Hunter (Palgrave Macmillan).

Yoshiko Nakano’s book Where There are Asians, There are Rice Cookers (Hong Kong University Press, 2009) takes the story much further with her focus on the National (Panasonic) rice cooker and its adaptation and adoption around the world.

The Toshiba Science Museum, in Kawasaki, Japan, where we sourced our main image of the original ER-4, closed to the public in June. I do not know what the future holds for its collections, but luckily some of its Web pages have been archived to continue to help researchers like me.

Every invention begins with a problem—and the creative act of seeing a problem where others might just see unchangeable reality. For one 5-year-old, the problem was simple: She liked to have her tummy rubbed as she fell asleep. But her mom, exhausted from working two jobs, often fell asleep herself while putting her daughter to bed. “So [the girl] invented a teddy bear that would rub her belly for her,” explains Stephanie Couch, executive director of the Lemelson MIT Program. Its mission is to nurture the next generation of inventors and entrepreneurs.

Anyone can learn to be an inventor, Couch says, given the right resources and encouragement. “Invention doesn’t come from some innate genius, it’s not something that only really special people get to do,” she says. Her program creates invention-themed curricula for U.S. classrooms, ranging from kindergarten to community college.

We’re biased, but we hope that little girl grows up to be an engineer. By the time she comes of age, the act of invention may be something entirely new—reflecting the adoption of novel tools and the guiding forces of new social structures. Engineers, with their restless curiosity and determination to optimize the world around them, are continuously in the process of reinventing invention.

In this special issue, we bring you stories of people who are in the thick of that reinvention today. IEEE Spectrum is marking 60 years of publication this year, and we’re celebrating by highlighting both the creative act and the grindingly hard engineering work required to turn an idea into something world changing. In these pages, we take you behind the scenes of some awe-inspiring projects to reveal how technology is being made—and remade—in our time.

Inventors Are Everywhere

Invention has long been a democratic process. The economist B. Zorina Khan of Bowdoin College has noted that the U.S. Patent and Trademark Office has always endeavored to allow essentially anyone to try their hand at invention. From the beginning, the patent examiners didn’t care who the applicants were—anyone with a novel and useful idea who could pay the filing fee was officially an inventor.

This ethos continues today. It’s still possible for an individual to launch a tech startup from a garage or go on “Shark Tank” to score investors. The Swedish inventor Simone Giertz, for example, made a name for herself with YouTube videos showing off her hilariously bizarre contraptions, like an alarm clock with an arm that slapped her awake. The MIT innovation scholar Eric von Hippel has spotlighted today’s vital ecosystem of “user innovation,” in which inventors such as Giertz are motivated by their own needs and desires rather than ambitions of mass manufacturing.

But that route to invention gets you only so far, and the limits of what an individual can achieve have become starker over time. To tackle some of the biggest problems facing humanity today, inventors need a deep-pocketed government sponsor or corporate largess to muster the equipment and collective human brainpower required.

When we think about the challenges of scaling up, it’s helpful to remember Alexander Graham Bell and his collaborator Thomas Watson. “They invent this cool thing that allows them to talk between two rooms—so it’s a neat invention, but it’s basically a gadget,” says Eric Hintz, a historian of invention at the Smithsonian Institution. “To go from that to a transcontinental long-distance telephone system, they needed a lot more innovation on top of the original invention.” To scale their invention, Hintz says, Bell and his colleagues built the infrastructure that eventually evolved into Bell Labs, which became the standard-bearer for corporate R&D.

In this issue, we see engineers grappling with challenges of scale in modern problems. Consider the semiconductor technology supported by the U.S. CHIPS and Science Act, a policy initiative aimed at bolstering domestic chip production. Beyond funding manufacturing, it also provides US $11 billion for R&D, including three national centers where companies can test and pilot new technologies. As one startup tells the tale, this infrastructure will drastically speed up the lab-to-fab process.

