Middle East and North Africa

Research on the Middle East and North Africa region focuses on changes to politics and society, economics, and security issues.

This is a turbulent period for the region following the Arab Spring, with conflict in Syria continuing to impact its neighbours, governance in Libya under scrutiny, and increasing pressures on the Gulf monarchies, especially around human rights.   

Key research areas include the Gulf States and the Gulf Cooperation Council (GCC), the future of the state, mapping the region’s war economies, the Yemen conflict, Iraq’s reconstruction, and the influence of Saudi Arabia and Iran.

Cullin RING E3 Ligases (CRLs) ubiquitylate hundreds of important cellular substrates. Here we have assembled and purified the Ankyrin repeat and SOCS Box protein 9 CUL5 RBX2 Ligase (ASB9-CRL) in vitro and show how it ubiquitylates one of its substrates, CKB. CRLs occasionally collaborate with RING between RING E3 ligases (RBRLs) and indeed, mass spectrometry analysis showed that CKB is specifically ubiquitylated by the ASB9-CRL-ARIH2-UBE2L3 complex. Addition of other E2s such as UBE2R1 or UBE2D2 contribute to polyubiquitylation but do not alter the sites of CKB ubiquitylation. Hydrogen-deuterium exchange mass spectrometry (HDX-MS) analysis revealed that CUL5 neddylation allosterically exposes its ARIH2 binding site, promoting high affinity binding, and it also sequesters the NEDD8 E2 (UBE2F) binding site on RBX2. Once bound, ARIH2 helices near the Ariadne domain active site are exposed, presumably relieving its autoinhibition. These results allow us to propose a model of how neddylation activates ASB-CRLs to ubiquitylate their substrates.

The Angels agreed to terms with right-hander reliever Daniel Hudson on a Minor League deal to add bullpen depth, a source confirmed to MLB.com on Friday.

VOLUME 279 (2004) PAGES 33438–33446For Fig. 1B, the second, third, and fifth panels were mistakenly duplicated during article preparation as no yeast colonies were observed in these conditions. The corrected images are presented in the revised Fig. 1B. This correction does not affect the results or conclusions of the work. The authors apologize for the error.jbc;295/50/17382/F1F1F1Figure 1B.

VOLUME 289 (2014) PAGES 6604–6618In Fig. 4G, in the foxi1 panel, the images in Fig. 4G, i and l, corresponding to “smad1 MO” and “smad5 MO + samd1/9 mRNA” samples, respectively, were inadvertently reused during figure preparation. This error has now been corrected using images pertaining to each treatment and sample. This correction does not affect the results or conclusions of the work.jbc;295/52/18650/F4F1F4Figure 4G.

Middle East and great power competition 28 November 2022 — 12:00PM TO 1:00PM Anonymous (not verified) 25 October 2022 Chatham House and Online

Experts discuss how the Middle East is changing in a fast-moving geopolitical environment.

The war in Ukraine and great power competition define not only global politics but also regional ones. The Middle East is a microcosm for observing how the great power rivalry informs regional affairs.

OPEC+’s decision to reduce oil supply to international markets and many regional states’ balancing act between the West and Russia, for that matter China as well, are only a few recent policy choices that clearly illustrate how the global and regional levels interact with each other.

Plus this is now a region in which the US has downsized its security commitments, whereas Russia has increased its footprint in regional security and China in economy.

This event tries to unpack how the great power rivalry and the war in Ukraine affect regional politics and how the Middle East adjusts itself to this new phase in global politics.

How Oslo adds a touch of style to the UN The World Today rsoppelsa.drupal 25 May 2022

Seventy years ago, Norway paid for the interior of ‘the most important room in the world’. Now it’s rediscovering the soft power of its design heritage

The view from the roof terrace of Oslo’s newest museum takes in the deep blue fjord and harbour but also the recently opened Munch Museum, whose tilting tower leans over the white iceberg of the opera house. All are emblematic of the transformation of Norway’s capital, one of Europe’s fastest growing cities, into a cultural destination.  