And then there are atomic clocks, the epitome of precision timekeeping. When researchers decided to build a commercial version, they had to shift their perspective, taking a sprawling laboratory setup and reimagining it as a portable unit fit for mass production and the rigors of the real world. They had to stop optimizing for precision and instead choose the most robust laser, and the atom that would go along with it.

These technology efforts benefit from infrastructure, brainpower, and cutting-edge new tools. One tool that may become ubiquitous across industries is artificial intelligence—and it’s a tool that could further expand access to the invention arena.

What if you had a team of indefatigable assistants at your disposal, ready to scour the world’s technical literature for material that could spark an idea, or to iterate on a concept 100 times before breakfast? That’s the promise of today’s generative AI. The Swiss company Iprova is exploring whether its AI tools can automate “eureka” moments for its clients, corporations that are looking to beat their competitors to the next big idea. The serial entrepreneur Steve Blank similarly advises young startup founders to embrace AI’s potential to accelerate product development; he even imagines testing product ideas on digital twins of customers. Although it’s still early days, generative AI offers inventors tools that have never been available before.

Measuring an Invention’s Impact

If AI accelerates the discovery process, and many more patentable ideas come to light as a result, then what? As it is, more than a million patents are granted every year, and we struggle to identify the ones that will make a lasting impact. Bryan Kelly, an economist at the Yale School of Management, and his collaborators made an attempt to quantify the impact of patents by doing a technology-assisted deep dive into U.S. patent records dating back to 1840. Using natural language processing, they identified patents that introduced novel phrasing that was then repeated in subsequent patents—an indicator of radical breakthroughs. For example, Elias Howe Jr.’s 1846 patent for a sewing machine wasn’t closely related to anything that came before but quickly became the basis of future sewing-machine patents.

Another foundational patent was the one awarded to an English bricklayer in 1824 for the invention of Portland cement, which is still the key ingredient in most of the world’s concrete. As Ted C. Fishman describes in his fascinating inquiry into the state of concrete today, this seemingly stable industry is in upheaval because of its heavy carbon emissions. The AI boom is fueling a construction boom in data centers, and all those buildings require billions of tons of concrete. Fishman takes readers into labs and startups where researchers are experimenting with climate-friendly formulations of cement and concrete. Who knows which of those experiments will result in a patent that echoes down the ages?

Some engineers start their invention process by thinking about the impact they want to make on the world. The eminent Indian technologist Raghunath Anant Mashelkar, who has popularized the idea of “Gandhian engineering”, advises inventors to work backward from “what we want to achieve for the betterment of humanity,” and to create problem-solving technologies that are affordable, durable, and not only for the elite.

Durability matters: Invention isn’t just about creating something brand new. It’s also about coming up with clever ways to keep an existing thing going. Such is the case with the Hubble Space Telescope. Originally designed to last 15 years, it’s been in orbit for twice that long and has actually gotten better with age, because engineers designed the satellite to be fixable and upgradable in space.

For all the invention activity around the globe—the World Intellectual Property Organization says that 3.5 million applications for patents were filed in 2022—it may be harder to invent something useful than it used to be. Not because “everything that can be invented has been invented,” as in the apocryphal quote attributed to the unfortunate head of the U.S. patent office in 1889. Rather, because so much education and experience are required before an inventor can even understand all the dimensions of the door they’re trying to crack open, much less come up with a strategy for doing so. Ben Jones, an economist at Northwestern’s Kellogg School of Management, has shown that the average age of great technological innovators rose by about six years over the course of the 20th century. “Great innovation is less and less the provenance of the young,” Jones concluded.

Consider designing something as complex as a nuclear fusion reactor, as Tom Clynes describes in “An Off-the-Shelf Stellarator.” Fusion researchers have spent decades trying to crack the code of commercially viable fusion—it’s more akin to a calling than a career. If they succeed, they will unlock essentially limitless clean energy with no greenhouse gas emissions or meltdown danger. That’s the dream that the physicists in a lab in Princeton, N.J., are chasing. But before they even started, they first had to gain an intimate understanding of all the wrong ways to build a fusion reactor. Once the team was ready to proceed, what they created was an experimental reactor that accelerates the design-build-test cycle. With new AI tools and unprecedented computational power, they’re now searching for the best ways to create the magnetic fields that will confine the plasma within the reactor. Already, two startups have spun out of the Princeton lab, both seeking a path to commercial fusion.