The £500 million National Museum, which opens on June 11, is another statement building in a city which has tended to value modesty over self-promotion. Locals may call it ‘the bunker’ but Denise Hagströmer, a senior curator who compiled its design galleries, believes the museum’s monumental scale and the range of its displays mark a change in Norway’s idea of itself: ‘The country that in the past was thought of as the “little brother” of Scandinavia is now speaking with a completely different voice.’

Norway, with a population of only 5.5 million people, has a history of excelling when it comes to using cultural soft power as a tool of foreign policy, says Hagströmer. 

One of the exhibits in the design galleries is the blue and gold wallpaper used in the United Nations Security Council Chamber in New York, dubbed ‘the most important room in the world’. In here, the Security Council imposes sanctions, dispatches peacekeeping missions and authorizes the use of force.

Designed by Else Poulsson, the Norwegian textile artist, its motifs represent faith, hope and love, reflecting the aspirations of the UN.  

Norway’s decision to pay for the interior of the Security Council Chamber 70 years ago came at a time when the country was recovering from Nazi occupation, while the oil that would make it rich had yet to be discovered. Trygve Lie, the first UN Secretary-General, a Norwegian Labour politician, is said to have played a central role in pushing the project, intended to show the effectiveness of design as a cultural ambassador. 

‘Norway elevated its position on the world stage and achieved an oversized presence at the UN for such a small country,’ says Sarah Lichtman, a design historian from the Parsons School of Design in New York. Even though it doesn’t have a permanent seat on the Security Council, Norway embedded its identity in the room through the legacy of the architecture and interior design, she adds.  

While other Scandinavian architects in the UN complex went for the fashionable modernist look in the Trusteeship and Economic and Social Council chambers, Norwegian Arnstein Arneberg opted for a more classic, even conservative style. In a letter to the Norwegian Foreign Ministry, he wrote: ‘This interior must represent Norway in a worthy manner.’ 

As well as Poulsson, Arneberg hired his fellow countryman Per Krohg to paint a giant mural. Krohg, who had been a prisoner of the Nazis in the Second Word War, turned his commission into an altarpiece to peace. ‘The world we abandoned cannot be erased just like that, but one can build a bridge over the adversity and from that journey to a new society,’ he said of his mural, which measures five metres by nine metres. 

The connection between design and politics is explored further in the new Oslo museum’s design galleries and in a separate exhibition, Scandinavian Design & the United States, which show how Nordic objects were charged with democratic values in the post-war period.  ‘Design plays an important role in the Cold War battles that are not just about bombs and missiles but also about lifestyle and ideology,’ says the Swedish writer, Sara Kristoffersson.  

Scandinavian design is rooted in egalitarian ideals of social democracy. Ornate decoration that valued one object above another was replaced with clean forms, craftsmanship and natural materials such as leather, wood and wool, says Astrid Skjerven, a professor at the department of product design at Oslo Metropolitan University.

Shortly after the Security Council chamber was completed, Norwegian designers participated with Danes, Swedes and Finns in the Design in Scandinavia exhibition that was hugely popular in America in the mid-1950s. 

The Norwegians, who were the least known internationally, had the most to gain from the three-year tour, with stores in Manhattan showcasing their designs. First Lady Jacqueline Kennedy and Emperor Hirohito of Japan each bought pieces by the Norwegian designer Torbjørn Afdal.

Norway’s neighbours capitalized on the international demand for Scandi style by supporting their furniture makers with state funding, promotional campaigns abroad and a national design strategy. 

Yet despite creating prize-winning, mid-century pieces, Norway ended up as ‘the underdog of Nordic design’, according to Morten Hippe, a Norwegian industrial designer, who in 2016 started a company, Eikund, to reproduce furniture from the golden era of Norwegian design. The market in Norway for these goods was tiny, and the discovery of oil in 1969 meant many craftsmen moved to more lucrative jobs. 

Across the Atlantic, Norwegian soft power had made its mark in the halls of the UN. By 2006, the Security Council Chamber and the rest of the UN complex needed renovating. The permanent members stipulated that restoration work must preserve the chamber in its original form. 

They also insisted on having the room duplicated in their temporary space elsewhere in the UN building, with a smaller photographic reproduction of the Krohg mural. The painting had become integral to the function of the room, argues Lichtman – ‘like Picasso’s Guernica or one of those paintings with a moralizing tale that reminds the people in the room of the horrors of war’. Norway gave $5 million to the restoration, which was finished in 2013.

Recently, Norwegian diplomats also realized that design could be used more broadly to communicate values and ideas. A new, minimalist passport was issued in 2020 which reflects Norway’s reputation for design excellence.

When the country’s joint consulate and UN mission in New York had to move location, it was an opportunity to create an open-plan office that reflected the non-hierarchical structure of most private and public bodies back home. 

The corner office, with the best views, has a communal table that everyone can use. The room’s design has echoes of a wooden cabin, the typical weekend bolt hole for many Norwegians. Carpets resemble a forest floor, birdsong plays in the bathrooms and futuristic ‘Extreme’ chairs designed by Terje Ekstrom are framed by views of Manhattan. Consul General Heidi Olufsen says visitors to the offices are taken aback when they find a little slice of Norwegian life.

Olufsen’s official residence is sparer and more elegant. The mid-century dining table and chairs designed by Fredrik Kayser are from Eikund and the bright velvet Bollo chairs by Andreas Engesvik, seen by many as the country’s top furniture designer. Olufsen wants the decor to make guests ‘feel they are in the modern Norway of 2022’, she says, with more to offer than just mountains and fjords. 

Yet Olufsen admits there is still a way to go: ‘We still have more to do to boost our self-confidence and demand more space for Norwegian design.’ 
 

Turkey's Foreign Policy in the Middle East 14 May 2019 — 12:30PM TO 1:30PM Anonymous (not verified) 29 April 2019 Chatham House | 10 St James's Square | London | SW1Y 4LE

Turkey is cooperating closely with Russia to secure its border with Syria and to encourage a long-term political resolution to the Syrian conflict. Its efforts have staved off a humanitarian catastrophe in the northern Syrian province of Idlib and initiated the trilateral ‘Astana Process’ with Russia and Iran as the primary framework to settle the future of Syria.

By contrast, Turkey and the US disagree on a range of important issues including Turkey’s purchase of the Russian-made S-400 air missile defence systems and American support for the PKK-affiliated Peoples’ Protection Units (YPG) in Syria.

In this session, the speaker will outline Turkey’s foreign policy priorities in the Middle East and share his country’s perspectives on the US and Russian policies in that region.

Attendance at this event is by invitation only.

An additional five rhesus macaque monkeys that escaped from a South Carolina research facility last week have been recovered, meaning about a dozen of the rhesus macaque primates remain at large.

Loopholes in international laws governing the use of incendiary weapons in warfare are allowing warring parties in Ukraine and the Middle East to exploit the use of such weapons without adequately protecting civilians.

Justin Herbert, Russell Wilson and Quentin Johnston lead UPI senior sports writer Alex Butler's fantasy football waiver wire priority list for Week 11 of the 2024 NFL season.

A 77-year-old slice of cake from Queen Elizabeth II's wedding to Prince Philip was auctioned for $2,800.

There are really two stories packaged in the most recent MLPerf  Training 4.0 results, released today. The first, of course, is the results. Nvidia (currently king of accelerated computing) wins […]

The post MLPerf Training 4.0 – Nvidia Still King; Power and LLM Fine Tuning Added appeared first on HPCwire.

WASHINGTON, Oct. 30, 2024 — The U.S. Department of the Treasury (Treasury) today issued a final rule (Final Rule) to implement Executive Order 14105 of August 9, 2023, “Addressing United […]

The post US Treasury Issues Final Rule Addressing Investments in Certain National Security Technologies and Products appeared first on HPCwire.

U.S. Defense Secretary Lloyd Austin has pledged to get to the bottom of reports of military personnel experiencing mysterious illnesses while overseas.

The nation's depleted supply of IV solutions is recovering after a North Carolina facility recently resumed production after Hurricane Helene temporarily put it out of business.