The stellarator story and many other articles in this issue showcase how one innovation leads to the next, and how one invention can enable many more. The legendary Dean Kamen, best known for mechanical devices like the Segway and the prosthetic “Luke” arm, is now trying to push forward the squishy world of biological manufacturing. In an interview, Kamen explains how his nonprofit is working on the infrastructure—bioreactors, sensors, and controls—that will enable companies to explore the possibilities of growing replacement organs. You could say that he’s inventing the launchpad so others can invent the rockets.

Sometimes everyone in a research field knows where the breakthrough is needed, but that doesn’t make it any easier to achieve. Case in point: the quest for a household humanoid robot that can perform domestic chores, switching effortlessly from frying an egg to folding laundry. Roboticists need better learning software that will enable their bots to navigate the uncertainties of the real world, and they also need cheaper and lighter actuators. Major advances in these two areas would unleash a torrent of creativity and may finally bring robot butlers into our homes.

And maybe the future roboticists who make those breakthroughs will have cause to thank Marina Umaschi Bers, a technologist at Boston College who cocreated the ScratchJr programming language and the KIBO robotics kit to teach kids the basics of coding and robotics in entertaining ways. She sees engineering as a playground, a place for children to explore and create, to be goofy or grandiose. If today’s kindergartners learn to think of themselves as inventors, who knows what they’ll create tomorrow?

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Organizing business events can be a challenge. There’s always the concern that guests will lose interest or become disengaged. When organizing team-building activities and office parties, it becomes essential to add something extra that keeps everyone active and involved. That way, the event not only meets expectations but exceeds them, leaving people excited and talking […]

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Data is essential for any organization. This isn’t a new concept, and it’s not one that should be a surprise, but it

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Researchers say tornadoes in Harvey, Sheffield areas on Friday evening were record-breaking for the province.

Nintendo is set to show off the Donkey Kong Country expansion of its Super Nintendo World theme park today (Monday, November 11) at 5PM ET, the company revealed in a post on X. That means the new Universal Studios Japan area might finally open soon, after being delayed from the previously announced launch window of Spring 2024. 

The new park attraction featuring Mario's barrel-throwing nemesis was first revealed in 2021. The centerpiece is a ride called Mine Cart Madness, named after the best level in the 1994 SNES game Donkey Kong Country. After being blasted out of a barrel cannon, you'll take a mine cart ride through the jungle that includes a "leap across a collapsed track" as Nintendo showed in a render earlier this year.  

The direct livestream appears to be focused on Donkey Kong world alone, and Nintendo specifically pointed out that "no game information will be featured" — so don't expect any news on the next-gen Switch 2 console either. 

Donkey Kong Country will expand the park size by up to 70 percent, Nintendo said when it was announced. Current attractions at the Japan park are the Mario Kart: Kuppa's Challenge rollercoaster and Yoshi Adventure. Nintendo recently announced that it would open a Super Nintendo World attraction at Universal Studios Orlando on May 22nd, 2025 with the same attractions as the park in Osaka. 

For the first time in over two years, Overwatch 2 players will be able to group up in teams of six. A three-week event featuring that format starts tomorrow, November 12. But there’s a twist: you won’t be able to select Kiriko or Sombra, or battle it out with an additional player on each side on Push maps just yet. That’s because in Overwatch 2’s first real taste of 6v6, Blizzard is taking us all the way back to the beginning with a limited-time mode called Overwatch: Classic.

You will be able to experience Overwatch almost exactly as it was upon its May 2016 debut. That means you can choose from the first 21 heroes, who all have their original kits and abilities. That means Hanzo loses his Lunge jump but regains his dreaded Scatter Arrow, Bastion and Torbjorn are vastly different than they are now and Cassidy's Flashbang once again stun locks enemies for a moment. 

Symmetra reverts to being a support who can teleport allies almost anywhere on the map from the spawn room, while Mercy can will once again bring five dead teammates back to life. Ultimate abilities will charge up faster too.

In addition, just like in Overwatch for a brief period at the very beginning, there are initially no limits on hero selection. So if you and your teammates want to run with a composition of four Winstons and two Lucios, have at it. However, this will only apply for the first few days, after which Blizzard will apply the single hero limit rule for the rest of the event. Games will take place under the Quick Play ruleset, rather than the Competitive format.

The original 12 maps will be available too — including the assault maps that Blizzard retired from the main modes during the transition to Overwatch 2. While assault maps are still available in the Arcade and custom games, you'll once again be dealing with the notorious choke points of the otherwise gorgeous Hanamura, Temple of Anubis and Volskaya Industries.

Things won't be exactly as they were in May 2016, however. Original maps that have seen major reworks over the years — Dorado, Numbani, Route 66 and Watchpoint: Gibraltar — will appear as they are in the current game. You'll only be able to use the original default Overwatch skins and no, there are no loot boxes. The user interface remains the same too, which hopefully means the ping system will still be in place.

Blizzard doesn't plan for this to be a one-and-done deal. There will be other Overwatch: Classic events in the future, focusing on various moments in the game's history, like the infamous triple-tank, triple-support GOATS meta. This limited-time mode is also separate from the other 6v6 tests Blizzard plans to run in the coming months as it looks to measure players' interest in that format and garner feedback.

There's a good chance that this limited-time mode will bring some lapsed players back into the mix, even just for a sip of nostalgia. I first played Overwatch several months after its debut, so it'll be fun to see roughly how the game felt at the very beginning. I will be instalocking Mei every match so I can remember what it's like to freeze an opponent before giving them a cheeky wave and firing an icicle into their skull. Ah, memories...

On apprend aujourd’hui que certains CPE, subventionnés avec votre argent, pratiquent une discrimination scandaleuse dans l’accueil des enfants.

They can cost hundreds of pounds, but are these products actually worth the money?

Over the past 20 years, technological advances have enabled inventors to go from strength to strength. And yet, according to the legendary inventor Dean Kamen, innovation has stalled. Kamen made a name for himself with inventions including the first portable insulin pump for diabetics, an advanced wheelchair that can climb steps, and the Segway mobility device. Here, he talks about his plan for enabling innovators.

How has inventing changed since you started in the 1990s?

Dean Kamen: Kids all over the world can now be inventing in the world of synthetic biology the way we played with Tinkertoys and Erector Sets and Lego. I used to put pins and smelly formaldehyde in frogs in high school. Today in high school, kids will do experiments that would have won you the Nobel Prize in Medicine 40 years ago. But none of those kids are likely in any short time to be on the market with a pharmaceutical that will have global impact. Today, while invention is getting easier and easier, I think there are some aspects of innovation that have gotten much more difficult.

Can you explain the difference?

Kamen: Most people think those two words mean the same thing. Invention is coming up with an idea or a thing or a process that has never been done that way before. [Thanks to] more access to technology and 3D printers and simulation programs and virtual ways to make things, the threshold to be able to create something new and different has dramatically lowered.

Historically, inventions were only the starting point to get to innovation. And I’ll define an innovation as something that reached a scale where it impacted a piece of the world, or transformed it: the wheel, steam, electricity, Internet. Getting an invention to the scale it needs to be to become an innovation has gotten easier—if it’s software. But if it’s sophisticated technology that requires mechanical or physical structure in a very competitive world? It’s getting harder and harder to do due to competition, due to global regulatory environments.

[For example,] in proteomics [the study of proteins] and genomics and biomedical engineering, the invention part is, believe it or not, getting a little easier because we know so much, because there are development platforms now to do it. But getting a biotech product cleared by the Food and Drug Administration is getting more expensive and time consuming, and the risks involved are making the investment community much more likely to invest in the next version of Angry Birds than curing cancer.

A lot of ink has been spilled about how AI is changing inventing. Why hasn’t that helped?