Two additional cases of a new strain of mpox have been detected in Britain, national health officials said Monday, less than a week after the first case was announced to the public.

An additional case of a new strain of mpox has been detected in Britain, bringing the total number of infections in the country to four.

The fantastic Supercomputing 2024 show is coming back to Atlanta this year. If last year was any indication, there will be plenty of coffee flowing and lots of discussions around […]

The post Top500 Wild Cards Could Add Thrills to Supercomputing 2024 Show appeared first on HPCwire.

An additional five rhesus macaque monkeys that escaped from a South Carolina research facility last week have been recovered, meaning about a dozen of the rhesus macaque primates remain at large.

The fate of fictional Montana Gov. John Dutton -- played by Kevin Costner -- has finally been disclosed in the Season 5B premiere of "Yellowstone" that aired on Paramount Sunday night.

Peacock anounced four more guest stars for "Poker Face" Season 2 on Tuesday, though no premiere date yet.

President Joe Biden and Israeli President Isaac Herzog met at the White House on Tuesday afternoon to discuss the war against Hamas and Hezbollah and other Middle East concerns.

Discover the hidden force shaping your social habits—and why you’re not even aware of it.

What we eat is less about what we choose and more about what’s offered to us, says food and climate expert Sarah Lake. Unpacking how governments and companies have driven up meat consumption in the US through extensive marketing, she explains how we could employ these same forces to incentivize plant-based eating — for the sake of the planet, public health and global food security.

Addiction isn’t a condition that just affects your behavior; it also affects your brain and body. Therefore, to recover from addiction, it’s not enough to simply quit using substances. Your brain also has to undergo certain changes to detox and recuperate. Knowing how the brain heals from addiction can help throw light on the science […]

The post How the Brain Heals from Addiction first appeared on What is Psychology?.

Parents of a child with autism filed lawsuits against the Clark County, Nev. district, after video evidence showed him being restrained repeatedly.

When schools reduce racial segregation between schools, racial isolation within the classes inside those schools goes up, according to an analysis of 20 years of North Carolina data.

Kyle Connor could be the NHL's most underrated player, even after the Winnipeg Jets got off to a historic start. He could also become a bona fide star at the 4 Nations Face-Off.

The Oilers look to claw themselves up above .500 against the team that started their memorable turnaround last season.

Indiana's magical season makes rare move into the College Football Playoff top five despite an embarrassingly easy schedule

Jacy Sheldon and Katie Smith are both returning to their alma mater to join the staff ran by Kevin McGuff.

Five-star wing Deniya Prawl has committed to Lady Vols basketball, marking a significant recruiting win in Kim Caldwell's first year at Tennessee.

Notre Dame sophomore guard Hannah Hidalgo is on the Women’s Basketball Coaches Association (WBCA) Wade Watch List. She's among 15 players being watched as a potential winner of the oldest, most prestigious player of the year award. She was a Region I finalist for…

Lady Vols basketball relied on its best 3-point shooting night of the season to close out a win over Middle Tennessee State on Tuesday

Luke Clark
Nov 6, 2013; 33:17617-17623
Symposium and Mini-Symposium

Sharon G. Kujawa
Nov 11, 2009; 29:14077-14085
BehavioralSystemsCognitive

A new Deputy Director-General of Programmes (DDP) was created at the end of last year. As we are all aware, the strategic programmes, liaison offices as well as OPC now [...]

World Food Day is coming up this Monday, October 16. This year’s theme, Change the future of migration. Invest in food security and rural development, highlights FAO’s work in [...]

Click here to access the presentation by QU Dongyu.

By the 1930s, the black middle class had arrived, with the purchasing power to match. Sensing an opportunity, developers established Idlewild: a summer resort aimed exclusively at African-Americans.

Astrophysicist Stephen Murray explains how X-ray energies can be used to understand dark matter and its place in the universe

Local Burmese fisher Maung Lay shows how his family has traditionally teamed up with rare river dolphins and explains why their partnership is now at risk. (Video by Demelza Stokes and Mark Scialla)