Kamen: AI is an incredibly valuable tool. As long as the value you’re looking for is to be able to collect massive amounts of data and being able to process that data effectively. That’s very different than what a lot of people believe, which is that AI is inventing and creating from whole cloth new and different ideas.

How are you using AI to help with innovation?

Kamen: Every medical school has incredibly brilliant professors and grad students with petri dishes. “Look, I can make nephrons. We can grow people a new kidney. They won’t need dialysis.” But they only have petri dishes full of the stuff. And the scale they need is hundreds and hundreds of liters.

I started a not-for-profit called ARMI—the Advanced Regenerative Manufacturing Institute—to help make it practical to manufacture human cells, tissues, and organs. We are using artificial intelligence to speed up our development processes and eliminate going down frustratingly long and expensive [dead-end] paths. We figure out how to bring tissue manufacturing to scale. We build the bioreactors, sensor technologies, robotics, and controls. We’re going to put them together and create an industry that can manufacture hundreds of thousands of replacement kidneys, livers, pancreases, lungs, blood, bone, you name it.

So ARMI’s purpose is to help would-be innovators?

Kamen: We are not going to make a product. We’re not even going to make a whole company. We’re going to create baseline core technologies that will enable all sorts of products and companies to emerge to create an entire new industry. It will be an innovation in health care that will lower costs because cures are much cheaper than chronic treatments. We have to break down the barriers so that these fantastic inventions can become global innovations.

This article appears in the November 2024 print issue as “The Inventor’s Inventor.”

Manu Prakash spoke with IEEE Spectrum shortly after returning to Stanford University from a month aboard a research vessel off the coast of California, where he was testing tools to monitor oceanic carbon sequestration. The associate professor conducts fieldwork around the world to better understand the problems he’s working on, as well as the communities that will be using his inventions.

Prakash develops imaging instruments and diagnostic tools, often for use in global health and environmental sciences. His devices typically cost radically less than conventional equipment—he aims for reductions of two or more orders of magnitude. Whether he’s working on pocketable microscopes, mosquito or plankton monitors, or an autonomous malaria diagnostic platform, Prakash always includes cost and access as key aspects of his engineering. He calls this philosophy “frugal science.”

Why should we think about science frugally?

Manu Prakash: To me, when we are trying to ask and solve problems and puzzles, it becomes important: In whose hands are we putting these solutions? A frugal approach to solving the problem is the difference between 1 percent of the population or billions of people having access to that solution.

Lack of access creates these kinds of barriers in people’s minds, where they think they can or cannot approach a kind of problem. It’s important that we as scientists or just citizens of this world create an environment that feels that anybody has a chance to make important inventions and discoveries if they put their heart to it. The entrance to all that is dependent on tools, but those tools are just inaccessible.

How did you first encounter the idea of “frugal science”?

Prakash: I grew up in India and lived with very little access to things. And I got my Ph.D. at MIT. I was thinking about this stark difference in worlds that I had seen and lived in, so when I started my lab, it was almost a commitment to [asking]: What does it mean when we make access one of the critical dimensions of exploration? So, I think a lot of the work I do is primarily driven by curiosity, but access brings another layer of intellectual curiosity.

How do you identify a problem that might benefit from frugal science?

Prakash: Frankly, it’s hard to find a problem that would not benefit from access. The question to ask is “Where are the neglected problems that we as a society have failed to tackle?” We do a lot of work in diagnostics. A lot [of our solutions] beat the conventional methods that are neither cost effective nor any good. It’s not about cutting corners; it’s about deeply understanding the problem—better solutions at a fraction of the cost. It does require invention. For that order of magnitude change, you really have to start fresh.

Where does your involvement with an invention end?

Prakash: Inventions are part of our soul. Your involvement never ends. I just designed the 415th version of Foldscope [a low-cost “origami” microscope]. People only know it as version 3. We created Foldscope a long time ago; then I realized that nobody was going to provide access to it. So we went back and invented the manufacturing process for Foldscope to scale it. We made the first 100,000 Foldscopes in the lab, which led to millions of Foldscopes being deployed.

So it’s continuous. If people are scared of this, they should never invent anything [laughs], because once you invent something, it’s a lifelong project. You don’t put it aside; the project doesn’t put you aside. You can try to, but that’s not really possible if your heart is in it. You always see problems. Nothing is ever perfect. That can be ever consuming. It’s hard. I don’t want to minimize this process in any way or form.

Neurogene’s Rett syndrome gene therapy has preliminary data supporting safety and efficacy of the one-time treatment. But a late-breaking report of a serious complication in a patient who received the high dose sent shares of the biotech downward.

The post Neurogene Gene Therapy Shows Signs of Efficacy in Small Study, But an Adverse Event Spooks Investors appeared first on MedCity News.

Nov 17, 2022

The speakers included Yale Law School professor Harold H. Koh ’75, and Patrick W. Pearsall, Director of the International Claims and Reparations Project at Columbia Law School. Koh and Pearsall discussed their experiences representing Ukraine in legal proceedings against Russia before the International Court of Justice.

Nov 18, 2022

Former Colombian President Iván Duque discussed Latin America’s resurgent left wing and advocated for environmental action at the Harvard Kennedy School on Thursday afternoon.

Apr 10, 2023

The following is an event write-up about the recent Future of Diplomacy Project (FDP) seminar on “The Geopolitics of Latin America amid the War in Ukraine and China-U.S. Tensions” moderated by Negah Angha, Fellow at the Institute of Politics, on March 29, 2023.

Apr 18, 2023

The following is an event write-up about the recent Future of Diplomacy Project (FDP) seminar on “The Future of Ukraine: Reconstruction, Energy Security, and Innovation” moderated by Ambassador Paula J. Dobriansky, Senior Fellow with the Future of Diplomacy Project. 

Nov 26, 2020

• Elbe Group Discusses Strategic Stability, Hybrid Warfare and Terrorism.
• Mowatt-Larssen’s Book Details Lessons He Learned While Tracking Al-Qaida’s WMD Programs.
• Experts on New START Extension and Other Nuclear Priorities of Biden Presidency.
• Kazakhstan’s Last HEU Eliminated.
• William Potter Joins Russian Academy of Sciences.
• COVID, Nuclear Security On Agenda of IAEA’s 64th General Conference.
• Mayak Aims to Process Entire range of SNF.
• Atomguard Reports Foiling Unauthorized Access.
• Allison: US Vital Interest in Prevention of Nuclear Terrorism Will Continue to Guide Its North Korea Policy.
• Learning from COVID-19 to Prepare for Nuclear Attack.
• Hecker, Kassianova Encourage Young US and RF Professionals to Explore Lessons of Nuclear Accidents.
• Experts Weigh in on 75th Anniversary of Hiroshima Bombing.
• A New Look at IAEA’s Nuclear Security Recommendations.
• Azerbaijan Has Threatened to Strike Armenia’s NPP With Missiles.
• IAEA Notified of 189 Incidents Of Material Being Out Of Regulatory Control in 2019.
• Russia To Retrieve More Radioactive Debris from Bottom of Ocean.
• Researchers Propose Fast Way to Detect Weapons Grade Materials.
• Keeping Nuclear Power Plants Out of Reach of Terrorists During the Coronavirus Pandemic.
• Bunn, Tobey and Roth Testify on Prevention of Nuclear Theft, Call for Cooperation With Russia.
• Budapest Memorandum Parsed.
• IAEA Holds A Ministerial on Nuclear Security.
• Assessing Progress on Nuclear Security.
• 12^th GUMO Officer On Trial for Embezzlement.
• Lukashenko: Pompeo Alerted Me to Nuclear Materials at Border.
• US and Russia Reported HEU and Plutonium to IAEA.
• IAEA Bank Receives LEU.
• GICNT Hosted 8 Multilateral Activities in 2019.

Dec 10, 2021

• U.S.-Russia Elbe Group Maintains Focus on Threat of Nuclear Terrorism.
• Former Chernobyl Plant Manager Bryukhanov Dies.
• Matthew Bunn on Threat to Nuclear and Radiological Transports.
• On 9/11 Anniversary Russian Officials Call for Resumption of U.S.-Russian CT Cooperation.
• Experts Weigh in on 9/11 Anniversary.
• U.S. and Norway Agree to Eliminate All of Norway’s HEU.
• Two Soviet Nuclear Submarine Reactors Located.
• Russian Security Council: Terrorists Remain Interested in NBC.
• IAEA Adopts Resolutions on Nuclear Security, NS Center Planned.
• Allison on Risk of Mega-terrorist Attack After U.S. Withdrawal From Afghanistan.
• Arbatov Warns of Enduring Threat of Nuclear Terrorism to Russia in His New Volume.
• Russia’s New Security Strategy Drops References to CT Partnership With U.S.
• NNSA’s Non-Proliferation Budget to Decrease in ’22, Provides for US and Russian Visits.
• Should U.S.-Russian Interaction in Cyberspace Involve CT? 
• Russia’s NPP Operator Conducts Emergency Preparedness Exercise.
• Putin and Biden Discuss Terrorist Threat Emanating from Afghanistan, but No Deal.
• U.S. Experts on Ensuring Access to Neutrons While Reducing Nuclear Terrorism Risks.
• Beebe Weighs in on U.S.-Russian CT Interaction.
• Duo Detained for Alleged Attempt to Sell Americium-241.
• 12th GUMO Guard’s Sentence Upheld.
• NDAA-Mandated Group to Identify Nuclear Terrorism Risks.
• Belfer’s MTA Hosts Conference on Lessons of Fukushima and Chernobyl.
• Russia Withdraws from Uranium Hexafluoride Transportation Deal with U.S.
• Bell: U.S. Needs to Convince Russia on Contending With Nuclear Terrorism Threat.
• U.S. and Canada Complete Repatriation of HEU Material.
• Siegfried Hecker Outlines his Vision of Future for Nuclear Security Cooperation.
• Hackers Breach U.S. Nuclear Agency.
• Tobey on Assassinations of Nuclear Scientists and Terrorists.
• Rosatom Has Checked Nuclear Sites, Following a Tip on Terrorism from U.S.

Dec 13, 2023

The Harvard Project on Climate Agreements (HPCA) assembled a panel of leading academics and government officials to discuss strategies for achieving significant methane emissions reductions at relatively low costs at an official COP 28 Side Event last Wednesday (Dec. 6). The event, titled “Reducing Global Methane Emissions: Imperatives, Opportunities, and Challenges,” was moderated by HPCA Director Robert Stavins.

Apr 8, 2024

Joseph Nye argues that the "one China" formula, if combined with other measures to bolster deterrence against any sudden acts of aggression, can still help to keep the peace.

Jun 5, 2024

Harvard Kennedy School hosted Leah Stokes, Anton Conk Associate Professor of Environmental Politics at UC Santa Barbara, to discuss how the historic Inflation Reduction Act succeeded where so many previous climate bills failed.

Mar 18, 2024

Harvard Kennedy School hosted Jahi Wise, Senior Adviser to the Administrator of the U.S. Environmental Protection Agency, to discuss the design and implementation of the Greenhouse Gas Reduction Fund, a historic investment in American clean energy technology finance.

Apr 1, 2024

Harvard Kennedy School hosted Sarah Ladislaw, Special Assistant to the President and Senior Director for Climate and Energy of the U.S. National Security Council, for an Energy Policy Seminar on the U.S. approach to energy and climate issues in its foreign policy.

Apr 26, 2024

Concerns over resource adequacy during periods of peak demand or supply crises are rising with increasing deployment of renewable energy. Conleigh Byers says mandatory forward market contracts could help.

Jun 6, 2024

Emily Grubert, Associate Professor of Sustainable Energy Policy and of Civil and Environmental Engineering and Earth Sciences at the University of Notre Dame, discussed the dangers of an unplanned transition from a fossil-based energy system to a zero-carbon energy system during a talk at Harvard Kennedy School.

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